Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 3liz_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LEU 5.A N ASN 146.A O no hydrogen 2.992 N/A TYR 6.A N LEU 147.A O no hydrogen 2.867 N/A VAL 9.A N PHE 170.A O no hydrogen 2.918 N/A HIS 10.A NE2 ASP 174.A OD1 no hydrogen 2.499 N/A VAL 11.A N ILE 168.A O no hydrogen 2.854 N/A ILE 13.A N GLY 166.A O no hydrogen 2.996 N/A ASN 14.A N ALA 18.A O no hydrogen 2.832 N/A THR 15.A OG1 HIS 164.A O no hydrogen 2.678 N/A GLN 16.A N ASN 14.A OD1 no hydrogen 2.804 N/A TYR 17.A N ASN 14.A O no hydrogen 3.005 N/A TYR 17.A OH ASP 304.A OD1 no hydrogen 2.803 N/A ALA 18.A N ASN 14.A OD1 no hydrogen 2.925 N/A GLY 19.A N THR 30.A O no hydrogen 2.902 N/A THR 21.A N PHE 28.A O no hydrogen 3.024 N/A THR 21.A OG1 THR 30.A OG1 no hydrogen 2.707 N/A LYS 22.A N THR 92.A O no hydrogen 2.856 N/A ILE 23.A N GLN 26.A O no hydrogen 2.937 N/A GLY 24.A N SER 90.A O no hydrogen 3.073 N/A GLN 26.A N ILE 23.A O no hydrogen 3.117 N/A GLN 26.A NE2 LYS 58.A O no hydrogen 2.628 N/A PHE 28.A N THR 21.A O no hydrogen 2.748 N/A LEU 29.A N ASP 119.A OD1 no hydrogen 2.857 N/A THR 30.A N GLY 19.A O no hydrogen 2.760 N/A THR 30.A OG1 THR 21.A OG1 no hydrogen 2.707 N/A THR 30.A OG1 PHE 28.A O no hydrogen 2.961 N/A VAL 31.A N VAL 120.A O no hydrogen 2.891 N/A PHE 32.A N TYR 17.A O no hydrogen 3.121 N/A ASP 33.A N VAL 122.A O no hydrogen 3.051 N/A SER 34.A N THR 218.A OG1 no hydrogen 2.995 N/A SER 34.A OG ILE 216.A O no hydrogen 2.651 N/A THR 35.A N ASP 33.A OD1 no hydrogen 2.997 N/A THR 35.A OG1 ASP 33.A OD1 no hydrogen 2.688 N/A THR 35.A OG1 ASP 33.A OD2 no hydrogen 3.447 N/A SER 36.A N ASP 33.A O no hydrogen 3.271 N/A SER 36.A OG ASP 33.A OD2 no hydrogen 2.633 N/A VAL 40.A N VAL 121.A O no hydrogen 2.872 N/A VAL 41.A N VAL 104.A O no hydrogen 3.088 N/A SER 43.A N ALA 106.A O no hydrogen 2.865 N/A SER 43.A OG GLU 45.A OE2 no hydrogen 3.554 N/A SER 43.A OG ALA 106.A O no hydrogen 3.260 N/A SER 43.A OG ASP 107.A OD1 no hydrogen 2.706 N/A GLN 44.A NE2 TYR 59.A O no hydrogen 2.875 N/A GLU 45.A N SER 43.A OG no hydrogen 3.301 N/A CYS 46.A N SER 43.A O no hydrogen 3.076 N/A CYS 46.A SG ASP 107.A O no hydrogen 3.677 N/A ALA 50.A N LEU 109.A O no hydrogen 2.887 N/A CYS 51.A N GLY 48.A O no hydrogen 3.004 N/A VAL 52.A N GLY 49.A O no hydrogen 3.199 N/A LEU 56.A N CYS 53A.A O no hydrogen 3.265 N/A GLN 57.A N ASP 119.A OD2 no hydrogen 2.867 N/A GLN 57.A NE2 ASN 55.A O no hydrogen 3.111 N/A LYS 58.A NZ CYS 46.A O no hydrogen 2.703 N/A TYR 59.A N ALA 42.A O no hydrogen 2.783 N/A TYR 59.A OH ASP 89.A OD2 no hydrogen 2.498 N/A GLU 60.A N GLN 26.A OE1 no hydrogen 2.948 N/A ILE 67.A N GLY 86.A O no hydrogen 2.889 N/A SER 68.A OG GLY 70.A O no hydrogen 2.752 N/A VAL 72.A N GLY 84.A O no hydrogen 2.768 N/A VAL 74.A N ALA 82.A O no hydrogen 2.863 N/A PHE 76.A N GLY 80.A O no hydrogen 2.975 N/A THR 79.A N ASP 78.A OD1 no hydrogen 2.868 N/A THR 79.A OG1 ASP 78.A OD1 no hydrogen 3.377 N/A THR 79.A OG1 GLU 112.A OE2 no hydrogen 2.686 N/A SER 81.A N SER 110.A OG no hydrogen 2.909 N/A ALA 82.A N VAL 74.A O no hydrogen 3.126 N/A VAL 83.A N GLU 108.A O no hydrogen 3.027 N/A GLY 84.A N VAL 72.A O no hydrogen 3.082 N/A ARG 85.A NE SER 68.A O no hydrogen 3.014 N/A ARG 85.A NH2 SER 68.A O no hydrogen 3.069 N/A GLY 86.A N SER 68.A OG no hydrogen 2.922 N/A ILE 87.A N ILE 103.A O no hydrogen 2.779 N/A GLU 88.A N LYS 65.A O no hydrogen 2.860 N/A ASP 89.A N GLN 101.A O no hydrogen 3.171 N/A SER 90.A N ASP 89.A OD1 no hydrogen 2.815 N/A LEU 91.A N THR 98.A O no hydrogen 2.813 N/A THR 92.A N LYS 22.A O no hydrogen 2.871 N/A THR 92.A OG1 THR 97.A OG1 no hydrogen 2.897 N/A ILE 93.A N LEU 96.A O no hydrogen 2.801 N/A GLN 95.A N GLN 95.A OE1 no hydrogen 2.787 N/A LEU 96.A N ILE 93.A O no hydrogen 3.031 N/A THR 97.A OG1 LEU 91.A O no hydrogen 3.520 N/A THR 97.A OG1 THR 92.A OG1 no hydrogen 2.897 N/A THR 98.A N LEU 91.A O no hydrogen 3.039 N/A THR 98.A OG1 GLU 145.A OE1 no hydrogen 2.807 N/A GLN 101.A N ASP 89.A O no hydrogen 2.711 N/A GLN 101.A NE2 ASP 102.A O no hydrogen 3.242 N/A GLN 101.A NE2 LYS 136.A O no hydrogen 3.057 N/A ILE 103.A N ILE 87.A O no hydrogen 2.862 N/A VAL 104.A N VAL 39.A O no hydrogen 2.754 N/A LEU 105.A N ARG 85.A O no hydrogen 2.879 N/A ALA 106.A N VAL 41.A O no hydrogen 2.716 N/A ASP 107.A N VAL 83.A O no hydrogen 2.831 N/A GLU 108.A N VAL 83.A O no hydrogen 3.200 N/A SER 110.A N SER 81.A O no hydrogen 2.952 N/A SER 110.A OG SER 81.A O no hydrogen 3.151 N/A SER 110.A OG GLU 112.A OE1 no hydrogen 2.619 N/A GLU 112.A N GLU 112.A OE1 no hydrogen 2.784 N/A ILE 115.A N GLN 111.A O no hydrogen 3.010 N/A LEU 116.A N GLU 112.A O no hydrogen 3.215 N/A SER 117.A N CYS 114.A O no hydrogen 2.839 N/A ALA 118.A N VAL 113.A O no hydrogen 3.119 N/A ASP 119.A N LEU 29.A O no hydrogen 2.770 N/A VAL 120.A N LEU 29.A O no hydrogen 3.096 N/A VAL 121.A N VAL 40.A O no hydrogen 3.195 N/A VAL 122.A N VAL 31.A O no hydrogen 2.875 N/A GLY 123.A N ASN 38.A O no hydrogen 2.863 N/A ILE 124.A N ASP 33.A O no hydrogen 2.887 N/A ALA 125.A N SER 36.A O no hydrogen 2.917 N/A CYS 129.A N ALA 126.A O no hydrogen 2.853 N/A CYS 129.A SG ALA 126.A O no hydrogen 3.051 N/A ALA 132.A N ASN 38.A OD1 no hydrogen 3.012 N/A LEU 133.A N ASN 131.A OD1 no hydrogen 3.233 N/A LYS 134.A N ASN 131.A O no hydrogen 2.959 N/A GLY 135.A N ASN 131.A OD1 no hydrogen 3.124 N/A LYS 136.A NZ GLU 144.A OE1 no hydrogen 2.875 N/A LYS 136.A NZ GLU 144.A OE2 no hydrogen 3.063 N/A GLU 140.A N THR 137.A OG1 no hydrogen 3.414 N/A ASN 141.A N THR 137.A O no hydrogen 3.000 N/A ASN 141.A ND2 GLN 101.A OE1 no hydrogen 2.783 N/A PHE 142.A N VAL 138.A O no hydrogen 2.904 N/A VAL 143.A N LEU 139.A O no hydrogen 3.068 N/A GLU 144.A N GLU 140.A O no hydrogen 2.967 N/A GLU 145.A N ASN 141.A O no hydrogen 2.925 N/A ASN 146.A N VAL 143.A O no hydrogen 2.871 N/A LEU 147.A N PHE 142.A O no hydrogen 3.038 N/A VAL 151.A N ALA 149.A O no hydrogen 2.939 N/A PHE 152.A N PHE 314.A O no hydrogen 3.113 N/A SER 153.A N ILE 169.A O no hydrogen 2.839 N/A SER 153.A OG GLY 172.A O no hydrogen 2.789 N/A SER 153.A OG TYR 311.A OH no hydrogen 2.601 N/A ILE 154.A N SER 312.A O no hydrogen 2.909 N/A HIS 155.A N GLU 167.A O no hydrogen 3.173 N/A HIS 155.A NE2 GLU 167.A OE2 no hydrogen 2.770 N/A HIS 156.A NE2 ASN 14.A O no hydrogen 2.812 N/A ALA 157.A N PHE 165.A O no hydrogen 2.894 N/A ARG 158.A NE ASP 308.A OD2 no hydrogen 2.725 N/A ARG 158.A NH2 ASP 308.A OD2 no hydrogen 3.369 N/A PHE 159.A N GLU 163.A O no hydrogen 2.680 N/A GLU 163.A N ASP 161A.A OD1 no hydrogen 3.189 N/A PHE 165.A N ALA 157.A O no hydrogen 3.072 N/A GLY 166.A N ILE 13.A O no hydrogen 2.970 N/A GLU 167.A N HIS 155.A O no hydrogen 3.069 N/A ILE 168.A N VAL 11.A O no hydrogen 2.911 N/A ILE 169.A N SER 153.A O no hydrogen 2.795 N/A PHE 170.A N VAL 9.A O no hydrogen 2.819 N/A GLY 171.A N VAL 151.A O no hydrogen 2.834 N/A SER 173.A OG GLU 313.A OE2 no hydrogen 2.634 N/A ASP 174.A N TYR 311.A OH no hydrogen 2.884 N/A LYS 176.A NZ ASP 174.A OD1 no hydrogen 2.835 N/A TYR 177.A N ASP 174.A O no hydrogen 3.083 N/A TYR 177.A OH GLU 167.A OE2 no hydrogen 2.827 N/A VAL 178.A N TRP 175.A O no hydrogen 3.117 N/A ASP 179.A N ARG 325.A O no hydrogen 2.767 N/A THR 183.A N PHE 323.A O no hydrogen 2.797 N/A VAL 185.A N MET 321.A O no hydrogen 2.909 N/A LEU 187.A N LYS 319.A O no hydrogen 2.993 N/A VAL 188.A N LYS 194.A O no hydrogen 3.012 N/A TRP 193.A NE1 ILE 124.A O no hydrogen 2.797 N/A LYS 194.A N SER 192.A OG no hydrogen 3.124 N/A PHE 195.A N ALA 214.A O no hydrogen 2.934 N/A LEU 197.A N THR 212.A O no hydrogen 2.767 N/A ASP 198.A N VAL 266.A O no hydrogen 2.881 N/A VAL 200.A N ALA 208.A O no hydrogen 3.171 N/A LYS 201.A N THR 264.A O no hydrogen 2.957 N/A LYS 201.A NZ ASN 271.A OD1 no hydrogen 3.509 N/A ILE 202.A N THR 205.A O no hydrogen 2.925 N/A GLY 203.A N ASP 262.A O no hydrogen 2.950 N/A THR 205.A N ILE 202.A O no hydrogen 2.984 N/A VAL 207.A N VAL 200.A O no hydrogen 2.731 N/A ALA 208.A N VAL 200.A O no hydrogen 3.233 N/A GLY 211.A N LEU 197.A O no hydrogen 2.790 N/A THR 212.A N PRO 209.A O no hydrogen 3.213 N/A THR 212.A OG1 PRO 209.A O no hydrogen 2.685 N/A ALA 214.A N PHE 195.A O no hydrogen 2.804 N/A ILE 215.A N PHE 300.A O no hydrogen 2.983 N/A ASP 217.A N ILE 302.A O no hydrogen 2.863 N/A THR 218.A N SER 34.A OG no hydrogen 3.000 N/A THR 218.A OG1 PHE 32.A O no hydrogen 2.558 N/A SER 219.A N ASP 217.A OD1 no hydrogen 2.894 N/A SER 219.A OG ASP 217.A OD1 no hydrogen 2.611 N/A LYS 220.A N ASP 217.A O no hydrogen 3.231 N/A LYS 220.A NZ ASP 217.A OD2 no hydrogen 2.837 N/A ILE 223.A N GLY 290.A O no hydrogen 2.959 N/A VAL 224.A N PHE 301.A O no hydrogen 3.054 N/A GLY 225.A N GLN 292.A O no hydrogen 2.967 N/A LYS 227.A N CYS 294.A O no hydrogen 2.922 N/A TYR 229.A N PRO 226.A O no hydrogen 2.928 N/A VAL 230.A N PRO 226.A O no hydrogen 2.911 N/A ASN 231.A N LYS 227.A O no hydrogen 2.953 N/A ASN 234.A N VAL 230.A O no hydrogen 3.108 N/A ASN 234.A ND2 PHE 291.A O no hydrogen 2.992 N/A GLU 235.A N ASN 231.A O no hydrogen 2.857 N/A ALA 236.A N PRO 232.A O no hydrogen 3.021 N/A ILE 237.A N ILE 233.A O no hydrogen 3.202 N/A GLY 238.A N GLU 235.A O no hydrogen 3.141 N/A CYS 239.A N ASN 234.A O no hydrogen 3.210 N/A CYS 239.A SG.A ASN 234.A O no hydrogen 3.300 N/A CYS 239.A SG.B CYS 250.A O no hydrogen 3.705 N/A VAL 240.A N LYS 251.A O no hydrogen 2.870 N/A GLU 242.A N ILE 249.A O no hydrogen 2.957 N/A THR 244.A N ARG 247C.A O no hydrogen 2.811 N/A THR 244.A OG1 THR 246B.A OG1 no hydrogen 3.136 N/A THR 244.A OG1 ARG 247C.A O no hydrogen 3.230 N/A ILE 249.A N GLU 242.A O no hydrogen 3.182 N/A LYS 251.A N VAL 240.A O no hydrogen 3.004 N/A LEU 252.A N CYS 287.A O no hydrogen 2.930 N/A CYS 254.A SG ASN 285.A O no hydrogen 3.353 N/A SER 255.A N ASP 253.A OD2.A no hydrogen 3.143 N/A SER 255.A OG ASP 253.A OD2.A no hydrogen 2.901 N/A LYS 256.A N ASP 253.A O.A no hydrogen 2.957 N/A LYS 256.A N ASP 253.A O.B no hydrogen 3.014 N/A LYS 256.A NZ ASP 253.A OD1.A no hydrogen 3.365 N/A ILE 257.A N CYS 254.A O no hydrogen 3.271 N/A SER 259.A N LYS 256.A O no hydrogen 3.119 N/A SER 259.A OG LYS 256.A O no hydrogen 2.641 N/A LEU 260.A N ILE 257.A O no hydrogen 3.235 N/A VAL 263.A N ILE 274.A O no hydrogen 3.049 N/A THR 264.A N LYS 201.A O no hydrogen 2.811 N/A PHE 265.A N PHE 272.A O no hydrogen 2.991 N/A VAL 266.A N GLY 199.A O no hydrogen 2.908 N/A ILE 267.A N ARG 270.A O no hydrogen 2.905 N/A ASN 268.A ND2 TYR 184.A O no hydrogen 2.693 N/A GLY 269.A N ASP 198.A OD1 no hydrogen 2.798 N/A ARG 270.A N ILE 267.A O no hydrogen 2.932 N/A ARG 270.A NH1 GLU 181.A O no hydrogen 3.016 N/A ARG 270.A NH1 THR 183.A OG1 no hydrogen 2.948 N/A PHE 272.A N PHE 265.A O no hydrogen 2.833 N/A ILE 274.A N VAL 263.A O no hydrogen 2.683 N/A SER 276.A OG ILE 257.A O no hydrogen 2.581 N/A TYR 278.A N SER 275.A O no hydrogen 2.921 N/A TYR 279.A N SER 275.A O no hydrogen 3.051 N/A TYR 279.A OH PRO 261.A O no hydrogen 2.680 N/A ILE 280.A N SER 276.A O no hydrogen 2.960 N/A GLN 281.A N TYR 288.A O no hydrogen 2.704 N/A GLN 281.A NE2 TYR 278.A O no hydrogen 3.451 N/A GLN 281.A NE2 TYR 279.A O no hydrogen 3.253 N/A GLN 282.A NE2 GLY 284.A O no hydrogen 2.842 N/A ASN 283.A N LEU 286.A O no hydrogen 2.804 N/A LEU 286.A N ASN 283.A O no hydrogen 2.984 N/A TYR 288.A N GLN 281.A O no hydrogen 2.964 N/A TYR 288.A OH ASN 283.A OD1 no hydrogen 2.585 N/A SER 289.A N CYS 250.A O no hydrogen 2.901 N/A SER 289.A OG ASN 234.A OD1 no hydrogen 2.550 N/A SER 289.A OG PHE 291.A O no hydrogen 3.463 N/A PHE 291.A N SER 289.A OG no hydrogen 3.021 N/A GLN 292.A N ILE 223.A O no hydrogen 2.780 N/A CYS 294.A N GLY 225.A O no hydrogen 2.770 N/A ASP 298.A N ASP 298.A OD1 no hydrogen 2.435 N/A PHE 300.A N GLN 213.A O no hydrogen 2.903 N/A PHE 301.A N VAL 224.A O no hydrogen 2.820 N/A ILE 302.A N ILE 215.A O no hydrogen 2.842 N/A ASP 304.A N LYS 220.A O no hydrogen 2.910 N/A PHE 306.A N GLY 303.A O no hydrogen 3.210 N/A VAL 307.A N GLY 303.A O no hydrogen 3.431 N/A ASP 308.A N ASP 304.A O no hydrogen 2.759 N/A HIS 309.A N PHE 306.A O no hydrogen 2.936 N/A TYR 310.A N PHE 306.A O no hydrogen 2.938 N/A TYR 310.A OH ASN 273.A O no hydrogen 2.708 N/A TYR 311.A OH SER 153.A OG no hydrogen 2.601 N/A SER 312.A N ILE 154.A O no hydrogen 3.224 N/A SER 312.A OG TYR 310.A O no hydrogen 2.943 N/A GLU 313.A N GLY 322.A O no hydrogen 2.773 N/A PHE 314.A N PHE 152.A O no hydrogen 2.790 N/A ASN 315.A N THR 320.A O no hydrogen 2.916 N/A ASN 315.A ND2 GLU 313.A OE1 no hydrogen 3.099 N/A TRP 316.A N PRO 150.A O no hydrogen 2.903 N/A GLU 317.A N PRO 150.A O no hydrogen 3.140 N/A ASN 318.A N ASN 315.A OD1 no hydrogen 2.932 N/A LYS 319.A N TRP 316.A O no hydrogen 3.105 N/A LYS 319.A NZ.A ASP 190.A OD1 no hydrogen 2.752 N/A LYS 319.A NZ.B TRP 316.A O no hydrogen 2.792 N/A THR 320.A N ASN 315.A O no hydrogen 2.994 N/A MET 321.A N VAL 185.A O no hydrogen 2.968 N/A GLY 322.A N GLU 313.A O no hydrogen 2.877 N/A PHE 323.A N THR 183.A O no hydrogen 2.742 N/A GLY 324.A N TYR 311.A O no hydrogen 3.013 N/A ARG 325.A NE GLU 328.A OE2 no hydrogen 2.934 N/A ARG 325.A NH2 GLU 328.A OE2 no hydrogen 2.929 N/A SER 326.A N HIS 309.A O no hydrogen 2.888 N/A VAL 327.A N TYR 177.A O no hydrogen 2.813 N/A SER 329.A OG ARG 158.A O no hydrogen 2.804 N/A CYS 53A.A N ALA 50.A O no hydrogen 3.137 N/A PHE 77A.A N ASP 33.A OD2 no hydrogen 2.842 N/A GLY 162B.A N PHE 159.A O no hydrogen 2.735 N/A THR 246B.A OG1 THR 244.A OG1 no hydrogen 3.136 N/A ARG 247C.A N THR 244.A OG1 no hydrogen 3.134 N/A