Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 2c5x_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): MET 1.A N GLU 2.A OE2 no hydrogen 3.359 N/A GLU 2.A N GLU 2.A OE2 no hydrogen 3.112 N/A PHE 4.A N MET 1.A O no hydrogen 3.036 N/A GLN 5.A N ARG 22.A O no hydrogen 2.906 N/A GLN 5.A NE2 LYS 6.A O no hydrogen 2.471 N/A LYS 6.A NZ TYR 77.A OH no hydrogen 3.315 N/A VAL 7.A N LYS 20.A O no hydrogen 2.643 N/A GLU 8.A N LYS 20.A O no hydrogen 3.104 N/A LYS 9.A NZ GLU 12.A OE2 no hydrogen 3.527 N/A ILE 10.A N VAL 18.A O no hydrogen 2.668 N/A GLY 13.A N GLY 16.A O no hydrogen 3.245 N/A THR 14.A OG1 ASP 145.A OD2 no hydrogen 3.532 N/A VAL 18.A N GLY 11.A O no hydrogen 2.770 N/A TYR 19.A N LEU 32.A O no hydrogen 2.740 N/A ALA 21.A N VAL 30.A O no hydrogen 2.878 N/A ARG 22.A N GLN 5.A O no hydrogen 2.890 N/A ASN 23.A N GLU 28.A O no hydrogen 3.014 N/A LYS 24.A N ASN 3.A O no hydrogen 2.456 N/A LYS 24.A NZ GLU 2.A O no hydrogen 3.190 N/A THR 26.A N ASN 23.A OD1 no hydrogen 2.349 N/A GLU 28.A N THR 26.A OG1 no hydrogen 3.105 N/A VAL 30.A N ALA 21.A O no hydrogen 2.648 N/A ALA 31.A N PHE 80.A O no hydrogen 3.119 N/A LEU 32.A N TYR 19.A O no hydrogen 2.733 N/A LYS 33.A N LEU 78.A O no hydrogen 2.743 N/A LYS 33.A NZ GLU 51.A OE1 no hydrogen 3.421 N/A LYS 34.A N VAL 17.A O no hydrogen 3.122 N/A ILE 35.A N LEU 76.A O no hydrogen 3.091 N/A GLU 40.A N ASP 38.A OD1 no hydrogen 2.522 N/A THR 41.A N ASP 38.A OD1 no hydrogen 2.211 N/A ILE 49.A N PRO 45.A O no hydrogen 2.957 N/A ARG 50.A N SER 46.A O no hydrogen 2.964 N/A GLU 51.A N THR 47.A O no hydrogen 2.624 N/A ILE 52.A N ALA 48.A O no hydrogen 3.021 N/A SER 53.A OG ILE 49.A O no hydrogen 2.490 N/A SER 53.A OG ARG 50.A O no hydrogen 3.352 N/A LEU 54.A N ARG 50.A O no hydrogen 2.973 N/A LEU 55.A N GLU 51.A O no hydrogen 2.861 N/A LYS 56.A N ILE 52.A O no hydrogen 2.903 N/A LYS 56.A NZ LYS 56.A O no hydrogen 1.797 N/A GLU 57.A N LEU 54.A O no hydrogen 2.675 N/A LEU 58.A N LEU 55.A O no hydrogen 3.045 N/A HIS 60.A NE2 ASN 62.A OD1 no hydrogen 3.092 N/A ASN 62.A ND2 ILE 141.A O no hydrogen 3.109 N/A ILE 63.A N HIS 60.A O no hydrogen 3.291 N/A VAL 64.A N LEU 143.A O no hydrogen 3.086 N/A LYS 65.A N GLU 81.A OE2 no hydrogen 3.184 N/A LEU 67.A N VAL 79.A O no hydrogen 2.450 N/A ILE 70.A N TYR 77.A O no hydrogen 2.711 N/A THR 72.A N LYS 75.A O no hydrogen 2.773 N/A THR 72.A OG1 LYS 75.A O no hydrogen 3.221 N/A TYR 77.A N ILE 70.A O no hydrogen 2.675 N/A LEU 78.A N LYS 33.A O no hydrogen 2.822 N/A VAL 79.A N ASP 68.A O no hydrogen 2.894 N/A PHE 80.A N ALA 31.A O no hydrogen 2.751 N/A GLU 81.A N LYS 65.A O no hydrogen 3.215 N/A HIS 84.A N ILE 135.A O no hydrogen 3.229 N/A GLN 85.A N ILE 135.A O no hydrogen 3.300 N/A LEU 87.A N PRO 130.A O no hydrogen 3.178 N/A LEU 87.A N LEU 133.A O no hydrogen 2.726 N/A LYS 88.A N PRO 130.A O no hydrogen 3.126 N/A LYS 88.A NZ ASP 92.A OD2 no hydrogen 2.485 N/A LYS 89.A N ASP 86.A OD1 no hydrogen 2.362 N/A LYS 89.A NZ ASP 86.A OD2 no hydrogen 3.358 N/A PHE 90.A N ASP 86.A O no hydrogen 2.632 N/A MET 91.A N LEU 87.A O no hydrogen 2.896 N/A MET 91.A N LYS 88.A O no hydrogen 2.715 N/A ASP 92.A N LYS 88.A O no hydrogen 3.243 N/A ALA 93.A N LYS 89.A O no hydrogen 2.670 N/A SER 94.A N MET 91.A O no hydrogen 3.278 N/A ALA 95.A N ASP 92.A O no hydrogen 3.401 N/A THR 97.A OG1 SER 94.A O no hydrogen 2.975 N/A GLY 98.A N SER 94.A O no hydrogen 2.814 N/A LEU 103.A N PRO 100.A O no hydrogen 2.691 N/A ILE 104.A N PRO 100.A O no hydrogen 3.081 N/A LYS 105.A N LEU 101.A O no hydrogen 2.864 N/A SER 106.A N PRO 102.A O no hydrogen 2.998 N/A TYR 107.A N LEU 103.A O no hydrogen 2.806 N/A LEU 108.A N ILE 104.A O no hydrogen 2.906 N/A PHE 109.A N LYS 105.A O no hydrogen 3.391 N/A GLN 110.A N SER 106.A O no hydrogen 2.879 N/A GLN 110.A NE2 SER 106.A O no hydrogen 3.687 N/A GLN 110.A NE2 SER 106.A OG no hydrogen 2.835 N/A GLN 110.A NE2 GLY 139.A O no hydrogen 3.237 N/A LEU 111.A N TYR 107.A O no hydrogen 2.796 N/A LEU 112.A N LEU 108.A O no hydrogen 2.774 N/A GLN 113.A N PHE 109.A O no hydrogen 2.987 N/A GLY 114.A N GLN 110.A O no hydrogen 2.787 N/A LEU 115.A N LEU 111.A O no hydrogen 2.817 N/A ALA 116.A N LEU 112.A O no hydrogen 2.702 N/A PHE 117.A N GLN 113.A O no hydrogen 3.118 N/A CYS 118.A N GLY 114.A O no hydrogen 2.888 N/A CYS 118.A SG GLY 114.A O no hydrogen 3.540 N/A HIS 119.A N LEU 115.A O no hydrogen 2.735 N/A HIS 119.A NE2 ASP 185.A OD2 no hydrogen 3.064 N/A SER 120.A N ALA 116.A O no hydrogen 3.094 N/A SER 120.A OG ALA 116.A O no hydrogen 3.204 N/A SER 120.A OG PHE 117.A O no hydrogen 2.790 N/A SER 120.A OG HIS 121.A ND1 no hydrogen 3.029 N/A HIS 121.A N PHE 117.A O no hydrogen 3.158 N/A HIS 121.A N CYS 118.A O no hydrogen 2.908 N/A HIS 121.A ND1 PHE 117.A O no hydrogen 3.020 N/A HIS 121.A ND1 SER 120.A OG no hydrogen 3.029 N/A ARG 122.A N HIS 119.A O no hydrogen 2.764 N/A ARG 122.A NH1 GLU 57.A OE1 no hydrogen 2.912 N/A ARG 122.A NH1 GLU 57.A OE2 no hydrogen 2.909 N/A ARG 122.A NH2 GLU 57.A OE1 no hydrogen 2.537 N/A ARG 122.A NH2 HIS 121.A O no hydrogen 2.934 N/A VAL 123.A N CYS 118.A O no hydrogen 3.323 N/A LEU 124.A N ARG 150.A O no hydrogen 2.869 N/A HIS 125.A N ASP 185.A OD2 no hydrogen 2.732 N/A HIS 125.A NE2 ALA 144.A O no hydrogen 3.168 N/A ARG 126.A N ASP 185.A OD1 no hydrogen 2.757 N/A ARG 126.A NE LEU 148.A O no hydrogen 2.957 N/A ARG 126.A NH2 TYR 159.A OH no hydrogen 2.759 N/A ASP 127.A N HIS 125.A ND1 no hydrogen 2.713 N/A LYS 129.A NZ ASP 127.A OD2 no hydrogen 3.367 N/A ASN 132.A N LYS 129.A O no hydrogen 2.287 N/A ASN 132.A ND2 ASP 127.A O no hydrogen 3.315 N/A LEU 133.A N PRO 130.A O no hydrogen 3.206 N/A LEU 134.A N LYS 142.A O no hydrogen 3.374 N/A ILE 135.A N GLN 85.A O no hydrogen 3.356 N/A ASN 136.A N ALA 140.A O no hydrogen 3.353 N/A GLY 139.A N ASN 136.A O no hydrogen 3.350 N/A ALA 140.A N ASN 136.A OD1 no hydrogen 2.945 N/A ILE 141.A N GLN 110.A OE1 no hydrogen 3.137 N/A LYS 142.A N LEU 134.A O no hydrogen 3.061 N/A LYS 142.A NZ PRO 61.A O no hydrogen 3.030 N/A LYS 142.A NZ GLU 81.A OE2 no hydrogen 2.931 N/A LEU 143.A N ASN 62.A O no hydrogen 2.512 N/A ALA 144.A N ASN 132.A O no hydrogen 3.169 N/A PHE 146.A N GLU 51.A OE2 no hydrogen 2.925 N/A GLY 147.A N ASP 145.A OD1 no hydrogen 3.310 N/A ALA 149.A N PHE 146.A O no hydrogen 3.137 N/A ARG 150.A N LEU 124.A O no hydrogen 3.005 N/A PHE 152.A N ARG 122.A O no hydrogen 2.661 N/A THR 158.A N LYS 178.A O no hydrogen 3.408 N/A THR 158.A OG1 CYS 177.A O no hydrogen 2.685 N/A GLU 162.A N TYR 159.A O no hydrogen 3.126 N/A TRP 167.A NE1 GLY 205.A O no hydrogen 2.949 N/A TYR 168.A OH GLU 195.A OE1 no hydrogen 2.199 N/A ARG 169.A NE THR 165.A O no hydrogen 2.892 N/A ARG 169.A NH2 THR 165.A O no hydrogen 2.566 N/A GLU 172.A N GLU 172.A OE2 no hydrogen 2.722 N/A ILE 173.A N ALA 170.A O no hydrogen 2.953 N/A LEU 174.A N ALA 170.A O no hydrogen 3.218 N/A LEU 175.A N GLU 172.A O no hydrogen 3.338 N/A GLY 176.A N GLU 172.A O no hydrogen 3.019 N/A CYS 177.A N GLU 172.A O no hydrogen 3.215 N/A CYS 177.A SG GLU 172.A O no hydrogen 2.918 N/A CYS 177.A SG TYR 179.A O no hydrogen 3.952 N/A TYR 180.A N VAL 156.A O no hydrogen 2.762 N/A VAL 184.A N SER 181.A O no hydrogen 3.223 N/A ASP 185.A N THR 182.A O no hydrogen 2.873 N/A TRP 187.A N ALA 183.A O no hydrogen 2.863 N/A SER 188.A N VAL 184.A O no hydrogen 3.042 N/A SER 188.A OG TYR 168.A O no hydrogen 2.888 N/A SER 188.A OG VAL 184.A O no hydrogen 3.109 N/A LEU 189.A N ASP 185.A O no hydrogen 3.091 N/A GLY 190.A N ILE 186.A O no hydrogen 2.829 N/A CYS 191.A N TRP 187.A O no hydrogen 3.144 N/A CYS 191.A SG TRP 187.A O no hydrogen 3.496 N/A ILE 192.A N SER 188.A O no hydrogen 2.971 N/A ILE 192.A N LEU 189.A O no hydrogen 2.792 N/A PHE 193.A N LEU 189.A O no hydrogen 2.841 N/A ALA 194.A N GLY 190.A O no hydrogen 3.049 N/A GLU 195.A N CYS 191.A O no hydrogen 3.157 N/A GLU 195.A N ILE 192.A O no hydrogen 2.507 N/A VAL 197.A N PHE 193.A O no hydrogen 2.665 N/A THR 198.A N GLU 195.A O no hydrogen 2.506 N/A THR 198.A OG1 ALA 194.A O no hydrogen 3.114 N/A THR 198.A OG1 ARG 200.A O no hydrogen 3.401 N/A ARG 199.A N GLU 195.A O no hydrogen 2.670 N/A GLY 205.A N PHE 203.A O no hydrogen 2.652 N/A GLY 205.A N GLN 211.A OE1 no hydrogen 2.614 N/A ASP 206.A N ASP 210.A OD2 no hydrogen 2.771 N/A ASP 210.A N SER 207.A OG no hydrogen 2.688 N/A GLN 211.A N SER 207.A O no hydrogen 2.925 N/A GLN 211.A NE2 PHE 203.A O no hydrogen 2.605 N/A LEU 212.A N GLU 208.A O no hydrogen 3.386 N/A PHE 213.A N ILE 209.A O no hydrogen 3.042 N/A ARG 214.A N ASP 210.A O no hydrogen 2.718 N/A ARG 214.A NE ASP 210.A OD2 no hydrogen 2.729 N/A ARG 214.A NH2 ASP 210.A OD2 no hydrogen 3.326 N/A ILE 215.A N GLN 211.A O no hydrogen 2.931 N/A PHE 216.A N LEU 212.A O no hydrogen 2.805 N/A ARG 217.A N PHE 213.A O no hydrogen 2.826 N/A THR 218.A N ILE 215.A O no hydrogen 2.492 N/A THR 218.A OG1 ARG 214.A O no hydrogen 3.256 N/A THR 221.A N TRP 243.A O no hydrogen 3.200 N/A THR 221.A OG1 PRO 241.A O no hydrogen 2.890 N/A VAL 226.A N ASP 223.A OD1 no hydrogen 2.345 N/A TRP 227.A N ASP 223.A O no hydrogen 3.136 N/A GLY 229.A N GLU 224.A OE1 no hydrogen 3.029 N/A VAL 230.A N TRP 227.A O no hydrogen 3.255 N/A THR 231.A N GLU 224.A OE2 no hydrogen 3.191 N/A THR 231.A OG1 GLU 224.A OE2 no hydrogen 2.070 N/A SER 232.A N GLY 229.A O no hydrogen 2.688 N/A SER 232.A OG GLY 229.A O no hydrogen 3.142 N/A MET 233.A N VAL 230.A O no hydrogen 2.712 N/A ASP 235.A N LEU 175.A O no hydrogen 2.890 N/A TYR 236.A N MET 233.A O no hydrogen 2.523 N/A PHE 240.A N LYS 237.A O no hydrogen 3.182 N/A TRP 243.A N THR 221.A OG1 no hydrogen 2.948 N/A GLN 246.A N THR 218.A O no hydrogen 3.387 N/A SER 249.A N ASP 247.A OD2 no hydrogen 2.924 N/A SER 249.A OG ASP 247.A OD2 no hydrogen 2.981 N/A LYS 250.A N ASP 247.A O no hydrogen 2.564 N/A VAL 252.A N PHE 248.A O no hydrogen 2.921 N/A LEU 255.A N VAL 252.A O no hydrogen 2.548 N/A GLY 259.A N ASP 256.A OD1 no hydrogen 3.054 N/A ARG 260.A N ASP 256.A O no hydrogen 3.210 N/A SER 261.A N GLU 257.A O no hydrogen 2.987 N/A LEU 262.A N ASP 258.A O no hydrogen 2.967 N/A LEU 263.A N GLY 259.A O no hydrogen 2.693 N/A SER 264.A N ARG 260.A O no hydrogen 2.896 N/A GLN 265.A N SER 261.A O no hydrogen 3.202 N/A GLN 265.A N LEU 262.A O no hydrogen 3.098 N/A MET 266.A N LEU 262.A O no hydrogen 3.006 N/A LEU 267.A N LEU 263.A O no hydrogen 2.965 N/A HIS 268.A N GLN 265.A O no hydrogen 3.457 N/A TYR 269.A OH GLY 220.A O no hydrogen 2.972 N/A ASN 272.A N ASP 270.A OD1 no hydrogen 2.694 N/A LYS 273.A N ASP 270.A O no hydrogen 2.692 N/A ARG 274.A N ASP 270.A O no hydrogen 2.964 N/A ARG 274.A N PRO 271.A O no hydrogen 3.391 N/A ARG 274.A NE HIS 268.A O no hydrogen 2.819 N/A ARG 274.A NH1 GLU 172.A OE1 no hydrogen 3.171 N/A ARG 274.A NH1 ALA 183.A O no hydrogen 3.144 N/A ARG 274.A NH2 GLU 172.A OE2 no hydrogen 3.006 N/A ARG 274.A NH2 HIS 268.A O no hydrogen 2.973 N/A ARG 274.A NH2 TYR 269.A O no hydrogen 2.933 N/A ILE 275.A N GLN 265.A O no hydrogen 3.406 N/A ALA 279.A N SER 276.A OG no hydrogen 2.682 N/A ALA 280.A N SER 276.A O no hydrogen 2.744 N/A LEU 281.A N ALA 277.A O no hydrogen 3.092 N/A LEU 281.A N LYS 278.A O no hydrogen 2.873 N/A ALA 282.A N ALA 279.A O no hydrogen 2.860 N/A HIS 283.A N ALA 280.A O no hydrogen 2.809 N/A PHE 285.A N HIS 283.A ND1 no hydrogen 2.940 N/A PHE 286.A N HIS 283.A O no hydrogen 2.648 N/A GLN 287.A N PRO 284.A O no hydrogen 3.187 N/A VAL 289.A N PHE 286.A O no hydrogen 2.880 N/A