148
|
401
|
7e3nA |
Crystal structure of isocitrate dehydrogenase d252n mutant from trypanosoma brucei in complexed with nadp+, alpha-ketoglutarate, and ca2+ |
138
|
410
|
7pjnB |
Crystal structure of ivosidenib-resistant idh1 variant r132c s280f in complex with nadph and inhibitor ds-1001b |
143
|
410
|
7pjnA |
Crystal structure of ivosidenib-resistant idh1 variant r132c s280f in complex with nadph and inhibitor ds-1001b |
154
|
415
|
7pjmA |
Crystal structure of ivosidenib-resistant idh1 variant r132c s280f in complex with nadph and ca2+/2-oxoglutarate |
275
|
723
|
7y1uA |
Crystal structure of isocitrate dehydrogenase from campylobacter corcagiensis |
140
|
410
|
8hb9AAA |
Crystal structure of human idh1 r132h mutant in complex with nadph and compound ihmt-idh1-053 |
153
|
414
|
8bayA |
Crystal structure of idh1 variant r132c s280f in complex with nadph, ca2+ and 3-butyl-2-oxoglutarate |
149
|
411
|
6io0A |
Human idh1 r132c mutant complexed with compound a. |
274
|
739
|
5kvuA |
Crystal structure of isocitrate dehydrogenase-2 in complex with nadp(+) from mycobacterium tuberculosis |
215
|
735
|
5z16A |
A novel dimeric isocitrate dehydrogenase from acinetobacter baumannii |
148
|
409
|
5yziA |
Crystal structure of mouse cytosolic isocitrate dehydrogenase complexed with cadmium |
123
|
418
|
5m2eA |
Apo structure of pseudomonas aeruginosa isocitrate dehydrogenase, icd. |
147
|
414
|
5lgeA |
Crystal structure of human idh1 mutant (r132h) in complex with nadp+ and an inhibitor related to bay 1436032 |
132
|
412
|
5l58A |
Crystal structure of iso-citrate dehydrogenase 1 [idh1 (r132h)] in complex with a novel inhibitor (compound 2) |
142
|
412
|
5l57A |
Crystal structure of iso-citrate dehydrogenase r132h in complex with a novel inhibitor (compound 13a) |
142
|
414
|
5icdA |
Regulation of an enzyme by phosphorylation at the active site |
155
|
413
|
5i95A |
Crystal structure of human mitochondrial isocitrate dehydrogenase r140q mutant homodimer bound to nadph and alpha-ketoglutaric acid |
158
|
417
|
5i96A |
Crystal structure of human mitochondrial isocitrate dehydrogenase (idh2) r140q mutant homodimer in complex with ag-221 (enasidenib) inhibitor. |
138
|
414
|
9icdA |
Catalytic mechanism of nadp+-dependent isocitrate dehydrogenase: implications from the structures of magnesium-isocitrate and nadp+ complexes |
138
|
414
|
8icdA |
Regulation of an enzyme by phosphorylation at the active site |
140
|
414
|
7icdA |
Regulation of an enzyme by phosphorylation at the active site |
141
|
414
|
6icdA |
Regulation of an enzyme by phosphorylation at the active site |
140
|
419
|
6c0eA |
Crystal structure of isocitrate dehydrogenase from legionella pneumophila with bound nadph with an alpha-ketoglutarate adduct |
162
|
416
|
6bl0A |
Novel modes of inhibition of wild-type idh1:direct covalent modification of his315 with cmpd11 |
158
|
414
|
6bkxA |
Novel modes of inhibition of wild-type idh1: direct covalent modification of his315 with cmpd1 |
160
|
416
|
6bl1A |
Novel modes of inhibition of wild-type idh1: direct covalent modification of his315 with cmpd13 |
156
|
416
|
6bkyA |
Novel binding modes of inhibition of wild-type idh1: allosteric inhibition with cmpd2 |
148
|
412
|
6bkzA |
Novel modes of inhibition of wild-type idh1: non-equivalent allosteric inhibition with cmpd3 |
159
|
416
|
6bl2A |
Novel modes of inhibition of wild-type idh1: direct covalent modification of his315 with cmpd15 |
145
|
410
|
6b0zA |
Idh1 r132h mutant in complex with idh305 |
156
|
418
|
6adiA |
Crystal structures of idh2 r140q in complex with ag-881 |
144
|
412
|
6adgA |
Crystal structures of idh1 r132h in complex with ag-881 |
157
|
412
|
5yzhA |
Crystal structure of mouse cytosolic isocitrate dehydrogenase |
151
|
418
|
5yfnA |
Human isocitrate dehydrogenase 1 bound with isocitrate |
151
|
409
|
5yfmA |
Human isocitrate dehydrogenase 1 bound with nadp |
263
|
735
|
4zdaA |
Crystal structure of isocitrate dehydrogenase in complex with isocitrate and mn from m. smegmatis |
130
|
410
|
4xs3A |
Crystal structure of a metabolic reductase with (e)-1-benzyl-5-((1-methyl-5-oxo-2-thioxoimidazolidin-4-ylidene)methyl)pyridin-2(1h)-one |
143
|
411
|
4umyA |
Idh1 r132h in complex with cpd 1 |
141
|
412
|
4umxA |
Idh1 r132h in complex with cpd 1 |
140
|
415
|
4bnpA |
3d structure of e. coli isocitrate dehydrogenase k100m mutant in complex with isocitrate and magnesium(ii) |
153
|
402
|
4aovA |
Dpidh-nadp. the complex structures of isocitrate dehydrogenase from clostridium thermocellum and desulfotalea psychrophila, support a new active site locking mechanism |
138
|
416
|
4aj3A |
3d structure of e. coli isocitrate dehydrogenase in complex with isocitrate, calcium(ii) and nadp - the pseudo-michaelis complex |
144
|
401
|
4aouA |
Ctidh bound to nadp. the complex structures of isocitrate dehydrogenase from clostridium thermocellum and desulfotalea psychrophila, support a new active site locking mechanism |
140
|
415
|
4ajcA |
3d structure of e. coli isocitrate dehydrogenase k100m mutant in complex with alpha-ketoglutarate, calcium(ii) and adenine nucleotide phosphate |
137
|
415
|
4ajrA |
3d structure of e. coli isocitrate dehydrogenase k100m mutant in complex with alpha-ketoglutarate, magnesium(ii) and nadph - the product complex |
122
|
400
|
4aoyA |
Open ctidh. the complex structures of isocitrate dehydrogenase from clostridium thermocellum and desulfotalea psychrophila, support a new active site locking mechanism |
142
|
415
|
4ajbA |
3d structure of e. coli isocitrate dehydrogenase k100m mutant in complex with isocitrate, magnesium(ii) and thionadp |
141
|
415
|
4ajaA |
3d structure of e. coli isocitrate dehydrogenase in complex with isocitrate, calcium(ii) and thionadp |
138
|
415
|
4ajsA |
3d structure of e. coli isocitrate dehydrogenase k100m mutant in complex with isocitrate, magnesium(ii), adenosine 2',5'-biphosphate and ribosylnicotinamide-5'-phosphate |
143
|
401
|
3us8A |
Crystal structure of an isocitrate dehydrogenase from sinorhizobium meliloti 1021 |