Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4c4h_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): SER 2.A OG TYR 10.A O no hydrogen 2.886 N/A MET 3.A N TYR 10.A O no hydrogen 2.929 N/A SER 4.A OG ARG 8.A O no hydrogen 3.347 N/A VAL 5.A N ARG 8.A O no hydrogen 2.954 N/A LYS 6.A N GLU 76.A OE2 no hydrogen 2.960 N/A LYS 6.A NZ ASP 74.A OD1 no hydrogen 3.433 N/A LYS 6.A NZ TYR 75.A O no hydrogen 2.876 N/A TYR 10.A N MET 3.A O no hydrogen 2.773 N/A SER 11.A N LEU 27.A O no hydrogen 2.812 N/A ILE 12.A N GLN 1.A O no hydrogen 3.477 N/A LEU 13.A N GLN 25.A O no hydrogen 2.809 N/A GLN 15.A NE2 GLY 17.A O no hydrogen 3.010 N/A ILE 16.A N VAL 23.A O no hydrogen 2.803 N/A GLY 17.A N VAL 23.A O no hydrogen 3.388 N/A SER 20.A OG TYR 52.A OH no hydrogen 3.292 N/A LYS 22.A N TYR 38.A O no hydrogen 2.808 N/A VAL 23.A N GLY 17.A O no hydrogen 3.018 N/A PHE 24.A N ILE 36.A O no hydrogen 2.849 N/A GLN 25.A N LYS 14.A O no hydrogen 2.844 N/A VAL 26.A N TYR 34.A O no hydrogen 2.861 N/A LEU 27.A N SER 11.A O no hydrogen 2.834 N/A ASN 28.A N GLN 32.A O no hydrogen 3.001 N/A LYS 30.A N ASN 28.A OD1 no hydrogen 2.929 N/A LYS 31.A N ASN 28.A O no hydrogen 2.943 N/A GLN 32.A N ASN 28.A OD1 no hydrogen 2.833 N/A TYR 34.A N VAL 26.A O no hydrogen 3.207 N/A TYR 34.A OH GLN 32.A OE1 no hydrogen 2.934 N/A ALA 35.A N MET 86.A O no hydrogen 2.906 N/A ILE 36.A N PHE 24.A O no hydrogen 2.920 N/A LYS 37.A N MET 84.A O no hydrogen 3.023 N/A TYR 38.A N LYS 22.A O no hydrogen 2.806 N/A VAL 39.A N ILE 82.A O no hydrogen 2.810 N/A ASN 40.A N SER 20.A O no hydrogen 3.140 N/A LEU 41.A N GLN 80.A O no hydrogen 2.812 N/A ALA 44.A N LEU 41.A O no hydrogen 3.222 N/A THR 48.A N ASP 45.A OD2 no hydrogen 3.205 N/A THR 48.A OG1 ASP 45.A OD1 no hydrogen 2.718 N/A THR 48.A OG1 ASP 45.A OD2 no hydrogen 2.967 N/A LEU 49.A N ASP 45.A O no hydrogen 2.967 N/A ASP 50.A N ASN 46.A O no hydrogen 2.916 N/A SER 51.A N GLN 47.A O no hydrogen 3.118 N/A SER 51.A OG THR 48.A O no hydrogen 2.790 N/A TYR 52.A N THR 48.A O no hydrogen 3.170 N/A TYR 52.A OH SER 20.A OG no hydrogen 3.292 N/A ARG 53.A N LEU 49.A O no hydrogen 3.138 N/A ARG 53.A NH1 ASP 50.A OD1 no hydrogen 3.265 N/A ASN 54.A N ASP 50.A O no hydrogen 2.870 N/A GLU 55.A N SER 51.A O no hydrogen 3.092 N/A ILE 56.A N TYR 52.A O no hydrogen 3.220 N/A ALA 57.A N ARG 53.A O no hydrogen 3.085 N/A TYR 58.A N ASN 54.A O no hydrogen 3.045 N/A LEU 59.A N GLU 55.A O no hydrogen 2.800 N/A ASN 60.A N ILE 56.A O no hydrogen 2.798 N/A LYS 61.A N ALA 57.A O no hydrogen 2.972 N/A LEU 62.A N TYR 58.A O no hydrogen 2.929 N/A HIS 65.A N LEU 62.A O no hydrogen 3.103 N/A HIS 65.A ND1 LYS 61.A O no hydrogen 2.959 N/A SER 66.A N LEU 62.A O no hydrogen 3.273 N/A SER 66.A OG GLU 117.A OE2 no hydrogen 2.881 N/A LYS 68.A N SER 66.A OG no hydrogen 3.061 N/A LYS 68.A NZ ASP 67.A OD1 no hydrogen 2.806 N/A LYS 68.A NZ GLU 117.A OE1 no hydrogen 2.787 N/A ILE 70.A N LEU 146.A O no hydrogen 3.328 N/A ARG 71.A N GLU 87.A OE2 no hydrogen 2.773 N/A ARG 71.A NH1 GLN 63.A O no hydrogen 2.809 N/A ARG 71.A NH2 GLN 63.A O no hydrogen 3.388 N/A ARG 71.A NH2 SER 66.A O no hydrogen 2.658 N/A ARG 71.A NH2 ILE 69.A O no hydrogen 2.735 N/A LEU 72.A N GLN 63.A OE1 no hydrogen 2.906 N/A TYR 73.A N VAL 85.A O no hydrogen 2.762 N/A ASP 74.A N VAL 85.A O no hydrogen 3.436 N/A GLU 76.A N TYR 83.A O no hydrogen 2.852 N/A THR 78.A N TYR 81.A O no hydrogen 2.965 N/A THR 78.A OG1 GLN 80.A OE1 no hydrogen 3.217 N/A THR 78.A OG1 TYR 81.A O no hydrogen 3.484 N/A GLN 80.A N THR 78.A OG1 no hydrogen 3.300 N/A TYR 81.A N THR 78.A OG1 no hydrogen 3.206 N/A ILE 82.A N VAL 39.A O no hydrogen 2.965 N/A TYR 83.A N GLU 76.A O no hydrogen 2.806 N/A MET 84.A N LYS 37.A O no hydrogen 2.911 N/A VAL 85.A N ASP 74.A O no hydrogen 2.814 N/A MET 86.A N ALA 35.A O no hydrogen 2.970 N/A GLU 87.A N ARG 71.A O no hydrogen 3.182 N/A CYS 88.A SG GLY 89.A O no hydrogen 3.934 N/A ASN 90.A N ILE 139.A O no hydrogen 2.760 N/A LEU 93.A N PHE 137.A O no hydrogen 2.768 N/A SER 95.A N ASP 92.A OD2 no hydrogen 2.805 N/A SER 95.A OG ASP 92.A OD1 no hydrogen 2.874 N/A SER 95.A OG ASP 92.A OD2 no hydrogen 3.100 N/A TRP 96.A N ASP 92.A O no hydrogen 3.099 N/A TRP 96.A NE1 GLU 107.A OE2 no hydrogen 3.106 N/A LEU 97.A N LEU 93.A O no hydrogen 2.944 N/A LYS 98.A N ASN 94.A O no hydrogen 2.996 N/A LYS 99.A N SER 95.A O no hydrogen 3.046 N/A LYS 100.A N TRP 96.A O no hydrogen 2.790 N/A ARG 108.A N ASP 104.A O no hydrogen 2.947 N/A ARG 108.A NH1 MET 181.A O no hydrogen 2.737 N/A LYS 109.A NZ TYR 244.A O no hydrogen 2.784 N/A LYS 109.A NZ ILE 247.A O no hydrogen 2.826 N/A SER 110.A N TRP 106.A O no hydrogen 3.022 N/A TYR 111.A N GLU 107.A O no hydrogen 2.994 N/A TYR 111.A OH GLU 107.A OE2 no hydrogen 3.263 N/A TRP 112.A N ARG 108.A O no hydrogen 2.819 N/A LYS 113.A N LYS 109.A O no hydrogen 3.109 N/A ASN 114.A N SER 110.A O no hydrogen 3.331 N/A MET 115.A N TYR 111.A O no hydrogen 3.101 N/A LEU 116.A N TRP 112.A O no hydrogen 3.113 N/A GLU 117.A N LYS 113.A O no hydrogen 2.881 N/A ALA 118.A N ASN 114.A O no hydrogen 2.993 N/A VAL 119.A N MET 115.A O no hydrogen 2.953 N/A HIS 120.A N LEU 116.A O no hydrogen 2.770 N/A THR 121.A N GLU 117.A O no hydrogen 3.029 N/A THR 121.A OG1 GLU 117.A O no hydrogen 2.684 N/A ILE 122.A N ALA 118.A O no hydrogen 3.340 N/A HIS 123.A N VAL 119.A O no hydrogen 3.155 N/A HIS 123.A NE2 ASP 170.A OD2 no hydrogen 2.785 N/A GLN 124.A N HIS 120.A O no hydrogen 3.059 N/A HIS 125.A N ILE 122.A O no hydrogen 3.179 N/A HIS 125.A ND1 THR 121.A O no hydrogen 2.831 N/A GLY 126.A N HIS 123.A O no hydrogen 2.974 N/A ILE 127.A N ILE 122.A O no hydrogen 2.937 N/A HIS 129.A N ASP 170.A OD2 no hydrogen 3.107 N/A SER 130.A N ASP 170.A OD1 no hydrogen 2.929 N/A SER 130.A OG HIS 129.A O no hydrogen 2.666 N/A ASP 131.A N HIS 129.A ND1 no hydrogen 3.192 N/A LYS 133.A N ASN 136.A OD1 no hydrogen 3.366 N/A LYS 133.A NZ ASP 131.A O no hydrogen 3.176 N/A LYS 133.A NZ ASP 131.A OD2 no hydrogen 3.307 N/A LYS 133.A NZ ASN 136.A OD1 no hydrogen 2.888 N/A ASN 136.A N LYS 133.A O no hydrogen 3.056 N/A PHE 137.A N PRO 134.A O no hydrogen 3.030 N/A LEU 138.A N LYS 145.A O no hydrogen 2.749 N/A ILE 139.A N ILE 91.A O no hydrogen 2.778 N/A VAL 140.A N MET 143.A O no hydrogen 2.802 N/A ASP 141.A N ASN 90.A OD1 no hydrogen 3.256 N/A LEU 144.A N ASN 114.A OD1 no hydrogen 2.789 N/A LYS 145.A N LEU 138.A O no hydrogen 2.805 N/A LYS 145.A NZ ASP 67.A O no hydrogen 2.768 N/A LYS 145.A NZ GLU 87.A OE1 no hydrogen 3.538 N/A LYS 145.A NZ GLU 87.A OE2 no hydrogen 2.998 N/A LEU 146.A N LYS 68.A O no hydrogen 2.881 N/A ILE 147.A N ASN 136.A O no hydrogen 2.760 N/A PHE 149.A N GLU 55.A OE1 no hydrogen 3.089 N/A ALA 152.A N GLU 55.A OE2 no hydrogen 2.926 N/A MET 157.A N VAL 154.A O no hydrogen 3.108 N/A GLU 160.A N GLU 160.A OE1 no hydrogen 2.950 N/A ALA 161.A N PRO 158.A O no hydrogen 3.288 N/A ILE 162.A N PRO 159.A O no hydrogen 3.216 N/A LYS 163.A N PRO 159.A O no hydrogen 3.095 N/A SER 166.A N SER 169.A OG no hydrogen 2.987 N/A LYS 168.A NZ PRO 230.A O no hydrogen 3.013 N/A LYS 168.A NZ ARG 233.A O no hydrogen 2.851 N/A SER 169.A N SER 166.A O no hydrogen 2.719 N/A SER 169.A OG GLU 160.A OE2 no hydrogen 3.007 N/A SER 169.A OG SER 166.A O no hydrogen 3.098 N/A TRP 172.A N LYS 168.A O no hydrogen 3.255 N/A SER 173.A N SER 169.A O no hydrogen 3.480 N/A SER 173.A OG TYR 156.A O no hydrogen 2.685 N/A SER 173.A OG SER 169.A O no hydrogen 3.554 N/A LEU 174.A N ASP 170.A O no hydrogen 2.942 N/A GLY 175.A N VAL 171.A O no hydrogen 2.861 N/A CYS 176.A N TRP 172.A O no hydrogen 2.941 N/A CYS 176.A SG ASN 155.A O no hydrogen 3.575 N/A CYS 176.A SG TRP 172.A O no hydrogen 3.489 N/A ILE 177.A N SER 173.A O no hydrogen 3.093 N/A LEU 178.A N LEU 174.A O no hydrogen 2.889 N/A TYR 179.A N GLY 175.A O no hydrogen 2.945 N/A TYR 179.A OH GLU 209.A O no hydrogen 2.711 N/A TYR 180.A N CYS 176.A O no hydrogen 2.934 N/A MET 181.A N ILE 177.A O no hydrogen 3.139 N/A THR 182.A OG1 LEU 178.A O no hydrogen 2.740 N/A TYR 183.A N TYR 179.A O no hydrogen 2.757 N/A TYR 183.A OH PRO 211.A O no hydrogen 2.648 N/A GLY 184.A N TYR 180.A O no hydrogen 2.766 N/A THR 186.A OG1 GLN 189.A OE1 no hydrogen 3.090 N/A GLN 189.A N THR 186.A O no hydrogen 3.203 N/A GLN 190.A N GLN 190.A OE1 no hydrogen 2.830 N/A GLN 190.A NE2 PRO 187.A O no hydrogen 2.978 N/A ILE 191.A N PHE 188.A O no hydrogen 3.427 N/A GLN 194.A NE2 ILE 192.A O no hydrogen 2.767 N/A SER 196.A N ASN 193.A OD1 no hydrogen 3.424 N/A LYS 197.A N ASN 193.A O no hydrogen 2.851 N/A LEU 198.A N GLN 194.A O no hydrogen 3.073 N/A HIS 199.A N ILE 195.A O no hydrogen 3.233 N/A HIS 199.A ND1 ILE 195.A O no hydrogen 3.090 N/A ALA 200.A N SER 196.A O no hydrogen 3.008 N/A ILE 201.A N LYS 197.A O no hydrogen 3.077 N/A ILE 202.A N HIS 199.A O no hydrogen 3.258 N/A ASP 203.A N HIS 199.A O no hydrogen 2.863 N/A ASN 205.A N ASP 203.A OD1 no hydrogen 3.363 N/A HIS 206.A N ASP 203.A O no hydrogen 3.326 N/A HIS 206.A ND1 HIS 206.A O no hydrogen 2.842 N/A GLU 207.A N ASN 205.A O no hydrogen 2.819 N/A LEU 218.A N GLU 215.A O no hydrogen 3.218 N/A GLN 219.A N GLU 215.A O no hydrogen 3.351 N/A ASP 220.A N LYS 216.A O no hydrogen 3.205 N/A VAL 221.A N ASP 217.A O no hydrogen 3.232 N/A LEU 222.A N LEU 218.A O no hydrogen 3.162 N/A LYS 223.A N GLN 219.A O no hydrogen 3.099 N/A CYS 224.A N ASP 220.A O no hydrogen 2.921 N/A CYS 224.A SG ASP 220.A O no hydrogen 3.320 N/A CYS 224.A SG ASP 220.A OD2 no hydrogen 3.788 N/A CYS 225.A N VAL 221.A O no hydrogen 2.912 N/A CYS 225.A SG VAL 221.A O no hydrogen 3.306 N/A LEU 226.A N LEU 222.A O no hydrogen 3.096 N/A ARG 228.A NE ILE 201.A O no hydrogen 2.810 N/A ARG 228.A NH1 HIS 206.A O no hydrogen 3.017 N/A ARG 228.A NH2 ALA 200.A O no hydrogen 2.803 N/A ARG 228.A NH2 HIS 206.A O no hydrogen 2.771 N/A LYS 231.A N ASP 229.A OD1 no hydrogen 3.417 N/A GLN 232.A N ASP 229.A O no hydrogen 2.914 N/A ARG 233.A N ASP 229.A O no hydrogen 2.993 N/A ARG 233.A N PRO 230.A O no hydrogen 3.245 N/A ARG 233.A NE LYS 227.A O no hydrogen 2.767 N/A ARG 233.A NH1 GLU 160.A OE1 no hydrogen 3.117 N/A ARG 233.A NH1 GLU 160.A OE2 no hydrogen 2.726 N/A ARG 233.A NH1 LYS 168.A O no hydrogen 2.807 N/A ARG 233.A NH2 GLU 160.A OE1 no hydrogen 2.828 N/A ARG 233.A NH2 LYS 227.A O no hydrogen 3.059 N/A ILE 234.A N CYS 224.A O no hydrogen 3.312 N/A SER 235.A OG GLU 238.A OE1 no hydrogen 3.291 N/A LEU 239.A N SER 235.A O no hydrogen 2.951 N/A LEU 240.A N ILE 236.A O no hydrogen 2.883 N/A ALA 241.A N GLU 238.A O no hydrogen 2.949 N/A HIS 242.A N LEU 239.A O no hydrogen 3.113 N/A HIS 242.A NE2 ASP 220.A OD2 no hydrogen 2.758 N/A TYR 244.A N HIS 242.A ND1 no hydrogen 2.949 N/A VAL 245.A N HIS 242.A O no hydrogen 3.066 N/A GLN 246.A N HIS 242.A O no hydrogen 3.101 N/A GLN 246.A NE2 LEU 240.A O no hydrogen 2.762 N/A ILE 247.A N PRO 243.A O no hydrogen 2.760 N/A