Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 2q8d_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): SER 3.A N GLU 6.A OE1 no hydrogen 3.372 N/A SER 3.A OG SER 5.A OG no hydrogen 3.307 N/A SER 5.A OG SER 3.A OG no hydrogen 3.307 N/A SER 5.A OG THR 344.A OG1 no hydrogen 3.050 N/A GLU 6.A N SER 3.A OG no hydrogen 3.239 N/A THR 7.A N GLU 4.A O no hydrogen 3.180 N/A THR 7.A OG1 SER 3.A O no hydrogen 2.709 N/A LEU 8.A N SER 5.A O no hydrogen 3.185 N/A ASN 9.A ND2 ARG 13.A O no hydrogen 2.904 N/A ASN 9.A ND2 GLY 38.A O no hydrogen 2.913 N/A ALA 12.A N ASN 9.A O no hydrogen 2.915 N/A ARG 13.A N ASN 9.A OD1 no hydrogen 2.959 N/A ILE 14.A N ASP 258.A OD2 no hydrogen 2.785 N/A PHE 17.A N LYS 46.A O no hydrogen 2.880 N/A THR 20.A N GLU 23.A OE2 no hydrogen 3.139 N/A GLU 22.A N GLU 22.A OE2 no hydrogen 2.753 N/A PHE 24.A N THR 20.A O no hydrogen 2.922 N/A ARG 25.A N MET 21.A O no hydrogen 3.217 N/A TYR 30.A N ASN 26.A O no hydrogen 2.917 N/A ILE 31.A N PHE 27.A O no hydrogen 2.991 N/A ALA 32.A N SER 28.A O no hydrogen 3.176 N/A TYR 33.A N ARG 29.A O no hydrogen 2.852 N/A ILE 34.A N TYR 30.A O no hydrogen 3.036 N/A GLU 35.A N ILE 31.A O no hydrogen 3.089 N/A SER 36.A N ALA 32.A O no hydrogen 3.065 N/A SER 36.A OG TYR 33.A O no hydrogen 2.548 N/A GLN 37.A N ILE 34.A O no hydrogen 3.268 N/A GLY 38.A N GLU 35.A O no hydrogen 2.910 N/A ALA 39.A N ILE 34.A O no hydrogen 2.986 N/A HIS 40.A NE2 THR 344.A O no hydrogen 2.797 N/A ARG 41.A N GLY 38.A O no hydrogen 3.038 N/A ARG 41.A NE GLU 214.A OE1 no hydrogen 2.816 N/A ARG 41.A NH1 GLU 6.A O no hydrogen 2.629 N/A ARG 41.A NH1 LEU 8.A O no hydrogen 3.024 N/A ARG 41.A NH2 GLU 214.A OE1 no hydrogen 3.419 N/A ARG 41.A NH2 GLU 214.A OE2 no hydrogen 2.935 N/A ALA 42.A N ALA 39.A O no hydrogen 3.141 N/A GLY 43.A N HIS 40.A O no hydrogen 3.094 N/A ALA 45.A N ILE 269.A O no hydrogen 2.801 N/A LYS 46.A N MET 15.A O no hydrogen 2.975 N/A LYS 46.A NZ THR 261.A O no hydrogen 2.786 N/A LYS 46.A NZ GLU 266.A OE2 no hydrogen 3.237 N/A VAL 47.A N PHE 267.A O no hydrogen 2.835 N/A VAL 48.A N PHE 17.A O no hydrogen 2.920 N/A TRP 53.A NE1 GLU 147.A OE1 no hydrogen 3.048 N/A ARG 56.A NE LEU 140.A O no hydrogen 2.807 N/A ARG 56.A NH1 SER 58.A O no hydrogen 2.818 N/A ARG 56.A NH1 ASP 61.A OD1 no hydrogen 3.399 N/A ARG 56.A NH1 ASP 61.A OD2 no hydrogen 2.551 N/A TYR 59.A OH HIS 201.A ND1 no hydrogen 2.964 N/A LEU 65.A N ILE 62.A O no hydrogen 3.193 N/A ILE 67.A N MET 92.A O no hydrogen 2.747 N/A ILE 71.A N TYR 132.A O no hydrogen 3.067 N/A GLN 72.A N ILE 87.A O no hydrogen 2.558 N/A GLN 72.A NE2 PRO 129.A O no hydrogen 3.018 N/A GLN 73.A N PRO 130.A O no hydrogen 2.914 N/A GLN 73.A NE2 SER 184.A O no hydrogen 3.147 N/A LEU 74.A N TYR 85.A O no hydrogen 2.806 N/A THR 76.A N THR 83.A O no hydrogen 2.946 N/A GLN 78.A N LEU 81.A O no hydrogen 3.121 N/A SER 79.A OG GLN 78.A O no hydrogen 2.917 N/A SER 79.A OG SER 79.A O no hydrogen 2.274 N/A LEU 81.A N GLN 78.A O no hydrogen 3.204 N/A PHE 82.A N LEU 244.A O no hydrogen 2.957 N/A THR 83.A N THR 76.A O no hydrogen 2.847 N/A GLN 84.A N MET 242.A O no hydrogen 2.663 N/A TYR 85.A N LEU 74.A O no hydrogen 2.630 N/A ILE 87.A N GLN 72.A O no hydrogen 2.755 N/A LYS 89.A N PRO 70.A O no hydrogen 2.785 N/A LYS 89.A NZ GLN 72.A OE1 no hydrogen 2.985 N/A MET 92.A N ILE 67.A O no hydrogen 3.106 N/A THR 93.A N GLU 96.A OE1.A no hydrogen 2.794 N/A THR 93.A OG1 GLU 96.A OE1.A no hydrogen 3.112 N/A VAL 94.A N LEU 65.A O no hydrogen 2.923 N/A ARG 95.A N ASP 63.A O no hydrogen 2.931 N/A GLU 96.A N THR 93.A OG1 no hydrogen 3.130 N/A PHE 97.A N THR 93.A O no hydrogen 2.995 N/A ARG 98.A N VAL 94.A O no hydrogen 2.682 N/A ARG 98.A NH1 ASP 63.A OD1 no hydrogen 3.210 N/A ARG 98.A NH2 ASP 63.A OD2 no hydrogen 2.837 N/A LYS 99.A N ARG 95.A O no hydrogen 3.079 N/A ALA 101.A N PHE 97.A O no hydrogen 2.916 N/A ASN 102.A N ARG 98.A O no hydrogen 2.962 N/A SER 103.A N ILE 100.A O no hydrogen 3.385 N/A SER 103.A OG ILE 100.A O no hydrogen 2.595 N/A TYR 106.A N SER 103.A O no hydrogen 2.927 N/A CYS 107.A N SER 103.A O no hydrogen 2.894 N/A CYS 107.A SG SER 103.A O no hydrogen 3.567 N/A CYS 107.A SG ASP 104.A O no hydrogen 3.732 N/A THR 108.A OG1 HIS 281.A O no hydrogen 2.512 N/A SER 112.A N GLU 116.A OE1 no hydrogen 2.707 N/A GLU 116.A N GLU 113.A O no hydrogen 2.944 N/A LEU 117.A N GLU 113.A O no hydrogen 3.358 N/A GLU 118.A N PHE 114.A O no hydrogen 2.714 N/A ARG 119.A N GLU 115.A O no hydrogen 3.017 N/A LYS 120.A N GLU 116.A O no hydrogen 2.994 N/A LYS 120.A NZ ARG 110.A O no hydrogen 3.488 N/A TYR 121.A N LEU 117.A O no hydrogen 2.900 N/A TRP 122.A N GLU 118.A O no hydrogen 3.198 N/A TRP 122.A NE1 TYR 209.A OH no hydrogen 2.889 N/A LYS 123.A N ARG 119.A O no hydrogen 2.988 N/A ASN 124.A N LYS 120.A O no hydrogen 3.020 N/A ASN 124.A N TYR 121.A O no hydrogen 3.353 N/A ASN 124.A ND2 LYS 120.A O no hydrogen 2.962 N/A PHE 127.A N ASN 124.A O no hydrogen 3.017 N/A TYR 132.A N ILE 71.A O no hydrogen 2.908 N/A GLY 133.A N PHE 178.A O no hydrogen 2.731 N/A VAL 136.A N LEU 176.A O no hydrogen 2.958 N/A ASN 137.A ND2 GLU 169.A OE1 no hydrogen 2.857 N/A GLY 138.A N PRO 174.A O no hydrogen 3.367 N/A LEU 140.A N GLU 287.A OE2 no hydrogen 2.910 N/A TYR 141.A OH TRP 148.A O no hydrogen 2.866 N/A GLU 142.A N PRO 55.A O no hydrogen 2.767 N/A VAL 145.A N GLU 142.A O no hydrogen 3.100 N/A TRP 148.A NE1 PHE 24.A O no hydrogen 2.734 N/A ASN 149.A ND2 VAL 145.A O no hydrogen 2.893 N/A GLY 151.A N ASN 149.A OD1 no hydrogen 2.943 N/A ARG 152.A N ASN 149.A O no hydrogen 2.692 N/A ARG 152.A NH1 ASP 146.A OD1 no hydrogen 2.867 N/A ARG 152.A NH2 LYS 143.A O no hydrogen 2.655 N/A ARG 152.A NH2 ASP 146.A OD1 no hydrogen 2.893 N/A ASP 158.A N THR 155.A O no hydrogen 3.193 N/A LEU 159.A N ILE 156.A O no hydrogen 2.973 N/A VAL 160.A N LEU 157.A O no hydrogen 3.075 N/A LYS 162.A N ASP 158.A O no hydrogen 3.000 N/A GLU 163.A N LEU 159.A O no hydrogen 2.805 N/A SER 164.A N VAL 160.A O no hydrogen 2.982 N/A SER 164.A OG VAL 160.A O no hydrogen 2.643 N/A GLY 165.A N GLU 161.A O no hydrogen 2.679 N/A ILE 166.A N SER 164.A OG no hydrogen 3.082 N/A ILE 168.A N ASN 172.A OD1 no hydrogen 2.671 N/A GLY 170.A N THR 173.A OG1 no hydrogen 3.088 N/A VAL 171.A N ILE 168.A O no hydrogen 2.923 N/A ASN 172.A N ILE 168.A O no hydrogen 2.961 N/A ASN 172.A ND2 ILE 166.A O no hydrogen 3.038 N/A TYR 175.A N SER 288.A O no hydrogen 2.909 N/A LEU 176.A N VAL 136.A O no hydrogen 2.585 N/A TYR 177.A N ALA 286.A O no hydrogen 2.722 N/A PHE 178.A N GLY 133.A O no hydrogen 2.844 N/A GLY 179.A N ASN 284.A O no hydrogen 2.942 N/A LYS 182.A N ASN 280.A O no hydrogen 3.089 N/A LYS 182.A NZ ASN 124.A O no hydrogen 3.111 N/A LYS 182.A NZ PHE 127.A O no hydrogen 2.769 N/A THR 183.A N MET 180.A O no hydrogen 3.200 N/A THR 183.A OG1 MET 180.A O no hydrogen 2.776 N/A SER 184.A N GLN 73.A OE1 no hydrogen 2.871 N/A SER 184.A OG TYR 121.A OH no hydrogen 3.136 N/A PHE 185.A N GLY 278.A O no hydrogen 2.935 N/A TRP 187.A N THR 243.A O no hydrogen 3.060 N/A TRP 187.A NE1 ILE 245.A O no hydrogen 2.882 N/A HIS 188.A N HIS 276.A O no hydrogen 3.087 N/A HIS 188.A ND1 ALA 186.A O no hydrogen 2.650 N/A THR 189.A OG1 ASP 193.A OD1 no hydrogen 2.823 N/A ASP 193.A N GLU 190.A O no hydrogen 2.929 N/A LEU 194.A N ASP 191.A O no hydrogen 3.056 N/A TYR 195.A N PHE 291.A O no hydrogen 3.100 N/A TYR 195.A OH GLU 35.A OE2 no hydrogen 2.684 N/A TYR 195.A OH THR 293.A OG1 no hydrogen 2.805 N/A SER 196.A N THR 270.A O no hydrogen 3.024 N/A SER 196.A OG THR 270.A OG1 no hydrogen 2.497 N/A ILE 197.A N THR 289.A O no hydrogen 3.083 N/A ASN 198.A N MET 268.A O no hydrogen 2.732 N/A TYR 199.A N GLU 287.A O no hydrogen 2.786 N/A LEU 200.A N GLU 266.A O no hydrogen 3.381 N/A HIS 201.A N CYS 285.A O no hydrogen 2.678 N/A HIS 201.A ND1 TYR 59.A OH no hydrogen 2.964 N/A HIS 201.A NE2 GLU 287.A OE2 no hydrogen 2.667 N/A GLU 204.A N PHE 283.A O no hydrogen 2.933 N/A LYS 206.A N GLN 262.A O no hydrogen 2.953 N/A LYS 206.A NZ ASN 280.A OD1 no hydrogen 2.784 N/A SER 207.A N PHE 279.A O no hydrogen 2.774 N/A SER 207.A OG THR 261.A OG1 no hydrogen 2.877 N/A TRP 208.A N VAL 260.A O no hydrogen 2.704 N/A TYR 209.A N ALA 277.A O no hydrogen 2.708 N/A TYR 209.A OH GLU 118.A OE2 no hydrogen 2.470 N/A SER 210.A N ASP 258.A O no hydrogen 3.053 N/A VAL 211.A N TYR 275.A O no hydrogen 2.851 N/A HIS 215.A N PRO 212.A O no hydrogen 2.756 N/A GLY 216.A N PRO 213.A O no hydrogen 3.029 N/A LYS 217.A NZ GLU 220.A OE1 no hydrogen 3.360 N/A LYS 217.A NZ TYR 273.A OH no hydrogen 3.164 N/A ARG 218.A N HIS 215.A O no hydrogen 2.929 N/A ARG 218.A NH2 HIS 215.A ND1 no hydrogen 3.100 N/A LEU 219.A N HIS 215.A O no hydrogen 3.277 N/A GLU 220.A N GLY 216.A O no hydrogen 3.094 N/A ARG 221.A N LYS 217.A O no hydrogen 3.070 N/A LEU 222.A N ARG 218.A O no hydrogen 3.176 N/A ALA 223.A N LEU 219.A O no hydrogen 2.956 N/A LYS 224.A N GLU 220.A O no hydrogen 2.736 N/A GLY 225.A N ARG 221.A O no hydrogen 3.120 N/A PHE 226.A N LEU 222.A O no hydrogen 2.863 N/A PHE 227.A N ALA 223.A O no hydrogen 2.847 N/A ALA 231.A N PHE 227.A O no hydrogen 3.114 N/A GLN 232.A N PRO 228.A O no hydrogen 3.203 N/A GLN 232.A N GLY 229.A O no hydrogen 3.194 N/A GLN 232.A NE2 PRO 228.A O no hydrogen 3.262 N/A SER 233.A N GLY 229.A O no hydrogen 3.254 N/A SER 233.A OG GLY 229.A O no hydrogen 3.092 N/A CYS 234.A N SER 230.A O no hydrogen 3.043 N/A CYS 234.A SG HIS 240.A NE2 no hydrogen 3.497 N/A GLU 235.A N SER 307.A OG no hydrogen 2.908 N/A ARG 239.A N ALA 236.A O no hydrogen 3.044 N/A ARG 239.A NE VAL 304.A O no hydrogen 2.725 N/A ARG 239.A NH1 GLU 190.A O no hydrogen 2.925 N/A ARG 239.A NH2 ASP 193.A OD1 no hydrogen 2.992 N/A ARG 239.A NH2 VAL 304.A O no hydrogen 2.941 N/A HIS 240.A N PHE 237.A O no hydrogen 3.105 N/A LYS 241.A N LEU 238.A O no hydrogen 3.040 N/A LEU 244.A N PHE 82.A O no hydrogen 2.915 N/A SER 246.A N GLY 80.A O no hydrogen 2.926 N/A MET 249.A N SER 246.A OG no hydrogen 3.256 N/A LEU 250.A N SER 246.A O no hydrogen 3.182 N/A LYS 251.A N PRO 247.A O no hydrogen 2.871 N/A LYS 252.A N LEU 248.A O no hydrogen 3.045 N/A TYR 253.A N MET 249.A O no hydrogen 3.305 N/A TYR 253.A N LEU 250.A O no hydrogen 3.211 N/A GLY 254.A N LYS 251.A O no hydrogen 2.982 N/A ILE 255.A N LEU 250.A O no hydrogen 2.992 N/A ASP 258.A N SER 210.A O no hydrogen 2.978 N/A LYS 259.A N ASP 258.A OD1 no hydrogen 2.904 N/A LYS 259.A NZ GLU 118.A OE1 no hydrogen 3.110 N/A LYS 259.A NZ GLU 118.A OE2 no hydrogen 3.116 N/A VAL 260.A N TRP 208.A O no hydrogen 3.058 N/A THR 261.A OG1 SER 207.A OG no hydrogen 2.877 N/A GLN 262.A N LYS 206.A O no hydrogen 2.753 N/A GLN 262.A NE2 ASN 198.A OD1 no hydrogen 3.428 N/A GLU 263.A N GLU 266.A OE2 no hydrogen 2.814 N/A GLY 265.A N LEU 200.A O no hydrogen 2.768 N/A GLU 266.A N GLU 263.A O no hydrogen 3.174 N/A PHE 267.A N VAL 47.A O no hydrogen 2.934 N/A MET 268.A N ASN 198.A O no hydrogen 2.733 N/A ILE 269.A N ALA 45.A O no hydrogen 2.863 N/A THR 270.A N SER 196.A O no hydrogen 2.983 N/A THR 270.A OG1 SER 196.A OG no hydrogen 2.497 N/A PHE 271.A N GLY 43.A O no hydrogen 2.954 N/A TYR 273.A OH GLU 220.A OE2 no hydrogen 2.533 N/A GLY 274.A N PHE 271.A O no hydrogen 2.937 N/A TYR 275.A OH GLU 220.A OE2 no hydrogen 2.395 N/A HIS 276.A N HIS 188.A O no hydrogen 3.010 N/A HIS 276.A ND1 GLY 274.A O no hydrogen 2.841 N/A ALA 277.A N TYR 209.A O no hydrogen 3.006 N/A GLY 278.A N PHE 185.A O no hydrogen 2.933 N/A PHE 279.A N SER 207.A O no hydrogen 3.007 N/A ASN 280.A N THR 183.A O no hydrogen 2.924 N/A ASN 280.A ND2 TYR 132.A OH no hydrogen 3.333 N/A ASN 280.A ND2 THR 183.A OG1 no hydrogen 2.739 N/A HIS 281.A N PRO 205.A O no hydrogen 2.936 N/A ASN 284.A N GLY 179.A O no hydrogen 3.257 N/A ASN 284.A ND2 GLU 204.A O no hydrogen 2.905 N/A ASN 284.A ND2 PRO 205.A O no hydrogen 3.634 N/A ASN 284.A ND2 ASN 280.A OD1 no hydrogen 3.131 N/A CYS 285.A N PHE 202.A O no hydrogen 2.895 N/A ALA 286.A N TYR 177.A O no hydrogen 2.877 N/A GLU 287.A N TYR 199.A O no hydrogen 2.751 N/A SER 288.A N TYR 175.A O no hydrogen 2.933 N/A THR 289.A N ILE 197.A O no hydrogen 3.292 N/A THR 289.A OG1 VAL 171.A O no hydrogen 3.198 N/A THR 289.A OG1 THR 173.A O no hydrogen 2.963 N/A ASN 290.A N VAL 171.A O no hydrogen 3.087 N/A ASN 290.A ND2 GLU 190.A OE2 no hydrogen 2.921 N/A ASN 290.A ND2 TYR 195.A O no hydrogen 2.856 N/A PHE 291.A N TYR 195.A O no hydrogen 3.052 N/A THR 293.A OG1 TYR 195.A OH no hydrogen 2.805 N/A ARG 295.A NE GLU 35.A OE1 no hydrogen 2.966 N/A ARG 295.A NE GLU 35.A OE2 no hydrogen 3.402 N/A ARG 295.A NH2 GLU 35.A OE2 no hydrogen 3.080 N/A TRP 296.A N THR 293.A O no hydrogen 2.980 N/A TRP 296.A NE1 MET 192.A O no hydrogen 2.732 N/A ILE 297.A N ARG 294.A O no hydrogen 3.246 N/A TYR 299.A OH HIS 343.A ND1 no hydrogen 2.867 N/A GLY 300.A N TRP 296.A O no hydrogen 2.960 N/A LYS 301.A N ILE 297.A O no hydrogen 3.058 N/A LYS 301.A NZ GLU 298.A OE1 no hydrogen 3.444 N/A LYS 301.A NZ GLU 298.A OE2 no hydrogen 2.871 N/A LYS 301.A NZ GLN 325.A OE1 no hydrogen 2.670 N/A LYS 301.A NZ ASP 337.A OD2 no hydrogen 2.788 N/A GLN 302.A N GLU 298.A O no hydrogen 3.129 N/A GLN 302.A N TYR 299.A O no hydrogen 3.274 N/A GLN 302.A NE2 GLU 298.A OE1 no hydrogen 2.852 N/A GLN 302.A NE2 THR 339.A O no hydrogen 2.696 N/A CYS 306.A SG HIS 240.A NE2 no hydrogen 3.688 N/A CYS 308.A SG HIS 240.A NE2 no hydrogen 3.506 N/A PHE 320.A N MET 317.A O no hydrogen 2.918 N/A VAL 321.A N MET 317.A O no hydrogen 3.107 N/A ARG 322.A N ASP 318.A O no hydrogen 2.931 N/A LYS 323.A N VAL 319.A O no hydrogen 3.082 N/A PHE 324.A N PHE 320.A O no hydrogen 2.861 N/A GLN 325.A N VAL 321.A O no hydrogen 2.796 N/A GLN 325.A NE2 GLU 298.A OE2 no hydrogen 3.229 N/A ARG 328.A N GLN 325.A O no hydrogen 2.962 N/A TYR 329.A OH ASP 318.A OD1 no hydrogen 2.455 N/A TRP 332.A N ARG 328.A O no hydrogen 2.791 N/A LYS 333.A N TYR 329.A O no hydrogen 2.823 N/A LYS 333.A NZ ASP 318.A OD2 no hydrogen 2.483 N/A ALA 334.A N LYS 330.A O no hydrogen 3.262 N/A GLY 335.A N TRP 332.A O no hydrogen 2.913 N/A LYS 336.A N LEU 331.A O no hydrogen 2.922 N/A THR 339.A N ASP 337.A OD1 no hydrogen 3.164 N/A THR 339.A OG1 ASP 337.A OD1 no hydrogen 2.702 N/A HIS 343.A ND1 TYR 299.A OH no hydrogen 2.867 N/A THR 344.A N ASP 342.A OD1 no hydrogen 2.918 N/A THR 344.A OG1 SER 5.A OG no hydrogen 3.050 N/A THR 344.A OG1 ASP 342.A OD1 no hydrogen 2.777 N/A THR 344.A OG1 ASP 342.A OD2 no hydrogen 3.349 N/A LEU 345.A N ASP 342.A O no hydrogen 3.372 N/A