Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 1ihi_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): TYR 3.A OH ASP 76.A OD1 no hydrogen 2.650 N/A CYS 5.A SG TYR 3.A O no hydrogen 3.652 N/A VAL 6.A N MET 14.A O no hydrogen 2.690 N/A LYS 7.A NZ GLY 11.A O no hydrogen 3.214 N/A LEU 8.A N HIS 12.A O no hydrogen 2.701 N/A ASN 9.A ND2 PRO 184.A O no hydrogen 3.054 N/A ASN 9.A ND2 ASP 208.A O no hydrogen 3.264 N/A GLY 11.A N LEU 8.A O no hydrogen 2.908 N/A HIS 12.A N ASP 10.A OD1 no hydrogen 2.989 N/A MET 14.A N VAL 6.A O no hydrogen 2.962 N/A VAL 16.A N GLN 4.A O no hydrogen 2.941 N/A GLY 18.A N VAL 265.A O no hydrogen 2.625 N/A PHE 19.A N HIS 46.A O no hydrogen 2.706 N/A THR 21.A N ASP 48.A O no hydrogen 3.178 N/A THR 21.A OG1 ASP 48.A O no hydrogen 2.900 N/A TYR 22.A OH GLU 222.A OE1 no hydrogen 2.477 N/A VAL 27.A N PRO 24.A O no hydrogen 2.875 N/A LYS 31.A N PRO 28.A O no hydrogen 3.234 N/A ALA 32.A N LYS 29.A O no hydrogen 2.683 N/A GLU 34.A N SER 30.A O no hydrogen 3.171 N/A ALA 35.A N LYS 31.A O no hydrogen 2.928 N/A VAL 36.A N ALA 32.A O no hydrogen 3.093 N/A LYS 37.A N LEU 33.A O no hydrogen 3.337 N/A LEU 38.A N GLU 34.A O no hydrogen 3.230 N/A ALA 39.A N ALA 35.A O no hydrogen 2.932 N/A ILE 40.A N VAL 36.A O no hydrogen 2.827 N/A GLU 41.A N LYS 37.A O no hydrogen 3.019 N/A ALA 42.A N LEU 38.A O no hydrogen 2.957 N/A GLY 43.A N ALA 39.A O no hydrogen 3.126 N/A GLY 43.A N ILE 40.A O no hydrogen 3.033 N/A PHE 44.A N ALA 39.A O no hydrogen 3.117 N/A HIS 45.A ND1 ASP 76.A O no hydrogen 2.722 N/A HIS 46.A ND1 PRO 15.A O no hydrogen 3.142 N/A ILE 47.A N PHE 78.A O no hydrogen 2.850 N/A ASP 48.A N PHE 19.A O no hydrogen 2.897 N/A SER 49.A N THR 80.A O no hydrogen 3.044 N/A SER 49.A OG ASN 55.A OD1 no hydrogen 2.748 N/A ALA 50.A N SER 49.A OG no hydrogen 2.598 N/A ASN 54.A N HIS 51.A O no hydrogen 2.771 N/A ASN 55.A ND2 THR 21.A OG1 no hydrogen 3.178 N/A VAL 59.A N ASN 55.A O no hydrogen 2.883 N/A GLY 60.A N GLU 56.A O no hydrogen 2.781 N/A LEU 61.A N GLU 57.A O no hydrogen 3.061 N/A ALA 62.A N GLN 58.A O no hydrogen 2.819 N/A ILE 63.A N VAL 59.A O no hydrogen 3.131 N/A ARG 64.A N GLY 60.A O no hydrogen 2.637 N/A ARG 64.A NE LEU 104.A O no hydrogen 3.470 N/A SER 65.A N LEU 61.A O no hydrogen 2.861 N/A LYS 66.A N ALA 62.A O no hydrogen 2.959 N/A LYS 66.A NZ GLU 41.A OE2 no hydrogen 3.314 N/A LYS 66.A NZ ASP 69.A OD1 no hydrogen 3.561 N/A ILE 67.A N ARG 64.A O no hydrogen 3.288 N/A ALA 68.A N ARG 64.A O no hydrogen 3.119 N/A ASP 69.A N SER 65.A O no hydrogen 2.966 N/A SER 71.A N LYS 66.A O no hydrogen 3.141 N/A SER 71.A OG ASP 69.A OD1 no hydrogen 2.925 N/A VAL 72.A N LYS 66.A O no hydrogen 3.052 N/A ARG 74.A NH1 ARG 74.A O no hydrogen 2.656 N/A ARG 74.A NH1 ASP 110.A OD1 no hydrogen 3.251 N/A ARG 74.A NH1 ASP 110.A OD2 no hydrogen 3.102 N/A ARG 74.A NH2 TYR 108.A O no hydrogen 3.241 N/A ARG 74.A NH2 ASP 110.A OD1 no hydrogen 3.472 N/A ARG 74.A NH2 ASP 110.A OD2 no hydrogen 2.753 N/A ASP 76.A N LYS 73.A O no hydrogen 2.732 N/A ILE 77.A N ARG 74.A O no hydrogen 3.142 N/A PHE 78.A N HIS 45.A O no hydrogen 2.618 N/A TYR 79.A N ASP 110.A OD2 no hydrogen 2.557 N/A TYR 79.A OH GLU 56.A OE1 no hydrogen 2.699 N/A THR 80.A N ILE 47.A O no hydrogen 2.799 N/A SER 81.A N LEU 111.A O no hydrogen 3.033 N/A SER 81.A OG GLU 56.A OE1 no hydrogen 2.543 N/A LYS 82.A NZ ASP 48.A OD1 no hydrogen 3.529 N/A LYS 82.A NZ ASP 48.A OD2 no hydrogen 2.797 N/A LYS 82.A NZ SER 49.A O no hydrogen 2.961 N/A LYS 82.A NZ TYR 53.A OH no hydrogen 3.052 N/A LEU 83.A N LEU 113.A O no hydrogen 2.590 N/A TRP 84.A NE1 VAL 126.A O no hydrogen 2.647 N/A SER 85.A OG HIS 88.A NE2 no hydrogen 3.101 N/A SER 85.A OG PHE 116.A O no hydrogen 3.137 N/A SER 85.A OG VAL 118.A O no hydrogen 2.962 N/A ASN 86.A ND2 GLY 123.A O no hydrogen 3.022 N/A SER 87.A N TRP 84.A O no hydrogen 2.895 N/A SER 87.A OG ASN 86.A OD1 no hydrogen 3.333 N/A HIS 88.A NE2 SER 85.A OG no hydrogen 3.101 N/A ARG 89.A NE ASP 138.A OD2 no hydrogen 3.115 N/A ARG 89.A NH2 ASP 138.A OD1 no hydrogen 3.518 N/A LEU 92.A N ARG 89.A O no hydrogen 2.644 N/A VAL 93.A N PRO 90.A O no hydrogen 3.233 N/A ARG 94.A NE GLU 98.A OE2 no hydrogen 2.709 N/A ALA 96.A N LEU 92.A O no hydrogen 3.247 N/A LEU 97.A N VAL 93.A O no hydrogen 3.037 N/A GLU 98.A N ARG 94.A O no hydrogen 2.780 N/A ARG 99.A N PRO 95.A O no hydrogen 2.839 N/A ARG 99.A NH1 GLU 124.A OE2 no hydrogen 2.746 N/A ARG 99.A NH2 GLU 124.A OE1 no hydrogen 3.557 N/A ARG 99.A NH2 GLU 124.A OE2 no hydrogen 2.789 N/A SER 100.A N ALA 96.A O no hydrogen 3.046 N/A SER 100.A OG GLU 56.A OE1 no hydrogen 3.492 N/A SER 100.A OG GLU 56.A OE2 no hydrogen 2.752 N/A LEU 101.A N LEU 97.A O no hydrogen 2.906 N/A LYS 102.A N GLU 98.A O no hydrogen 2.893 N/A ASN 103.A N ARG 99.A O no hydrogen 3.063 N/A LEU 104.A N SER 100.A O no hydrogen 2.777 N/A GLN 105.A N LEU 101.A O no hydrogen 2.719 N/A GLN 105.A NE2 LYS 102.A O no hydrogen 2.719 N/A LEU 106.A N LEU 101.A O no hydrogen 3.453 N/A VAL 109.A N LEU 157.A O no hydrogen 2.970 N/A ASP 110.A N TYR 79.A O no hydrogen 2.999 N/A LEU 111.A N TYR 79.A O no hydrogen 3.322 N/A TYR 112.A N SER 160.A O no hydrogen 2.725 N/A LEU 113.A N SER 81.A O no hydrogen 3.052 N/A ILE 114.A N GLY 162.A O no hydrogen 3.079 N/A HIS 115.A N LEU 83.A O no hydrogen 2.972 N/A VAL 120.A N SER 85.A O no hydrogen 2.916 N/A LYS 121.A N LEU 136.A O no hydrogen 2.953 N/A LYS 121.A NZ ASP 138.A OD1 no hydrogen 2.776 N/A ASP 130.A N LYS 134.A O no hydrogen 2.668 N/A GLY 133.A N ASP 130.A O no hydrogen 3.011 N/A LEU 136.A N PRO 128.A O no hydrogen 3.283 N/A ASP 138.A N SER 119.A O no hydrogen 3.126 N/A ALA 144.A N ASP 141.A O no hydrogen 2.699 N/A THR 145.A N ASP 141.A O no hydrogen 3.030 N/A THR 145.A OG1 HIS 88.A O no hydrogen 2.742 N/A THR 145.A OG1 ASP 141.A O no hydrogen 3.436 N/A TRP 146.A N LEU 142.A O no hydrogen 2.578 N/A TRP 146.A NE1 GLU 150.A OE1 no hydrogen 3.124 N/A TRP 146.A NE1 TYR 182.A O no hydrogen 2.874 N/A GLU 147.A N ALA 144.A O no hydrogen 3.080 N/A ALA 148.A N ALA 144.A O no hydrogen 3.244 N/A ALA 148.A N THR 145.A O no hydrogen 2.962 N/A MET 149.A N THR 145.A O no hydrogen 3.141 N/A GLU 150.A N TRP 146.A O no hydrogen 3.116 N/A LYS 151.A N GLU 147.A O no hydrogen 3.168 N/A CYS 152.A N ALA 148.A O no hydrogen 3.059 N/A CYS 152.A N MET 149.A O no hydrogen 3.015 N/A CYS 152.A SG ALA 148.A O no hydrogen 3.267 N/A LYS 153.A N MET 149.A O no hydrogen 2.967 N/A LYS 153.A NZ ASP 10.A OD2 no hydrogen 3.390 N/A ASP 154.A N GLU 150.A O no hydrogen 2.936 N/A ALA 155.A N LYS 151.A O no hydrogen 2.868 N/A GLY 156.A N LYS 153.A O no hydrogen 3.284 N/A LEU 157.A N CYS 152.A O no hydrogen 3.255 N/A LYS 159.A N VAL 109.A O no hydrogen 2.919 N/A SER 160.A OG ASP 10.A OD1 no hydrogen 3.287 N/A SER 160.A OG ASP 10.A OD2 no hydrogen 2.590 N/A GLY 162.A N TYR 112.A O no hydrogen 2.896 N/A VAL 163.A N CYS 186.A O no hydrogen 2.838 N/A SER 164.A N ILE 114.A O no hydrogen 3.205 N/A SER 164.A OG GLN 188.A O no hydrogen 2.705 N/A ASN 165.A N GLN 188.A O no hydrogen 3.105 N/A ASN 165.A ND2 HIS 115.A O no hydrogen 2.778 N/A PHE 166.A N ASN 187.A OD1 no hydrogen 3.443 N/A HIS 168.A N GLU 320.A OE1 no hydrogen 3.376 N/A ARG 169.A NH1 PRO 313.A O no hydrogen 2.895 N/A ARG 169.A NH2 ASN 314.A OD1 no hydrogen 2.599 N/A LEU 171.A N ASN 167.A O no hydrogen 2.783 N/A GLU 172.A N HIS 168.A O no hydrogen 2.916 N/A MET 173.A N ARG 169.A O no hydrogen 2.959 N/A ILE 174.A N LEU 170.A O no hydrogen 3.224 N/A LEU 175.A N LEU 171.A O no hydrogen 3.023 N/A ASN 176.A N GLU 172.A O no hydrogen 2.765 N/A LYS 177.A N ILE 174.A O no hydrogen 3.050 N/A LYS 177.A NZ GLU 147.A OE2 no hydrogen 2.405 N/A LYS 177.A NZ PRO 178.A O no hydrogen 3.115 N/A LEU 180.A N LYS 177.A O no hydrogen 3.150 N/A LYS 181.A N GLU 150.A OE1 no hydrogen 2.720 N/A LYS 181.A NZ ASP 154.A OD1 no hydrogen 3.028 N/A LYS 181.A NZ ASP 154.A OD2 no hydrogen 2.479 N/A TYR 182.A N GLU 150.A OE1 no hydrogen 2.784 N/A TYR 182.A OH ASP 154.A OD1 no hydrogen 2.465 N/A LYS 183.A NZ LYS 207.A O no hydrogen 2.707 N/A VAL 185.A N ILE 161.A O no hydrogen 2.886 N/A ASN 187.A N VAL 210.A O no hydrogen 2.956 N/A ASN 187.A ND2 PHE 166.A O no hydrogen 2.952 N/A GLN 188.A N VAL 163.A O no hydrogen 2.931 N/A GLN 188.A NE2 ASP 48.A OD1 no hydrogen 3.173 N/A VAL 189.A N VAL 212.A O no hydrogen 2.983 N/A CYS 191.A N TYR 214.A O no hydrogen 3.067 N/A CYS 191.A SG PHE 195.A O no hydrogen 3.751 N/A HIS 192.A N PHE 195.A O no hydrogen 3.387 N/A HIS 192.A NE2 GLU 190.A OE2 no hydrogen 3.014 N/A TYR 194.A OH ASP 236.A OD1 no hydrogen 2.399 N/A PHE 195.A N HIS 192.A O no hydrogen 2.754 N/A ARG 198.A NH1 ASP 202.A OD2 no hydrogen 2.782 N/A LEU 201.A N GLN 197.A O no hydrogen 2.748 N/A ASP 202.A N ARG 198.A O no hydrogen 2.759 N/A PHE 203.A N LYS 199.A O no hydrogen 3.130 N/A CYS 204.A N LEU 200.A O no hydrogen 2.791 N/A CYS 204.A SG LEU 200.A O no hydrogen 3.230 N/A LYS 205.A N LEU 201.A O no hydrogen 2.712 N/A LYS 205.A NZ ARG 261.A O no hydrogen 2.993 N/A SER 206.A N ASP 202.A O no hydrogen 2.860 N/A SER 206.A OG ASP 202.A O no hydrogen 3.476 N/A SER 206.A OG PHE 203.A O no hydrogen 2.306 N/A LYS 207.A N CYS 204.A O no hydrogen 2.749 N/A ASP 208.A N LYS 205.A O no hydrogen 2.967 N/A ILE 209.A N CYS 204.A O no hydrogen 2.972 N/A VAL 210.A N VAL 185.A O no hydrogen 3.278 N/A VAL 212.A N ASN 187.A O no hydrogen 3.280 N/A ALA 213.A N VAL 264.A O no hydrogen 2.897 N/A TYR 214.A N VAL 189.A O no hydrogen 3.106 N/A TYR 214.A OH ASN 165.A OD1 no hydrogen 2.771 N/A GLY 218.A N SER 215.A O no hydrogen 2.930 N/A SER 219.A OG GLY 218.A O no hydrogen 2.606 N/A ARG 221.A N SER 219.A OG no hydrogen 3.010 N/A VAL 226.A N GLU 222.A O no hydrogen 2.781 N/A ASN 229.A N ASP 227.A OD1 no hydrogen 3.260 N/A SER 230.A N ASP 227.A O no hydrogen 2.908 N/A SER 230.A OG ASP 227.A O no hydrogen 2.847 N/A GLU 235.A N VAL 232.A O no hydrogen 3.030 N/A ASP 236.A N LEU 233.A O no hydrogen 2.886 N/A LEU 239.A N ASP 236.A OD2 no hydrogen 3.144 N/A CYS 240.A N ASP 236.A O no hydrogen 3.208 N/A ALA 241.A N PRO 237.A O no hydrogen 2.958 N/A LEU 242.A N VAL 238.A O no hydrogen 3.217 N/A ALA 243.A N LEU 239.A O no hydrogen 3.081 N/A LYS 244.A N CYS 240.A O no hydrogen 3.087 N/A LYS 245.A N ALA 241.A O no hydrogen 2.992 N/A HIS 246.A N LEU 242.A O no hydrogen 3.098 N/A HIS 246.A NE2 GLU 290.A OE1 no hydrogen 2.810 N/A HIS 246.A NE2 GLU 290.A OE2 no hydrogen 2.526 N/A LYS 247.A N LYS 244.A O no hydrogen 2.699 N/A ARG 248.A N ALA 243.A O no hydrogen 2.862 N/A THR 249.A OG1 GLN 277.A OE1 no hydrogen 2.708 N/A LEU 252.A N THR 249.A OG1 no hydrogen 3.247 N/A ILE 253.A N THR 249.A O no hydrogen 3.103 N/A ILE 253.A N PRO 250.A O no hydrogen 3.140 N/A ALA 254.A N PRO 250.A O no hydrogen 3.033 N/A LEU 255.A N ALA 251.A O no hydrogen 2.965 N/A ARG 256.A N LEU 252.A O no hydrogen 2.848 N/A ARG 256.A NH1 VAL 281.A O no hydrogen 2.715 N/A TYR 257.A N ILE 253.A O no hydrogen 2.771 N/A TYR 257.A OH ASP 295.A OD1 no hydrogen 2.620 N/A GLN 258.A N ALA 254.A O no hydrogen 3.417 N/A LEU 259.A N LEU 255.A O no hydrogen 3.121 N/A GLN 260.A N ARG 256.A O no hydrogen 3.177 N/A ARG 261.A N TYR 257.A O no hydrogen 3.219 N/A ARG 261.A N GLN 258.A O no hydrogen 2.939 N/A GLY 262.A N LEU 259.A O no hydrogen 2.964 N/A VAL 263.A N GLN 258.A O no hydrogen 3.192 N/A VAL 264.A N LEU 211.A O no hydrogen 3.278 N/A VAL 265.A N VAL 16.A O no hydrogen 2.945 N/A LEU 266.A N ALA 213.A O no hydrogen 3.193 N/A ALA 267.A N GLY 18.A O no hydrogen 2.942 N/A SER 269.A OG ASN 271.A O no hydrogen 3.314 N/A TYR 270.A OH THR 21.A O no hydrogen 2.621 N/A ILE 275.A N ASN 271.A O no hydrogen 2.868 N/A ARG 276.A N GLU 272.A O no hydrogen 2.958 N/A GLN 277.A N GLN 273.A O no hydrogen 3.030 N/A ASN 278.A N ARG 274.A O no hydrogen 2.874 N/A GLN 280.A N GLN 277.A O no hydrogen 3.021 N/A VAL 281.A N ASN 278.A O no hydrogen 3.323 N/A GLU 283.A N GLN 280.A O no hydrogen 2.589 N/A THR 287.A N GLU 290.A OE1 no hydrogen 2.792 N/A THR 287.A OG1 GLU 289.A OE1 no hydrogen 3.368 N/A SER 288.A OG GLU 289.A OE1 no hydrogen 2.919 N/A GLU 289.A N GLU 289.A OE1 no hydrogen 2.556 N/A MET 291.A N THR 287.A O no hydrogen 2.761 N/A LYS 292.A N SER 288.A O no hydrogen 2.875 N/A LYS 292.A NZ ASP 295.A OD2 no hydrogen 3.013 N/A ALA 293.A N GLU 289.A O no hydrogen 2.814 N/A ILE 294.A N GLU 290.A O no hydrogen 2.914 N/A ASP 295.A N MET 291.A O no hydrogen 3.340 N/A GLY 296.A N LYS 292.A O no hydrogen 3.013 N/A GLY 296.A N ALA 293.A O no hydrogen 3.200 N/A LEU 297.A N ILE 294.A O no hydrogen 3.100 N/A ASN 298.A N ASP 295.A O no hydrogen 3.382 N/A ARG 299.A N TYR 194.A O no hydrogen 3.306 N/A ARG 299.A NE LEU 297.A O no hydrogen 3.076 N/A TYR 303.A N GLU 190.A OE2 no hydrogen 2.475 N/A TYR 303.A OH PRO 231.A O no hydrogen 2.728 N/A LEU 304.A N GLU 190.A OE1 no hydrogen 2.964 N/A PHE 309.A N LEU 306.A O no hydrogen 3.230 N/A ALA 310.A N ASP 307.A O no hydrogen 2.701 N/A ASN 314.A ND2 PRO 117.A O no hydrogen 3.376 N/A TYR 315.A N PRO 312.A O no hydrogen 3.356 N/A TYR 315.A OH THR 305.A O no hydrogen 2.538 N/A SER 318.A N PRO 316.A O no hydrogen 3.252 N/A