Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 1t46_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): GLY 1.A N ALA 148.A O no hydrogen 3.052 N/A GLY 1.A N ASN 151.A OD1 no hydrogen 3.385 N/A ASN 2.A N ASN 151.A OD1 no hydrogen 2.902 N/A ASN 3.A ND2 GLU 213.A OE2 no hydrogen 2.755 N/A TYR 4.A N ASN 2.A OD1 no hydrogen 2.738 N/A VAL 5.A N ASN 2.A O no hydrogen 3.443 N/A THR 10.A N ASP 8.A OD1 no hydrogen 3.111 N/A THR 10.A OG1 ASP 8.A OD1 no hydrogen 2.620 N/A THR 10.A OG1 ASP 8.A OD2 no hydrogen 3.336 N/A GLN 11.A N ASP 8.A O no hydrogen 2.944 N/A GLN 11.A NE2 ASP 8.A OD2 no hydrogen 3.454 N/A GLN 11.A NE2 THR 10.A OG1 no hydrogen 3.283 N/A TYR 14.A OH GLU 19.A OE2 no hydrogen 2.743 N/A LYS 17.A N ASP 15.A OD1 no hydrogen 3.384 N/A TRP 18.A N ASP 15.A O no hydrogen 3.159 N/A TRP 18.A NE1 SER 81.A OG no hydrogen 2.788 N/A GLU 19.A N HIS 16.A O no hydrogen 3.024 N/A PHE 20.A N ALA 95.A O no hydrogen 2.794 N/A ARG 22.A NE ILE 98.A O no hydrogen 3.191 N/A ARG 22.A NH1 ILE 98.A O no hydrogen 2.822 N/A ARG 22.A NH1 PRO 101.A O no hydrogen 3.012 N/A ARG 22.A NH2 PRO 101.A O no hydrogen 2.796 N/A ARG 24.A N PRO 21.A O no hydrogen 3.010 N/A LEU 25.A N ARG 22.A O no hydrogen 3.154 N/A SER 26.A N THR 43.A O no hydrogen 2.900 N/A GLY 28.A N GLU 41.A O no hydrogen 2.622 N/A LEU 31.A N VAL 39.A O no hydrogen 2.708 N/A GLY 32.A N VAL 39.A O no hydrogen 3.261 N/A GLY 34.A N GLY 37.A O no hydrogen 2.724 N/A LYS 38.A N MET 60.A O no hydrogen 2.982 N/A VAL 39.A N GLY 32.A O no hydrogen 2.710 N/A VAL 40.A N VAL 58.A O no hydrogen 2.783 N/A GLU 41.A N LYS 29.A O no hydrogen 2.783 N/A ALA 42.A N VAL 56.A O no hydrogen 2.917 N/A THR 43.A N SER 26.A O no hydrogen 2.891 N/A ALA 44.A N MET 54.A O no hydrogen 2.793 N/A TYR 45.A N ARG 24.A O no hydrogen 2.947 N/A GLY 46.A N ALA 52.A O no hydrogen 3.273 N/A ALA 52.A N LYS 49.A O no hydrogen 3.228 N/A MET 54.A N ALA 44.A O no hydrogen 2.984 N/A VAL 56.A N ALA 42.A O no hydrogen 2.809 N/A ALA 57.A N THR 106.A O no hydrogen 2.917 N/A VAL 58.A N VAL 40.A O no hydrogen 2.798 N/A LYS 59.A N VAL 104.A O no hydrogen 2.804 N/A LYS 59.A NZ GLU 76.A OE1 no hydrogen 2.635 N/A LYS 59.A NZ GLU 76.A OE2 no hydrogen 2.938 N/A LYS 59.A NZ ASP 174.A O no hydrogen 3.027 N/A LYS 59.A NZ PHE 175.A O no hydrogen 3.143 N/A MET 60.A N LYS 38.A O no hydrogen 2.917 N/A LYS 62.A N PHE 36.A O no hydrogen 2.964 N/A LYS 62.A NZ GLY 34.A O no hydrogen 2.893 N/A ALA 65.A N LYS 62.A O no hydrogen 3.039 N/A HIS 66.A N GLU 69.A OE2 no hydrogen 2.749 N/A GLU 69.A N HIS 66.A O no hydrogen 2.923 N/A ARG 70.A N HIS 66.A O no hydrogen 3.093 N/A ARG 70.A NE THR 102.A OG1 no hydrogen 2.774 N/A ARG 70.A NH2 THR 97.A O no hydrogen 2.751 N/A GLU 71.A N LEU 67.A O no hydrogen 2.817 N/A ALA 72.A N THR 68.A O no hydrogen 3.091 N/A LEU 73.A N GLU 69.A O no hydrogen 2.902 N/A MET 74.A N ARG 70.A O no hydrogen 2.860 N/A SER 75.A N GLU 71.A O no hydrogen 2.783 N/A SER 75.A OG GLU 71.A O no hydrogen 3.103 N/A GLU 76.A N ALA 72.A O no hydrogen 2.879 N/A LEU 77.A N LEU 73.A O no hydrogen 2.910 N/A LYS 78.A N MET 74.A O no hydrogen 2.923 N/A LYS 78.A NZ LEU 12.A O no hydrogen 3.103 N/A VAL 79.A N SER 75.A O no hydrogen 2.873 N/A LEU 80.A N GLU 76.A O no hydrogen 2.944 N/A SER 81.A N LEU 77.A O no hydrogen 2.981 N/A TYR 82.A N LYS 78.A O no hydrogen 2.853 N/A TYR 82.A OH LYS 150.A O no hydrogen 2.644 N/A LEU 83.A N VAL 79.A O no hydrogen 2.832 N/A GLY 84.A N LEU 80.A O no hydrogen 3.033 N/A ASN 85.A ND2 LEU 92.A O no hydrogen 2.798 N/A ASN 88.A ND2.A GLN 139.A OE1 no hydrogen 2.853 N/A ASN 88.A ND2.A THR 170.A O no hydrogen 2.922 N/A VAL 90.A N ILE 172.A O no hydrogen 3.027 N/A ASN 91.A N GLU 107.A OE1 no hydrogen 2.768 N/A ASN 91.A ND2 HIS 86.A O no hydrogen 2.841 N/A ASN 91.A ND2 ILE 89.A O no hydrogen 2.919 N/A LEU 92.A N ASN 85.A OD1 no hydrogen 2.956 N/A LEU 93.A N ILE 105.A O no hydrogen 2.758 N/A GLY 94.A N ILE 105.A O no hydrogen 3.206 N/A ALA 95.A N TRP 18.A O no hydrogen 2.899 N/A CYS 96.A N LEU 103.A O no hydrogen 2.890 N/A CYS 96.A SG PHE 20.A O no hydrogen 3.328 N/A THR 97.A N GLU 19.A OE1 no hydrogen 2.776 N/A THR 97.A OG1 GLU 19.A OE1 no hydrogen 3.477 N/A THR 97.A OG1 GLU 19.A OE2 no hydrogen 2.714 N/A LEU 103.A N CYS 96.A O no hydrogen 2.769 N/A VAL 104.A N LYS 59.A O no hydrogen 2.809 N/A ILE 105.A N GLY 94.A O no hydrogen 2.811 N/A THR 106.A N ALA 57.A O no hydrogen 2.854 N/A THR 106.A OG1 GLU 107.A O no hydrogen 2.911 N/A GLU 107.A N ASN 91.A O no hydrogen 3.058 N/A TYR 111.A N LEU 164.A O no hydrogen 2.904 N/A GLY 112.A N CYS 109.A O no hydrogen 2.894 N/A LEU 114.A N ILE 162.A O no hydrogen 2.715 N/A LEU 115.A N ASP 113.A OD2.A no hydrogen 3.101 N/A ASN 116.A N ASP 113.A OD1.B no hydrogen 2.825 N/A ASN 116.A ND2 ASP 113.A OD2.B no hydrogen 2.292 N/A PHE 117.A N ASP 113.A O no hydrogen 3.017 N/A LEU 118.A N LEU 114.A O no hydrogen 2.828 N/A ARG 119.A N LEU 115.A O no hydrogen 3.060 N/A ARG 119.A NE GLY 230.A O no hydrogen 2.728 N/A ARG 119.A NH1 GLY 230.A O no hydrogen 3.007 N/A ARG 120.A N ASN 116.A O no hydrogen 2.904 N/A LYS 121.A N PHE 117.A O no hydrogen 2.896 N/A LYS 121.A NZ LEU 126.A O no hydrogen 3.021 N/A ARG 122.A NH2 SER 231.A OG no hydrogen 3.010 N/A SER 124.A OG LYS 121.A O no hydrogen 2.684 N/A PHE 125.A N ARG 122.A O no hydrogen 3.334 N/A LEU 128.A N SER 124.A OG no hydrogen 3.158 N/A ASP 129.A N ASP 132.A OD1 no hydrogen 2.851 N/A ASP 132.A N ASP 129.A OD1 no hydrogen 3.140 N/A LEU 133.A N ASP 129.A O no hydrogen 3.265 N/A LEU 134.A N LEU 130.A O no hydrogen 2.841 N/A SER 135.A N GLU 131.A O no hydrogen 2.765 N/A PHE 136.A N ASP 132.A O no hydrogen 2.869 N/A SER 137.A N LEU 133.A O no hydrogen 2.956 N/A SER 137.A OG.A LEU 134.A O no hydrogen 2.628 N/A SER 137.A OG.B LEU 133.A O no hydrogen 2.847 N/A TYR 138.A N LEU 134.A O no hydrogen 2.848 N/A GLN 139.A N SER 135.A O no hydrogen 2.867 N/A GLN 139.A NE2 SER 135.A O no hydrogen 3.540 N/A GLN 139.A NE2 SER 135.A OG no hydrogen 2.941 N/A GLN 139.A NE2 ARG 168.A O no hydrogen 3.071 N/A VAL 140.A N PHE 136.A O no hydrogen 2.964 N/A ALA 141.A N SER 137.A O no hydrogen 3.038 N/A LYS 142.A N TYR 138.A O no hydrogen 2.788 N/A GLY 143.A N GLN 139.A O no hydrogen 2.920 N/A MET 144.A N VAL 140.A O no hydrogen 2.888 N/A ALA 145.A N ALA 141.A O no hydrogen 2.815 N/A PHE 146.A N LYS 142.A O no hydrogen 3.068 N/A LEU 147.A N GLY 143.A O no hydrogen 2.973 N/A ALA 148.A N MET 144.A O no hydrogen 2.847 N/A SER 149.A N ALA 145.A O no hydrogen 2.876 N/A SER 149.A OG PHE 146.A O no hydrogen 2.692 N/A LYS 150.A N PHE 146.A O no hydrogen 2.989 N/A LYS 150.A N LEU 147.A O no hydrogen 3.065 N/A LYS 150.A NZ TYR 82.A O no hydrogen 3.058 N/A ASN 151.A N ALA 148.A O no hydrogen 2.892 N/A ASN 151.A ND2 ASN 2.A O no hydrogen 2.981 N/A ASN 151.A ND2 ASN 151.A O no hydrogen 3.106 N/A CYS 152.A N LEU 147.A O no hydrogen 2.903 N/A CYS 152.A SG.A LYS 150.A O no hydrogen 3.795 N/A CYS 152.A SG.B ILE 153.A O no hydrogen 4.005 N/A HIS 154.A N ASP 215.A OD1 no hydrogen 2.679 N/A HIS 154.A NE2 CYS 173.A O no hydrogen 2.732 N/A ARG 155.A N ASP 215.A OD2 no hydrogen 3.011 N/A ASP 156.A N HIS 154.A ND1 no hydrogen 3.015 N/A ALA 159.A N GLU 225.A OE2 no hydrogen 2.825 N/A ARG 160.A NE TYR 187.A OH no hydrogen 2.771 N/A ARG 160.A NH1 ASP 156.A OD2 no hydrogen 2.909 N/A ASN 161.A N ALA 158.A O no hydrogen 2.819 N/A ASN 161.A ND2 ASP 156.A O no hydrogen 2.792 N/A ILE 162.A N ALA 159.A O no hydrogen 3.065 N/A LEU 163.A N LYS 171.A O no hydrogen 2.762 N/A LEU 164.A N GLY 112.A O no hydrogen 2.827 N/A THR 165.A N ILE 169.A O no hydrogen 2.815 N/A HIS 166.A N THR 165.A OG1 no hydrogen 2.740 N/A ARG 168.A NH1 LEU 126.A O no hydrogen 2.984 N/A ARG 168.A NH2 ALA 127.A O no hydrogen 3.322 N/A ARG 168.A NH2 ASP 132.A OD2 no hydrogen 3.090 N/A ILE 169.A N THR 165.A O no hydrogen 3.242 N/A THR 170.A N GLN 139.A OE1 no hydrogen 2.914 N/A LYS 171.A N LEU 163.A O no hydrogen 2.764 N/A LYS 171.A NZ HIS 86.A O no hydrogen 3.099 N/A LYS 171.A NZ ILE 89.A O no hydrogen 3.203 N/A LYS 171.A NZ GLU 107.A OE1 no hydrogen 2.751 N/A LYS 171.A NZ GLU 107.A OE2 no hydrogen 3.510 N/A ILE 172.A N ASN 88.A O no hydrogen 2.938 N/A CYS 173.A N ASN 161.A O no hydrogen 2.815 N/A CYS 173.A SG ASN 161.A O no hydrogen 3.330 N/A PHE 175.A N ASN 161.A OD1 no hydrogen 3.056 N/A ALA 178.A N PHE 175.A O no hydrogen 2.812 N/A ARG 179.A N GLY 176.A O no hydrogen 3.252 N/A ARG 179.A NH1 ASN 161.A OD1 no hydrogen 2.898 N/A ARG 179.A NH2 ASN 161.A OD1 no hydrogen 3.370 N/A ASN 183.A N ASP 180.A O no hydrogen 3.088 N/A ASN 183.A ND2 ASP 180.A OD2 no hydrogen 2.956 N/A ASN 186.A N ASP 184.A OD1 no hydrogen 3.027 N/A ASN 186.A ND2 ASP 184.A OD1 no hydrogen 2.832 N/A TYR 187.A N ASP 184.A O no hydrogen 2.924 N/A TYR 187.A OH ASP 156.A OD1 no hydrogen 2.497 N/A TYR 187.A OH ASP 156.A OD2 no hydrogen 3.387 N/A VAL 188.A N LEU 195.A O no hydrogen 2.780 N/A LYS 190.A N ALA 193.A O no hydrogen 2.817 N/A LEU 195.A N VAL 188.A O no hydrogen 2.806 N/A VAL 197.A N LEU 195.A O no hydrogen 2.776 N/A LYS 198.A NZ PRO 233.A O no hydrogen 2.970 N/A LYS 198.A NZ TYR 234.A O no hydrogen 2.925 N/A LYS 198.A NZ MET 237.A O no hydrogen 2.874 N/A TRP 199.A N PRO 196.A O no hydrogen 2.939 N/A TRP 199.A NE1 GLU 225.A OE2 no hydrogen 2.796 N/A MET 200.A N VAL 197.A O no hydrogen 2.988 N/A GLU 203.A N GLU 203.A OE1 no hydrogen 2.830 N/A SER 204.A N ALA 201.A O no hydrogen 2.946 N/A SER 204.A OG VAL 209.A O no hydrogen 2.668 N/A ILE 205.A N ALA 201.A O no hydrogen 3.028 N/A PHE 206.A N PRO 202.A O no hydrogen 2.810 N/A ASN 207.A N GLU 203.A O no hydrogen 2.850 N/A CYS 208.A N SER 204.A O no hydrogen 3.009 N/A THR 211.A N SER 214.A OG no hydrogen 2.763 N/A THR 211.A OG1 GLU 213.A OE2 no hydrogen 3.338 N/A PHE 212.A N ASN 3.A OD1 no hydrogen 3.368 N/A GLU 213.A N GLU 213.A OE2 no hydrogen 2.865 N/A SER 214.A N THR 211.A OG1 no hydrogen 2.922 N/A SER 214.A OG THR 211.A O no hydrogen 2.955 N/A ASP 215.A N THR 211.A O no hydrogen 3.177 N/A VAL 216.A N PHE 212.A O no hydrogen 3.284 N/A TRP 217.A N GLU 213.A O no hydrogen 3.118 N/A SER 218.A N SER 214.A O no hydrogen 3.106 N/A SER 218.A OG TRP 199.A O no hydrogen 2.683 N/A SER 218.A OG SER 214.A O no hydrogen 3.357 N/A TYR 219.A N ASP 215.A O no hydrogen 2.902 N/A TYR 219.A OH SER 137.A O no hydrogen 2.681 N/A GLY 220.A N VAL 216.A O no hydrogen 3.037 N/A ILE 221.A N TRP 217.A O no hydrogen 3.175 N/A PHE 222.A N SER 218.A O no hydrogen 2.811 N/A LEU 223.A N TYR 219.A O no hydrogen 2.797 N/A TRP 224.A N GLY 220.A O no hydrogen 3.078 N/A TRP 224.A NE1 LEU 254.A O no hydrogen 3.063 N/A GLU 225.A N ILE 221.A O no hydrogen 2.897 N/A LEU 226.A N PHE 222.A O no hydrogen 2.766 N/A PHE 227.A N LEU 223.A O no hydrogen 2.941 N/A SER 228.A N TRP 224.A O no hydrogen 2.926 N/A SER 228.A OG.A TRP 224.A O no hydrogen 2.904 N/A SER 228.A OG.A GLU 225.A O no hydrogen 2.998 N/A SER 228.A OG.B TRP 224.A O no hydrogen 2.757 N/A LEU 229.A N LEU 226.A O no hydrogen 2.986 N/A GLY 230.A N GLU 225.A O no hydrogen 2.787 N/A SER 231.A N SER 228.A O no hydrogen 3.375 N/A SER 231.A N SER 228.A OG.A no hydrogen 3.257 N/A SER 231.A OG SER 228.A O no hydrogen 3.037 N/A PHE 243.A N ASP 240.A OD2 no hydrogen 3.066 N/A TYR 244.A N ASP 240.A O no hydrogen 3.286 N/A LYS 245.A N SER 241.A O no hydrogen 3.148 N/A MET 246.A N LYS 242.A O no hydrogen 2.826 N/A ILE 247.A N PHE 243.A O no hydrogen 2.942 N/A LYS 248.A N TYR 244.A O no hydrogen 2.991 N/A GLU 249.A N LYS 245.A O no hydrogen 2.767 N/A GLY 250.A N MET 246.A O no hydrogen 3.047 N/A GLY 250.A N ILE 247.A O no hydrogen 3.257 N/A PHE 251.A N MET 246.A O no hydrogen 2.852 N/A ARG 252.A NE TRP 271.A O no hydrogen 2.783 N/A ARG 252.A NH1 ILE 247.A O no hydrogen 3.047 N/A ARG 252.A NH1 PHE 251.A O no hydrogen 2.898 N/A ARG 252.A NH2 TRP 271.A O no hydrogen 3.101 N/A SER 255.A OG PRO 256.A O no hydrogen 2.821 N/A ALA 259.A N PRO 256.A O no hydrogen 3.287 N/A TYR 264.A N PRO 260.A O no hydrogen 3.113 N/A TYR 264.A OH MET 253.A O no hydrogen 2.661 N/A ASP 265.A N ALA 261.A O no hydrogen 2.864 N/A ILE 266.A N GLU 262.A O no hydrogen 2.996 N/A MET 267.A N MET 263.A O no hydrogen 3.016 N/A LYS 268.A N TYR 264.A O no hydrogen 2.906 N/A THR 269.A N ASP 265.A O no hydrogen 3.102 N/A THR 269.A OG1 ASP 265.A O no hydrogen 3.536 N/A THR 269.A OG1 ILE 266.A O no hydrogen 2.730 N/A CYS 270.A N ILE 266.A O no hydrogen 2.902 N/A CYS 270.A SG ILE 266.A O no hydrogen 3.336 N/A TRP 271.A N MET 267.A O no hydrogen 3.058 N/A TRP 271.A N LYS 268.A O no hydrogen 3.226 N/A ASP 272.A N THR 269.A O no hydrogen 3.237 N/A ASP 274.A N ASP 272.A OD2 no hydrogen 2.901 N/A LEU 276.A N ASP 274.A OD2 no hydrogen 2.974 N/A LYS 277.A N ASP 274.A O no hydrogen 2.947 N/A LYS 277.A NZ ASP 274.A OD1 no hydrogen 2.762 N/A ARG 278.A N PRO 275.A O no hydrogen 3.269 N/A ARG 278.A NE ASP 272.A O no hydrogen 2.745 N/A ARG 278.A NH1 GLU 203.A OE2 no hydrogen 2.690 N/A ARG 278.A NH1 GLU 213.A O no hydrogen 3.015 N/A ARG 278.A NH2 GLU 203.A OE1 no hydrogen 2.909 N/A ARG 278.A NH2 GLU 203.A OE2 no hydrogen 3.453 N/A ARG 278.A NH2 ASP 272.A O no hydrogen 2.954 N/A THR 280.A N GLN 283.A OE1 no hydrogen 2.870 N/A THR 280.A OG1 GLN 283.A OE1 no hydrogen 3.519 N/A GLN 283.A N THR 280.A OG1 no hydrogen 3.124 N/A ILE 284.A N THR 280.A O no hydrogen 2.973 N/A VAL 285.A N PHE 281.A O no hydrogen 2.847 N/A GLN 286.A N LYS 282.A O no hydrogen 3.366 N/A LEU 287.A N GLN 283.A O no hydrogen 3.088 N/A ILE 288.A N ILE 284.A O no hydrogen 2.923 N/A GLU 289.A N VAL 285.A O no hydrogen 2.919 N/A LYS 290.A N GLN 286.A O no hydrogen 3.181 N/A GLN 291.A N LEU 287.A O no hydrogen 3.133 N/A ILE 292.A N ILE 288.A O no hydrogen 2.823 N/A SER 293.A N GLU 289.A O no hydrogen 3.103 N/A GLU 294.A N LYS 290.A O no hydrogen 2.923 N/A SER 295.A N GLN 291.A O no hydrogen 2.872 N/A SER 295.A N ILE 292.A O no hydrogen 3.175 N/A SER 295.A OG GLN 291.A O no hydrogen 2.935 N/A THR 296.A OG1 GLU 131.A OE2 no hydrogen 3.064 N/A THR 296.A OG1 ILE 292.A O no hydrogen 2.726 N/A