Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 2h6a_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): TYR 10.A OH ASP 87.A OD2 no hydrogen 2.696 N/A SER 15.A OG ASP 36.A OD2 no hydrogen 2.456 N/A TRP 16.A N ASP 13.A O no hydrogen 2.991 N/A LEU 17.A N ALA 14.A O no hydrogen 2.784 N/A GLN 18.A N SER 15.A O no hydrogen 3.324 N/A GLN 18.A NE2 PRO 19.A O no hydrogen 3.093 N/A LEU 23.A N GLN 31.A O no hydrogen 2.883 N/A GLN 24.A NE2 ALA 26.A O no hydrogen 3.112 N/A GLN 24.A NE2 ASP 27.A O no hydrogen 3.385 N/A ILE 25.A N THR 29.A O no hydrogen 2.824 N/A ALA 26.A N THR 29.A O no hydrogen 3.161 N/A ASP 27.A N THR 171.A O no hydrogen 2.801 N/A HIS 28.A N ASP 170.A OD1 no hydrogen 3.160 N/A HIS 28.A N ASP 170.A OD2 no hydrogen 2.848 N/A HIS 28.A ND1 ASP 170.A OD1 no hydrogen 2.542 N/A THR 29.A N ALA 26.A O no hydrogen 3.098 N/A THR 29.A OG1 ASP 170.A OD2 no hydrogen 2.657 N/A TRP 30.A N LEU 41.A O no hydrogen 2.733 N/A GLN 31.A N LEU 23.A O no hydrogen 2.772 N/A GLN 31.A NE2 THR 34.A O no hydrogen 2.910 N/A GLN 31.A NE2 LEU 37.A O no hydrogen 3.115 N/A ILE 32.A N ALA 39.A O no hydrogen 2.725 N/A THR 34.A N LEU 37.A O no hydrogen 3.043 N/A THR 34.A OG1 TRP 16.A O no hydrogen 2.647 N/A THR 34.A OG1 LEU 37.A O no hydrogen 3.556 N/A GLU 35.A N.A GLN 18.A O no hydrogen 2.993 N/A GLU 35.A N.B GLN 18.A O no hydrogen 2.818 N/A ASP 36.A N SER 15.A O no hydrogen 3.134 N/A LEU 37.A N THR 34.A OG1 no hydrogen 3.146 N/A THR 38.A N PRO 223.A O no hydrogen 2.891 N/A THR 38.A OG1 THR 222.A O no hydrogen 2.699 N/A THR 38.A OG1 PRO 223.A O no hydrogen 3.213 N/A THR 38.A OG1 TYR 232.A OH no hydrogen 2.519 N/A ALA 39.A N GLN 31.A OE1 no hydrogen 2.855 N/A LEU 40.A N LEU 51.A O no hydrogen 2.952 N/A LEU 41.A N TRP 30.A O no hydrogen 2.750 N/A VAL 42.A N VAL 49.A O no hydrogen 2.793 N/A GLN 43.A N HIS 28.A O no hydrogen 2.794 N/A GLN 43.A NE2 ARG 69.A O no hydrogen 2.999 N/A THR 44.A N GLY 47.A O no hydrogen 3.068 N/A THR 44.A OG1 GLY 47.A O no hydrogen 2.607 N/A ASP 46.A N THR 44.A OG1 no hydrogen 3.000 N/A GLY 47.A N THR 44.A O no hydrogen 3.245 N/A ALA 48.A N ASP 75.A O no hydrogen 2.923 N/A VAL 49.A N VAL 42.A O no hydrogen 2.869 N/A LEU 50.A N LEU 78.A O no hydrogen 2.872 N/A LEU 51.A N LEU 40.A O no hydrogen 2.820 N/A ASP 52.A N LEU 80.A O no hydrogen 2.865 N/A GLY 53.A N HIS 88.A O no hydrogen 2.785 N/A GLY 54.A N HIS 88.A O no hydrogen 2.987 N/A GLN 57.A N GLN 57.A OE1 no hydrogen 2.666 N/A MET 58.A N MET 55.A O no hydrogen 3.011 N/A HIS 61.A NE2 GLY 33.A O no hydrogen 2.805 N/A LEU 62.A N MET 58.A O no hydrogen 2.978 N/A LEU 63.A N ALA 59.A O no hydrogen 3.017 N/A ASP 64.A N SER 60.A O no hydrogen 2.918 N/A ASN 65.A N HIS 61.A O no hydrogen 2.932 N/A ASN 65.A ND2 MET 20.A O no hydrogen 2.917 N/A ASN 65.A ND2 ILE 32.A O no hydrogen 2.853 N/A MET 66.A N LEU 62.A O no hydrogen 2.783 N/A LYS 67.A N LEU 63.A O no hydrogen 2.932 N/A ALA 68.A N ASP 64.A O no hydrogen 2.922 N/A ARG 69.A N ASN 65.A O no hydrogen 3.091 N/A ARG 69.A N MET 66.A O no hydrogen 2.947 N/A ARG 69.A NH1 GLN 43.A OE1 no hydrogen 2.736 N/A GLY 70.A N LYS 67.A O no hydrogen 2.849 N/A VAL 71.A N MET 66.A O no hydrogen 2.771 N/A THR 72.A N ASP 75.A OD2 no hydrogen 3.108 N/A ASP 75.A N THR 72.A O no hydrogen 2.871 N/A LEU 76.A N PRO 73.A O no hydrogen 3.300 N/A ARG 77.A N ALA 48.A O no hydrogen 2.807 N/A ARG 77.A NH1 ASP 46.A O no hydrogen 2.744 N/A ILE 79.A N LYS 102.A O no hydrogen 2.784 N/A LEU 80.A N LEU 50.A O no hydrogen 2.788 N/A SER 82.A N ASP 52.A OD1 no hydrogen 2.844 N/A SER 82.A OG ASP 52.A OD1 no hydrogen 3.267 N/A SER 82.A OG ASP 52.A OD2 no hydrogen 2.698 N/A SER 82.A OG ASP 183.A OD1 no hydrogen 3.536 N/A HIS 83.A N SER 82.A OG no hydrogen 2.736 N/A HIS 83.A ND1 ASP 183.A OD1 no hydrogen 2.656 N/A HIS 85.A NE2 ASP 120.A OD1 no hydrogen 2.978 N/A HIS 88.A N HIS 85.A O no hydrogen 2.942 N/A ALA 89.A N HIS 85.A O no hydrogen 2.790 N/A VAL 92.A N ALA 89.A O no hydrogen 3.078 N/A LEU 95.A N PRO 91.A O no hydrogen 2.804 N/A LYS 96.A N VAL 92.A O no hydrogen 2.896 N/A LYS 96.A NZ ASN 133.A O no hydrogen 2.879 N/A LYS 96.A NZ ASP 135.A OD1 no hydrogen 3.282 N/A LYS 96.A NZ ASP 135.A OD2 no hydrogen 2.851 N/A ARG 97.A N ALA 93.A O no hydrogen 3.113 N/A ARG 98.A N GLU 94.A O no hydrogen 2.957 N/A ARG 98.A N LEU 95.A O no hydrogen 3.183 N/A ARG 98.A NH1 SER 60.A OG no hydrogen 2.794 N/A ARG 98.A NH1 GLU 94.A OE2 no hydrogen 2.800 N/A THR 99.A OG1 LEU 95.A O no hydrogen 2.751 N/A GLY 100.A N PRO 73.A O no hydrogen 2.994 N/A ALA 101.A N THR 99.A OG1 no hydrogen 2.928 N/A LYS 102.A N ARG 77.A O no hydrogen 3.078 N/A VAL 103.A N ASP 135.A OD2 no hydrogen 2.757 N/A ALA 104.A N ILE 79.A O no hydrogen 3.143 N/A ALA 105.A N ARG 136.A O no hydrogen 2.962 N/A ASN 106.A ND2 GLY 162.A O no hydrogen 2.999 N/A SER 109.A N ASN 106.A OD1 no hydrogen 2.892 N/A SER 109.A OG ASN 106.A OD1 no hydrogen 3.053 N/A SER 109.A OG GLY 162.A O no hydrogen 2.880 N/A ALA 110.A N ASN 106.A O no hydrogen 2.804 N/A VAL 111.A N ALA 107.A O no hydrogen 2.934 N/A LEU 112.A N GLU 108.A O no hydrogen 3.195 N/A LEU 113.A N SER 109.A O no hydrogen 2.829 N/A ALA 114.A N ALA 110.A O no hydrogen 2.866 N/A ARG 115.A N VAL 111.A O no hydrogen 3.129 N/A ARG 115.A N LEU 112.A O no hydrogen 3.214 N/A ARG 115.A NE SER 118.A O no hydrogen 2.720 N/A ARG 115.A NH2 ASP 119.A O no hydrogen 2.798 N/A GLY 116.A N LEU 113.A O no hydrogen 2.935 N/A GLY 117.A N LEU 112.A O no hydrogen 2.988 N/A SER 118.A N ARG 115.A O no hydrogen 3.082 N/A SER 118.A OG ARG 115.A O no hydrogen 2.777 N/A ASP 119.A N ASP 125.A OD1 no hydrogen 2.820 N/A ASP 120.A N GLY 124.A O no hydrogen 2.836 N/A HIS 122.A N ASP 120.A OD2 no hydrogen 2.884 N/A PHE 123.A N ASP 120.A OD2 no hydrogen 2.870 N/A GLY 124.A N ASP 120.A O no hydrogen 3.118 N/A GLY 126.A N PHE 123.A O no hydrogen 2.926 N/A TYR 129.A N GLY 116.A O no hydrogen 2.841 N/A TYR 129.A OH ALA 84.A O no hydrogen 2.648 N/A ALA 132.A N LEU 113.A O no hydrogen 3.001 N/A ASP 135.A N VAL 103.A O no hydrogen 2.741 N/A ARG 136.A N VAL 103.A O no hydrogen 3.111 N/A ARG 136.A NH2 GLU 142.A OE2 no hydrogen 2.974 N/A VAL 138.A N ALA 105.A O no hydrogen 2.953 N/A MET 139.A N GLU 142.A OE1 no hydrogen 2.899 N/A GLY 141.A N ALA 153.A O no hydrogen 2.812 N/A GLU 142.A N MET 139.A O no hydrogen 2.998 N/A ILE 144.A N PHE 151.A O no hydrogen 2.864 N/A VAL 146.A N ILE 149.A O no hydrogen 2.960 N/A ILE 149.A N VAL 146.A O no hydrogen 2.907 N/A PHE 151.A N ILE 144.A O no hydrogen 2.760 N/A THR 152.A N THR 167.A O no hydrogen 2.861 N/A ALA 153.A N GLU 142.A O no hydrogen 2.998 N/A HIS 154.A N ALA 165.A O no hydrogen 2.756 N/A HIS 154.A NE2 THR 167.A OG1 no hydrogen 2.660 N/A PHE 155.A N ASP 140.A OD1 no hydrogen 2.798 N/A MET 156.A N SER 163.A O no hydrogen 2.744 N/A GLY 158.A N THR 160.A O no hydrogen 2.936 N/A HIS 159.A ND1 SER 186.A O no hydrogen 2.915 N/A THR 160.A N SER 163.A OG no hydrogen 3.018 N/A THR 160.A OG1 SER 163.A OG no hydrogen 2.778 N/A SER 163.A N THR 160.A O no hydrogen 3.123 N/A SER 163.A OG THR 160.A O no hydrogen 3.280 N/A SER 163.A OG THR 160.A OG1 no hydrogen 2.778 N/A SER 163.A OG ASP 183.A OD2 no hydrogen 2.538 N/A THR 164.A N SER 82.A O no hydrogen 2.994 N/A THR 164.A OG1 GLY 162.A O no hydrogen 2.978 N/A ALA 165.A N HIS 154.A O no hydrogen 2.774 N/A TRP 166.A N TYR 181.A O no hydrogen 2.971 N/A TRP 166.A NE1 LEU 81.A O no hydrogen 2.992 N/A THR 167.A N THR 152.A O no hydrogen 3.019 N/A THR 167.A OG1 HIS 154.A NE2 no hydrogen 2.660 N/A TRP 168.A N ILE 179.A O no hydrogen 3.080 N/A TRP 168.A NE1 THR 29.A OG1 no hydrogen 3.157 N/A ASP 170.A N VAL 177.A O no hydrogen 2.847 N/A THR 171.A N ASP 170.A OD1 no hydrogen 2.734 N/A THR 171.A OG1 ASP 27.A OD2 no hydrogen 2.515 N/A ARG 172.A N LYS 175.A O no hydrogen 2.908 N/A ARG 172.A NH1 ILE 25.A O no hydrogen 2.978 N/A LYS 175.A N ARG 172.A O no hydrogen 3.208 N/A VAL 177.A N ASP 170.A O no hydrogen 2.710 N/A ARG 178.A N ASP 218.A OD2 no hydrogen 2.819 N/A ARG 178.A NE ASP 218.A OD2 no hydrogen 2.961 N/A ARG 178.A NH2 ASP 218.A OD1 no hydrogen 2.821 N/A ILE 179.A N TRP 168.A O no hydrogen 2.767 N/A ALA 180.A N VAL 219.A O no hydrogen 2.805 N/A TYR 181.A N TRP 166.A O no hydrogen 2.799 N/A TYR 181.A OH ASP 52.A OD2 no hydrogen 2.572 N/A ALA 182.A N LEU 221.A O no hydrogen 3.018 N/A SER 184.A N ASP 183.A OD1 no hydrogen 2.719 N/A SER 184.A OG HIS 159.A ND1 no hydrogen 3.239 N/A SER 184.A OG SER 186.A OG no hydrogen 2.716 N/A SER 186.A N SER 184.A OG no hydrogen 2.993 N/A SER 186.A OG HIS 159.A ND1 no hydrogen 3.050 N/A SER 186.A OG SER 184.A OG no hydrogen 2.716 N/A TYR 190.A N ALA 187.A O no hydrogen 3.114 N/A TYR 190.A OH HIS 159.A O no hydrogen 2.557 N/A GLN 191.A NE2 GLN 193.A O no hydrogen 3.053 N/A LEU 192.A N GLU 263.A OE1 no hydrogen 2.851 N/A GLN 193.A N GLU 263.A OE2 no hydrogen 2.757 N/A GLN 193.A NE2 GLU 263.A OE2 no hydrogen 3.170 N/A GLN 193.A NE2 THR 264.A OG1 no hydrogen 2.849 N/A ASN 195.A ND2 GLN 191.A O no hydrogen 2.904 N/A ARG 197.A N ASN 195.A OD1 no hydrogen 3.020 N/A ARG 197.A NH1 ASP 119.A OD1 no hydrogen 3.381 N/A ARG 197.A NH2 ASP 119.A OD1 no hydrogen 3.306 N/A ARG 197.A NH2 ASP 119.A OD2 no hydrogen 3.507 N/A TYR 198.A N ASN 195.A O no hydrogen 3.013 N/A TYR 198.A OH ASP 204.A OD2 no hydrogen 2.536 N/A HIS 200.A ND1 GLU 203.A OE1.B no hydrogen 2.718 N/A LEU 201.A N TYR 198.A O no hydrogen 3.067 N/A GLU 203.A N.B GLU 203.A OE2.B no hydrogen 2.942 N/A ASP 204.A N HIS 200.A O no hydrogen 2.974 N/A TYR 205.A N LEU 201.A O no hydrogen 2.976 N/A TYR 205.A OH SER 186.A O no hydrogen 2.660 N/A ARG 206.A N ILE 202.A O no hydrogen 2.935 N/A ARG 206.A NH1 GLU 253.A OE2 no hydrogen 2.892 N/A ARG 206.A NH1 ASP 257.A OD1 no hydrogen 2.825 N/A ARG 206.A NH2 ASP 257.A OD1 no hydrogen 2.737 N/A ARG 207.A N GLU 203.A O.A no hydrogen 2.962 N/A ARG 207.A N GLU 203.A O.B no hydrogen 3.106 N/A SER 208.A N ASP 204.A O no hydrogen 2.891 N/A SER 208.A OG ALA 157.A O no hydrogen 2.693 N/A SER 208.A OG ASP 204.A O no hydrogen 3.013 N/A PHE 209.A N TYR 205.A O no hydrogen 2.864 N/A ALA 210.A N ARG 206.A O no hydrogen 3.318 N/A THR 211.A N ARG 207.A O no hydrogen 2.954 N/A THR 211.A OG1 ARG 207.A O no hydrogen 3.131 N/A VAL 212.A N SER 208.A O no hydrogen 2.870 N/A ARG 213.A N PHE 209.A O no hydrogen 2.897 N/A ALA 214.A N ALA 210.A O no hydrogen 3.170 N/A ALA 214.A N THR 211.A O no hydrogen 3.164 N/A LEU 215.A N VAL 212.A O no hydrogen 3.207 N/A ASP 218.A N ARG 178.A O no hydrogen 2.736 N/A VAL 219.A N ARG 178.A O no hydrogen 3.129 N/A LEU 221.A N ALA 180.A O no hydrogen 2.880 N/A THR 222.A OG1 HIS 224.A O no hydrogen 2.722 N/A THR 222.A OG1 SER 228.A OG no hydrogen 2.651 N/A HIS 224.A ND1 ASP 36.A O no hydrogen 3.010 N/A ALA 227.A N HIS 224.A O no hydrogen 3.044 N/A SER 228.A N PRO 225.A O no hydrogen 3.123 N/A SER 228.A OG THR 222.A OG1 no hydrogen 2.651 N/A SER 228.A OG PRO 225.A O no hydrogen 3.399 N/A ASN 229.A N GLY 226.A O no hydrogen 3.155 N/A ASN 229.A ND2 LYS 241.A O no hydrogen 3.563 N/A TRP 230.A N PRO 225.A O no hydrogen 2.871 N/A TRP 230.A NE1 LEU 220.A O no hydrogen 2.737 N/A ASP 231.A N ALA 238.A O no hydrogen 2.948 N/A TYR 232.A OH THR 38.A OG1 no hydrogen 2.519 N/A ALA 233.A N ASP 231.A OD1 no hydrogen 3.130 N/A ALA 234.A N ASP 231.A O no hydrogen 2.971 N/A ARG 237.A N ALA 234.A O no hydrogen 3.028 N/A ALA 238.A N GLY 235.A O no hydrogen 2.697 N/A ALA 240.A N ARG 237.A O no hydrogen 3.143 N/A ALA 242.A N GLY 239.A O no hydrogen 3.195 N/A LEU 243.A N SER 228.A O no hydrogen 2.853 N/A ALA 247.A N THR 244.A OG1 no hydrogen 2.905 N/A TYR 248.A N THR 244.A O no hydrogen 2.962 N/A TYR 248.A OH ASP 183.A O no hydrogen 2.666 N/A ALA 249.A N CYS 245.A O no hydrogen 2.891 N/A ASP 250.A N LYS 246.A O no hydrogen 2.906 N/A ALA 251.A N ALA 247.A O no hydrogen 2.889 N/A ALA 252.A N TYR 248.A O no hydrogen 3.021 N/A GLU 253.A N ALA 249.A O no hydrogen 2.821 N/A GLN 254.A N ASP 250.A O no hydrogen 2.924 N/A LYS 255.A N ALA 251.A O no hydrogen 2.941 N/A PHE 256.A N ALA 252.A O no hydrogen 2.838 N/A ASP 257.A N GLU 253.A O no hydrogen 2.876 N/A GLY 258.A N GLN 254.A O no hydrogen 3.086 N/A GLN 259.A N LYS 255.A O no hydrogen 2.829 N/A GLN 259.A NE2 ALA 187.A O no hydrogen 2.685 N/A GLN 259.A NE2 TYR 190.A O no hydrogen 3.695 N/A LEU 260.A N PHE 256.A O no hydrogen 2.771 N/A ALA 261.A N ASP 257.A O no hydrogen 3.081 N/A LYS 262.A N GLY 258.A O no hydrogen 2.855 N/A GLU 263.A N GLN 259.A O no hydrogen 2.807 N/A THR 264.A N LEU 260.A O no hydrogen 2.956 N/A THR 264.A OG1 LEU 260.A O no hydrogen 3.189 N/A ALA 265.A N ALA 261.A O no hydrogen 2.983 N/A GLY 266.A N GLU 263.A O no hydrogen 2.944 N/A