Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 2i0e_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): PHE 4.A N LEU 1.A O no hydrogen 3.241 N/A ASN 5.A N GLU 22.A O no hydrogen 3.060 N/A ASN 5.A ND2 GLU 22.A OE2 no hydrogen 3.006 N/A LEU 7.A N LEU 20.A O no hydrogen 2.880 N/A LEU 10.A N VAL 18.A O no hydrogen 2.659 N/A GLY 11.A N VAL 18.A O no hydrogen 3.419 N/A GLY 13.A N GLY 16.A O no hydrogen 2.923 N/A GLY 16.A N GLY 13.A O no hydrogen 2.778 N/A LYS 17.A N ILE 34.A O no hydrogen 3.250 N/A VAL 18.A N GLY 11.A O no hydrogen 2.928 N/A MET 19.A N VAL 32.A O no hydrogen 2.824 N/A LEU 20.A N MET 8.A O no hydrogen 2.805 N/A SER 21.A N TYR 30.A O no hydrogen 2.774 N/A SER 21.A OG MET 19.A O no hydrogen 3.088 N/A GLU 22.A N ASN 5.A O no hydrogen 2.866 N/A ARG 23.A N GLU 28.A O no hydrogen 3.282 N/A ARG 23.A NH1 GLU 28.A OE1 no hydrogen 3.119 N/A LYS 24.A N ASP 3.A O no hydrogen 2.699 N/A LYS 24.A NZ THR 2.A O no hydrogen 3.086 N/A THR 26.A N LYS 24.A O no hydrogen 2.779 N/A THR 26.A OG1 LYS 24.A O no hydrogen 3.324 N/A TYR 30.A N SER 21.A O no hydrogen 2.911 N/A TYR 30.A OH GLU 28.A OE1 no hydrogen 3.019 N/A ALA 31.A N MET 82.A O no hydrogen 2.828 N/A VAL 32.A N MET 19.A O no hydrogen 2.855 N/A LYS 33.A N PHE 80.A O no hydrogen 2.820 N/A LYS 33.A NZ PHE 15.A O no hydrogen 2.768 N/A LYS 33.A NZ GLU 52.A OE1 no hydrogen 3.031 N/A LYS 33.A NZ GLU 52.A OE2 no hydrogen 3.124 N/A ILE 34.A N LYS 17.A O no hydrogen 2.733 N/A LEU 35.A N LEU 78.A O no hydrogen 2.995 N/A LYS 37.A N ASP 76.A O no hydrogen 2.830 N/A LYS 37.A NZ GLN 73.A OE1 no hydrogen 2.897 N/A LYS 37.A NZ THR 74.A O no hydrogen 2.398 N/A LYS 37.A NZ GLN 311.A OE1 no hydrogen 3.570 N/A VAL 39.A N LYS 36.A O no hydrogen 3.073 N/A VAL 40.A N LYS 36.A O no hydrogen 3.232 N/A ILE 41.A N LYS 37.A O no hydrogen 2.950 N/A GLN 42.A N ASP 38.A O no hydrogen 2.817 N/A ASP 43.A N VAL 39.A O no hydrogen 2.908 N/A ASP 44.A N ILE 41.A O no hydrogen 2.817 N/A ASP 45.A N VAL 40.A O no hydrogen 2.678 N/A GLU 47.A N GLU 47.A OE2 no hydrogen 2.732 N/A CYS 48.A SG ASP 45.A O no hydrogen 3.468 N/A THR 49.A N ASP 45.A O no hydrogen 3.251 N/A THR 49.A N VAL 46.A O no hydrogen 3.178 N/A THR 49.A OG1 ASP 45.A O no hydrogen 2.622 N/A MET 50.A N VAL 46.A O no hydrogen 3.160 N/A VAL 51.A N GLU 47.A O no hydrogen 2.788 N/A GLU 52.A N CYS 48.A O no hydrogen 2.962 N/A LYS 53.A N THR 49.A O no hydrogen 3.106 N/A LYS 53.A NZ PHE 317.A O no hydrogen 2.699 N/A ARG 54.A N MET 50.A O no hydrogen 2.823 N/A ARG 54.A NE GLU 152.A OE2 no hydrogen 2.933 N/A ARG 54.A NH2 GLU 152.A OE1 no hydrogen 2.882 N/A ARG 54.A NH2 GLU 152.A OE2 no hydrogen 3.399 N/A VAL 55.A N VAL 51.A O no hydrogen 2.858 N/A LEU 56.A N GLU 52.A O no hydrogen 2.929 N/A ALA 57.A N LYS 53.A O no hydrogen 3.001 N/A LEU 58.A N VAL 55.A O no hydrogen 3.337 N/A GLY 60.A N GLU 322.A OE1 no hydrogen 3.317 N/A GLY 60.A N GLU 322.A OE2 no hydrogen 3.099 N/A LYS 61.A NZ LEU 56.A O no hydrogen 2.876 N/A LYS 61.A NZ THR 66.A O no hydrogen 2.992 N/A LEU 65.A N PRO 62.A O no hydrogen 3.456 N/A THR 66.A N ILE 144.A O no hydrogen 3.112 N/A GLN 67.A N GLU 83.A OE1 no hydrogen 2.788 N/A GLN 67.A NE2 GLU 83.A OE2 no hydrogen 3.298 N/A GLN 67.A NE2 LEU 324.A O no hydrogen 2.830 N/A HIS 69.A N VAL 81.A O no hydrogen 2.721 N/A HIS 69.A ND1 SER 70.A OG no hydrogen 2.798 N/A SER 70.A OG HIS 69.A ND1 no hydrogen 2.798 N/A CYS 71.A N PHE 318.A O no hydrogen 2.753 N/A PHE 72.A N TYR 79.A O no hydrogen 3.174 N/A GLN 73.A NE2 PHE 314.A O no hydrogen 3.178 N/A THR 74.A N ARG 77.A O no hydrogen 3.204 N/A THR 74.A OG1 ASP 76.A OD1 no hydrogen 3.433 N/A ARG 77.A NE ASP 76.A OD2 no hydrogen 3.245 N/A LEU 78.A N LEU 35.A O no hydrogen 2.683 N/A TYR 79.A N PHE 72.A O no hydrogen 2.916 N/A PHE 80.A N LYS 33.A O no hydrogen 2.883 N/A VAL 81.A N SER 70.A O no hydrogen 2.909 N/A MET 82.A N ALA 31.A O no hydrogen 2.836 N/A GLU 83.A N GLN 67.A O no hydrogen 3.033 N/A LEU 90.A N VAL 134.A O no hydrogen 3.043 N/A HIS 93.A N ASP 89.A O no hydrogen 3.387 N/A HIS 93.A NE2 GLY 87.A O no hydrogen 2.853 N/A ILE 94.A N LEU 90.A O no hydrogen 2.947 N/A GLN 95.A N MET 91.A O no hydrogen 2.909 N/A GLN 96.A N TYR 92.A O no hydrogen 3.279 N/A VAL 97.A N ILE 94.A O no hydrogen 3.114 N/A GLY 98.A N GLN 95.A O no hydrogen 3.356 N/A PHE 100.A N MET 195.A O no hydrogen 3.089 N/A ALA 105.A N LYS 101.A O no hydrogen 3.090 N/A VAL 106.A N GLU 102.A O no hydrogen 2.847 N/A PHE 107.A N PRO 103.A O no hydrogen 3.300 N/A TYR 108.A N HIS 104.A O no hydrogen 3.054 N/A ALA 109.A N ALA 105.A O no hydrogen 2.780 N/A ALA 110.A N VAL 106.A O no hydrogen 2.871 N/A GLU 111.A N PHE 107.A O no hydrogen 3.163 N/A ILE 112.A N TYR 108.A O no hydrogen 2.956 N/A ALA 113.A N ALA 109.A O no hydrogen 2.820 N/A ILE 114.A N ALA 110.A O no hydrogen 2.999 N/A GLY 115.A N GLU 111.A O no hydrogen 3.480 N/A LEU 116.A N ILE 112.A O no hydrogen 3.157 N/A PHE 117.A N ALA 113.A O no hydrogen 2.692 N/A PHE 118.A N ILE 114.A O no hydrogen 3.143 N/A LEU 119.A N GLY 115.A O no hydrogen 3.274 N/A GLN 120.A N LEU 116.A O no hydrogen 2.927 N/A GLN 120.A NE2 ASP 184.A OD2 no hydrogen 3.395 N/A SER 121.A N PHE 117.A O no hydrogen 2.777 N/A SER 121.A OG PHE 118.A O no hydrogen 3.044 N/A LYS 122.A N PHE 118.A O no hydrogen 3.206 N/A ILE 124.A N LEU 119.A O no hydrogen 3.202 N/A ILE 125.A N LYS 151.A O no hydrogen 2.980 N/A TYR 126.A N ASP 184.A OD2 no hydrogen 2.708 N/A TYR 126.A OH ALA 145.A O no hydrogen 2.658 N/A TYR 126.A OH ASP 146.A O no hydrogen 3.394 N/A ARG 127.A N ASP 184.A OD1 no hydrogen 2.756 N/A ARG 127.A NE MET 149.A O no hydrogen 2.766 N/A ARG 127.A NH1 TYR 179.A OH no hydrogen 2.934 N/A ARG 127.A NH2 MET 149.A O no hydrogen 3.056 N/A LEU 131.A N TYR 168.A OH no hydrogen 3.181 N/A ASN 133.A N LYS 130.A O no hydrogen 3.098 N/A ASN 133.A ND2 ASP 128.A O no hydrogen 3.102 N/A VAL 134.A N LEU 131.A O no hydrogen 3.234 N/A MET 135.A N LYS 143.A O no hydrogen 2.856 N/A LEU 136.A N GLY 88.A O no hydrogen 3.018 N/A ASP 137.A N HIS 141.A O no hydrogen 2.716 N/A GLU 139.A N ASP 137.A OD1 no hydrogen 3.157 N/A GLY 140.A N ASP 137.A O no hydrogen 2.975 N/A HIS 141.A N ASP 137.A OD1 no hydrogen 2.861 N/A HIS 141.A ND1 GLU 111.A OE2 no hydrogen 2.820 N/A ILE 142.A N GLU 111.A OE1 no hydrogen 2.998 N/A LYS 143.A N MET 135.A O no hydrogen 2.936 N/A LYS 143.A NZ PRO 63.A O no hydrogen 2.659 N/A LYS 143.A NZ GLU 83.A OE1 no hydrogen 2.898 N/A ILE 144.A N PHE 64.A O no hydrogen 2.838 N/A ALA 145.A N ASN 133.A O no hydrogen 2.803 N/A GLY 148.A N ASP 146.A OD2 no hydrogen 3.292 N/A CYS 150.A SG ILE 125.A O no hydrogen 3.912 N/A CYS 150.A SG TYR 126.A O no hydrogen 3.905 N/A CYS 150.A SG PHE 147.A O no hydrogen 3.639 N/A LYS 151.A N ILE 125.A O no hydrogen 3.072 N/A ILE 154.A N GLY 123.A O no hydrogen 2.662 N/A VAL 158.A N TRP 155.A O no hydrogen 2.909 N/A THR 160.A N TYR 179.A O no hydrogen 2.800 N/A TYR 168.A N THR 165.A O no hydrogen 2.935 N/A ILE 169.A N PRO 166.A O no hydrogen 3.481 N/A GLU 172.A N GLU 172.A OE1 no hydrogen 2.909 N/A ILE 173.A N ALA 170.A O no hydrogen 3.253 N/A ILE 174.A N ALA 170.A O no hydrogen 3.333 N/A ALA 175.A N PRO 171.A O no hydrogen 2.911 N/A TYR 176.A N ILE 173.A O no hydrogen 3.279 N/A GLN 177.A N GLU 172.A O no hydrogen 2.947 N/A TYR 179.A N THR 160.A O no hydrogen 2.830 N/A LYS 181.A NZ ASP 156.A OD1 no hydrogen 3.290 N/A LYS 181.A NZ GLY 248.A O no hydrogen 3.362 N/A VAL 183.A N GLY 180.A O no hydrogen 3.257 N/A ASP 184.A N LYS 181.A O no hydrogen 3.101 N/A TRP 185.A NE1 GLN 120.A OE1 no hydrogen 3.133 N/A TRP 186.A N SER 182.A O no hydrogen 3.221 N/A ALA 187.A N VAL 183.A O no hydrogen 3.068 N/A PHE 188.A N ASP 184.A O no hydrogen 2.869 N/A GLY 189.A N TRP 185.A O no hydrogen 2.891 N/A VAL 190.A N TRP 186.A O no hydrogen 2.975 N/A LEU 191.A N ALA 187.A O no hydrogen 2.965 N/A LEU 192.A N PHE 188.A O no hydrogen 2.929 N/A TYR 193.A N GLY 189.A O no hydrogen 3.056 N/A TYR 193.A OH ALA 220.A O no hydrogen 2.704 N/A GLU 194.A N VAL 190.A O no hydrogen 2.993 N/A MET 195.A N LEU 191.A O no hydrogen 3.127 N/A LEU 196.A N LEU 192.A O no hydrogen 2.874 N/A ALA 197.A N TYR 193.A O no hydrogen 2.705 N/A GLY 198.A N GLU 194.A O no hydrogen 2.757 N/A GLU 205.A N GLU 209.A OE1 no hydrogen 2.460 N/A ASP 206.A N GLU 209.A OE1 no hydrogen 3.228 N/A ASP 208.A N ASP 206.A OD1 no hydrogen 2.939 N/A LEU 210.A N ASP 206.A O no hydrogen 3.296 N/A PHE 211.A N GLU 207.A O no hydrogen 3.351 N/A GLN 212.A N ASP 208.A O no hydrogen 3.096 N/A GLN 212.A NE2 GLU 216.A OE1 no hydrogen 2.659 N/A SER 213.A N GLU 209.A O no hydrogen 3.005 N/A ILE 214.A N LEU 210.A O no hydrogen 3.074 N/A MET 215.A N PHE 211.A O no hydrogen 3.235 N/A GLU 216.A N GLN 212.A O no hydrogen 2.953 N/A HIS 217.A N SER 213.A O no hydrogen 2.776 N/A MET 225.A N PRO 222.A O no hydrogen 3.247 N/A SER 226.A OG GLU 102.A OE2 no hydrogen 2.619 N/A SER 226.A OG GLU 228.A OE2 no hydrogen 3.277 N/A GLU 228.A N GLU 228.A OE2 no hydrogen 2.760 N/A ALA 229.A N SER 226.A OG no hydrogen 3.234 N/A VAL 230.A N SER 226.A O no hydrogen 3.097 N/A ALA 231.A N LYS 227.A O no hydrogen 3.089 N/A ILE 232.A N GLU 228.A O no hydrogen 2.957 N/A CYS 233.A N ALA 229.A O no hydrogen 3.059 N/A CYS 233.A SG ALA 229.A O no hydrogen 3.431 N/A LYS 234.A N VAL 230.A O no hydrogen 2.858 N/A GLY 235.A N ALA 231.A O no hydrogen 3.018 N/A GLY 235.A N ILE 232.A O no hydrogen 2.990 N/A LEU 236.A N ILE 232.A O no hydrogen 2.976 N/A MET 237.A N CYS 233.A O no hydrogen 2.988 N/A THR 238.A OG1 LYS 234.A O no hydrogen 2.972 N/A THR 238.A OG1 GLY 235.A O no hydrogen 3.181 N/A LYS 239.A NZ ILE 214.A O no hydrogen 2.793 N/A LYS 239.A NZ HIS 217.A O no hydrogen 2.852 N/A GLY 242.A N HIS 240.A ND1 no hydrogen 3.314 N/A LYS 243.A N HIS 240.A O no hydrogen 3.047 N/A ARG 244.A NE THR 238.A O no hydrogen 2.774 N/A ARG 244.A NH1 GLU 172.A OE1 no hydrogen 3.108 N/A ARG 244.A NH1 GLU 172.A OE2 no hydrogen 2.778 N/A ARG 244.A NH1 SER 182.A O no hydrogen 3.054 N/A ARG 244.A NH2 GLU 172.A OE1 no hydrogen 2.711 N/A ARG 244.A NH2 THR 238.A O no hydrogen 3.054 N/A ARG 244.A NH2 LYS 239.A O no hydrogen 3.083 N/A LEU 245.A N GLY 235.A O no hydrogen 2.670 N/A CYS 247.A N ARG 244.A O no hydrogen 3.104 N/A CYS 247.A SG SER 182.A OG no hydrogen 3.190 N/A CYS 247.A SG PRO 241.A O no hydrogen 3.764 N/A GLY 251.A N GLY 248.A O no hydrogen 3.122 N/A ASP 254.A N GLU 250.A O no hydrogen 2.871 N/A ILE 255.A N GLY 251.A O no hydrogen 3.294 N/A LYS 256.A N GLU 252.A O no hydrogen 3.113 N/A LYS 256.A NZ GLU 252.A OE2 no hydrogen 3.303 N/A GLU 257.A N ARG 253.A O no hydrogen 2.982 N/A HIS 258.A N ILE 255.A O no hydrogen 2.994 N/A PHE 260.A N HIS 258.A ND1 no hydrogen 2.994 N/A PHE 261.A N HIS 258.A O no hydrogen 2.980 N/A ARG 262.A N ALA 259.A O no hydrogen 3.008 N/A ARG 262.A NE ALA 259.A O no hydrogen 2.818 N/A ILE 264.A N PHE 261.A O no hydrogen 2.833 N/A TRP 266.A NE1 LYS 256.A O no hydrogen 3.131 N/A LYS 268.A N ASP 265.A OD2 no hydrogen 2.933 N/A LEU 269.A N ASP 265.A O no hydrogen 2.962 N/A GLU 270.A N TRP 266.A O no hydrogen 3.124 N/A ARG 271.A N LYS 268.A O no hydrogen 3.194 N/A ARG 271.A NH1 GLU 273.A OE2 no hydrogen 2.976 N/A LYS 272.A N LEU 269.A O no hydrogen 2.902 N/A GLU 273.A N LYS 268.A O no hydrogen 3.115 N/A ARG 285.A NH1 GLU 22.A OE1 no hydrogen 3.478 N/A PHE 291.A N ASN 287.A O no hydrogen 2.928 N/A PHE 292.A N PHE 288.A O no hydrogen 3.407 N/A THR 293.A OG1 ASP 289.A O no hydrogen 2.714 N/A ARG 294.A N ARG 290.A O no hydrogen 2.847 N/A HIS 295.A N PHE 291.A O no hydrogen 2.803 N/A GLU 304.A N ASP 302.A OD1 no hydrogen 3.186 N/A ILE 306.A N ASP 302.A O no hydrogen 3.173 N/A ARG 307.A N GLN 303.A O no hydrogen 3.051 N/A ARG 307.A NE GLU 304.A OE1 no hydrogen 3.408 N/A ASN 308.A N VAL 305.A O no hydrogen 3.158 N/A ILE 309.A N VAL 305.A O no hydrogen 3.069 N/A ILE 309.A N ILE 306.A O no hydrogen 2.955 N/A GLN 311.A NE2 MET 75.A O no hydrogen 3.232 N/A SER 312.A N ASP 310.A OD1 no hydrogen 3.429 N/A SER 312.A OG ASP 310.A OD1 no hydrogen 3.026 N/A GLU 313.A N ASP 310.A O no hydrogen 3.202 N/A GLU 315.A N SER 312.A O no hydrogen 3.400 N/A ASN 320.A N HIS 69.A O no hydrogen 2.921 N/A ASN 320.A ND2 LEU 68.A O no hydrogen 2.806 N/A GLU 322.A N ASN 320.A OD1 no hydrogen 3.054 N/A LEU 324.A N GLN 67.A OE1 no hydrogen 2.760 N/A