Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4acb_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LYS 5.A N ASN 42.A O no hydrogen 2.787 N/A ASN 6.A ND2 ASP 230.A OD1 no hydrogen 2.769 N/A ILE 7.A N ARG 44.A O no hydrogen 2.730 N/A ASN 8.A N ASP 68.A OD2 no hydrogen 2.956 N/A ASN 8.A ND2 GLY 229.A O no hydrogen 3.070 N/A LEU 9.A N THR 46.A O no hydrogen 3.179 N/A GLY 10.A N LEU 69.A O no hydrogen 2.881 N/A ILE 11.A N VAL 48.A O no hydrogen 3.008 N/A PHE 12.A N LEU 71.A O no hydrogen 2.806 N/A HIS 17.A N HIS 14.A O no hydrogen 3.124 N/A LYS 19.A NZ GLY 13.A O no hydrogen 3.568 N/A LYS 19.A NZ HIS 14.A O no hydrogen 2.989 N/A THR 20.A OG1 THR 30.A OG1 no hydrogen 3.024 N/A THR 20.A OG1 ASP 49.A OD2 no hydrogen 3.390 N/A LEU 22.A N GLY 18.A O no hydrogen 3.159 N/A SER 23.A N LYS 19.A O no hydrogen 2.771 N/A SER 23.A OG LYS 19.A O no hydrogen 3.347 N/A SER 23.A OG ASP 49.A OD2 no hydrogen 3.013 N/A LYS 24.A N THR 20.A O no hydrogen 2.865 N/A VAL 25.A N THR 21.A O no hydrogen 3.075 N/A LEU 26.A N LEU 22.A O no hydrogen 3.060 N/A THR 27.A N SER 23.A O no hydrogen 2.928 N/A THR 27.A OG1 SER 23.A O no hydrogen 2.592 N/A ILE 29.A N LEU 26.A O no hydrogen 3.509 N/A THR 30.A OG1 THR 20.A OG1 no hydrogen 3.024 N/A ILE 33.A N ASP 32.A OD1 no hydrogen 2.410 N/A GLY 34.A N ASP 49.A O no hydrogen 2.744 N/A SER 36.A N LEU 47.A O no hydrogen 3.118 N/A PHE 38.A N ILE 45.A O no hydrogen 2.812 N/A LEU 40.A N TYR 43.A O no hydrogen 3.006 N/A ASN 42.A ND2 ASP 3.A O no hydrogen 3.313 N/A ASN 42.A ND2 ASN 42.A O no hydrogen 2.808 N/A TYR 43.A N LEU 40.A O no hydrogen 2.851 N/A TYR 43.A OH ASN 158.A OD1 no hydrogen 2.595 N/A ARG 44.A N LYS 5.A O no hydrogen 2.798 N/A ARG 44.A NH1 ASN 6.A OD1 no hydrogen 2.825 N/A ARG 44.A NH1 TYR 218.A OH no hydrogen 3.425 N/A ILE 45.A N PHE 38.A O no hydrogen 2.742 N/A THR 46.A N ILE 7.A O no hydrogen 2.717 N/A LEU 47.A N SER 36.A O no hydrogen 2.516 N/A VAL 48.A N LEU 9.A O no hydrogen 2.857 N/A ASP 49.A N GLY 34.A O no hydrogen 2.726 N/A ALA 50.A N ILE 11.A O no hydrogen 3.090 N/A LEU 56.A N HIS 53.A O no hydrogen 3.356 N/A ALA 59.A N LEU 56.A O no hydrogen 2.779 N/A VAL 61.A N ILE 57.A O no hydrogen 2.953 N/A SER 62.A N ARG 58.A O no hydrogen 3.235 N/A SER 62.A OG ARG 58.A O no hydrogen 2.606 N/A SER 62.A OG MET 288.A O no hydrogen 3.496 N/A ALA 63.A N VAL 60.A O no hydrogen 3.044 N/A ALA 64.A N VAL 61.A O no hydrogen 3.007 N/A ASP 68.A N ASN 8.A O no hydrogen 3.156 N/A ALA 70.A N PRO 97.A O no hydrogen 3.052 N/A LEU 71.A N GLY 10.A O no hydrogen 2.943 N/A ILE 72.A N ILE 99.A O no hydrogen 3.240 N/A VAL 73.A N PHE 12.A O no hydrogen 2.775 N/A VAL 74.A N VAL 101.A O no hydrogen 3.027 N/A ALA 76.A N THR 103.A O no hydrogen 2.903 N/A LYS 77.A N ASP 75.A OD1 no hydrogen 3.199 N/A LYS 81.A N THR 84.A OG1 no hydrogen 3.410 N/A THR 82.A OG1 THR 347.A O no hydrogen 3.369 N/A THR 84.A N LYS 81.A O no hydrogen 2.986 N/A GLY 85.A N THR 82.A O no hydrogen 3.237 N/A HIS 87.A N GLN 83.A O no hydrogen 2.960 N/A MET 88.A N THR 84.A O no hydrogen 3.014 N/A LEU 89.A N GLY 85.A O no hydrogen 2.549 N/A ILE 90.A N GLU 86.A O no hydrogen 2.770 N/A LEU 91.A N HIS 87.A O no hydrogen 3.074 N/A ASP 92.A N MET 88.A O no hydrogen 3.046 N/A HIS 93.A N LEU 89.A O no hydrogen 2.868 N/A HIS 93.A ND1 LEU 89.A O no hydrogen 2.440 N/A HIS 93.A NE2 SER 269.A OG no hydrogen 2.362 N/A PHE 94.A N ILE 90.A O no hydrogen 3.167 N/A ASN 95.A N ASP 92.A O no hydrogen 3.330 N/A ILE 96.A N LEU 91.A O no hydrogen 2.870 N/A ILE 99.A N ALA 70.A O no hydrogen 3.158 N/A VAL 100.A N SER 134.A O no hydrogen 3.200 N/A VAL 101.A N ILE 72.A O no hydrogen 2.874 N/A ILE 102.A N ILE 136.A O no hydrogen 2.746 N/A THR 103.A N VAL 74.A O no hydrogen 3.032 N/A THR 103.A OG1 HIS 17.A O no hydrogen 2.413 N/A LYS 104.A NZ ASP 16.A O no hydrogen 2.812 N/A SER 105.A N ILE 138.A O no hydrogen 3.281 N/A SER 105.A OG ILE 138.A O no hydrogen 2.386 N/A ASN 107.A N LYS 104.A O no hydrogen 3.198 N/A ALA 108.A N SER 105.A O no hydrogen 3.490 N/A ILE 113.A N GLY 109.A O no hydrogen 3.071 N/A LYS 114.A N THR 110.A O no hydrogen 3.041 N/A ARG 115.A N GLU 111.A O no hydrogen 2.940 N/A THR 116.A N GLU 112.A O no hydrogen 3.243 N/A THR 116.A OG1 ALA 76.A O no hydrogen 2.513 N/A THR 116.A OG1 GLU 112.A O no hydrogen 3.115 N/A GLU 117.A N ILE 113.A O no hydrogen 2.661 N/A MET 118.A N LYS 114.A O no hydrogen 2.995 N/A ILE 119.A N ARG 115.A O no hydrogen 2.891 N/A MET 120.A N THR 116.A O no hydrogen 3.009 N/A LYS 121.A N GLU 117.A O no hydrogen 3.116 N/A SER 122.A N MET 118.A O no hydrogen 2.820 N/A ILE 123.A N ILE 119.A O no hydrogen 3.139 N/A LEU 124.A N MET 120.A O no hydrogen 2.827 N/A GLN 125.A N SER 122.A O no hydrogen 3.273 N/A SER 126.A N ILE 123.A O no hydrogen 2.752 N/A SER 126.A OG SER 122.A O no hydrogen 3.427 N/A THR 127.A N LEU 124.A O no hydrogen 3.305 N/A THR 127.A OG1 LEU 124.A O no hydrogen 3.009 N/A HIS 128.A N ASP 92.A OD2 no hydrogen 2.993 N/A ASN 129.A N ASP 92.A OD1 no hydrogen 2.799 N/A ASN 129.A ND2 ASP 92.A O no hydrogen 2.882 N/A LEU 130.A N ASP 92.A OD1 no hydrogen 3.167 N/A LYS 131.A NZ THR 127.A O no hydrogen 2.937 N/A ASN 132.A ND2 ASN 132.A O no hydrogen 2.804 N/A SER 133.A OG LEU 130.A O no hydrogen 2.979 N/A ILE 136.A N VAL 100.A O no hydrogen 3.115 N/A ILE 138.A N ILE 102.A O no hydrogen 2.724 N/A SER 139.A N PHE 144.A O no hydrogen 3.105 N/A THR 142.A N SER 139.A OG no hydrogen 2.908 N/A GLY 143.A N SER 139.A O no hydrogen 2.522 N/A VAL 146.A N GLY 143.A O no hydrogen 3.155 N/A LEU 149.A N GLY 145.A O no hydrogen 3.034 N/A LYS 150.A N VAL 146.A O no hydrogen 3.212 N/A ASN 151.A N ASP 147.A O no hydrogen 3.353 N/A LEU 152.A N GLU 148.A O no hydrogen 2.932 N/A ILE 153.A N LEU 149.A O no hydrogen 3.075 N/A ILE 154.A N LYS 150.A O no hydrogen 2.993 N/A THR 155.A N ASN 151.A O no hydrogen 3.255 N/A THR 155.A OG1 ASN 151.A O no hydrogen 2.763 N/A THR 156.A N LEU 152.A O no hydrogen 2.777 N/A THR 156.A OG1 LEU 152.A O no hydrogen 2.656 N/A LEU 157.A N ILE 153.A O no hydrogen 3.211 N/A ASN 158.A N ILE 154.A O no hydrogen 2.913 N/A ASN 159.A N THR 155.A O no hydrogen 3.020 N/A ASN 159.A N THR 156.A O no hydrogen 3.250 N/A ALA 160.A N THR 156.A O no hydrogen 2.846 N/A ARG 164.A NH1 ASP 68.A OD1 no hydrogen 2.963 N/A ARG 164.A NH2 ASN 6.A O no hydrogen 2.876 N/A ARG 164.A NH2 ASP 68.A OD1 no hydrogen 2.781 N/A THR 166.A OG1 GLU 167.A OE2 no hydrogen 2.797 N/A TYR 169.A OH GLU 332.A OE1 no hydrogen 2.616 N/A LYS 171.A N LYS 193.A O no hydrogen 3.127 N/A MET 172.A N LEU 249.A O no hydrogen 2.747 N/A ASP 175.A N THR 188.A O no hydrogen 2.983 N/A HIS 176.A NE2 ASP 32.A OD2 no hydrogen 2.783 N/A PHE 178.A N VAL 186.A O no hydrogen 2.911 N/A GLY 184.A N LYS 181.A O no hydrogen 3.170 N/A THR 185.A N ILE 236.A O no hydrogen 3.089 N/A THR 185.A OG1 GLY 184.A O no hydrogen 2.777 N/A THR 185.A OG1 VAL 239.A O no hydrogen 2.871 N/A VAL 186.A N PHE 178.A O no hydrogen 2.969 N/A VAL 187.A N MET 234.A O no hydrogen 2.601 N/A THR 188.A N HIS 176.A O no hydrogen 3.093 N/A THR 188.A OG1 HIS 176.A O no hydrogen 3.256 N/A GLY 189.A N VAL 232.A O no hydrogen 3.377 N/A ILE 191.A N ASP 230.A O no hydrogen 3.007 N/A ASN 192.A N LYS 171.A O no hydrogen 2.989 N/A LYS 193.A N LYS 171.A O no hydrogen 3.371 N/A LYS 193.A NZ GLU 332.A OE1 no hydrogen 2.661 N/A GLY 194.A N ASN 165.A O no hydrogen 2.612 N/A VAL 196.A N ALA 226.A O no hydrogen 3.118 N/A LYS 197.A N ASP 200.A OD2 no hydrogen 2.756 N/A VAL 198.A N MET 224.A O no hydrogen 2.780 N/A GLY 199.A N VAL 213.A O no hydrogen 2.649 N/A LEU 202.A N THR 211.A O no hydrogen 2.674 N/A LYS 203.A N THR 250.A O no hydrogen 3.044 N/A VAL 204.A N MET 209.A O no hydrogen 3.302 N/A MET 209.A N VAL 204.A O no hydrogen 3.214 N/A THR 211.A N LEU 202.A O no hydrogen 2.953 N/A LYS 212.A N GLN 237.A O no hydrogen 3.227 N/A VAL 213.A N ASP 200.A O no hydrogen 2.836 N/A ARG 214.A N ALA 235.A O no hydrogen 2.745 N/A SER 215.A N ALA 235.A O no hydrogen 3.370 N/A GLN 217.A N GLY 233.A O no hydrogen 2.711 N/A TYR 218.A N GLU 221.A O no hydrogen 2.743 N/A TYR 218.A OH ASN 6.A OD1 no hydrogen 2.510 N/A VAL 223.A N ILE 216.A O no hydrogen 2.985 N/A ALA 226.A N VAL 196.A O no hydrogen 2.845 N/A GLY 229.A N ILE 191.A O no hydrogen 2.724 N/A ASP 230.A N LYS 227.A O no hydrogen 3.249 N/A ARG 231.A NH1 ASP 175.A OD2 no hydrogen 2.583 N/A ARG 231.A NH1 THR 190.A OG1 no hydrogen 3.016 N/A ARG 231.A NH2 ASP 175.A OD2 no hydrogen 2.427 N/A VAL 232.A N GLY 189.A O no hydrogen 3.356 N/A GLY 233.A N GLN 217.A O no hydrogen 2.623 N/A MET 234.A N VAL 187.A O no hydrogen 2.811 N/A ALA 235.A N SER 215.A O no hydrogen 3.118 N/A ILE 236.A N THR 185.A O no hydrogen 2.926 N/A GLN 237.A N LYS 212.A O no hydrogen 3.061 N/A ASP 240.A N ASP 240.A OD1 no hydrogen 2.297 N/A GLN 243.A N ASP 240.A O no hydrogen 3.352 N/A GLN 243.A NE2 ASP 240.A OD2 no hydrogen 3.538 N/A LEU 249.A N MET 172.A O no hydrogen 2.523 N/A THR 250.A N LYS 203.A O no hydrogen 3.096 N/A THR 250.A OG1 PHE 170.A O no hydrogen 2.414 N/A THR 250.A OG1 SER 251.A O no hydrogen 3.522 N/A SER 251.A N PHE 170.A O no hydrogen 2.998 N/A LYS 252.A NZ GLU 201.A OE1 no hydrogen 2.900 N/A THR 254.A OG1 THR 250.A OG1 no hydrogen 3.424 N/A LEU 256.A N THR 254.A OG1 no hydrogen 2.877 N/A GLN 257.A N ALA 331.A O no hydrogen 3.040 N/A VAL 259.A N VAL 329.A O no hydrogen 2.614 N/A ILE 262.A N PHE 323.A O no hydrogen 3.003 N/A VAL 263.A N GLU 358.A O no hydrogen 2.684 N/A LYS 265.A N LEU 355.A O no hydrogen 2.752 N/A LYS 267.A N HIS 353.A O no hydrogen 2.855 N/A SER 269.A OG HIS 93.A NE2 no hydrogen 2.362 N/A PHE 272.A N ASP 270.A OD1 no hydrogen 3.373 N/A TYR 274.A N ILE 271.A O no hydrogen 2.625 N/A THR 277.A N ASN 275.A OD1 no hydrogen 2.714 N/A THR 277.A OG1 ASN 275.A OD1 no hydrogen 3.031 N/A MET 280.A N ALA 295.A O no hydrogen 2.916 N/A VAL 282.A N ALA 293.A O no hydrogen 3.173 N/A HIS 283.A N THR 340.A O no hydrogen 2.917 N/A LEU 284.A N VAL 291.A O no hydrogen 2.829 N/A ASN 285.A N LEU 338.A O no hydrogen 2.756 N/A LEU 289.A N VAL 286.A O no hydrogen 3.038 N/A VAL 291.A N LEU 284.A O no hydrogen 3.086 N/A ALA 293.A N VAL 282.A O no hydrogen 2.828 N/A VAL 294.A N GLU 324.A O no hydrogen 3.033 N/A ALA 295.A N MET 280.A O no hydrogen 3.056 N/A VAL 296.A N ALA 322.A O no hydrogen 3.095 N/A PHE 298.A N TYR 321.A O no hydrogen 2.718 N/A LYS 299.A N ILE 310.A O no hydrogen 2.629 N/A LYS 300.A NZ ASN 309.A OD1 no hydrogen 3.237 N/A VAL 301.A N GLU 308.A O no hydrogen 3.123 N/A GLU 308.A N VAL 301.A O no hydrogen 3.405 N/A ASN 309.A ND2 LEU 365.A O no hydrogen 2.863 N/A ILE 310.A N LYS 299.A O no hydrogen 2.759 N/A ILE 311.A N LYS 368.A O no hydrogen 3.008 N/A LEU 312.A N PRO 297.A O no hydrogen 3.349 N/A VAL 315.A N ASN 313.A OD1 no hydrogen 3.264 N/A PHE 323.A N ILE 262.A O no hydrogen 2.538 N/A GLU 324.A N VAL 294.A O no hydrogen 2.879 N/A LEU 325.A N ASP 260.A O no hydrogen 3.056 N/A GLU 326.A N PRO 292.A O no hydrogen 3.175 N/A VAL 329.A N VAL 259.A O no hydrogen 3.202 N/A ALA 331.A N GLN 257.A O no hydrogen 2.948 N/A GLU 332.A N ASP 335.A OD2 no hydrogen 2.713 N/A GLY 334.A N ILE 356.A O no hydrogen 2.763 N/A VAL 337.A N GLY 354.A O no hydrogen 2.506 N/A LEU 338.A N ASN 285.A O no hydrogen 3.125 N/A ILE 339.A N GLY 352.A O no hydrogen 2.818 N/A THR 340.A N HIS 283.A O no hydrogen 3.253 N/A THR 340.A OG1 HIS 283.A O no hydrogen 2.811 N/A ARG 341.A N ARG 350.A O no hydrogen 3.078 N/A ARG 341.A NE ASP 343.A OD2 no hydrogen 3.014 N/A THR 348.A N PRO 345.A O no hydrogen 3.360 N/A ARG 350.A NH1 LEU 342.A O no hydrogen 3.297 N/A ARG 350.A NH1 LEU 344.A O no hydrogen 3.372 N/A ARG 350.A NH2 ALA 54.A O no hydrogen 2.323 N/A HIS 353.A N LYS 267.A O no hydrogen 3.095 N/A GLY 354.A N VAL 337.A O no hydrogen 2.821 N/A ILE 356.A N ASP 335.A O no hydrogen 3.089 N/A GLU 357.A N VAL 263.A O no hydrogen 2.862 N/A GLU 358.A N VAL 263.A O no hydrogen 3.064 N/A LYS 360.A NZ ASP 364.A O no hydrogen 2.948 N/A ASP 364.A N PRO 361.A O no hydrogen 3.156 N/A LEU 365.A N ILE 362.A O no hydrogen 3.157 N/A LYS 368.A N ASN 309.A O no hydrogen 2.829 N/A LYS 368.A NZ GLU 308.A OE2 no hydrogen 2.897 N/A LYS 369.A N ARG 445.A O no hydrogen 2.819 N/A VAL 371.A N ARG 443.A O no hydrogen 2.992 N/A ARG 373.A N LEU 441.A O no hydrogen 3.381 N/A GLY 375.A N VAL 439.A O no hydrogen 3.027 N/A LYS 376.A N ASP 387.A O no hydrogen 2.639 N/A VAL 377.A N ASP 437.A O no hydrogen 3.025 N/A LYS 378.A N VAL 385.A O no hydrogen 2.759 N/A ILE 379.A N ASN 435.A OD1 no hydrogen 3.298 N/A ASP 380.A N ARG 383.A O no hydrogen 3.067 N/A LYS 381.A N ASP 380.A OD1 no hydrogen 2.651 N/A VAL 385.A N LYS 378.A O no hydrogen 2.901 N/A ILE 386.A N LEU 425.A O no hydrogen 2.822 N/A ASP 387.A N LYS 376.A O no hydrogen 2.765 N/A SER 392.A OG GLN 391.A O no hydrogen 2.644 N/A ALA 396.A N SER 392.A O no hydrogen 2.985 N/A GLU 397.A N LYS 393.A O no hydrogen 2.912 N/A LYS 398.A N VAL 394.A O no hydrogen 3.058 N/A LEU 399.A N ALA 396.A O no hydrogen 2.995 N/A ILE 400.A N GLU 397.A O no hydrogen 3.424 N/A GLY 401.A N ILE 415.A O no hydrogen 2.599 N/A GLU 402.A N LEU 399.A O no hydrogen 3.232 N/A ILE 404.A N GLY 413.A O no hydrogen 3.408 N/A SER 405.A N ILE 440.A O no hydrogen 3.366 N/A ILE 406.A N ILE 411.A O no hydrogen 3.461 N/A GLU 407.A N LYS 438.A O no hydrogen 3.103 N/A LYS 409.A N ILE 406.A O no hydrogen 3.428 N/A LYS 409.A NZ GLU 434.A OE1 no hydrogen 2.715 N/A LYS 409.A NZ ASP 437.A OD1 no hydrogen 2.796 N/A LYS 409.A NZ ASP 437.A OD2 no hydrogen 2.907 N/A GLY 413.A N ILE 404.A O no hydrogen 3.132 N/A LYS 414.A N GLU 428.A O no hydrogen 2.879 N/A LYS 416.A N THR 426.A O no hydrogen 3.219 N/A PHE 419.A N LEU 424.A O no hydrogen 2.941 N/A LEU 425.A N ILE 386.A O no hydrogen 2.923 N/A THR 426.A N GLY 417.A O no hydrogen 2.942 N/A GLU 428.A N LYS 414.A O no hydrogen 2.819 N/A SER 430.A N VAL 412.A O no hydrogen 3.137 N/A SER 430.A OG VAL 412.A O no hydrogen 2.807 N/A ARG 436.A N VAL 377.A O no hydrogen 2.889 N/A LYS 438.A NZ ARG 436.A O no hydrogen 2.349 N/A VAL 439.A N GLY 375.A O no hydrogen 2.970 N/A ILE 440.A N SER 405.A O no hydrogen 2.882 N/A LEU 441.A N ARG 373.A O no hydrogen 3.062 N/A ARG 443.A N VAL 371.A O no hydrogen 3.243 N/A ARG 443.A NH1 GLU 402.A OE2 no hydrogen 3.001 N/A ARG 445.A N LYS 369.A O no hydrogen 2.879 N/A