Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 3tjx_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): SER 4.A N GLN 293.A O no hydrogen 2.866 N/A GLN 6.A N SER 4.A OG no hydrogen 3.086 N/A VAL 7.A N PHE 14.A O no hydrogen 2.898 N/A LEU 9.A N ASN 12.A O no hydrogen 3.068 N/A ASN 12.A N LEU 9.A O no hydrogen 2.856 N/A THR 13.A OG1 ASN 8.A OD1 no hydrogen 2.918 N/A PHE 14.A N VAL 7.A O no hydrogen 2.734 N/A ASN 16.A ND2 ALA 39.A O no hydrogen 2.795 N/A PHE 18.A N ASN 16.A OD1 no hydrogen 2.901 N/A MET 19.A N VAL 262.A O no hydrogen 3.083 N/A ASN 20.A ND2 ALA 21.A O no hydrogen 3.147 N/A ASN 20.A ND2 VAL 24.A O no hydrogen 3.256 N/A ASN 20.A ND2 VAL 44.A O no hydrogen 2.913 N/A ALA 21.A N VAL 264.A O no hydrogen 2.967 N/A VAL 24.A N ALA 21.A O no hydrogen 3.024 N/A CYS 26.A SG VAL 24.A O no hydrogen 3.445 N/A CYS 26.A SG VAL 44.A O no hydrogen 3.104 N/A THR 27.A N GLU 31.A OE1 no hydrogen 2.797 N/A THR 28.A N GLU 31.A OE1 no hydrogen 2.997 N/A GLU 31.A N THR 28.A OG1 no hydrogen 3.045 N/A LEU 32.A N THR 28.A O no hydrogen 2.883 N/A VAL 33.A N THR 29.A O no hydrogen 2.789 N/A ALA 34.A N GLU 30.A O no hydrogen 2.898 N/A MET 35.A N GLU 31.A O no hydrogen 2.887 N/A THR 36.A N LEU 32.A O no hydrogen 3.004 N/A THR 36.A OG1 LEU 32.A O no hydrogen 2.996 N/A THR 36.A OG1 TYR 85.A OH no hydrogen 2.994 N/A GLU 37.A N.A VAL 33.A O no hydrogen 2.864 N/A GLU 37.A N.B VAL 33.A O no hydrogen 2.857 N/A SER 38.A N MET 35.A O no hydrogen 3.226 N/A SER 38.A OG MET 35.A O no hydrogen 2.801 N/A SER 40.A N SER 38.A OG no hydrogen 3.033 N/A SER 40.A OG MET 35.A O no hydrogen 3.444 N/A SER 40.A OG SER 38.A OG no hydrogen 3.051 N/A SER 40.A OG SER 42.A O no hydrogen 2.799 N/A GLY 41.A N PHE 18.A O no hydrogen 2.770 N/A SER 42.A N PHE 18.A O no hydrogen 3.125 N/A SER 42.A OG LEU 43.A O no hydrogen 3.564 N/A SER 42.A OG PRO 96.A O no hydrogen 2.782 N/A LEU 43.A N SER 42.A OG no hydrogen 2.787 N/A VAL 44.A N ASN 20.A OD1 no hydrogen 2.885 N/A SER 45.A N PHE 98.A O no hydrogen 3.000 N/A LYS 46.A N CYS 26.A O no hydrogen 2.845 N/A SER 47.A OG SER 100.A OG no hydrogen 2.545 N/A CYS 48.A N SER 100.A O no hydrogen 3.102 N/A CYS 48.A SG SER 100.A O no hydrogen 3.539 N/A THR 49.A N ASN 76.A OD1 no hydrogen 3.132 N/A THR 49.A OG1 ALA 51.A O no hydrogen 2.728 N/A ARG 53.A N ASN 76.A O no hydrogen 2.993 N/A ARG 53.A NE GLY 73.A O no hydrogen 2.986 N/A ARG 53.A NH2 GLY 73.A O no hydrogen 2.950 N/A ASN 56.A N MET 72.A O no hydrogen 2.829 N/A ASN 56.A ND2 SER 71.A O no hydrogen 2.906 N/A ASN 56.A ND2 SER 71.A OG no hydrogen 3.096 N/A ARG 60.A NH1 GLU 54.A O no hydrogen 3.081 N/A ARG 60.A NH1 ASN 56.A O no hydrogen 2.855 N/A TYR 61.A OH GLU 270.A OE2 no hydrogen 2.944 N/A GLN 62.A N ILE 69.A O no hydrogen 2.952 N/A LEU 64.A N GLY 67.A O no hydrogen 2.822 N/A GLY 67.A N LEU 64.A O no hydrogen 3.050 N/A SER 68.A N GLY 215.A O no hydrogen 3.053 N/A SER 68.A OG THR 266.A OG1 no hydrogen 2.718 N/A ILE 69.A N GLN 62.A O no hydrogen 3.016 N/A ASN 70.A N GLY 213.A O no hydrogen 3.019 N/A SER 71.A N ARG 60.A O no hydrogen 2.809 N/A MET 72.A N ASN 70.A OD1 no hydrogen 3.024 N/A ASN 76.A N ARG 53.A O no hydrogen 3.161 N/A ASN 76.A ND2 THR 49.A OG1 no hydrogen 2.936 N/A ASN 76.A ND2 LEU 74.A O no hydrogen 2.909 N/A ASN 77.A N TYR 82.A OH no hydrogen 3.100 N/A GLY 78.A N ASN 76.A OD1 no hydrogen 2.844 N/A PHE 79.A N THR 49.A O no hydrogen 2.789 N/A PHE 81.A N GLY 78.A O no hydrogen 3.115 N/A TYR 82.A N GLY 78.A O no hydrogen 3.466 N/A TYR 82.A OH THR 27.A O no hydrogen 2.778 N/A LEU 83.A N PHE 79.A O no hydrogen 2.871 N/A ALA 84.A N ASP 80.A O no hydrogen 2.899 N/A TYR 85.A N PHE 81.A O no hydrogen 2.984 N/A TYR 85.A OH HIS 90.A ND1 no hydrogen 2.846 N/A ALA 86.A N TYR 82.A O no hydrogen 3.024 N/A ALA 87.A N LEU 83.A O no hydrogen 2.818 N/A GLU 88.A N.A ALA 84.A O no hydrogen 2.881 N/A GLU 88.A N.B ALA 84.A O no hydrogen 2.847 N/A GLN 89.A N TYR 85.A O no hydrogen 3.040 N/A HIS 90.A N TYR 85.A O no hydrogen 2.839 N/A HIS 90.A ND1 TYR 85.A OH no hydrogen 2.846 N/A HIS 90.A NE2 LYS 95.A O no hydrogen 2.762 N/A TYR 92.A OH ALA 86.A O no hydrogen 2.663 N/A GLY 93.A N ASP 91.A OD1 no hydrogen 3.025 N/A LYS 94.A N ASP 91.A O no hydrogen 3.004 N/A LYS 94.A NZ THR 36.A O no hydrogen 3.058 N/A LYS 94.A NZ SER 38.A O no hydrogen 3.411 N/A LYS 95.A NZ MET 35.A O no hydrogen 2.875 N/A LYS 95.A NZ THR 36.A O no hydrogen 3.030 N/A LYS 95.A NZ SER 38.A O no hydrogen 2.822 N/A LYS 95.A NZ SER 40.A O no hydrogen 2.851 N/A LYS 95.A NZ SER 40.A OG no hydrogen 2.918 N/A PHE 98.A N LEU 43.A O no hydrogen 2.964 N/A LEU 99.A N ILE 126.A O no hydrogen 2.830 N/A SER 100.A OG SER 47.A OG no hydrogen 2.545 N/A MET 101.A N GLU 128.A O no hydrogen 3.045 N/A SER 102.A N CYS 48.A O no hydrogen 2.895 N/A GLY 103.A N ASN 109.A OD1 no hydrogen 2.889 N/A LEU 104.A N GLU 108.A OE1 no hydrogen 2.773 N/A GLU 108.A N SER 105.A OG no hydrogen 3.225 N/A ASN 109.A N SER 105.A O no hydrogen 3.208 N/A VAL 110.A N MET 106.A O.A no hydrogen 2.886 N/A VAL 110.A N MET 106.A O.B no hydrogen 2.965 N/A GLU 111.A N ARG 107.A O no hydrogen 2.986 N/A MET 112.A N GLU 108.A O no hydrogen 3.042 N/A CYS 113.A N ASN 109.A O no hydrogen 2.884 N/A CYS 113.A SG ASN 109.A O no hydrogen 3.329 N/A LYS 114.A N VAL 110.A O no hydrogen 3.090 N/A LYS 114.A NZ GLU 111.A OE1.A no hydrogen 3.252 N/A ARG 115.A NH1 ASP 80.A OD1 no hydrogen 2.802 N/A ARG 115.A NH2 ASP 80.A OD1 no hydrogen 3.223 N/A LEU 116.A N MET 112.A O no hydrogen 2.860 N/A ALA 117.A N CYS 113.A O no hydrogen 3.048 N/A ALA 120.A N LEU 116.A O no hydrogen 2.932 N/A THR 121.A N ALA 117.A O no hydrogen 2.990 N/A THR 121.A OG1 ALA 117.A O no hydrogen 3.124 N/A THR 121.A OG1 HIS 153.A NE2 no hydrogen 2.850 N/A GLU 122.A N.A ALA 118.A O no hydrogen 2.955 N/A GLU 122.A N.B ALA 118.A O no hydrogen 2.957 N/A LYS 123.A N VAL 119.A O no hydrogen 2.758 N/A GLY 124.A N ALA 120.A O no hydrogen 2.894 N/A ILE 126.A N LEU 97.A O no hydrogen 2.970 N/A GLU 128.A N LEU 99.A O no hydrogen 2.935 N/A LEU 129.A N GLY 156.A O no hydrogen 2.791 N/A ASN 130.A N MET 101.A O no hydrogen 2.889 N/A ASN 130.A ND2 SER 47.A OG no hydrogen 3.318 N/A LEU 131.A N LYS 158.A O no hydrogen 3.144 N/A SER 132.A N ASN 130.A OD1 no hydrogen 2.819 N/A SER 132.A OG ASN 130.A OD1 no hydrogen 2.903 N/A SER 132.A OG LYS 158.A O no hydrogen 2.875 N/A ALA 134.A N LEU 131.A O no hydrogen 2.950 N/A TYR 135.A OH PRO 161.A O no hydrogen 2.574 N/A ASP 136.A N VAL 133.A O no hydrogen 3.094 N/A ALA 139.A N ASP 136.A OD1 no hydrogen 3.041 N/A MET 140.A N ASP 136.A O no hydrogen 2.937 N/A ARG 141.A N PHE 137.A O no hydrogen 2.990 N/A ARG 141.A NH1 GLU 177.A OE1.A no hydrogen 2.402 N/A ARG 141.A NH1 GLU 177.A OE1.B no hydrogen 3.004 N/A ARG 141.A NH2 GLU 177.A OE1.B no hydrogen 2.876 N/A ARG 141.A NH2 GLU 177.A OE2.A no hydrogen 2.779 N/A GLN 142.A N ASP 138.A O no hydrogen 2.949 N/A CYS 143.A N.A ALA 139.A O no hydrogen 2.974 N/A CYS 143.A N.B ALA 139.A O no hydrogen 2.984 N/A CYS 143.A SG.A ALA 139.A O no hydrogen 3.135 N/A LEU 144.A N MET 140.A O no hydrogen 3.061 N/A THR 145.A N ARG 141.A O no hydrogen 2.862 N/A THR 145.A OG1 ARG 141.A O no hydrogen 2.758 N/A ALA 146.A N GLN 142.A O no hydrogen 2.955 N/A VAL 147.A N CYS 143.A O.A no hydrogen 2.947 N/A VAL 147.A N CYS 143.A O.B no hydrogen 2.970 N/A SER 148.A N.A LEU 144.A O no hydrogen 2.821 N/A SER 148.A N.B LEU 144.A O no hydrogen 2.810 N/A SER 148.A OG.A LEU 144.A O no hydrogen 2.977 N/A GLU 149.A N THR 145.A O no hydrogen 2.880 N/A VAL 150.A N ALA 146.A O no hydrogen 3.243 N/A VAL 150.A N VAL 147.A O no hydrogen 3.246 N/A TYR 151.A N VAL 147.A O no hydrogen 2.842 N/A HIS 153.A NE2 ALA 117.A O no hydrogen 3.117 N/A PHE 155.A N LYS 180.A O no hydrogen 2.844 N/A GLY 156.A N LEU 127.A O no hydrogen 2.943 N/A VAL 157.A N.A PHE 183.A O no hydrogen 3.091 N/A VAL 157.A N.B PHE 183.A O no hydrogen 3.083 N/A LYS 158.A N LEU 129.A O no hydrogen 2.820 N/A MET 159.A N THR 185.A O no hydrogen 2.874 N/A TYR 162.A N ASN 226.A OD1 no hydrogen 2.895 N/A TYR 162.A OH ALA 134.A O no hydrogen 2.831 N/A ALA 167.A N ASP 164.A OD1 no hydrogen 2.731 N/A PHE 168.A N ASP 164.A O no hydrogen 3.055 N/A ASP 169.A N PHE 165.A O no hydrogen 2.824 N/A ALA 170.A N ALA 166.A O no hydrogen 2.942 N/A ALA 171.A N ALA 167.A O no hydrogen 2.932 N/A ALA 172.A N PHE 168.A O no hydrogen 2.950 N/A GLU 173.A N ASP 169.A O no hydrogen 2.934 N/A ILE 174.A N ALA 170.A O no hydrogen 3.209 N/A LEU 175.A N ALA 171.A O no hydrogen 2.914 N/A ASN 176.A N ALA 172.A O no hydrogen 2.829 N/A ASN 176.A ND2 ARG 233.A O no hydrogen 3.034 N/A GLU 177.A N.A ILE 174.A O no hydrogen 3.008 N/A GLU 177.A N.B ILE 174.A O no hydrogen 2.988 N/A PHE 178.A N LEU 175.A O no hydrogen 3.094 N/A LYS 180.A NZ SER 148.A O.A no hydrogen 2.803 N/A LYS 180.A NZ SER 148.A O.B no hydrogen 2.870 N/A LYS 180.A NZ TYR 151.A O no hydrogen 2.743 N/A VAL 181.A N PHE 178.A O no hydrogen 3.043 N/A GLN 182.A N.A PHE 155.A O no hydrogen 2.836 N/A GLN 182.A N.B PHE 155.A O no hydrogen 2.837 N/A GLN 182.A NE2.A PRO 179.A O no hydrogen 2.628 N/A GLN 182.A NE2.A VAL 181.A O no hydrogen 3.641 N/A ILE 184.A N LEU 238.A O no hydrogen 2.912 N/A THR 185.A N VAL 157.A O.A no hydrogen 2.864 N/A THR 185.A N VAL 157.A O.B no hydrogen 2.677 N/A THR 185.A OG1 GLU 128.A OE2 no hydrogen 2.818 N/A CYS 186.A N PHE 240.A O no hydrogen 2.890 N/A CYS 186.A SG ASN 226.A O no hydrogen 3.832 N/A ILE 187.A N CYS 242.A O no hydrogen 2.801 N/A ASN 188.A N MET 159.A O no hydrogen 2.850 N/A ASN 188.A ND2 ASN 130.A OD1 no hydrogen 3.481 N/A ASN 188.A ND2 SER 132.A OG no hydrogen 2.928 N/A SER 189.A N ASN 188.A OD1 no hydrogen 2.839 N/A SER 189.A OG ASN 188.A OD1 no hydrogen 3.514 N/A ILE 190.A N LEU 214.A O no hydrogen 3.108 N/A GLY 193.A N GLY 212.A O no hydrogen 2.842 N/A ASP 197.A N SER 202.A O no hydrogen 2.867 N/A GLU 199.A N ASP 197.A OD1 no hydrogen 2.759 N/A THR 200.A N ASP 197.A OD1 no hydrogen 3.305 N/A THR 200.A OG1 SER 202.A OG no hydrogen 2.763 N/A SER 202.A OG THR 200.A OG1 no hydrogen 2.763 N/A SER 202.A OG VAL 203.A O no hydrogen 2.875 N/A LYS 206.A N PRO 59.A O no hydrogen 2.798 N/A LYS 208.A NZ ASN 192.A OD1 no hydrogen 2.609 N/A GLY 210.A N PRO 207.A O no hydrogen 2.999 N/A PHE 211.A N LYS 208.A O no hydrogen 3.074 N/A GLY 212.A N GLY 193.A O no hydrogen 2.964 N/A GLY 213.A N ASN 70.A O no hydrogen 2.801 N/A LEU 214.A N ILE 190.A O no hydrogen 2.804 N/A GLY 215.A N SER 68.A O no hydrogen 2.997 N/A TYR 218.A N LEU 66.A O no hydrogen 3.094 N/A VAL 219.A N GLY 216.A O no hydrogen 2.976 N/A ALA 223.A N VAL 219.A O no hydrogen 2.832 N/A LEU 224.A N LEU 220.A O no hydrogen 2.851 N/A ALA 225.A N PRO 221.A O no hydrogen 2.976 N/A ASN 226.A N THR 222.A O no hydrogen 3.049 N/A ASN 226.A ND2 TYR 162.A O no hydrogen 3.165 N/A ASN 226.A ND2 THR 222.A O no hydrogen 2.897 N/A ILE 227.A N ALA 223.A O no hydrogen 2.855 N/A ASN 228.A N LEU 224.A O no hydrogen 2.927 N/A ALA 229.A N ALA 225.A O no hydrogen 2.802 N/A PHE 230.A N ASN 226.A O no hydrogen 3.012 N/A TYR 231.A N ILE 227.A O no hydrogen 2.889 N/A ARG 232.A N ASN 228.A O no hydrogen 2.952 N/A ARG 233.A N ALA 229.A O no hydrogen 3.023 N/A ARG 233.A NE ASP 169.A OD1 no hydrogen 2.726 N/A ARG 233.A NH1 ALA 229.A O no hydrogen 3.135 N/A CYS 234.A N PHE 230.A O no hydrogen 2.791 N/A CYS 234.A SG ASN 176.A OD1 no hydrogen 3.480 N/A LYS 237.A N CYS 234.A O no hydrogen 2.987 N/A LYS 237.A NZ LEU 175.A O no hydrogen 3.160 N/A LYS 237.A NZ PHE 178.A O no hydrogen 2.990 N/A LYS 237.A NZ VAL 181.A O no hydrogen 2.806 N/A LEU 238.A N GLN 182.A O.A no hydrogen 2.811 N/A LEU 238.A N GLN 182.A O.B no hydrogen 3.084 N/A PHE 240.A N ILE 184.A O no hydrogen 2.786 N/A GLY 241.A N MET 261.A O no hydrogen 2.846 N/A CYS 242.A N CYS 186.A O no hydrogen 2.793 N/A CYS 242.A SG ILE 187.A O no hydrogen 3.673 N/A CYS 242.A SG GLN 263.A OE1 no hydrogen 3.561 N/A TYR 246.A N ASP 250.A OD2 no hydrogen 2.888 N/A THR 247.A N ASP 250.A OD2 no hydrogen 3.127 N/A GLY 248.A N GLU 282.A OE1 no hydrogen 2.819 N/A ASP 250.A N THR 247.A OG1 no hydrogen 3.040 N/A ALA 251.A N THR 247.A O no hydrogen 3.092 N/A PHE 252.A N GLY 248.A O no hydrogen 2.875 N/A LEU 253.A N GLU 249.A O no hydrogen 3.029 N/A HIS 254.A N ASP 250.A O no hydrogen 3.055 N/A HIS 254.A NE2 GLY 243.A O no hydrogen 2.869 N/A VAL 255.A N ALA 251.A O no hydrogen 3.021 N/A LEU 256.A N PHE 252.A O no hydrogen 2.882 N/A ALA 257.A N LEU 253.A O no hydrogen 2.974 N/A GLY 258.A N VAL 255.A O no hydrogen 2.898 N/A ALA 259.A N HIS 254.A O no hydrogen 2.910 N/A SER 260.A N ILE 239.A O no hydrogen 2.761 N/A VAL 262.A N PRO 17.A O no hydrogen 2.778 N/A GLN 263.A N GLY 241.A O no hydrogen 2.744 N/A GLN 263.A NE2 GLU 128.A OE2 no hydrogen 3.150 N/A VAL 264.A N MET 19.A O no hydrogen 2.944 N/A THR 266.A OG1 SER 68.A OG no hydrogen 2.718 N/A GLN 269.A N GLY 265.A O no hydrogen 2.877 N/A GLU 270.A N THR 266.A O no hydrogen 3.041 N/A GLU 271.A N ALA 267.A O no hydrogen 3.023 N/A GLU 271.A N LEU 268.A O no hydrogen 3.217 N/A GLY 272.A N LEU 268.A O no hydrogen 2.768 N/A ILE 275.A N GLY 272.A O no hydrogen 2.932 N/A PHE 276.A N PRO 273.A O no hydrogen 3.253 N/A GLU 277.A N SER 274.A O no hydrogen 3.172 N/A ARG 278.A NE GLU 271.A OE2 no hydrogen 2.930 N/A ARG 278.A NH1 TYR 246.A O no hydrogen 2.930 N/A ARG 278.A NH1 GLU 282.A OE2 no hydrogen 2.904 N/A ARG 278.A NH2 TYR 246.A O no hydrogen 2.865 N/A ARG 278.A NH2 GLU 271.A OE1 no hydrogen 2.815 N/A LEU 279.A N ILE 275.A O no hydrogen 2.807 N/A THR 280.A N PHE 276.A O no hydrogen 3.021 N/A THR 280.A OG1 PHE 276.A O no hydrogen 3.030 N/A THR 280.A OG1 GLU 277.A O no hydrogen 3.064 N/A SER 281.A N GLU 277.A O no hydrogen 3.194 N/A GLU 282.A N ARG 278.A O no hydrogen 2.844 N/A LEU 283.A N LEU 279.A O no hydrogen 2.849 N/A LEU 284.A N THR 280.A O no hydrogen 2.993 N/A GLY 285.A N SER 281.A O no hydrogen 2.959 N/A VAL 286.A N GLU 282.A O no hydrogen 2.843 N/A MET 287.A N LEU 283.A O no hydrogen 2.935 N/A ALA 288.A N LEU 284.A O no hydrogen 2.804 N/A LYS 289.A N GLY 285.A O no hydrogen 3.119 N/A LYS 290.A N.A VAL 286.A O no hydrogen 3.101 N/A LYS 290.A N.B VAL 286.A O no hydrogen 3.090 N/A LYS 290.A N.B MET 287.A O no hydrogen 3.171 N/A ARG 291.A N ALA 288.A O no hydrogen 3.134 N/A TYR 292.A N MET 287.A O no hydrogen 2.861 N/A GLN 293.A N GLU 297.A OE1 no hydrogen 2.547 N/A THR 294.A N GLU 297.A OE1 no hydrogen 2.968 N/A GLU 297.A N THR 294.A O no hydrogen 3.349 N/A PHE 298.A N LEU 295.A O no hydrogen 3.181 N/A ARG 299.A N LEU 295.A O no hydrogen 2.981 N/A ARG 299.A NE ALA 259.A O no hydrogen 3.118 N/A ARG 299.A NH1 ASP 296.A OD1 no hydrogen 2.683 N/A GLY 300.A N VAL 255.A O no hydrogen 2.892 N/A LYS 301.A N PHE 298.A O no hydrogen 2.999 N/A LYS 301.A NZ GLU 297.A O no hydrogen 3.153 N/A VAL 302.A N LEU 256.A O no hydrogen 3.179 N/A