Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 1tsd_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): GLN 3.A N GLN 3.A OE1 no hydrogen 2.711 N/A GLN 3.A NE2 ARG 35.A O no hydrogen 2.979 N/A TYR 4.A OH VAL 170.A O no hydrogen 2.607 N/A LEU 5.A N MET 1.A O no hydrogen 3.057 N/A GLU 6.A N LYS 2.A O no hydrogen 2.959 N/A LEU 7.A N GLN 3.A O no hydrogen 3.033 N/A MET 8.A N TYR 4.A O no hydrogen 2.969 N/A GLN 9.A N LEU 5.A O no hydrogen 3.150 N/A GLN 9.A NE2 GLN 9.A O no hydrogen 3.471 N/A GLN 9.A NE2 ASP 13.A OD1 no hydrogen 2.642 N/A GLN 9.A NE2 ASP 13.A OD2 no hydrogen 3.264 N/A LYS 10.A N GLU 6.A O no hydrogen 3.096 N/A LYS 10.A NZ HIS 32.A ND1 no hydrogen 3.211 N/A VAL 11.A N LEU 7.A O no hydrogen 3.061 N/A LEU 12.A N MET 8.A O no hydrogen 2.922 N/A ASP 13.A N GLN 9.A O no hydrogen 2.770 N/A GLU 14.A N LYS 10.A O no hydrogen 2.752 N/A GLY 15.A N VAL 11.A O no hydrogen 2.676 N/A THR 16.A N SER 28.A O no hydrogen 2.992 N/A THR 16.A OG1 GLN 17.A O no hydrogen 3.532 N/A LYS 18.A N THR 26.A O no hydrogen 2.835 N/A LYS 18.A NZ ASP 205.A OD2 no hydrogen 2.773 N/A ARG 21.A NH1 ILE 264.A O no hydrogen 2.807 N/A THR 22.A N ASP 20.A OD2 no hydrogen 3.032 N/A THR 22.A OG1 ASP 20.A OD2 no hydrogen 2.564 N/A THR 22.A OG1 THR 24.A OG1 no hydrogen 2.983 N/A GLY 23.A N ASP 20.A O no hydrogen 3.166 N/A THR 24.A OG1 THR 22.A OG1 no hydrogen 2.983 N/A GLY 25.A N ASP 20.A OD1 no hydrogen 2.817 N/A THR 26.A N LYS 18.A O no hydrogen 2.907 N/A THR 26.A OG1 LYS 18.A O no hydrogen 3.498 N/A LEU 27.A N LEU 208.A O no hydrogen 2.871 N/A SER 28.A N THR 16.A O no hydrogen 2.618 N/A SER 28.A OG ASP 205.A OD1 no hydrogen 3.172 N/A ILE 29.A N THR 206.A O no hydrogen 3.039 N/A GLY 31.A N GLY 204.A O no hydrogen 3.337 N/A HIS 32.A N GLY 203.A O no hydrogen 3.338 N/A GLN 33.A NE2 THR 202.A OG1 no hydrogen 3.135 N/A MET 34.A N TRP 201.A O no hydrogen 3.038 N/A ARG 35.A NH1 ASP 198.A OD2 no hydrogen 2.955 N/A PHE 36.A N PHE 199.A O no hydrogen 2.829 N/A ASN 37.A ND2 GLY 197.A O no hydrogen 3.686 N/A LEU 38.A N GLY 197.A O no hydrogen 2.933 N/A ASP 40.A N ASN 37.A O no hydrogen 2.860 N/A GLY 41.A N LEU 38.A O no hydrogen 3.288 N/A PHE 42.A N PRO 228.A O no hydrogen 3.002 N/A LEU 44.A N PHE 42.A O no hydrogen 2.945 N/A LYS 48.A NZ PHE 171.A O no hydrogen 3.008 N/A ARG 49.A NH2 PRO 254.A O no hydrogen 3.469 N/A CYS 50.A N TYR 252.A OH no hydrogen 3.026 N/A CYS 50.A SG VAL 45.A O no hydrogen 3.932 N/A ILE 56.A N LEU 52.A O no hydrogen 2.938 N/A HIS 57.A N ARG 53.A O no hydrogen 2.969 N/A HIS 57.A ND1 TYR 71.A OH no hydrogen 2.964 N/A GLU 58.A N SER 54.A O no hydrogen 3.060 N/A LEU 59.A N ILE 55.A O no hydrogen 3.237 N/A LEU 60.A N ILE 56.A O no hydrogen 3.012 N/A TRP 61.A N HIS 57.A O no hydrogen 3.333 N/A TRP 61.A NE1 ASN 68.A O no hydrogen 2.820 N/A PHE 62.A N GLU 58.A O no hydrogen 3.087 N/A LEU 63.A N LEU 59.A O no hydrogen 2.951 N/A GLN 64.A N LEU 60.A O no hydrogen 2.901 N/A GLN 64.A N TRP 61.A O no hydrogen 3.229 N/A GLY 65.A N PHE 62.A O no hydrogen 3.093 N/A ASP 66.A N TRP 61.A O no hydrogen 3.297 N/A ASN 68.A N ASP 66.A OD1 no hydrogen 3.008 N/A ASN 68.A ND2 ASN 87.A O no hydrogen 2.995 N/A ASN 68.A ND2 ASP 89.A OD1 no hydrogen 2.513 N/A ILE 69.A N GLY 88.A O no hydrogen 3.084 N/A ALA 70.A N ASN 68.A OD1 no hydrogen 3.112 N/A TYR 71.A OH HIS 57.A ND1 no hydrogen 2.964 N/A HIS 73.A N ILE 69.A O no hydrogen 2.869 N/A GLU 74.A N ALA 70.A O no hydrogen 2.934 N/A ASN 76.A N HIS 73.A O no hydrogen 2.652 N/A VAL 77.A N LEU 72.A O no hydrogen 2.589 N/A TRP 80.A NE1 GLU 58.A OE2 no hydrogen 2.893 N/A ASP 81.A N THR 78.A O no hydrogen 2.960 N/A TRP 83.A N TRP 80.A O no hydrogen 3.155 N/A ALA 84.A N ASP 81.A O no hydrogen 3.399 N/A ASP 85.A N ASP 89.A O no hydrogen 2.968 N/A ASN 87.A N ASP 85.A OD1 no hydrogen 2.815 N/A GLY 88.A N ASP 85.A O no hydrogen 3.001 N/A ASP 89.A N ASP 85.A OD1 no hydrogen 2.671 N/A LEU 90.A N THR 67.A O no hydrogen 3.081 N/A VAL 93.A N GLY 91.A O no hydrogen 2.822 N/A LYS 96.A NZ ALA 100.A O no hydrogen 2.695 N/A GLN 97.A N VAL 93.A O no hydrogen 3.311 N/A GLN 97.A NE2 ASN 134.A OD1 no hydrogen 2.877 N/A TRP 98.A N TYR 94.A O no hydrogen 2.760 N/A ARG 99.A N GLY 95.A O no hydrogen 3.124 N/A ARG 99.A NE ASP 110.A OD1 no hydrogen 3.070 N/A ARG 99.A NH1 LEU 63.A O no hydrogen 2.851 N/A ARG 99.A NH2 ASP 110.A OD2 no hydrogen 3.086 N/A ALA 100.A N LYS 96.A O no hydrogen 2.985 N/A TRP 101.A N ILE 109.A O no hydrogen 2.984 N/A THR 103.A N ARG 107.A O no hydrogen 2.863 N/A THR 103.A OG1 ASP 105.A OD1 no hydrogen 2.597 N/A THR 103.A OG1 ARG 107.A O no hydrogen 3.551 N/A ASP 105.A N THR 103.A OG1 no hydrogen 3.234 N/A ARG 107.A N THR 103.A OG1 no hydrogen 3.124 N/A ARG 107.A NE ASP 105.A OD1 no hydrogen 2.505 N/A ARG 107.A NH2 ASP 105.A OD1 no hydrogen 3.364 N/A HIS 108.A ND1 ALA 100.A O no hydrogen 3.366 N/A ILE 109.A N TRP 101.A O no hydrogen 2.824 N/A GLN 111.A N TRP 98.A O no hydrogen 2.873 N/A GLN 111.A NE2 GLN 97.A O no hydrogen 2.825 N/A GLN 111.A NE2 SER 131.A O no hydrogen 2.776 N/A THR 113.A N ASP 110.A OD1 no hydrogen 3.234 N/A THR 114.A N ASP 110.A O no hydrogen 3.074 N/A THR 114.A OG1 ASP 110.A O no hydrogen 2.722 N/A VAL 115.A N GLN 111.A O no hydrogen 2.948 N/A LEU 116.A N ILE 112.A O no hydrogen 3.020 N/A ASN 117.A N THR 113.A O no hydrogen 2.911 N/A GLN 118.A N THR 114.A O no hydrogen 3.049 N/A GLN 118.A NE2 THR 114.A O no hydrogen 3.649 N/A LEU 119.A N VAL 115.A O no hydrogen 3.012 N/A LYS 120.A N LEU 116.A O no hydrogen 3.186 N/A ASN 121.A N ASN 117.A O no hydrogen 2.805 N/A ASP 122.A N GLN 118.A O no hydrogen 2.659 N/A SER 125.A N ASP 122.A O no hydrogen 3.071 N/A ARG 127.A N SER 125.A OG no hydrogen 3.090 N/A VAL 130.A N PHE 150.A O no hydrogen 3.041 N/A SER 131.A N GLN 111.A OE1 no hydrogen 3.045 N/A ALA 132.A N ALA 148.A O no hydrogen 2.748 N/A TRP 133.A N SER 131.A OG no hydrogen 3.093 N/A ASN 134.A N ALA 132.A O no hydrogen 2.958 N/A GLU 137.A N ASN 134.A O no hydrogen 3.275 N/A LYS 140.A N GLU 137.A O no hydrogen 2.647 N/A LYS 140.A NZ GLU 137.A OE2 no hydrogen 3.367 N/A MET 141.A N LEU 138.A O no hydrogen 3.160 N/A ALA 142.A N LEU 90.A O no hydrogen 2.832 N/A CYS 146.A N TYR 94.A OH no hydrogen 2.883 N/A HIS 147.A ND1 TYR 181.A OH no hydrogen 2.581 N/A ALA 148.A N TYR 164.A O no hydrogen 3.147 N/A PHE 150.A N VAL 130.A O no hydrogen 2.906 N/A GLN 151.A N GLN 162.A O no hydrogen 2.877 N/A PHE 152.A N ILE 128.A O no hydrogen 2.805 N/A TYR 153.A N SER 160.A O no hydrogen 3.136 N/A ALA 155.A N LYS 158.A O no hydrogen 3.111 N/A LYS 158.A N ALA 155.A O no hydrogen 2.847 N/A LYS 158.A NZ GLN 39.A OE1 no hydrogen 3.309 N/A LEU 159.A N GLU 195.A O no hydrogen 2.745 N/A SER 160.A N TYR 153.A O no hydrogen 2.909 N/A SER 160.A OG ASP 198.A O no hydrogen 3.486 N/A CYS 161.A N ASP 198.A O no hydrogen 3.127 N/A CYS 161.A SG GLN 151.A O no hydrogen 3.851 N/A GLN 162.A N GLN 151.A O no hydrogen 2.935 N/A LEU 163.A N VAL 200.A O no hydrogen 2.989 N/A TYR 164.A N PHE 149.A O no hydrogen 2.972 N/A GLN 165.A N THR 202.A O no hydrogen 2.887 N/A GLN 165.A NE2 SER 167.A O no hydrogen 3.128 N/A GLN 165.A NE2 ASN 177.A OD1 no hydrogen 3.159 N/A ARG 166.A N CYS 146.A O no hydrogen 2.868 N/A ARG 166.A NE PRO 145.A O no hydrogen 2.945 N/A ARG 166.A NH2 ALA 144.A O no hydrogen 3.006 N/A CYS 168.A N ASP 205.A O no hydrogen 2.927 N/A VAL 170.A N HIS 207.A O no hydrogen 2.741 N/A LEU 172.A N ASP 169.A OD1 no hydrogen 3.228 N/A LEU 174.A N ASP 169.A O no hydrogen 3.170 N/A PHE 176.A N GLY 173.A O no hydrogen 2.902 N/A ASN 177.A N GLY 173.A O no hydrogen 3.116 N/A ILE 178.A N LEU 174.A O no hydrogen 2.830 N/A ALA 179.A N PRO 175.A O no hydrogen 3.384 N/A SER 180.A N PHE 176.A O no hydrogen 3.048 N/A TYR 181.A OH HIS 147.A ND1 no hydrogen 2.581 N/A ALA 182.A N ILE 178.A O no hydrogen 3.294 N/A LEU 183.A N ALA 179.A O no hydrogen 3.084 N/A LEU 184.A N SER 180.A O no hydrogen 3.190 N/A VAL 185.A N TYR 181.A O no hydrogen 3.005 N/A HIS 186.A N ALA 182.A O no hydrogen 3.276 N/A HIS 186.A ND1 ALA 182.A O no hydrogen 3.038 N/A MET 187.A N LEU 183.A O no hydrogen 3.029 N/A MET 188.A N LEU 184.A O no hydrogen 2.831 N/A ALA 189.A N VAL 185.A O no hydrogen 2.933 N/A GLN 190.A N HIS 186.A O no hydrogen 3.109 N/A GLN 190.A NE2 ARG 234.A O no hydrogen 3.320 N/A GLN 190.A NE2 TYR 242.A OH no hydrogen 2.505 N/A GLN 191.A N MET 187.A O no hydrogen 3.122 N/A GLN 191.A NE2 PRO 236.A O no hydrogen 3.550 N/A GLN 191.A NE2 TYR 242.A OH no hydrogen 2.792 N/A CYS 192.A N MET 188.A O no hydrogen 3.039 N/A CYS 192.A SG MET 188.A O no hydrogen 3.601 N/A LEU 194.A N ALA 189.A O no hydrogen 2.745 N/A GLU 195.A N GLY 157.A O no hydrogen 3.172 N/A GLY 197.A N LEU 159.A O no hydrogen 2.839 N/A ASP 198.A N SER 160.A OG no hydrogen 2.953 N/A PHE 199.A N PHE 36.A O no hydrogen 2.874 N/A VAL 200.A N CYS 161.A O no hydrogen 3.025 N/A TRP 201.A N MET 34.A O no hydrogen 2.708 N/A TRP 201.A NE1 GLN 165.A OE1 no hydrogen 2.776 N/A THR 202.A N LEU 163.A O no hydrogen 2.995 N/A THR 202.A OG1 GLN 162.A OE1 no hydrogen 2.760 N/A GLY 203.A N HIS 32.A O no hydrogen 2.979 N/A GLY 204.A N GLN 165.A O no hydrogen 2.849 N/A ASP 205.A N ARG 166.A O no hydrogen 2.946 N/A THR 206.A N ILE 29.A O no hydrogen 2.936 N/A THR 206.A OG1 GLY 204.A O no hydrogen 3.188 N/A HIS 207.A N CYS 168.A O no hydrogen 2.859 N/A LEU 208.A N LEU 27.A O no hydrogen 3.143 N/A SER 210.A N GLY 25.A O no hydrogen 2.990 N/A SER 210.A OG GLY 25.A O no hydrogen 3.029 N/A HIS 212.A N TYR 209.A O no hydrogen 3.015 N/A HIS 212.A NE2 PRO 261.A O no hydrogen 2.741 N/A GLN 215.A NE2 ASN 211.A O no hydrogen 3.602 N/A THR 216.A N HIS 212.A O no hydrogen 2.804 N/A HIS 217.A N MET 213.A O no hydrogen 3.031 N/A LEU 218.A N ASP 214.A O no hydrogen 3.151 N/A GLN 219.A N GLN 215.A O no hydrogen 3.064 N/A GLN 219.A NE2 THR 47.A OG1 no hydrogen 3.053 N/A LEU 220.A N THR 216.A O no hydrogen 3.257 N/A SER 221.A N LEU 218.A O no hydrogen 3.019 N/A SER 221.A OG LEU 218.A O no hydrogen 2.509 N/A ARG 222.A N GLN 219.A O no hydrogen 3.037 N/A ARG 222.A NH1 THR 47.A O no hydrogen 3.036 N/A ARG 222.A NH1 PRO 256.A O no hydrogen 2.595 N/A ARG 225.A N THR 46.A OG1 no hydrogen 2.818 N/A ARG 225.A NH1 ASP 253.A O no hydrogen 3.293 N/A LYS 229.A N GLU 250.A O no hydrogen 2.674 N/A ILE 231.A N GLU 248.A O no hydrogen 2.677 N/A LYS 233.A N ASP 246.A O no hydrogen 2.893 N/A LYS 233.A NZ GLU 245.A O no hydrogen 3.049 N/A ARG 234.A NE ASP 246.A OD1 no hydrogen 2.863 N/A ARG 234.A NH2 ASP 241.A O no hydrogen 3.016 N/A ARG 234.A NH2 ASP 246.A OD2 no hydrogen 2.818 N/A SER 238.A OG ASP 241.A OD1 no hydrogen 2.753 N/A PHE 240.A N SER 238.A OG no hydrogen 3.155 N/A ASP 241.A N SER 238.A O no hydrogen 3.038 N/A ARG 243.A N ASP 246.A OD2 no hydrogen 2.749 N/A GLU 245.A N GLU 245.A OE1 no hydrogen 2.893 N/A ASP 246.A N ARG 243.A O no hydrogen 3.052 N/A PHE 247.A N PHE 244.A O no hydrogen 3.462 N/A GLU 248.A N ILE 231.A O no hydrogen 2.820 N/A GLU 250.A N LYS 229.A O no hydrogen 2.735 N/A TYR 252.A OH VAL 45.A O no hydrogen 2.464 N/A HIS 255.A N THR 46.A O no hydrogen 2.677 N/A HIS 255.A NE2 GLU 223.A O no hydrogen 2.538 N/A