Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 3im2_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): THR 3.A N ILE 1.A O no hydrogen 2.753 N/A THR 3.A OG1 ILE 1.A O no hydrogen 3.475 N/A SER 5.A N ALA 124.A O no hydrogen 3.215 N/A LEU 8.A N SER 5.A O no hydrogen 3.257 N/A ILE 9.A N ASN 6.A O no hydrogen 3.286 N/A SER 11.A OG ASP 120.A OD2 no hydrogen 2.662 N/A TYR 13.A N SER 11.A OG no hydrogen 3.393 N/A SER 16.A N GLU 45.A OE2 no hydrogen 2.923 N/A SER 16.A OG THR 19.A OG1 no hydrogen 3.064 N/A SER 16.A OG GLU 45.A OE2 no hydrogen 3.174 N/A THR 19.A N SER 16.A OG no hydrogen 2.972 N/A THR 19.A OG1 SER 16.A OG no hydrogen 3.064 N/A THR 19.A OG1 GLU 45.A OE1 no hydrogen 2.627 N/A THR 19.A OG1 GLU 45.A OE2 no hydrogen 3.412 N/A ILE 20.A N SER 16.A O no hydrogen 3.047 N/A GLN 21.A N PHE 17.A O no hydrogen 2.839 N/A SER 22.A N PHE 18.A O no hydrogen 3.040 N/A PHE 23.A N THR 19.A O no hydrogen 2.785 N/A VAL 24.A N ILE 20.A O no hydrogen 2.944 N/A SER 25.A N.A GLN 21.A O no hydrogen 3.166 N/A SER 25.A N.B GLN 21.A O no hydrogen 3.175 N/A SER 25.A OG.A GLN 21.A O no hydrogen 3.020 N/A SER 25.A OG.B GLN 21.A O no hydrogen 3.393 N/A SER 25.A OG.B SER 22.A O no hydrogen 3.062 N/A SER 26.A N SER 22.A O no hydrogen 3.038 N/A SER 26.A N PHE 23.A O no hydrogen 3.115 N/A SER 26.A OG SER 22.A O no hydrogen 2.863 N/A LEU 27.A N PHE 23.A O no hydrogen 3.039 N/A SER 28.A N SER 31.A OG no hydrogen 3.005 N/A SER 28.A OG THR 30.A OG1 no hydrogen 3.025 N/A THR 30.A N SER 28.A OG no hydrogen 3.081 N/A THR 30.A OG1 SER 28.A OG no hydrogen 3.025 N/A SER 31.A N SER 28.A O no hydrogen 3.297 N/A SER 31.A OG SER 28.A O no hydrogen 3.297 N/A THR 32.A N ASN 35.A OD1 no hydrogen 3.109 N/A ASN 35.A N THR 32.A OG1 no hydrogen 3.241 N/A MET 36.A N THR 32.A O no hydrogen 2.992 N/A LEU 37.A N LEU 33.A O no hydrogen 2.941 N/A TYR 38.A N LYS 34.A O no hydrogen 3.048 N/A VAL 39.A N ASN 35.A O no hydrogen 2.855 N/A LEU 40.A N MET 36.A O no hydrogen 2.867 N/A SER 41.A N.A LEU 37.A O no hydrogen 3.045 N/A SER 41.A N.B LEU 37.A O no hydrogen 3.051 N/A SER 41.A N.B TYR 38.A O no hydrogen 2.974 N/A SER 41.A OG.A TYR 38.A O no hydrogen 2.543 N/A SER 41.A OG.B LEU 37.A O no hydrogen 2.999 N/A THR 42.A N VAL 39.A O no hydrogen 3.049 N/A THR 42.A OG1 VAL 39.A O no hydrogen 2.622 N/A ALA 43.A N LEU 40.A O no hydrogen 3.238 N/A PHE 46.A N ALA 43.A O no hydrogen 3.111 N/A GLU 47.A N VAL 44.A O no hydrogen 2.997 N/A VAL 49.A N PHE 46.A O no hydrogen 2.900 N/A ARG 52.A N.A ASP 55.A OD2 no hydrogen 2.994 N/A ARG 52.A N.B ASP 55.A OD2 no hydrogen 3.000 N/A ARG 52.A NH1.A ASP 103.A OD2 no hydrogen 2.764 N/A ARG 52.A NH2.A ASP 103.A OD1 no hydrogen 2.931 N/A ASP 55.A N ARG 52.A O.A no hydrogen 3.224 N/A ASP 55.A N ARG 52.A O.B no hydrogen 2.958 N/A LEU 58.A N GLY 54.A O no hydrogen 3.135 N/A LEU 59.A N ASP 55.A O no hydrogen 2.830 N/A VAL 60.A N ARG 56.A O.A no hydrogen 2.926 N/A VAL 60.A N ARG 56.A O.B no hydrogen 2.969 N/A LYS 61.A N ALA 57.A O no hydrogen 3.289 N/A LEU 62.A N LEU 58.A O no hydrogen 3.034 N/A SER 63.A N LEU 59.A O no hydrogen 2.841 N/A SER 63.A OG VAL 60.A O no hydrogen 2.615 N/A LYS 64.A N LYS 61.A O no hydrogen 3.251 N/A ARG 65.A N LEU 62.A O no hydrogen 3.110 N/A LEU 66.A N SER 63.A O no hydrogen 3.074 N/A LEU 68.A N GLN 88.A OE1 no hydrogen 3.013 N/A GLY 77.A N SER 75.A OG no hydrogen 3.186 N/A SER 78.A OG.B SER 80.A OG no hydrogen 3.146 N/A SER 80.A OG SER 78.A OG.B no hydrogen 3.146 N/A PHE 81.A N SER 78.A O.A no hydrogen 3.323 N/A PHE 81.A N SER 78.A O.B no hydrogen 3.207 N/A LYS 82.A NZ PRO 50.A O no hydrogen 2.738 N/A LYS 82.A NZ ASP 55.A OD2 no hydrogen 2.666 N/A LYS 82.A NZ ASP 103.A OD2 no hydrogen 2.801 N/A VAL 83.A N VAL 79.A O no hydrogen 2.957 N/A PHE 84.A N SER 80.A O no hydrogen 2.930 N/A LEU 85.A N PHE 81.A O no hydrogen 3.300 N/A LEU 86.A N LYS 82.A O no hydrogen 2.912 N/A LEU 87.A N VAL 83.A O no hydrogen 3.126 N/A GLN 88.A NE2 LEU 68.A O no hydrogen 2.879 N/A GLN 88.A NE2 PHE 84.A O no hydrogen 3.613 N/A ALA 89.A N LEU 85.A O no hydrogen 2.993 N/A TYR 90.A N LEU 86.A O no hydrogen 2.897 N/A TYR 90.A OH LEU 140.A O no hydrogen 2.885 N/A PHE 91.A N LEU 87.A O no hydrogen 3.058 N/A SER 92.A N GLN 88.A O no hydrogen 2.861 N/A SER 92.A OG GLN 88.A O no hydrogen 3.227 N/A ARG 93.A N TYR 90.A O no hydrogen 3.130 N/A ARG 93.A NE GLY 143.A O no hydrogen 2.833 N/A ARG 93.A NH2 GLN 142.A O no hydrogen 3.054 N/A LEU 94.A N ALA 89.A O no hydrogen 2.981 N/A GLN 101.A N PRO 97.A O no hydrogen 2.887 N/A GLN 101.A NE2 LEU 96.A O no hydrogen 2.802 N/A ASN 102.A N VAL 98.A O no hydrogen 2.969 N/A ASP 103.A N ASP 99.A O no hydrogen 3.185 N/A LEU 104.A N PHE 100.A O no hydrogen 2.918 N/A LYS 105.A N GLN 101.A O no hydrogen 3.156 N/A ASP 106.A N ASN 102.A O no hydrogen 3.263 N/A ILE 107.A N ASP 103.A O no hydrogen 2.903 N/A LEU 108.A N LEU 104.A O no hydrogen 2.866 N/A GLU 109.A N LYS 105.A O no hydrogen 3.168 N/A LYS 110.A N.A ILE 107.A O no hydrogen 2.921 N/A LYS 110.A N.B ILE 107.A O no hydrogen 2.896 N/A LYS 110.A NZ.A GLU 45.A O no hydrogen 3.093 N/A LYS 110.A NZ.B SER 48.A OG no hydrogen 2.740 N/A LYS 110.A NZ.B ASP 106.A O no hydrogen 3.308 N/A ILE 115.A N VAL 111.A O no hydrogen 2.930 N/A ASN 116.A N VAL 112.A O no hydrogen 3.158 N/A ASN 116.A ND2 VAL 112.A O no hydrogen 2.932 N/A VAL 117.A N PRO 113.A O no hydrogen 3.113 N/A VAL 118.A N LEU 114.A O no hydrogen 3.132 N/A VAL 119.A N ILE 115.A O no hydrogen 3.065 N/A ASP 120.A N ASN 116.A O no hydrogen 3.010 N/A ILE 121.A N VAL 117.A O no hydrogen 2.940 N/A LEU 122.A N VAL 118.A O no hydrogen 3.153 N/A SER 123.A N VAL 119.A O no hydrogen 2.919 N/A SER 123.A OG LEU 8.A O no hydrogen 2.731 N/A SER 123.A OG VAL 119.A O no hydrogen 3.119 N/A SER 123.A OG ASP 120.A O no hydrogen 3.234 N/A ALA 124.A N ASP 120.A O no hydrogen 2.974 N/A ASN 125.A N LEU 122.A O no hydrogen 3.193 N/A ASN 125.A ND2 ILE 121.A O no hydrogen 3.077 N/A GLY 126.A N SER 123.A O no hydrogen 2.989 N/A TYR 127.A N LEU 122.A O no hydrogen 3.029 N/A LEU 128.A N LYS 266.A O no hydrogen 3.244 N/A ASN 129.A ND2 SER 28.A O no hydrogen 3.038 N/A ASN 129.A ND2 SER 31.A O no hydrogen 3.199 N/A ALA 130.A N TYR 127.A O no hydrogen 3.174 N/A THR 131.A N LEU 128.A O no hydrogen 3.073 N/A THR 131.A OG1 LEU 128.A O no hydrogen 2.950 N/A THR 132.A N ASN 129.A O no hydrogen 2.974 N/A MET 134.A N ALA 130.A O no hydrogen 3.167 N/A ASP 135.A N.A THR 131.A O no hydrogen 3.159 N/A ASP 135.A N.B THR 131.A O no hydrogen 3.223 N/A LEU 136.A N THR 132.A O no hydrogen 3.246 N/A ALA 137.A N ALA 133.A O no hydrogen 2.860 N/A GLN 138.A N MET 134.A O no hydrogen 3.086 N/A GLN 138.A NE2 CYS 303.A O no hydrogen 2.895 N/A GLN 138.A NE2 ASP 310.A OD2 no hydrogen 3.041 N/A MET 139.A N ASP 135.A O.A no hydrogen 3.236 N/A MET 139.A N ASP 135.A O.B no hydrogen 3.269 N/A LEU 140.A N LEU 136.A O no hydrogen 3.033 N/A ILE 141.A N ALA 137.A O no hydrogen 3.352 N/A ILE 141.A N GLN 138.A O no hydrogen 3.218 N/A GLN 142.A N GLN 138.A O no hydrogen 3.145 N/A GLN 142.A NE2 THR 244.A O no hydrogen 3.204 N/A GLN 142.A NE2 SER 305.A O no hydrogen 2.840 N/A GLY 143.A N MET 139.A O no hydrogen 2.868 N/A TRP 145.A NE1 SER 92.A OG no hydrogen 2.835 N/A ASP 148.A N TRP 145.A O no hydrogen 2.997 N/A LEU 151.A N ASN 149.A OD1 no hydrogen 3.084 N/A ARG 152.A N ASN 149.A O no hydrogen 3.034 N/A ARG 152.A NH1 PHE 157.A O no hydrogen 3.518 N/A ARG 152.A NH1 ASN 159.A OD1 no hydrogen 2.761 N/A ARG 152.A NH2 ASN 159.A OD1 no hydrogen 2.753 N/A GLN 153.A N PRO 150.A O no hydrogen 3.186 N/A GLN 153.A NE2 PRO 150.A O no hydrogen 2.995 N/A GLN 153.A NE2 LEU 307.A O no hydrogen 3.081 N/A ILE 154.A N LEU 151.A O no hydrogen 3.031 N/A HIS 156.A NE2 GLN 197.A OE1 no hydrogen 2.636 N/A PHE 157.A N ILE 154.A O no hydrogen 3.292 N/A ILE 161.A N ASN 158.A OD1 no hydrogen 2.961 N/A LEU 162.A N ASN 158.A O no hydrogen 2.952 N/A GLU 163.A N ASN 159.A O no hydrogen 3.118 N/A LYS 164.A N LYS 160.A O no hydrogen 3.169 N/A CYS 165.A N ILE 161.A O no hydrogen 3.016 N/A CYS 165.A SG ILE 161.A O no hydrogen 3.477 N/A LYS 166.A N LEU 162.A O no hydrogen 3.044 N/A GLU 167.A N GLU 163.A O no hydrogen 3.053 N/A ILE 168.A N CYS 165.A O no hydrogen 3.174 N/A ASN 169.A N LYS 166.A O no hydrogen 2.982 N/A VAL 170.A N CYS 165.A O no hydrogen 2.858 N/A GLU 171.A N ASP 175.A OD2 no hydrogen 2.995 N/A THR 172.A N ASP 175.A OD2 no hydrogen 3.142 N/A TYR 174.A OH.A PRO 206.A O no hydrogen 2.982 N/A ASP 175.A N THR 172.A OG1 no hydrogen 3.088 N/A ILE 176.A N THR 172.A O no hydrogen 3.295 N/A MET 177.A N VAL 173.A O no hydrogen 3.145 N/A ALA 178.A N TYR 174.A O.A no hydrogen 3.158 N/A ALA 178.A N TYR 174.A O.B no hydrogen 2.903 N/A LEU 179.A N ILE 176.A O no hydrogen 3.264 N/A ARG 184.A N GLU 180.A O.A no hydrogen 2.776 N/A ARG 184.A N GLU 180.A O.B no hydrogen 2.796 N/A ARG 184.A NH1 LEU 179.A O no hydrogen 3.229 N/A ASP 185.A N ASP 181.A O no hydrogen 2.915 N/A GLU 186.A N GLU 182.A O no hydrogen 3.122 N/A ILE 187.A N GLU 183.A O no hydrogen 3.349 N/A LEU 188.A N ARG 184.A O no hydrogen 3.004 N/A THR 189.A N ILE 187.A O no hydrogen 2.954 N/A THR 191.A N GLN 194.A OE1 no hydrogen 2.920 N/A LEU 195.A N THR 191.A O no hydrogen 2.851 N/A ALA 196.A N ASP 192.A O no hydrogen 3.104 N/A GLN 197.A N SER 193.A O no hydrogen 3.368 N/A VAL 198.A N GLN 194.A O no hydrogen 3.058 N/A ALA 199.A N LEU 195.A O no hydrogen 2.962 N/A ALA 200.A N ALA 196.A O no hydrogen 2.851 N/A PHE 201.A N GLN 197.A O no hydrogen 3.207 N/A VAL 202.A N VAL 198.A O no hydrogen 2.970 N/A ASN 203.A N ALA 199.A O no hydrogen 3.137 N/A ASN 204.A N PHE 201.A O no hydrogen 3.207 N/A TYR 205.A N PHE 201.A O no hydrogen 2.954 N/A TYR 205.A OH LEU 307.A O no hydrogen 2.731 N/A GLU 209.A N.A THR 233.A O no hydrogen 3.005 N/A GLU 209.A N.B THR 233.A O no hydrogen 2.992 N/A THR 211.A N GLN 231.A O no hydrogen 2.992 N/A THR 211.A OG1 GLN 231.A O no hydrogen 3.516 N/A SER 213.A N THR 229.A O no hydrogen 2.920 N/A SER 217.A OG ASP 218.A OD1 no hydrogen 3.316 N/A SER 222.A OG PRO 290.A O no hydrogen 3.031 N/A GLY 223.A N THR 289.A O no hydrogen 2.848 N/A VAL 224.A N ILE 221.A O no hydrogen 3.439 N/A GLN 226.A N PHE 287.A O no hydrogen 2.706 N/A GLN 226.A NE2 LYS 227.A O no hydrogen 3.449 N/A ILE 228.A N LEU 285.A O.A no hydrogen 2.879 N/A ILE 228.A N LEU 285.A O.B no hydrogen 2.787 N/A THR 229.A N SER 213.A O no hydrogen 3.129 N/A ILE 230.A N TYR 283.A O no hydrogen 2.755 N/A GLN 231.A N THR 211.A O no hydrogen 2.913 N/A LEU 232.A N.A GLN 281.A O no hydrogen 2.779 N/A LEU 232.A N.B GLN 281.A O no hydrogen 2.772 N/A THR 233.A N GLU 209.A O.A no hydrogen 3.124 N/A THR 233.A N GLU 209.A O.B no hydrogen 3.119 N/A ARG 234.A N GLU 279.A O no hydrogen 2.724 N/A ARG 234.A NH1 GLU 254.A OE2 no hydrogen 2.965 N/A ARG 234.A NH1 LEU 276.A O no hydrogen 2.858 N/A GLN 242.A N ASN 240.A OD1 no hydrogen 3.134 N/A GLN 242.A NE2 LYS 252.A O no hydrogen 3.651 N/A VAL 243.A N LYS 252.A O no hydrogen 2.895 N/A THR 244.A N TYR 306.A OH no hydrogen 3.258 N/A SER 245.A OG ILE 141.A O no hydrogen 2.647 N/A TYR 248.A N SER 245.A OG no hydrogen 3.187 N/A LYS 252.A NZ LEU 253.A O no hydrogen 2.870 N/A LYS 252.A NZ ASP 304.A OD1 no hydrogen 3.498 N/A LYS 252.A NZ ASP 304.A OD2 no hydrogen 2.686 N/A GLU 254.A N LEU 241.A O no hydrogen 2.823 N/A SER 255.A N ASP 304.A OD1 no hydrogen 3.035 N/A SER 255.A OG VAL 274.A O no hydrogen 3.408 N/A TRP 256.A N VAL 274.A O no hydrogen 3.007 N/A TRP 256.A NE1 GLU 254.A OE2 no hydrogen 3.024 N/A TRP 257.A N VAL 302.A O no hydrogen 2.716 N/A LEU 258.A N LYS 272.A O no hydrogen 2.804 N/A VAL 259.A N TRP 300.A O no hydrogen 2.946 N/A LEU 260.A N ALA 270.A O no hydrogen 2.972 N/A GLY 261.A N THR 298.A O no hydrogen 3.097 N/A GLU 262.A N GLU 267.A O no hydrogen 2.986 N/A LYS 265.A N GLU 262.A O no hydrogen 3.198 N/A LYS 266.A N VAL 263.A O no hydrogen 3.145 N/A GLU 267.A N GLU 262.A O no hydrogen 3.366 N/A LEU 268.A N GLY 126.A O no hydrogen 2.895 N/A TYR 269.A N LEU 260.A O no hydrogen 2.739 N/A TYR 269.A OH GLU 262.A OE1 no hydrogen 2.605 N/A ALA 270.A N LEU 260.A O no hydrogen 3.349 N/A LYS 272.A N LEU 258.A O no hydrogen 2.946 N/A LYS 273.A NZ SER 255.A OG no hydrogen 3.310 N/A VAL 274.A N TRP 256.A O no hydrogen 2.934 N/A ASN 277.A ND2 THR 275.A O no hydrogen 3.176 N/A ASN 277.A ND2 THR 275.A OG1 no hydrogen 2.772 N/A LYS 278.A N GLN 281.A OE1 no hydrogen 3.060 N/A GLN 281.A N LEU 232.A O.A no hydrogen 3.156 N/A GLN 281.A N LEU 232.A O.B no hydrogen 3.024 N/A GLN 281.A NE2 LEU 232.A O.A no hydrogen 2.819 N/A GLN 281.A NE2 LEU 232.A O.B no hydrogen 3.012 N/A GLN 281.A NE2 LYS 278.A O no hydrogen 3.131 N/A GLN 282.A NE2 GLN 231.A OE1 no hydrogen 3.040 N/A TYR 283.A N ILE 230.A O no hydrogen 2.727 N/A LEU 285.A N.A ILE 228.A O no hydrogen 2.817 N/A LEU 285.A N.B ILE 228.A O no hydrogen 2.817 N/A PHE 287.A N GLN 226.A O no hydrogen 2.944 N/A THR 289.A N VAL 224.A O no hydrogen 2.979 N/A THR 289.A OG1 VAL 224.A O no hydrogen 2.625 N/A SER 292.A OG LYS 320.A O no hydrogen 3.150 N/A GLY 293.A N VAL 319.A O no hydrogen 3.047 N/A LYS 294.A NZ ASN 296.A OD1.A no hydrogen 3.533 N/A HIS 295.A N ILE 317.A O no hydrogen 3.026 N/A HIS 295.A ND1 GLU 262.A OE2 no hydrogen 3.094 N/A HIS 295.A NE2 THR 291.A O no hydrogen 2.737 N/A LEU 297.A N PHE 315.A O no hydrogen 2.872 N/A THR 298.A N GLY 261.A O no hydrogen 2.899 N/A THR 298.A OG1 SER 314.A OG no hydrogen 3.011 N/A ILE 299.A N LEU 313.A O no hydrogen 2.777 N/A TRP 300.A N VAL 259.A O no hydrogen 2.859 N/A CYS 301.A N LYS 311.A O no hydrogen 2.754 N/A VAL 302.A N TRP 257.A O no hydrogen 2.882 N/A CYS 303.A N ASP 310.A OD1 no hydrogen 2.922 N/A CYS 303.A SG SER 255.A O no hydrogen 3.681 N/A ASP 304.A N SER 255.A O no hydrogen 2.857 N/A SER 305.A OG ASP 304.A OD1 no hydrogen 2.750 N/A LEU 307.A N GLN 153.A OE1 no hydrogen 2.727 N/A LYS 311.A N CYS 301.A O no hydrogen 3.118 N/A LEU 313.A N ILE 299.A O no hydrogen 2.859 N/A SER 314.A OG THR 298.A OG1 no hydrogen 3.011 N/A PHE 315.A N LEU 297.A O no hydrogen 2.903 N/A ILE 317.A N HIS 295.A O no hydrogen 3.029 N/A ASN 318.A ND2 GLU 316.A OE1 no hydrogen 3.050 N/A VAL 319.A N GLY 293.A O no hydrogen 3.044 N/A LYS 320.A N LEU 220.A O no hydrogen 3.100 N/A LYS 320.A NZ ASP 218.A O no hydrogen 2.790 N/A