Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 3cif_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ALA 2.A N ASP 25.A O no hydrogen 3.142 N/A THR 3.A N GLN 91.A OE1 no hydrogen 2.990 N/A THR 3.A OG1 GLY 89.A O no hydrogen 2.641 N/A LEU 4.A N THR 27.A O no hydrogen 2.690 N/A GLY 5.A N ILE 92.A O no hydrogen 2.796 N/A ILE 6.A N ALA 30.A O no hydrogen 2.961 N/A ASN 7.A N CYS 94.A O no hydrogen 2.837 N/A ASN 7.A ND2 GLU 95.A OE1 no hydrogen 2.796 N/A GLY 8.A N ASN 32.A O no hydrogen 2.925 N/A PHE 9.A N ASP 33.A OD2 no hydrogen 2.814 N/A ARG 11.A NE GLU 319.A OE2 no hydrogen 2.758 N/A ARG 11.A NH1 ASP 48.A OD2 no hydrogen 2.875 N/A ARG 11.A NH2 ASP 48.A OD1 no hydrogen 2.980 N/A ARG 11.A NH2 ASP 48.A OD2 no hydrogen 3.342 N/A ARG 11.A NH2 GLU 319.A OE1 no hydrogen 2.885 N/A ARG 11.A NH2 GLU 319.A OE2 no hydrogen 3.424 N/A ARG 14.A N GLY 10.A O no hydrogen 2.855 N/A ARG 14.A NH1 PHE 9.A O no hydrogen 2.820 N/A LEU 15.A N ARG 11.A O no hydrogen 3.282 N/A VAL 16.A N ILE 12.A O no hydrogen 2.808 N/A LEU 17.A N GLY 13.A O no hydrogen 3.221 N/A ARG 18.A N ARG 14.A O no hydrogen 2.993 N/A ARG 18.A NH1 HIS 51.A O no hydrogen 3.309 N/A ARG 18.A NH1 GLY 52.A O no hydrogen 3.047 N/A ARG 18.A NH2 LEU 45.A O no hydrogen 2.914 N/A ARG 18.A NH2 GLY 52.A O no hydrogen 2.869 N/A ALA 19.A N LEU 15.A O no hydrogen 2.908 N/A CYS 20.A N VAL 16.A O no hydrogen 2.900 N/A CYS 20.A SG VAL 16.A O no hydrogen 3.317 N/A MET 21.A N LEU 17.A O no hydrogen 2.927 N/A GLU 22.A N ALA 19.A O no hydrogen 3.239 N/A ARG 23.A N CYS 20.A O no hydrogen 2.942 N/A ARG 23.A NE ASP 25.A OD1 no hydrogen 3.071 N/A ARG 23.A NH1 ASP 328.A OD1 no hydrogen 2.535 N/A ARG 23.A NH2 ASP 25.A OD1 no hydrogen 3.502 N/A ARG 23.A NH2 ASP 25.A OD2 no hydrogen 3.074 N/A THR 27.A N ALA 2.A O no hydrogen 2.901 N/A VAL 29.A N LEU 4.A O no hydrogen 2.961 N/A ILE 31.A N LYS 73.A O no hydrogen 2.826 N/A ASN 32.A N ILE 6.A O no hydrogen 2.832 N/A ASN 32.A ND2 ASN 7.A OD1 no hydrogen 2.776 N/A ASN 32.A ND2 ALA 77.A O no hydrogen 2.779 N/A ASP 33.A N PHE 75.A O no hydrogen 3.133 N/A PHE 35.A N ASP 33.A OD1 no hydrogen 3.185 N/A MET 36.A N ASP 33.A O no hydrogen 3.420 N/A TYR 40.A N ASP 37.A OD1 no hydrogen 2.947 N/A MET 41.A N ASP 37.A O no hydrogen 2.850 N/A ALA 42.A N VAL 38.A O no hydrogen 3.089 N/A TYR 43.A N GLU 39.A O no hydrogen 3.128 N/A LEU 44.A N TYR 40.A O no hydrogen 2.985 N/A LEU 45.A N MET 41.A O no hydrogen 3.046 N/A LYS 46.A N ALA 42.A O no hydrogen 2.972 N/A LYS 46.A NZ VAL 58.A O no hydrogen 3.263 N/A TYR 47.A N TYR 43.A O no hydrogen 3.069 N/A VAL 50.A N ASP 48.A OD1 no hydrogen 3.047 N/A HIS 51.A N ASP 48.A OD1 no hydrogen 2.945 N/A HIS 51.A NE2 GLU 319.A OE1 no hydrogen 2.734 N/A GLY 52.A N ASP 48.A O no hydrogen 3.280 N/A PHE 54.A N LYS 46.A O no hydrogen 2.909 N/A THR 57.A N ASN 68.A OD1 no hydrogen 2.900 N/A GLU 59.A N CYS 66.A O no hydrogen 2.862 N/A SER 61.A N ASP 64.A O no hydrogen 2.818 N/A ASP 64.A N SER 61.A O no hydrogen 3.097 N/A LEU 65.A N VAL 72.A O no hydrogen 3.026 N/A CYS 66.A N GLU 59.A O no hydrogen 2.725 N/A ILE 67.A N LYS 70.A O no hydrogen 2.863 N/A ASN 68.A N THR 57.A O no hydrogen 3.005 N/A LYS 70.A N ILE 67.A O no hydrogen 3.024 N/A VAL 72.A N LEU 65.A O no hydrogen 2.773 N/A LYS 73.A N VAL 29.A O no hydrogen 2.829 N/A LYS 73.A NZ ASP 64.A OD2 no hydrogen 2.742 N/A VAL 74.A N ASP 64.A OD1 no hydrogen 3.094 N/A PHE 75.A N ILE 31.A O no hydrogen 2.868 N/A GLN 76.A NE2 MET 36.A O no hydrogen 2.787 N/A ALA 77.A N ASN 32.A OD1 no hydrogen 2.766 N/A ALA 81.A N ASP 79.A OD1 no hydrogen 3.165 N/A GLU 82.A N ASP 79.A O no hydrogen 3.081 N/A ILE 83.A N PRO 80.A O no hydrogen 3.305 N/A TRP 85.A N ILE 83.A O no hydrogen 3.005 N/A TRP 85.A NE1 HIS 109.A ND1 no hydrogen 2.957 N/A GLY 86.A N GLY 112.A O no hydrogen 2.874 N/A SER 88.A N PRO 84.A O no hydrogen 3.284 N/A SER 88.A OG PRO 84.A O no hydrogen 3.209 N/A GLY 89.A N GLY 86.A O no hydrogen 2.918 N/A ALA 90.A N TRP 85.A O no hydrogen 2.958 N/A GLN 91.A N THR 3.A O no hydrogen 3.317 N/A GLN 91.A N THR 3.A OG1 no hydrogen 2.921 N/A ILE 92.A N THR 3.A O no hydrogen 3.137 N/A VAL 93.A N LYS 116.A O no hydrogen 2.944 N/A CYS 94.A N GLY 5.A O no hydrogen 2.673 N/A CYS 94.A SG SER 96.A OG no hydrogen 3.507 N/A GLU 95.A N ILE 118.A O no hydrogen 2.792 N/A SER 96.A N ASN 7.A O no hydrogen 2.849 N/A SER 96.A OG ASN 7.A O no hydrogen 3.077 N/A SER 96.A OG GLY 8.A O no hydrogen 2.916 N/A THR 97.A N GLU 95.A OE2 no hydrogen 3.166 N/A THR 97.A OG1 GLU 95.A OE2 no hydrogen 2.633 N/A VAL 99.A N THR 97.A OG1 no hydrogen 3.051 N/A GLU 103.A N ASP 125.A OD2 no hydrogen 2.871 N/A LYS 105.A N THR 102.A OG1 no hydrogen 3.231 N/A ALA 106.A N THR 102.A O no hydrogen 2.814 N/A SER 107.A N GLU 103.A O no hydrogen 2.847 N/A SER 107.A OG GLU 103.A O no hydrogen 2.736 N/A SER 107.A OG GLU 104.A O no hydrogen 3.318 N/A LEU 108.A N LYS 105.A O no hydrogen 3.356 N/A HIS 109.A N ALA 106.A O no hydrogen 3.367 N/A HIS 109.A NE2 GLU 95.A OE1 no hydrogen 2.691 N/A LEU 110.A N SER 107.A O no hydrogen 2.996 N/A LYS 111.A N LEU 108.A O no hydrogen 3.176 N/A GLY 113.A N LEU 110.A O no hydrogen 3.213 N/A ALA 114.A N HIS 109.A O no hydrogen 3.315 N/A LYS 115.A N GLN 91.A O no hydrogen 2.840 N/A LYS 116.A N GLN 91.A O no hydrogen 3.176 N/A LYS 116.A NZ TYR 139.A OH no hydrogen 3.444 N/A LYS 116.A NZ PRO 141.A O no hydrogen 3.102 N/A LYS 116.A NZ PHE 144.A O no hydrogen 2.981 N/A LYS 116.A NZ ASN 145.A OD1 no hydrogen 2.768 N/A VAL 117.A N ASN 145.A O no hydrogen 2.863 N/A ILE 118.A N VAL 93.A O no hydrogen 2.879 N/A ILE 119.A N ILE 147.A O no hydrogen 2.845 N/A SER 120.A N GLU 95.A O no hydrogen 2.845 N/A SER 120.A OG GLU 95.A O no hydrogen 3.241 N/A LYS 124.A N THR 101.A O no hydrogen 2.917 N/A TYR 130.A N SER 148.A O no hydrogen 2.794 N/A VAL 131.A N ASN 135.A OD1 no hydrogen 2.796 N/A GLY 133.A N ASN 136.A OD1 no hydrogen 2.964 N/A VAL 134.A N VAL 131.A O no hydrogen 2.966 N/A ASN 135.A N VAL 131.A O no hydrogen 3.155 N/A ASN 135.A ND2 MET 129.A O no hydrogen 3.070 N/A GLU 138.A N ASN 135.A O no hydrogen 3.025 N/A TYR 139.A N ASN 136.A O no hydrogen 3.187 N/A SER 142.A N ASP 140.A OD1 no hydrogen 3.024 N/A SER 142.A OG ASP 140.A OD1 no hydrogen 2.674 N/A LYS 143.A N ASP 140.A O no hydrogen 2.938 N/A PHE 144.A N ASP 140.A O no hydrogen 3.207 N/A ILE 147.A N VAL 117.A O no hydrogen 2.876 N/A SER 148.A N PRO 128.A O no hydrogen 2.885 N/A SER 148.A OG ALA 121.A O no hydrogen 2.597 N/A ASN 149.A N ILE 119.A O no hydrogen 3.129 N/A ALA 150.A N SER 148.A OG no hydrogen 2.984 N/A SER 151.A OG THR 154.A OG1 no hydrogen 2.681 N/A THR 153.A OG1 TYR 316.A OH no hydrogen 2.668 N/A THR 154.A N SER 151.A OG no hydrogen 3.155 N/A THR 154.A OG1 SER 151.A OG no hydrogen 2.681 N/A ASN 155.A N SER 151.A O no hydrogen 2.954 N/A ASN 155.A ND2 ASN 149.A O no hydrogen 2.938 N/A ASN 155.A ND2 SER 151.A O no hydrogen 2.749 N/A CYS 156.A N SER 152.A O no hydrogen 2.974 N/A CYS 156.A N THR 153.A O no hydrogen 3.187 N/A CYS 156.A SG SER 295.A OG no hydrogen 3.569 N/A CYS 156.A SG SER 314.A O no hydrogen 3.511 N/A LEU 157.A N THR 153.A O no hydrogen 2.773 N/A ALA 158.A N THR 154.A O no hydrogen 2.836 N/A ALA 161.A N LEU 157.A O no hydrogen 2.832 N/A LYS 162.A N ALA 158.A O no hydrogen 2.889 N/A LYS 162.A NZ ASP 166.A OD2 no hydrogen 2.957 N/A ILE 163.A N PRO 159.A O no hydrogen 3.086 N/A ILE 164.A N LEU 160.A O no hydrogen 3.097 N/A ASN 165.A N ALA 161.A O no hydrogen 2.879 N/A ASP 166.A N LYS 162.A O no hydrogen 2.824 N/A LYS 167.A N ILE 163.A O no hydrogen 3.107 N/A PHE 168.A N ILE 164.A O no hydrogen 2.798 N/A GLY 169.A N ILE 164.A O no hydrogen 2.942 N/A ILE 170.A N ASN 165.A OD1 no hydrogen 2.881 N/A VAL 171.A N LYS 250.A O no hydrogen 2.920 N/A GLY 173.A N LYS 229.A O no hydrogen 2.805 N/A LEU 174.A N THR 248.A O no hydrogen 2.749 N/A MET 175.A N THR 231.A O no hydrogen 3.091 N/A THR 176.A N ASP 246.A O no hydrogen 2.876 N/A THR 177.A N MET 233.A O no hydrogen 3.072 N/A THR 177.A OG1 TYR 316.A OH no hydrogen 2.655 N/A VAL 178.A N VAL 244.A O no hydrogen 2.963 N/A HIS 179.A N ILE 235.A O no hydrogen 2.844 N/A HIS 179.A ND1 SER 180.A O no hydrogen 2.594 N/A SER 180.A N SER 243.A OG no hydrogen 3.167 N/A SER 180.A OG THR 239.A O no hydrogen 3.152 N/A SER 180.A OG THR 239.A OG1 no hydrogen 2.675 N/A SER 180.A OG VAL 242.A O no hydrogen 2.710 N/A LEU 181.A N THR 239.A O no hydrogen 3.026 N/A THR 182.A N GLN 185.A OE1 no hydrogen 3.248 N/A THR 182.A OG1 ASN 184.A OD1 no hydrogen 2.473 N/A GLN 185.A N THR 182.A O no hydrogen 3.060 N/A GLY 190.A N GLY 201.A O no hydrogen 2.816 N/A SER 192.A OG ASP 197.A O no hydrogen 2.771 N/A TRP 198.A NE1 GLY 195.A O no hydrogen 2.924 N/A ALA 200.A N ASP 197.A O no hydrogen 3.281 N/A GLY 201.A N TRP 198.A O no hydrogen 3.043 N/A ARG 202.A N ARG 199.A O no hydrogen 3.154 N/A ARG 202.A NE ASP 189.A OD1 no hydrogen 3.075 N/A CYS 203.A N ASP 189.A OD1 no hydrogen 2.847 N/A CYS 203.A SG THR 187.A O no hydrogen 3.326 N/A CYS 203.A SG ASN 206.A OD1 no hydrogen 3.196 N/A ALA 204.A N LEU 186.A O no hydrogen 2.990 N/A ASN 207.A ND2 CYS 203.A O no hydrogen 2.795 N/A ILE 209.A N ARG 236.A O no hydrogen 2.903 N/A ALA 211.A N ALA 234.A O no hydrogen 2.748 N/A ALA 215.A N THR 213.A OG1 no hydrogen 3.331 N/A ALA 216.A N THR 213.A O no hydrogen 3.299 N/A ALA 218.A N GLY 214.A O no hydrogen 3.106 N/A VAL 219.A N ALA 215.A O no hydrogen 3.246 N/A LYS 221.A N ALA 218.A O no hydrogen 2.955 N/A VAL 222.A N ALA 218.A O no hydrogen 3.012 N/A ILE 223.A N VAL 219.A O no hydrogen 2.869 N/A LEU 226.A N ILE 223.A O no hydrogen 2.919 N/A ASN 227.A N PRO 224.A O no hydrogen 3.098 N/A LYS 229.A N LEU 226.A O no hydrogen 2.902 N/A THR 231.A OG1 ALA 216.A O no hydrogen 3.520 N/A MET 233.A N MET 175.A O no hydrogen 3.199 N/A ALA 234.A N ALA 211.A O no hydrogen 2.869 N/A ILE 235.A N THR 177.A O no hydrogen 2.753 N/A ARG 236.A N ILE 209.A O no hydrogen 2.677 N/A ARG 236.A NH1 THR 182.A OG1 no hydrogen 2.675 N/A ARG 236.A NH1 GLN 185.A OE1 no hydrogen 3.094 N/A VAL 237.A N HIS 179.A O no hydrogen 2.894 N/A THR 239.A OG1 SER 180.A OG no hydrogen 2.675 N/A VAL 242.A N ASN 318.A OD1 no hydrogen 2.876 N/A SER 243.A N TYR 316.A O no hydrogen 2.816 N/A SER 243.A OG ASN 318.A OD1 no hydrogen 3.015 N/A VAL 244.A N VAL 178.A O no hydrogen 2.967 N/A VAL 245.A N SER 314.A O no hydrogen 2.772 N/A ASP 246.A N THR 176.A O no hydrogen 2.669 N/A LEU 247.A N LEU 312.A O no hydrogen 2.859 N/A THR 248.A N LEU 174.A O no hydrogen 2.869 N/A CYS 249.A N VAL 310.A O no hydrogen 3.061 N/A LYS 250.A N GLU 172.A O no hydrogen 2.789 N/A LYS 250.A NZ SER 308.A OG no hydrogen 3.344 N/A LEU 251.A N SER 308.A O no hydrogen 2.760 N/A ALA 252.A N GLY 169.A O no hydrogen 2.900 N/A LYS 253.A N PHE 168.A O no hydrogen 3.184 N/A ALA 255.A N ASP 307.A O no hydrogen 2.670 N/A SER 256.A N GLU 259.A OE1 no hydrogen 3.115 N/A GLU 259.A N SER 256.A OG no hydrogen 3.302 N/A ILE 260.A N SER 256.A O no hydrogen 3.057 N/A TYR 261.A N ILE 257.A O no hydrogen 2.800 N/A GLN 262.A N GLU 258.A O no hydrogen 2.883 N/A GLN 262.A NE2 GLU 258.A OE2 no hydrogen 2.785 N/A ALA 263.A N GLU 259.A O no hydrogen 3.048 N/A VAL 264.A N ILE 260.A O no hydrogen 3.031 N/A LYS 265.A N TYR 261.A O no hydrogen 2.886 N/A GLU 266.A N GLN 262.A O no hydrogen 2.932 N/A ALA 267.A N ALA 263.A O no hydrogen 3.256 N/A SER 268.A N VAL 264.A O no hydrogen 2.871 N/A SER 268.A OG MET 276.A O no hydrogen 2.686 N/A ASN 269.A N LYS 265.A O no hydrogen 3.065 N/A GLY 270.A N ALA 267.A O no hydrogen 3.119 N/A MET 272.A N ALA 267.A O no hydrogen 2.813 N/A ILE 275.A N MET 272.A O no hydrogen 2.998 N/A MET 276.A N MET 272.A O no hydrogen 2.926 N/A GLY 277.A N SER 295.A O no hydrogen 2.650 N/A THR 279.A N LEU 297.A O no hydrogen 2.901 N/A SER 280.A OG TYR 261.A OH no hydrogen 3.357 N/A ASP 281.A N THR 279.A OG1 no hydrogen 3.080 N/A VAL 283.A N ASP 281.A O no hydrogen 2.864 N/A VAL 284.A N ASP 287.A OD2 no hydrogen 2.984 N/A ASP 287.A N VAL 284.A O no hydrogen 3.062 N/A PHE 288.A N SER 285.A O no hydrogen 2.979 N/A ILE 289.A N THR 286.A O no hydrogen 3.255 N/A GLY 290.A N ASP 317.A OD2 no hydrogen 2.750 N/A CYS 291.A N PHE 288.A O no hydrogen 2.882 N/A SER 294.A N ILE 275.A O no hydrogen 2.835 N/A SER 295.A N ILE 275.A O no hydrogen 3.209 N/A SER 295.A OG CYS 156.A O no hydrogen 2.870 N/A SER 295.A OG SER 314.A OG no hydrogen 2.614 N/A ILE 296.A N TRP 315.A O no hydrogen 2.972 N/A LEU 297.A N GLY 277.A O no hydrogen 2.987 N/A ASP 298.A N ILE 313.A O no hydrogen 2.788 N/A LYS 299.A N THR 279.A O no hydrogen 3.055 N/A LYS 299.A NZ GLU 258.A OE1 no hydrogen 2.799 N/A ASN 300.A ND2 SER 280.A O no hydrogen 2.838 N/A ASN 300.A ND2 ASP 282.A OD1 no hydrogen 3.127 N/A ALA 301.A N ASP 298.A O no hydrogen 3.219 N/A ALA 301.A N ASP 298.A OD1 no hydrogen 3.172 N/A CYS 302.A N ASP 298.A O no hydrogen 3.271 N/A CYS 302.A N LYS 299.A O no hydrogen 3.327 N/A CYS 302.A SG ASP 298.A O no hydrogen 3.275 N/A ILE 303.A N LYS 311.A O no hydrogen 2.975 N/A LEU 305.A N PHE 309.A O no hydrogen 2.994 N/A SER 308.A N ASN 306.A OD1 no hydrogen 3.058 N/A SER 308.A OG ASN 306.A OD1 no hydrogen 3.384 N/A VAL 310.A N CYS 249.A O no hydrogen 3.171 N/A LYS 311.A N ILE 303.A O no hydrogen 2.702 N/A LYS 311.A NZ ASP 246.A OD1 no hydrogen 3.015 N/A LYS 311.A NZ ASP 246.A OD2 no hydrogen 3.436 N/A LYS 311.A NZ THR 248.A OG1 no hydrogen 2.896 N/A LEU 312.A N LEU 247.A O no hydrogen 2.718 N/A SER 314.A N VAL 245.A O no hydrogen 3.010 N/A SER 314.A OG SER 295.A OG no hydrogen 2.614 N/A TRP 315.A N ILE 296.A O no hydrogen 2.848 N/A TRP 315.A NE1 ASP 298.A OD2 no hydrogen 2.812 N/A TYR 316.A N SER 243.A O no hydrogen 2.998 N/A TYR 316.A OH THR 153.A OG1 no hydrogen 2.668 N/A TYR 316.A OH THR 177.A OG1 no hydrogen 2.655 N/A GLU 319.A N ASP 317.A OD1 no hydrogen 2.973 N/A SER 320.A N ASP 317.A OD1 no hydrogen 2.860 N/A SER 320.A OG ASP 317.A OD2 no hydrogen 3.347 N/A GLY 321.A N ASP 317.A O no hydrogen 2.883 N/A TYR 322.A OH ALA 150.A O no hydrogen 2.648 N/A SER 323.A N GLU 319.A O no hydrogen 3.195 N/A SER 323.A OG GLU 319.A O no hydrogen 2.722 N/A ASN 324.A N SER 320.A O no hydrogen 3.174 N/A ASN 324.A ND2 SER 320.A O no hydrogen 2.887 N/A ARG 325.A N GLY 321.A O no hydrogen 3.124 N/A ARG 325.A NE ASP 328.A OD2 no hydrogen 2.719 N/A ARG 325.A NH1 LYS 292.A O no hydrogen 2.771 N/A ARG 325.A NH1 SER 294.A OG no hydrogen 2.994 N/A ARG 325.A NH2 LYS 292.A O no hydrogen 3.131 N/A ARG 325.A NH2 ASP 328.A OD2 no hydrogen 3.024 N/A LEU 326.A N TYR 322.A O no hydrogen 2.909 N/A VAL 327.A N SER 323.A O no hydrogen 3.153 N/A ASP 328.A N ASN 324.A O no hydrogen 2.816 N/A LEU 329.A N ARG 325.A O no hydrogen 2.760 N/A ALA 330.A N LEU 326.A O no hydrogen 2.890 N/A VAL 331.A N VAL 327.A O no hydrogen 3.009 N/A TYR 332.A N ASP 328.A O no hydrogen 2.920 N/A VAL 333.A N LEU 329.A O no hydrogen 2.796 N/A ALA 334.A N ALA 330.A O no hydrogen 2.955 N/A SER 335.A N VAL 331.A O no hydrogen 2.989 N/A SER 335.A OG TYR 332.A O no hydrogen 2.639 N/A ARG 336.A N TYR 332.A O no hydrogen 3.196 N/A ARG 336.A N VAL 333.A O no hydrogen 3.211 N/A ARG 336.A NH1 TYR 139.A O no hydrogen 2.726 N/A ARG 336.A NH1 TYR 332.A OH no hydrogen 3.019 N/A GLY 337.A N ALA 334.A O no hydrogen 3.156 N/A