Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 2clx_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ASN 3.A ND2 MET 1.A O no hydrogen 2.531 N/A GLN 5.A N ARG 22.A O no hydrogen 2.776 N/A VAL 7.A N LYS 20.A O no hydrogen 2.698 N/A GLU 8.A N LYS 20.A O no hydrogen 3.156 N/A LYS 9.A NZ GLU 12.A OE2 no hydrogen 3.179 N/A LYS 9.A NZ TYR 19.A OH no hydrogen 3.257 N/A ILE 10.A N VAL 18.A O no hydrogen 2.821 N/A TYR 15.A OH GLY 148.A O no hydrogen 2.640 N/A VAL 18.A N GLY 11.A O no hydrogen 2.823 N/A TYR 19.A N LEU 32.A O no hydrogen 2.929 N/A LYS 20.A N GLU 8.A O no hydrogen 2.696 N/A ALA 21.A N VAL 30.A O no hydrogen 2.965 N/A ARG 22.A N GLN 5.A O no hydrogen 2.679 N/A ASN 23.A N GLU 28.A O no hydrogen 2.801 N/A LYS 24.A N ASN 3.A O no hydrogen 2.594 N/A LYS 24.A NZ GLU 2.A O no hydrogen 2.798 N/A THR 26.A N ASN 23.A OD1 no hydrogen 2.830 N/A THR 26.A OG1 GLU 28.A OE2 no hydrogen 2.842 N/A GLY 27.A N ASN 23.A O no hydrogen 3.145 N/A GLU 28.A N THR 26.A OG1 no hydrogen 3.287 N/A VAL 30.A N ALA 21.A O no hydrogen 2.892 N/A ALA 31.A N PHE 75.A O no hydrogen 2.835 N/A LEU 32.A N TYR 19.A O no hydrogen 2.752 N/A LYS 33.A N LEU 73.A O no hydrogen 2.803 N/A LYS 33.A NZ GLY 16.A O no hydrogen 3.251 N/A LYS 34.A N VAL 17.A O no hydrogen 3.003 N/A ILE 35.A N LEU 71.A O no hydrogen 2.731 N/A ARG 36.A N TYR 15.A O no hydrogen 3.409 N/A ARG 36.A NE TYR 15.A O no hydrogen 2.579 N/A ARG 36.A NH2 THR 14.A O no hydrogen 2.768 N/A ALA 43.A N PRO 40.A O no hydrogen 2.989 N/A ILE 44.A N PRO 40.A O no hydrogen 3.202 N/A ARG 45.A N SER 41.A O no hydrogen 2.754 N/A GLU 46.A N THR 42.A O no hydrogen 2.780 N/A ILE 47.A N ALA 43.A O no hydrogen 2.770 N/A SER 48.A N ILE 44.A O no hydrogen 3.074 N/A SER 48.A OG ILE 44.A O no hydrogen 2.792 N/A LEU 49.A N ARG 45.A O no hydrogen 3.375 N/A LYS 51.A N SER 48.A O no hydrogen 2.974 N/A GLU 52.A N LEU 49.A O no hydrogen 3.155 N/A LEU 53.A N LEU 50.A O no hydrogen 3.071 N/A ASN 54.A ND2 LYS 51.A O no hydrogen 3.513 N/A ASN 57.A ND2 GLN 105.A OE1 no hydrogen 3.253 N/A ASN 57.A ND2 ILE 136.A O no hydrogen 2.922 N/A ILE 58.A N HIS 55.A O no hydrogen 3.009 N/A VAL 59.A N LEU 138.A O no hydrogen 2.851 N/A LYS 60.A N GLU 76.A OE2 no hydrogen 2.866 N/A LEU 62.A N VAL 74.A O no hydrogen 2.702 N/A ASP 63.A N VAL 74.A O no hydrogen 3.244 N/A ILE 65.A N TYR 72.A O no hydrogen 2.861 N/A THR 67.A N LYS 70.A O no hydrogen 2.978 N/A TYR 72.A N ILE 65.A O no hydrogen 3.016 N/A LEU 73.A N LYS 33.A O no hydrogen 2.917 N/A VAL 74.A N ASP 63.A O no hydrogen 2.834 N/A PHE 75.A N ALA 31.A O no hydrogen 2.716 N/A GLU 76.A N LYS 60.A O no hydrogen 2.955 N/A LEU 82.A N LEU 128.A O no hydrogen 2.754 N/A LYS 83.A NZ ASP 87.A OD2 no hydrogen 2.839 N/A LYS 84.A N ASP 81.A OD1 no hydrogen 2.652 N/A PHE 85.A N ASP 81.A O no hydrogen 3.067 N/A MET 86.A N LEU 82.A O no hydrogen 2.704 N/A ASP 87.A N LYS 83.A O no hydrogen 2.913 N/A ALA 88.A N LYS 84.A O no hydrogen 2.821 N/A SER 89.A N MET 86.A O no hydrogen 3.027 N/A SER 89.A OG PHE 85.A O no hydrogen 2.918 N/A ALA 90.A N ASP 87.A O no hydrogen 3.131 N/A GLY 93.A N SER 89.A O no hydrogen 2.569 N/A ILE 99.A N PRO 95.A O no hydrogen 3.000 N/A LYS 100.A N LEU 96.A O no hydrogen 2.753 N/A LYS 100.A NZ PHE 280.A O no hydrogen 2.809 N/A LYS 100.A NZ ASP 283.A OD1 no hydrogen 2.475 N/A LYS 100.A NZ ASP 283.A OD2 no hydrogen 3.538 N/A SER 101.A N PRO 97.A O no hydrogen 2.998 N/A SER 101.A OG THR 285.A O no hydrogen 3.303 N/A TYR 102.A N LEU 98.A O no hydrogen 2.880 N/A LEU 103.A N ILE 99.A O no hydrogen 2.938 N/A PHE 104.A N LYS 100.A O no hydrogen 2.999 N/A GLN 105.A N SER 101.A O no hydrogen 2.939 N/A GLN 105.A NE2 SER 101.A O no hydrogen 3.461 N/A GLN 105.A NE2 SER 101.A OG no hydrogen 3.071 N/A GLN 105.A NE2 GLY 134.A O no hydrogen 2.852 N/A LEU 106.A N TYR 102.A O no hydrogen 2.922 N/A LEU 107.A N LEU 103.A O no hydrogen 2.910 N/A GLN 108.A N PHE 104.A O no hydrogen 3.012 N/A GLN 108.A NE2 PHE 104.A O no hydrogen 3.593 N/A GLY 109.A N GLN 105.A O no hydrogen 2.944 N/A LEU 110.A N LEU 106.A O no hydrogen 2.797 N/A ALA 111.A N LEU 107.A O no hydrogen 2.785 N/A PHE 112.A N GLN 108.A O no hydrogen 3.042 N/A CYS 113.A N GLY 109.A O no hydrogen 3.061 N/A CYS 113.A SG GLY 109.A O no hydrogen 3.701 N/A HIS 114.A N LEU 110.A O no hydrogen 2.758 N/A SER 115.A N ALA 111.A O no hydrogen 2.951 N/A SER 115.A N PHE 112.A O no hydrogen 3.111 N/A SER 115.A OG ALA 111.A O no hydrogen 3.491 N/A SER 115.A OG PHE 112.A O no hydrogen 2.642 N/A HIS 116.A N PHE 112.A O no hydrogen 3.347 N/A HIS 116.A N CYS 113.A O no hydrogen 3.059 N/A HIS 116.A ND1 PHE 112.A O no hydrogen 3.204 N/A ARG 117.A N HIS 114.A O no hydrogen 2.841 N/A VAL 118.A N CYS 113.A O no hydrogen 2.898 N/A HIS 120.A N ASP 180.A OD2 no hydrogen 2.742 N/A ARG 121.A N ASP 180.A OD1 no hydrogen 2.774 N/A ARG 121.A NE TYR 175.A OH no hydrogen 3.166 N/A LYS 124.A N ASN 127.A OD1 no hydrogen 3.059 N/A LYS 124.A NZ ASP 122.A OD1 no hydrogen 2.619 N/A ASN 127.A N LYS 124.A O no hydrogen 2.889 N/A ASN 127.A ND2 ASP 122.A O no hydrogen 2.929 N/A LEU 128.A N PRO 125.A O no hydrogen 3.178 N/A LEU 129.A N LYS 137.A O no hydrogen 2.827 N/A ILE 130.A N GLN 80.A O no hydrogen 2.843 N/A ASN 131.A N ALA 135.A O no hydrogen 3.305 N/A THR 132.A OG1 GLU 133.A OE2 no hydrogen 3.242 N/A ALA 135.A N ASN 131.A OD1 no hydrogen 3.108 N/A ILE 136.A N GLN 105.A OE1 no hydrogen 3.017 N/A LYS 137.A N LEU 129.A O no hydrogen 2.841 N/A LYS 137.A NZ GLU 76.A OE1 no hydrogen 2.792 N/A LYS 137.A NZ GLU 76.A OE2 no hydrogen 3.247 N/A LEU 138.A N ASN 57.A O no hydrogen 2.956 N/A ALA 139.A N ASN 127.A O no hydrogen 2.813 N/A LEU 143.A N ASP 140.A O no hydrogen 3.270 N/A ALA 146.A N GLY 142.A O no hydrogen 3.207 N/A PHE 147.A N LEU 143.A O no hydrogen 2.965 N/A THR 153.A N GLU 157.A O no hydrogen 2.923 N/A THR 153.A OG1 GLU 157.A O no hydrogen 3.438 N/A THR 153.A OG1 GLU 157.A OE1 no hydrogen 2.661 N/A TYR 154.A N THR 14.A O no hydrogen 3.244 N/A THR 155.A N THR 153.A OG1 no hydrogen 3.066 N/A THR 155.A OG1 THR 153.A OG1 no hydrogen 3.305 N/A HIS 156.A N THR 153.A O no hydrogen 2.755 N/A GLU 157.A N THR 155.A OG1 no hydrogen 3.071 N/A VAL 159.A N VAL 151.A O no hydrogen 2.934 N/A TRP 162.A N THR 160.A OG1 no hydrogen 3.404 N/A TYR 163.A OH GLU 190.A OE1 no hydrogen 2.567 N/A ARG 164.A N LEU 161.A O no hydrogen 3.132 N/A GLU 167.A N GLU 167.A OE1 no hydrogen 2.780 N/A ILE 168.A N ALA 165.A O no hydrogen 3.132 N/A LEU 169.A N ALA 165.A O no hydrogen 3.323 N/A LEU 170.A N PRO 166.A O no hydrogen 2.778 N/A GLY 171.A N ILE 168.A O no hydrogen 2.942 N/A CYS 172.A N GLU 167.A O no hydrogen 2.937 N/A ALA 178.A N SER 176.A OG no hydrogen 3.028 N/A VAL 179.A N SER 176.A O no hydrogen 3.046 N/A ASP 180.A N THR 177.A O no hydrogen 3.024 N/A TRP 182.A N ALA 178.A O no hydrogen 3.120 N/A SER 183.A N VAL 179.A O no hydrogen 3.170 N/A SER 183.A OG TYR 163.A O no hydrogen 2.711 N/A SER 183.A OG VAL 179.A O no hydrogen 3.291 N/A LEU 184.A N ASP 180.A O no hydrogen 2.936 N/A GLY 185.A N ILE 181.A O no hydrogen 2.849 N/A CYS 186.A N TRP 182.A O no hydrogen 3.000 N/A CYS 186.A SG TRP 182.A O no hydrogen 3.512 N/A ILE 187.A N SER 183.A O no hydrogen 3.117 N/A PHE 188.A N LEU 184.A O no hydrogen 2.868 N/A ALA 189.A N GLY 185.A O no hydrogen 3.076 N/A GLU 190.A N CYS 186.A O no hydrogen 3.009 N/A MET 191.A N ILE 187.A O no hydrogen 2.888 N/A VAL 192.A N PHE 188.A O no hydrogen 3.102 N/A THR 193.A N ALA 189.A O no hydrogen 2.992 N/A THR 193.A OG1 ALA 189.A O no hydrogen 3.111 N/A ARG 194.A N GLU 190.A O no hydrogen 2.811 N/A ARG 194.A NH1 ALA 90.A O no hydrogen 3.222 N/A ARG 195.A N THR 193.A OG1 no hydrogen 3.314 N/A GLY 200.A N PHE 198.A O no hydrogen 2.946 N/A GLY 200.A N GLN 206.A OE1 no hydrogen 2.738 N/A ASP 201.A N ASP 205.A OD2 no hydrogen 3.139 N/A ASP 205.A N SER 202.A OG no hydrogen 3.052 N/A GLN 206.A N SER 202.A O no hydrogen 2.795 N/A GLN 206.A NE2 TRP 162.A O no hydrogen 3.134 N/A GLN 206.A NE2 PHE 198.A O no hydrogen 2.918 N/A LEU 207.A N GLU 203.A O no hydrogen 3.050 N/A PHE 208.A N ILE 204.A O no hydrogen 2.827 N/A ARG 209.A N ASP 205.A O no hydrogen 2.898 N/A ARG 209.A NE ASP 205.A OD2 no hydrogen 2.955 N/A ILE 210.A N GLN 206.A O no hydrogen 3.036 N/A PHE 211.A N LEU 207.A O no hydrogen 2.941 N/A ARG 212.A N PHE 208.A O no hydrogen 2.858 N/A THR 213.A N ILE 210.A O no hydrogen 3.090 N/A THR 213.A OG1 ARG 209.A O no hydrogen 3.475 N/A LEU 214.A N ILE 210.A O no hydrogen 2.802 N/A GLY 215.A N PHE 211.A O no hydrogen 2.729 N/A THR 216.A N TRP 238.A O no hydrogen 3.116 N/A THR 216.A OG1 PRO 236.A O no hydrogen 2.606 N/A VAL 220.A N ASP 218.A OD1 no hydrogen 3.132 N/A VAL 221.A N ASP 218.A OD1 no hydrogen 2.985 N/A TRP 222.A N ASP 218.A O no hydrogen 2.834 N/A GLY 224.A N GLU 219.A OE1 no hydrogen 2.929 N/A VAL 225.A N TRP 222.A O no hydrogen 2.914 N/A THR 226.A N GLU 219.A OE2 no hydrogen 3.089 N/A THR 226.A OG1 GLU 219.A OE2 no hydrogen 2.534 N/A SER 227.A N GLY 224.A O no hydrogen 3.148 N/A MET 228.A N VAL 225.A O no hydrogen 2.948 N/A ASP 230.A N LEU 170.A O no hydrogen 2.836 N/A TYR 231.A N MET 228.A O no hydrogen 3.063 N/A PHE 235.A N LYS 232.A O no hydrogen 2.911 N/A LYS 237.A NZ TYR 231.A OH no hydrogen 3.087 N/A TRP 238.A N THR 216.A OG1 no hydrogen 2.805 N/A ARG 240.A NH1 LEU 214.A O no hydrogen 3.121 N/A GLN 241.A N THR 213.A O no hydrogen 2.941 N/A LYS 245.A N ASP 242.A O no hydrogen 2.888 N/A VAL 246.A N PHE 243.A O no hydrogen 2.798 N/A VAL 247.A N PHE 243.A O no hydrogen 2.895 N/A LEU 250.A N VAL 247.A O no hydrogen 2.764 N/A GLY 254.A N ASP 251.A OD1 no hydrogen 2.958 N/A ARG 255.A N ASP 251.A O no hydrogen 2.929 N/A ARG 255.A NE LEU 250.A O no hydrogen 2.888 N/A SER 256.A N GLU 252.A O no hydrogen 2.916 N/A SER 256.A OG GLN 260.A OE1 no hydrogen 3.261 N/A SER 256.A OG HIS 278.A NE2 no hydrogen 3.036 N/A LEU 257.A N ASP 253.A O no hydrogen 2.852 N/A LEU 258.A N GLY 254.A O no hydrogen 2.837 N/A SER 259.A N ARG 255.A O no hydrogen 2.919 N/A SER 259.A OG.B SER 256.A O no hydrogen 2.849 N/A GLN 260.A N SER 256.A O no hydrogen 3.151 N/A MET 261.A N LEU 257.A O no hydrogen 3.081 N/A MET 261.A N LEU 258.A O no hydrogen 3.130 N/A LEU 262.A N SER 259.A O no hydrogen 3.164 N/A TYR 264.A OH GLY 215.A O no hydrogen 2.569 N/A ASN 267.A N ASP 265.A OD1 no hydrogen 3.030 N/A LYS 268.A N ASP 265.A O no hydrogen 2.841 N/A LYS 268.A NZ VAL 221.A O no hydrogen 3.507 N/A LYS 268.A NZ ASP 265.A OD2 no hydrogen 2.466 N/A ARG 269.A N ASP 265.A O no hydrogen 2.965 N/A ARG 269.A NE HIS 263.A O no hydrogen 2.847 N/A ARG 269.A NH1 GLU 167.A OE1 no hydrogen 3.482 N/A ARG 269.A NH1 GLU 167.A OE2 no hydrogen 2.873 N/A ARG 269.A NH1 ALA 178.A O no hydrogen 2.849 N/A ARG 269.A NH2 GLU 167.A OE1 no hydrogen 2.883 N/A ARG 269.A NH2 HIS 263.A O no hydrogen 3.068 N/A ARG 269.A NH2 TYR 264.A O no hydrogen 2.965 N/A ILE 270.A N GLN 260.A O no hydrogen 2.944 N/A ALA 274.A N SER 271.A OG no hydrogen 2.955 N/A ALA 275.A N SER 271.A O no hydrogen 2.952 N/A LEU 276.A N ALA 272.A O no hydrogen 3.024 N/A ALA 277.A N ALA 274.A O no hydrogen 3.066 N/A HIS 278.A N ALA 275.A O no hydrogen 2.933 N/A HIS 278.A NE2 SER 256.A OG no hydrogen 3.036 N/A PHE 280.A N HIS 278.A ND1 no hydrogen 2.936 N/A PHE 281.A N HIS 278.A O no hydrogen 3.014 N/A GLN 282.A N PRO 279.A O no hydrogen 3.087 N/A VAL 284.A N PHE 281.A O no hydrogen 3.046 N/A LYS 286.A NZ GLU 133.A O no hydrogen 2.583 N/A LEU 291.A N HIS 290.A ND1 no hydrogen 3.174 N/A