Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 2f6x_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): MET 1.A N GLU 117.A OE2 no hydrogen 2.957 N/A ARG 2.A NE TYR 77.A OH no hydrogen 3.480 N/A ARG 4.A N.A MET 1.A O no hydrogen 3.145 N/A ARG 4.A N.B MET 1.A O no hydrogen 3.146 N/A ARG 4.A NH1.A GLU 117.A OE2 no hydrogen 2.489 N/A ARG 4.A NH2.A GLU 117.A OE1 no hydrogen 3.454 N/A ARG 4.A NH2.A GLU 117.A OE2 no hydrogen 3.094 N/A ARG 4.A NH2.B LYS 187.A O no hydrogen 2.822 N/A LYS 5.A N.A ARG 2.A O no hydrogen 2.976 N/A LYS 5.A N.B ARG 2.A O no hydrogen 2.929 N/A TRP 6.A N TRP 3.A O no hydrogen 3.084 N/A ARG 7.A N ASP 32.A OD2 no hydrogen 2.716 N/A ARG 7.A NE ASP 210.A O no hydrogen 2.883 N/A ARG 7.A NH2 LEU 206.A O no hydrogen 2.890 N/A ARG 7.A NH2 ALA 209.A O no hydrogen 3.002 N/A HIS 8.A N ASP 32.A OD2 no hydrogen 2.838 N/A HIS 8.A ND1 THR 31.A OG1 no hydrogen 2.647 N/A HIS 8.A NE2 THR 229.A OG1 no hydrogen 3.087 N/A ILE 9.A N ILE 212.A O no hydrogen 2.997 N/A THR 10.A N ALA 33.A O no hydrogen 2.850 N/A THR 10.A OG1 THR 31.A OG1 no hydrogen 2.853 N/A LYS 11.A N VAL 214.A O no hydrogen 2.848 N/A LYS 11.A NZ GLU 64.A OE1 no hydrogen 2.534 N/A LYS 11.A NZ TYR 165.A OH no hydrogen 3.128 N/A LEU 12.A N MET 35.A O no hydrogen 2.985 N/A ASP 13.A N TYR 219.A OH no hydrogen 2.933 N/A ASP 15.A N ASP 13.A OD1 no hydrogen 2.789 N/A ARG 16.A N ASP 13.A O no hydrogen 3.125 N/A ARG 16.A NH1 ASN 216.A OD1 no hydrogen 2.982 N/A ASN 18.A ND2 ASP 13.A O no hydrogen 2.797 N/A THR 19.A OG1 GLU 21.A OE2 no hydrogen 3.564 N/A GLU 21.A N GLU 21.A OE2 no hydrogen 2.731 N/A ILE 22.A N THR 19.A OG1 no hydrogen 3.157 N/A ILE 23.A N THR 19.A O no hydrogen 2.940 N/A LYS 24.A N ASP 20.A O no hydrogen 2.931 N/A LYS 24.A NZ ASP 28.A OD2 no hydrogen 3.104 N/A ALA 25.A N GLU 21.A O no hydrogen 3.038 N/A VAL 26.A N ILE 22.A O no hydrogen 2.890 N/A ALA 27.A N ILE 23.A O no hydrogen 3.088 N/A ASP 28.A N LYS 24.A O no hydrogen 2.904 N/A SER 29.A N VAL 26.A O no hydrogen 3.052 N/A SER 29.A OG VAL 26.A O no hydrogen 2.561 N/A THR 31.A N SER 29.A OG no hydrogen 3.224 N/A THR 31.A OG1 HIS 8.A ND1 no hydrogen 2.647 N/A THR 31.A OG1 HIS 8.A O no hydrogen 3.193 N/A THR 31.A OG1 THR 10.A OG1 no hydrogen 2.853 N/A ASP 32.A N HIS 8.A O no hydrogen 2.825 N/A VAL 34.A N PRO 60.A O no hydrogen 3.098 N/A MET 35.A N THR 10.A O no hydrogen 2.805 N/A ILE 36.A N VAL 62.A O no hydrogen 2.745 N/A SER 37.A N LEU 12.A O no hydrogen 3.122 N/A SER 37.A OG GLU 64.A OE1 no hydrogen 2.739 N/A THR 39.A OG1 GLN 40.A O no hydrogen 3.108 N/A ASN 41.A N ASP 67.A OD1 no hydrogen 2.874 N/A VAL 42.A N THR 39.A O no hydrogen 3.259 N/A LYS 46.A N THR 43.A OG1 no hydrogen 3.053 N/A LYS 46.A NZ ASP 15.A OD2 no hydrogen 3.400 N/A ALA 47.A N THR 43.A O no hydrogen 2.891 N/A ARG 48.A N TYR 44.A O no hydrogen 2.809 N/A THR 49.A N GLU 45.A O no hydrogen 3.093 N/A THR 49.A OG1 GLU 45.A O no hydrogen 2.866 N/A LEU 50.A N LYS 46.A O no hydrogen 3.389 N/A ILE 51.A N ALA 47.A O no hydrogen 2.851 N/A GLU 52.A N ARG 48.A O no hydrogen 2.764 N/A LYS 53.A N THR 49.A O no hydrogen 3.232 N/A VAL 54.A N LEU 50.A O no hydrogen 2.930 N/A SER 55.A N ILE 51.A O no hydrogen 2.708 N/A SER 55.A OG ILE 51.A O no hydrogen 2.814 N/A GLN 56.A N LYS 53.A O no hydrogen 3.345 N/A GLN 56.A NE2 GLU 52.A O no hydrogen 3.354 N/A TYR 57.A N VAL 54.A O no hydrogen 2.916 N/A ILE 61.A N ASP 76.A OD2 no hydrogen 2.798 N/A VAL 62.A N VAL 34.A O no hydrogen 2.831 N/A VAL 63.A N TYR 77.A O no hydrogen 2.877 N/A GLU 64.A N ILE 36.A O no hydrogen 2.961 N/A SER 66.A OG THR 39.A O no hydrogen 2.863 N/A VAL 71.A N SER 69.A OG no hydrogen 3.377 N/A ASP 76.A N ILE 61.A O no hydrogen 2.926 N/A TYR 77.A N ILE 61.A O no hydrogen 3.281 N/A LEU 78.A N PHE 118.A O no hydrogen 2.902 N/A PHE 79.A N VAL 63.A O no hydrogen 3.059 N/A VAL 80.A N GLN 120.A O no hydrogen 2.869 N/A THR 82.A N GLU 122.A O no hydrogen 2.898 N/A THR 82.A OG1 ILE 92.A O no hydrogen 2.758 N/A VAL 83.A N TRP 91.A O no hydrogen 2.914 N/A LEU 84.A N TYR 124.A O no hydrogen 2.845 N/A ASN 85.A ND2 VAL 126.A O no hydrogen 2.967 N/A ASN 85.A ND2 LEU 140.A O no hydrogen 3.069 N/A SER 86.A N VAL 83.A O no hydrogen 3.098 N/A SER 86.A OG ASP 88.A O no hydrogen 3.051 N/A SER 86.A OG THR 137.A O no hydrogen 2.617 N/A ALA 87.A N LYS 138.A O no hydrogen 2.984 N/A ASP 88.A N SER 86.A OG no hydrogen 2.995 N/A ASP 90.A N ASP 88.A OD1 no hydrogen 2.904 N/A TRP 91.A N ASP 88.A O no hydrogen 2.970 N/A ILE 92.A N GLY 89.A O no hydrogen 3.002 N/A THR 93.A N GLY 89.A O no hydrogen 2.893 N/A GLY 94.A N GLY 89.A O no hydrogen 2.967 N/A LYS 95.A N ASP 90.A O no hydrogen 2.831 N/A LYS 95.A NZ ASP 90.A OD2 no hydrogen 3.474 N/A ALA 97.A N THR 93.A O no hydrogen 2.869 N/A GLN 98.A N GLY 94.A O no hydrogen 3.102 N/A GLN 98.A NE2 GLY 94.A O no hydrogen 3.351 N/A TRP 99.A N LYS 95.A O no hydrogen 2.967 N/A VAL 100.A N HIS 96.A O no hydrogen 3.043 N/A ARG 101.A N ALA 97.A O no hydrogen 2.851 N/A ARG 101.A NH1 ARG 101.A O no hydrogen 3.093 N/A MET 102.A N GLN 98.A O no hydrogen 3.029 N/A HIS 103.A N VAL 100.A O no hydrogen 2.856 N/A HIS 103.A NE2 SER 69.A O no hydrogen 3.258 N/A TYR 104.A N ARG 101.A O no hydrogen 3.242 N/A ASN 106.A N HIS 103.A O no hydrogen 2.957 N/A LYS 109.A N ASN 106.A OD1 no hydrogen 3.168 N/A PHE 110.A N ASN 106.A O no hydrogen 3.236 N/A THR 111.A N LEU 107.A O no hydrogen 2.657 N/A THR 111.A OG1 LEU 107.A O no hydrogen 2.883 N/A GLU 112.A N GLN 108.A O no hydrogen 3.119 N/A ILE 113.A N LYS 109.A O no hydrogen 3.166 N/A ILE 114.A N PHE 110.A O no hydrogen 3.016 N/A GLU 115.A N THR 111.A O no hydrogen 2.996 N/A SER 116.A N GLU 112.A O no hydrogen 3.072 N/A SER 116.A N ILE 113.A O no hydrogen 3.137 N/A SER 116.A OG ILE 113.A O no hydrogen 2.580 N/A PHE 118.A N SER 116.A OG no hydrogen 3.225 N/A GLN 120.A N LEU 78.A O no hydrogen 3.217 N/A GLN 120.A NE2 GLU 117.A O no hydrogen 2.926 N/A GLN 120.A NE2 GLU 117.A OE1 no hydrogen 2.892 N/A GLU 122.A N VAL 80.A O no hydrogen 2.724 N/A GLY 123.A N ILE 163.A O no hydrogen 2.742 N/A TYR 124.A N THR 82.A O no hydrogen 2.890 N/A TYR 124.A OH GLU 64.A OE1 no hydrogen 3.348 N/A TYR 124.A OH GLU 64.A OE2 no hydrogen 2.664 N/A ILE 125.A N TYR 165.A O no hydrogen 2.892 N/A VAL 126.A N ASN 85.A OD1 no hydrogen 2.977 N/A LEU 127.A N GLU 167.A O no hydrogen 2.856 N/A ASN 128.A ND2 TYR 168.A O no hydrogen 3.226 N/A ASN 128.A ND2 SER 169.A O no hydrogen 3.020 N/A ASP 130.A N.A ASN 128.A OD1 no hydrogen 3.187 N/A ASP 130.A N.B ASN 128.A OD1 no hydrogen 3.222 N/A SER 131.A N ASN 128.A O no hydrogen 3.013 N/A SER 131.A OG ASN 128.A O no hydrogen 2.503 N/A ALA 134.A N SER 131.A OG no hydrogen 3.095 N/A ARG 135.A N SER 131.A O no hydrogen 3.153 N/A ARG 135.A NH1 ASP 130.A O.B no hydrogen 3.151 N/A VAL 136.A N ALA 132.A O no hydrogen 2.756 N/A THR 137.A N VAL 133.A O no hydrogen 2.902 N/A THR 137.A OG1 VAL 133.A O no hydrogen 2.681 N/A LYS 138.A N ARG 135.A O no hydrogen 3.299 N/A LYS 138.A NZ VAL 136.A O no hydrogen 3.172 N/A ALA 139.A N ALA 134.A O no hydrogen 3.021 N/A LEU 140.A N ASN 85.A O no hydrogen 2.824 N/A CYS 141.A SG VAL 126.A O no hydrogen 3.531 N/A CYS 141.A SG ALA 139.A O no hydrogen 3.798 N/A ILE 143.A N CYS 141.A O no hydrogen 3.059 N/A LYS 145.A NZ GLU 146.A OE2 no hydrogen 3.086 N/A LEU 147.A N ASP 144.A OD1 no hydrogen 2.941 N/A ALA 148.A N ASP 144.A O no hydrogen 2.979 N/A ALA 149.A N LYS 145.A O no hydrogen 2.879 N/A SER 150.A N GLU 146.A O no hydrogen 2.900 N/A SER 150.A OG GLU 146.A O no hydrogen 2.898 N/A TYR 151.A N LEU 147.A O no hydrogen 2.845 N/A ALA 152.A N ALA 148.A O no hydrogen 2.986 N/A LEU 153.A N ALA 149.A O no hydrogen 2.955 N/A VAL 154.A N SER 150.A O no hydrogen 3.001 N/A GLY 155.A N TYR 151.A O no hydrogen 2.997 N/A GLU 156.A N ALA 152.A O no hydrogen 2.997 N/A LYS 157.A N LEU 153.A O no hydrogen 2.805 N/A LYS 157.A NZ GLU 156.A OE2 no hydrogen 2.941 N/A LEU 158.A N VAL 154.A O no hydrogen 3.037 N/A PHE 159.A N VAL 154.A O no hydrogen 3.181 N/A ASN 160.A ND2 GLU 156.A O no hydrogen 3.259 N/A LEU 161.A N GLY 155.A O no hydrogen 2.925 N/A ILE 164.A N ARG 189.A O no hydrogen 2.947 N/A TYR 165.A N GLY 123.A O no hydrogen 2.774 N/A ILE 166.A N PHE 191.A O no hydrogen 2.913 N/A GLU 167.A N ILE 125.A O no hydrogen 2.861 N/A TYR 168.A N GLY 193.A O no hydrogen 2.882 N/A SER 169.A N GLU 167.A OE2 no hydrogen 2.799 N/A THR 171.A N TYR 168.A O no hydrogen 2.971 N/A TYR 172.A OH LYS 201.A O no hydrogen 3.397 N/A TYR 172.A OH GLU 204.A OE1 no hydrogen 2.623 N/A GLY 173.A N TYR 192.A OH no hydrogen 2.848 N/A ASN 174.A N TYR 168.A OH no hydrogen 3.374 N/A GLU 176.A N ASN 174.A OD1 no hydrogen 2.795 N/A LEU 177.A N ASN 174.A O no hydrogen 2.864 N/A VAL 178.A N ASN 174.A O no hydrogen 3.094 N/A ALA 179.A N PRO 175.A O no hydrogen 2.932 N/A GLU 180.A N GLU 176.A O no hydrogen 2.988 N/A VAL 181.A N LEU 177.A O no hydrogen 3.092 N/A LYS 182.A N VAL 178.A O no hydrogen 3.061 N/A LYS 182.A NZ TYR 208.A O no hydrogen 2.680 N/A LYS 182.A NZ ASP 210.A OD1 no hydrogen 2.718 N/A LYS 183.A N ALA 179.A O no hydrogen 3.025 N/A LYS 183.A NZ GLU 180.A OE1 no hydrogen 3.389 N/A VAL 184.A N VAL 181.A O no hydrogen 3.232 N/A LEU 185.A N VAL 181.A O no hydrogen 3.288 N/A LEU 185.A N LYS 182.A O no hydrogen 3.289 N/A ASP 186.A N GLU 156.A OE1 no hydrogen 2.961 N/A LYS 187.A N GLU 156.A OE2 no hydrogen 3.419 N/A ALA 188.A N GLU 156.A OE1 no hydrogen 3.004 N/A ARG 189.A N PRO 162.A O no hydrogen 2.915 N/A ARG 189.A NH2 TRP 6.A O no hydrogen 3.026 N/A LEU 190.A N ASP 210.A OD2 no hydrogen 2.799 N/A PHE 191.A N ILE 164.A O no hydrogen 2.785 N/A TYR 192.A N THR 211.A O no hydrogen 2.895 N/A TYR 192.A OH GLY 194.A O no hydrogen 2.666 N/A GLY 193.A N ILE 166.A O no hydrogen 2.999 N/A ARG 199.A N GLU 228.A OE2.B no hydrogen 2.987 N/A ARG 199.A NH2 GLU 228.A OE1.A no hydrogen 2.490 N/A LYS 201.A N SER 198.A OG no hydrogen 3.197 N/A ALA 202.A N SER 198.A O no hydrogen 3.033 N/A ARG 203.A N ARG 199.A O no hydrogen 2.951 N/A GLU 204.A N GLU 200.A O.A no hydrogen 3.082 N/A GLU 204.A N GLU 200.A O.B no hydrogen 3.109 N/A MET 205.A N LYS 201.A O no hydrogen 3.033 N/A LEU 206.A N ALA 202.A O no hydrogen 2.944 N/A ARG 207.A N GLU 204.A O no hydrogen 3.129 N/A TYR 208.A N MET 205.A O no hydrogen 3.097 N/A ALA 209.A N MET 205.A O no hydrogen 2.782 N/A ASP 210.A N LEU 190.A O no hydrogen 2.807 N/A THR 211.A N LEU 190.A O no hydrogen 3.095 N/A THR 211.A OG1 TRP 6.A O no hydrogen 2.742 N/A ILE 212.A N ARG 7.A O no hydrogen 2.960 N/A ILE 213.A N TYR 192.A O no hydrogen 2.679 N/A VAL 214.A N ILE 9.A O no hydrogen 2.985 N/A ILE 218.A N GLY 215.A O no hydrogen 3.188 N/A TYR 219.A OH ASN 18.A OD1 no hydrogen 2.511 N/A GLU 220.A N ASN 216.A O no hydrogen 2.823 N/A LYS 221.A N VAL 217.A O no hydrogen 2.981 N/A LYS 221.A NZ ASP 197.A OD2 no hydrogen 3.163 N/A GLY 222.A N VAL 217.A O no hydrogen 2.970 N/A PHE 226.A N GLY 222.A O no hydrogen 3.092 N/A LEU 227.A N ILE 223.A O no hydrogen 2.835 N/A GLU 228.A N.A ASP 224.A O no hydrogen 3.350 N/A GLU 228.A N.A ALA 225.A O no hydrogen 3.227 N/A GLU 228.A N.B ALA 225.A O no hydrogen 3.221 N/A THR 229.A N PHE 226.A O no hydrogen 2.814 N/A THR 229.A OG1 HIS 8.A NE2 no hydrogen 3.087 N/A THR 229.A OG1 PHE 226.A O no hydrogen 2.642 N/A