Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 1x8m_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ARG 5.A N TYR 40.A O no hydrogen 2.677 N/A ARG 5.A NE ASP 3.A OD2 no hydrogen 2.913 N/A ARG 5.A NH1 GLU 24.A O no hydrogen 3.105 N/A ARG 5.A NH1 LEU 26.A O no hydrogen 2.771 N/A ARG 5.A NH2 ASP 3.A OD1 no hydrogen 3.021 N/A ARG 5.A NH2 LEU 26.A O no hydrogen 3.034 N/A ALA 11.A N HIS 9.A ND1 no hydrogen 2.828 N/A HIS 12.A N HIS 9.A O no hydrogen 3.024 N/A ALA 13.A N HIS 9.A O no hydrogen 2.960 N/A LYS 14.A N SER 10.A O no hydrogen 2.990 N/A THR 15.A N HIS 12.A O no hydrogen 3.323 N/A THR 15.A OG1 HIS 12.A O no hydrogen 3.066 N/A LEU 16.A N ALA 13.A O no hydrogen 2.919 N/A GLY 20.A N ASP 17.A OD2 no hydrogen 2.594 N/A LEU 21.A N ASP 17.A O no hydrogen 2.863 N/A ARG 22.A N THR 18.A O no hydrogen 3.104 N/A ARG 22.A NH1 GLU 28.A OE2 no hydrogen 3.105 N/A ARG 22.A NH2 VAL 223.A O no hydrogen 2.836 N/A ASN 23.A N GLN 19.A O no hydrogen 2.907 N/A GLU 24.A N GLY 20.A O no hydrogen 3.259 N/A PHE 25.A N LEU 21.A O no hydrogen 3.021 N/A LEU 26.A N ARG 22.A O no hydrogen 2.914 N/A VAL 27.A N ALA 229.A O no hydrogen 2.780 N/A ASP 34.A N MET 52.A O no hydrogen 3.027 N/A GLU 35.A N VAL 32.A O no hydrogen 3.053 N/A THR 37.A N GLY 50.A O no hydrogen 2.808 N/A THR 37.A OG1 LYS 29.A O no hydrogen 3.143 N/A THR 37.A OG1 VAL 30.A O no hydrogen 3.132 N/A VAL 39.A N VAL 48.A O no hydrogen 2.636 N/A TYR 40.A N ASP 3.A O no hydrogen 2.767 N/A SER 41.A N ILE 46.A O no hydrogen 2.943 N/A HIS 42.A N ARG 5.A O no hydrogen 2.908 N/A ILE 43.A N SER 41.A OG no hydrogen 3.175 N/A ILE 47.A N CYS 131.A O no hydrogen 2.932 N/A VAL 48.A N VAL 39.A O no hydrogen 2.650 N/A GLY 49.A N TYR 129.A O no hydrogen 3.304 N/A ILE 51.A N PHE 127.A O no hydrogen 2.712 N/A ILE 54.A N ASP 34.A OD1 no hydrogen 2.710 N/A THR 55.A N ASP 34.A OD1 no hydrogen 2.865 N/A THR 55.A OG1 ASP 34.A OD2 no hydrogen 3.027 N/A LYS 56.A N ASP 34.A OD1 no hydrogen 3.205 N/A THR 57.A OG1 PHE 116.A O no hydrogen 3.216 N/A VAL 58.A N PHE 116.A O no hydrogen 2.853 N/A VAL 60.A N VAL 114.A O no hydrogen 3.068 N/A GLY 65.A N GLY 61.A O no hydrogen 3.068 N/A LYS 66.A N GLY 62.A O no hydrogen 3.110 N/A LEU 68.A N GLY 65.A O no hydrogen 2.944 N/A GLY 69.A N LYS 66.A O no hydrogen 2.847 N/A VAL 70.A N GLY 65.A O no hydrogen 2.858 N/A SER 71.A N GLU 75.A OE1 no hydrogen 2.494 N/A SER 71.A OG GLU 75.A OE1 no hydrogen 3.028 N/A PHE 73.A N GLY 61.A O no hydrogen 2.758 N/A GLU 75.A N TYR 72.A O no hydrogen 2.802 N/A ARG 77.A NH1 ARG 45.A O no hydrogen 3.198 N/A ARG 77.A NH2 ARG 45.A O no hydrogen 3.025 N/A GLU 78.A N ALA 132.A O no hydrogen 2.864 N/A LEU 79.A N VAL 107.A O no hydrogen 2.863 N/A GLY 80.A N ASN 130.A O no hydrogen 2.740 N/A VAL 81.A N LEU 105.A O no hydrogen 2.867 N/A ILE 82.A N TYR 128.A O no hydrogen 2.922 N/A ASN 83.A N ASP 103.A O no hydrogen 3.036 N/A ASN 83.A ND2 GLY 86.A O no hydrogen 2.756 N/A ASN 83.A ND2 ILE 99.A O no hydrogen 3.257 N/A ASN 83.A ND2 GLY 100.A O no hydrogen 3.245 N/A ILE 84.A N LYS 126.A O no hydrogen 2.705 N/A GLY 85.A N ASN 83.A OD1 no hydrogen 3.003 N/A GLY 86.A N PRO 124.A O no hydrogen 2.699 N/A GLY 88.A N ILE 99.A O no hydrogen 3.092 N/A THR 89.A N ALA 117.A O no hydrogen 2.545 N/A THR 89.A OG1 TYR 97.A O no hydrogen 3.321 N/A ILE 90.A N TYR 97.A O no hydrogen 2.953 N/A THR 91.A N VAL 115.A O no hydrogen 2.789 N/A VAL 92.A N GLN 95.A O no hydrogen 2.772 N/A ASP 93.A N GLU 113.A O no hydrogen 2.926 N/A GLN 95.A N VAL 92.A O no hydrogen 2.961 N/A CYS 96.A SG THR 89.A OG1 no hydrogen 3.329 N/A TYR 97.A N ILE 90.A O no hydrogen 2.950 N/A ILE 99.A N GLY 88.A O no hydrogen 3.151 N/A GLY 100.A N ASP 103.A OD1 no hydrogen 2.810 N/A ARG 102.A N ASN 83.A O no hydrogen 2.742 N/A ARG 102.A NH2 GLU 184.A OE1 no hydrogen 3.417 N/A ARG 102.A NH2 GLU 184.A OE2 no hydrogen 3.543 N/A ASP 103.A N GLY 100.A O no hydrogen 2.907 N/A ALA 104.A N VAL 143.A O no hydrogen 2.703 N/A LEU 105.A N VAL 81.A O no hydrogen 2.912 N/A TYR 106.A N LYS 141.A O no hydrogen 2.750 N/A TYR 106.A OH GLU 78.A OE2 no hydrogen 2.528 N/A VAL 107.A N LEU 79.A O no hydrogen 3.043 N/A LYS 109.A NZ HIS 135.A O no hydrogen 3.253 N/A GLY 110.A N LEU 74.A O no hydrogen 3.057 N/A ALA 111.A N GLY 108.A O no hydrogen 3.482 N/A LYS 112.A N ASP 93.A OD2 no hydrogen 2.890 N/A GLU 113.A N ASP 93.A OD1 no hydrogen 2.764 N/A VAL 114.A N VAL 60.A O no hydrogen 3.029 N/A VAL 115.A N THR 91.A O no hydrogen 2.875 N/A PHE 116.A N VAL 58.A O no hydrogen 2.625 N/A ALA 117.A N THR 89.A O no hydrogen 2.813 N/A SER 118.A OG PRO 53.A O no hydrogen 2.331 N/A ILE 119.A N ALA 87.A O no hydrogen 3.221 N/A THR 123.A N ASP 120.A O no hydrogen 3.192 N/A THR 123.A OG1 ASP 120.A OD2 no hydrogen 3.556 N/A ALA 125.A N SER 118.A OG no hydrogen 3.127 N/A LYS 126.A N ASN 83.A OD1 no hydrogen 2.975 N/A LYS 126.A NZ GLU 227.A OE2 no hydrogen 3.333 N/A PHE 127.A N ILE 51.A O no hydrogen 2.865 N/A TYR 128.A N ILE 82.A O no hydrogen 2.969 N/A TYR 129.A N GLY 49.A O no hydrogen 3.016 N/A TYR 129.A OH THR 37.A O no hydrogen 2.617 N/A ASN 130.A N GLY 80.A O no hydrogen 2.991 N/A CYS 131.A N ILE 47.A O no hydrogen 2.981 N/A CYS 131.A SG GLU 78.A O no hydrogen 3.438 N/A ALA 132.A N GLU 78.A O no hydrogen 3.068 N/A ALA 134.A N ARG 76.A O no hydrogen 2.925 N/A LYS 141.A N TYR 106.A O no hydrogen 2.797 N/A LYS 141.A NZ VAL 172.A O no hydrogen 2.870 N/A LYS 142.A NZ GLU 98.A O no hydrogen 2.650 N/A VAL 143.A N ALA 104.A O no hydrogen 2.847 N/A THR 144.A OG1 GLU 147.A OE2 no hydrogen 2.653 N/A VAL 148.A N PRO 145.A O no hydrogen 3.074 N/A VAL 151.A N ILE 164.A O no hydrogen 3.068 N/A THR 152.A OG1 THR 163.A OG1 no hydrogen 3.079 N/A LEU 153.A N ARG 162.A O no hydrogen 2.885 N/A THR 158.A OG1 ASP 155.A O no hydrogen 3.331 N/A SER 159.A N ASN 156.A O no hydrogen 3.242 N/A SER 159.A OG GLY 188.A O no hydrogen 3.502 N/A ASN 160.A N ASP 155.A O no hydrogen 3.126 N/A ARG 162.A N LEU 153.A O no hydrogen 2.961 N/A THR 163.A N GLU 184.A O no hydrogen 2.760 N/A THR 163.A OG1 THR 152.A OG1 no hydrogen 3.079 N/A ILE 164.A N VAL 151.A O no hydrogen 2.717 N/A ASN 165.A N LEU 182.A O no hydrogen 2.671 N/A TYR 167.A N MET 180.A O no hydrogen 3.279 N/A TYR 167.A OH ARG 102.A O no hydrogen 2.652 N/A PHE 168.A N MET 180.A O no hydrogen 3.127 N/A VAL 172.A N VAL 169.A O no hydrogen 2.870 N/A LEU 173.A N VAL 169.A O no hydrogen 3.156 N/A THR 175.A OG1 LEU 178.A O no hydrogen 2.732 N/A CYS 176.A N GLU 78.A OE2 no hydrogen 2.893 N/A CYS 176.A SG GLU 78.A OE2 no hydrogen 3.568 N/A CYS 176.A SG THR 136.A O no hydrogen 3.227 N/A GLN 177.A N GLU 78.A OE1 no hydrogen 2.748 N/A LEU 178.A N GLU 78.A OE1 no hydrogen 2.923 N/A SER 179.A N MET 252.A O no hydrogen 3.174 N/A MET 180.A N PHE 168.A O no hydrogen 3.151 N/A GLY 181.A N TRP 250.A O no hydrogen 2.892 N/A LEU 182.A N ASN 165.A O no hydrogen 2.810 N/A THR 183.A N PHE 248.A O no hydrogen 2.805 N/A GLU 184.A N THR 163.A O no hydrogen 2.882 N/A LEU 185.A N TYR 246.A O no hydrogen 3.175 N/A ALA 186.A N ARG 161.A O no hydrogen 2.770 N/A ASN 189.A N ALA 186.A O no hydrogen 2.952 N/A ASN 189.A ND2 ALA 186.A O no hydrogen 2.630 N/A ASN 189.A ND2 PRO 187.A O no hydrogen 3.436 N/A LEU 190.A N SER 159.A O no hydrogen 3.112 N/A LEU 190.A N SER 159.A OG no hydrogen 2.979 N/A TRP 191.A N SER 159.A O no hydrogen 3.163 N/A ASN 192.A N GLY 240.A O no hydrogen 3.316 N/A ARG 194.A NH1 GLU 196.A OE2 no hydrogen 2.759 N/A ARG 194.A NH2 VAL 258.A O no hydrogen 3.242 N/A MET 195.A N VAL 253.A O no hydrogen 3.316 N/A GLU 196.A N SER 232.A O no hydrogen 3.135 N/A VAL 197.A N GLY 251.A O no hydrogen 2.874 N/A TYR 198.A N VAL 230.A O no hydrogen 3.092 N/A PHE 199.A N ILE 249.A O no hydrogen 2.852 N/A TYR 200.A N GLN 228.A O no hydrogen 2.882 N/A PHE 201.A N THR 247.A O no hydrogen 3.104 N/A MET 203.A N ASN 226.A OD1 no hydrogen 3.077 N/A ALA 207.A N ASP 204.A O no hydrogen 3.191 N/A CYS 208.A SG THR 243.A OG1 no hydrogen 3.327 N/A VAL 209.A N MET 224.A O no hydrogen 2.701 N/A PHE 210.A N VAL 241.A O no hydrogen 2.664 N/A HIS 211.A N ILE 222.A O no hydrogen 3.071 N/A MET 212.A N SER 239.A O no hydrogen 2.612 N/A MET 213.A N ARG 220.A O no hydrogen 2.804 N/A GLY 214.A N SER 236.A OG no hydrogen 2.896 N/A GLU 218.A N GLN 215.A O no hydrogen 2.926 N/A ARG 220.A N MET 213.A O no hydrogen 2.774 N/A ILE 222.A N HIS 211.A O no hydrogen 2.840 N/A MET 224.A N VAL 209.A O no hydrogen 2.789 N/A HIS 225.A N GLN 228.A OE1 no hydrogen 2.681 N/A GLN 228.A N TYR 200.A O no hydrogen 3.237 N/A GLN 228.A NE2 GLU 28.A O no hydrogen 3.358 N/A ALA 229.A N VAL 27.A O no hydrogen 3.369 N/A VAL 230.A N TYR 198.A O no hydrogen 2.999 N/A ILE 231.A N PHE 25.A O no hydrogen 2.929 N/A SER 232.A N GLU 196.A O no hydrogen 2.795 N/A SER 232.A OG HIS 238.A ND1 no hydrogen 2.800 N/A TRP 235.A NE1 ILE 8.A O no hydrogen 3.182 N/A SER 236.A N PRO 233.A O no hydrogen 3.077 N/A SER 236.A OG ILE 237.A O no hydrogen 2.787 N/A ILE 237.A N GLY 214.A O no hydrogen 3.111 N/A HIS 238.A ND1 SER 232.A OG no hydrogen 2.800 N/A VAL 241.A N PHE 210.A O no hydrogen 2.929 N/A GLY 242.A N LEU 190.A O no hydrogen 2.849 N/A THR 243.A N CYS 208.A O no hydrogen 3.040 N/A THR 243.A OG1 CYS 208.A O no hydrogen 3.444 N/A LYS 244.A NZ ASP 206.A OD1 no hydrogen 3.327 N/A TYR 246.A OH GLY 240.A O no hydrogen 3.296 N/A THR 247.A N PHE 201.A O no hydrogen 3.504 N/A PHE 248.A N THR 183.A O no hydrogen 2.865 N/A ILE 249.A N PHE 199.A O no hydrogen 2.866 N/A TRP 250.A N GLY 181.A O no hydrogen 2.930 N/A GLY 251.A N VAL 197.A O no hydrogen 3.036 N/A MET 252.A N SER 179.A O no hydrogen 2.885 N/A VAL 253.A N MET 195.A O no hydrogen 3.401 N/A GLN 257.A NE2 THR 175.A O no hydrogen 3.261 N/A GLN 257.A NE2 LEU 178.A O no hydrogen 3.668 N/A