Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4f9c_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): GLU 5.A N LYS 1.A O no hydrogen 3.286 N/A LYS 6.A N LYS 2.A O no hydrogen 3.018 N/A LEU 7.A N ASP 3.A O no hydrogen 3.011 N/A TYR 8.A N ILE 4.A O no hydrogen 3.137 N/A TYR 8.A OH PHE 18.A O no hydrogen 2.892 N/A GLU 9.A N GLU 5.A O no hydrogen 3.132 N/A ALA 10.A N LYS 6.A O no hydrogen 2.924 N/A VAL 11.A N LEU 7.A O no hydrogen 2.927 N/A GLN 13.A N GLN 13.A OE1 no hydrogen 2.720 N/A GLN 13.A NE2 ARG 85.A O no hydrogen 2.969 N/A LEU 14.A N VAL 11.A O no hydrogen 2.967 N/A SER 15.A N PRO 12.A O no hydrogen 3.011 N/A SER 15.A OG PRO 12.A O no hydrogen 2.714 N/A ASN 16.A N GLN 13.A O no hydrogen 3.040 N/A VAL 17.A N LEU 14.A O no hydrogen 3.097 N/A PHE 18.A N LEU 14.A O no hydrogen 2.829 N/A LYS 19.A N THR 36.A O no hydrogen 2.865 N/A ILE 20.A N TYR 8.A OH no hydrogen 2.927 N/A GLU 21.A N LEU 34.A O no hydrogen 2.745 N/A ASP 22.A N LEU 34.A O no hydrogen 3.361 N/A LYS 23.A N ASP 22.A OD1 no hydrogen 2.876 N/A LYS 23.A NZ ASP 3.A OD2 no hydrogen 2.801 N/A LYS 23.A NZ GLU 26.A OE1 no hydrogen 2.591 N/A ILE 24.A N VAL 32.A O no hydrogen 2.778 N/A GLY 25.A N VAL 32.A O no hydrogen 3.166 N/A GLY 27.A N SER 30.A O no hydrogen 2.889 N/A SER 31.A N HIS 51.A O no hydrogen 3.035 N/A SER 31.A OG GLU 26.A OE2 no hydrogen 3.160 N/A VAL 32.A N GLY 25.A O no hydrogen 2.952 N/A TYR 33.A N LEU 49.A O no hydrogen 2.764 N/A LEU 34.A N ASP 22.A O no hydrogen 2.667 N/A ALA 35.A N ILE 47.A O no hydrogen 2.838 N/A THR 36.A N LYS 19.A O no hydrogen 2.848 N/A THR 36.A OG1 GLU 21.A OE2 no hydrogen 2.594 N/A ALA 37.A N GLU 45.A O no hydrogen 2.960 N/A GLN 38.A NE2 LEU 39.A O no hydrogen 2.882 N/A GLN 38.A NE2 GLY 42.A O no hydrogen 2.424 N/A LEU 39.A N PRO 43.A O no hydrogen 2.787 N/A GLY 42.A N LEU 39.A O no hydrogen 3.083 N/A GLU 45.A N ALA 37.A O no hydrogen 2.768 N/A ILE 47.A N ALA 35.A O no hydrogen 2.712 N/A ALA 48.A N MET 94.A O no hydrogen 2.841 N/A LEU 49.A N TYR 33.A O no hydrogen 2.827 N/A LYS 50.A N ILE 92.A O no hydrogen 2.805 N/A LYS 50.A NZ GLU 64.A OE2 no hydrogen 2.697 N/A LYS 50.A NZ ASP 156.A OD1 no hydrogen 2.725 N/A HIS 51.A N SER 31.A O no hydrogen 2.883 N/A HIS 51.A NE2 HIS 89.A ND1 no hydrogen 2.738 N/A LEU 52.A N VAL 90.A O no hydrogen 3.055 N/A ILE 53.A N PHE 29.A O no hydrogen 2.863 N/A SER 56.A N ILE 53.A O no hydrogen 2.986 N/A SER 56.A OG ILE 53.A O no hydrogen 2.742 N/A ILE 59.A N HIS 57.A ND1 no hydrogen 3.097 N/A ARG 60.A NH1 ALA 160.A O no hydrogen 2.838 N/A ILE 61.A N HIS 57.A O no hydrogen 2.997 N/A ALA 62.A N PRO 58.A O no hydrogen 2.751 N/A ALA 63.A N ILE 59.A O no hydrogen 2.745 N/A GLU 64.A N ARG 60.A O no hydrogen 3.108 N/A LEU 65.A N ILE 61.A O no hydrogen 3.135 N/A GLN 66.A N ALA 62.A O no hydrogen 2.832 N/A CYS 67.A N ALA 63.A O no hydrogen 2.936 N/A CYS 67.A SG ALA 63.A O no hydrogen 3.444 N/A LEU 68.A N GLU 64.A O no hydrogen 3.079 N/A THR 69.A N LEU 65.A O no hydrogen 2.808 N/A THR 69.A OG1 LEU 65.A O no hydrogen 2.722 N/A VAL 70.A N GLN 66.A O no hydrogen 2.816 N/A ALA 71.A N CYS 67.A O no hydrogen 2.889 N/A GLY 72.A N CYS 67.A O no hydrogen 3.220 N/A GLY 73.A N VAL 77.A O no hydrogen 2.742 N/A GLN 74.A N VAL 77.A O no hydrogen 3.248 N/A ASN 76.A ND2 ASN 120.A O no hydrogen 3.005 N/A ASN 76.A ND2 ASN 120.A OD1 no hydrogen 2.980 N/A VAL 77.A N GLN 74.A O no hydrogen 3.026 N/A MET 78.A N LEU 154.A O no hydrogen 3.042 N/A LYS 81.A N ALA 93.A O no hydrogen 2.859 N/A TYR 82.A N ALA 93.A O no hydrogen 3.323 N/A CYS 83.A SG VAL 91.A O no hydrogen 3.828 N/A PHE 84.A N VAL 91.A O no hydrogen 2.776 N/A ARG 85.A NH1 ASN 87.A O no hydrogen 2.908 N/A LYS 86.A N HIS 89.A O no hydrogen 3.093 N/A ASP 88.A N ASP 88.A OD1 no hydrogen 2.576 N/A HIS 89.A N LYS 86.A O no hydrogen 3.014 N/A HIS 89.A ND1 HIS 51.A NE2 no hydrogen 2.738 N/A VAL 91.A N PHE 84.A O no hydrogen 2.814 N/A ILE 92.A N LYS 50.A O no hydrogen 2.810 N/A ALA 93.A N TYR 82.A O no hydrogen 2.791 N/A MET 94.A N ALA 48.A O no hydrogen 2.854 N/A TYR 96.A N LYS 46.A O no hydrogen 3.357 N/A HIS 99.A ND1 LEU 97.A O no hydrogen 2.917 N/A GLU 100.A N TYR 145.A O no hydrogen 2.868 N/A ASP 104.A N SER 101.A OG no hydrogen 3.251 N/A ILE 105.A N SER 101.A O no hydrogen 3.357 N/A LEU 106.A N PHE 102.A O no hydrogen 2.944 N/A ASN 107.A ND2 GLY 212.A O no hydrogen 2.911 N/A SER 108.A N ILE 105.A O no hydrogen 2.902 N/A SER 108.A OG ILE 105.A O no hydrogen 3.258 N/A SER 110.A N GLU 113.A OE1 no hydrogen 3.120 N/A GLN 112.A NE2 GLU 116.A OE2 no hydrogen 3.380 N/A GLU 113.A N SER 110.A OG no hydrogen 3.289 N/A VAL 114.A N SER 110.A O no hydrogen 3.146 N/A ARG 115.A N PHE 111.A O no hydrogen 3.052 N/A ARG 115.A NE PHE 302.A O no hydrogen 3.227 N/A ARG 115.A NH1 PHE 302.A O no hydrogen 2.698 N/A ARG 115.A NH1 LYS 304.A O no hydrogen 2.788 N/A ARG 115.A NH2 GLN 112.A OE1 no hydrogen 3.096 N/A GLU 116.A N GLN 112.A O no hydrogen 2.931 N/A TYR 117.A N GLU 113.A O no hydrogen 3.000 N/A MET 118.A N VAL 114.A O no hydrogen 3.094 N/A LEU 119.A N ARG 115.A O no hydrogen 2.931 N/A ASN 120.A N GLU 116.A O no hydrogen 2.953 N/A ASN 120.A ND2 GLU 116.A O no hydrogen 2.729 N/A LEU 121.A N TYR 117.A O no hydrogen 2.889 N/A PHE 122.A N MET 118.A O no hydrogen 2.986 N/A LYS 123.A N LEU 119.A O no hydrogen 3.109 N/A ALA 124.A N ASN 120.A O no hydrogen 3.290 N/A LEU 125.A N LEU 121.A O no hydrogen 2.956 N/A LYS 126.A N PHE 122.A O no hydrogen 2.781 N/A ARG 127.A N LYS 123.A O no hydrogen 3.166 N/A ARG 127.A NE ALA 71.A O no hydrogen 2.838 N/A ARG 127.A NH2 ALA 71.A O no hydrogen 3.474 N/A ILE 128.A N ALA 124.A O no hydrogen 3.128 N/A HIS 129.A N LEU 125.A O no hydrogen 2.888 N/A HIS 129.A NE2 ASP 198.A OD2 no hydrogen 2.797 N/A GLN 130.A N LYS 126.A O no hydrogen 2.925 N/A PHE 131.A N ILE 128.A O no hydrogen 3.066 N/A GLY 132.A N HIS 129.A O no hydrogen 2.971 N/A ILE 133.A N ILE 128.A O no hydrogen 3.100 N/A VAL 134.A N GLN 161.A O no hydrogen 2.780 N/A HIS 135.A N ASP 198.A OD2 no hydrogen 2.863 N/A HIS 135.A NE2 VAL 155.A O no hydrogen 2.870 N/A ARG 136.A N ASP 198.A OD1 no hydrogen 2.848 N/A ARG 136.A NH1 GLN 193.A OE1 no hydrogen 2.676 N/A ARG 136.A NH2 GLN 193.A OE1 no hydrogen 2.846 N/A ASP 137.A N HIS 135.A ND1 no hydrogen 2.979 N/A LYS 139.A NZ THR 178.A OG1 no hydrogen 2.574 N/A ASN 142.A N LYS 139.A O no hydrogen 2.970 N/A ASN 142.A ND2 ASP 137.A O no hydrogen 2.854 N/A ASN 142.A ND2 ASP 137.A OD2 no hydrogen 3.439 N/A PHE 143.A N PRO 140.A O no hydrogen 2.955 N/A LEU 144.A N ALA 153.A O no hydrogen 2.779 N/A ASN 146.A N LYS 151.A O no hydrogen 2.807 N/A ASN 146.A ND2 GLU 98.A O no hydrogen 2.807 N/A ARG 147.A N GLU 100.A OE2 no hydrogen 2.883 N/A ARG 147.A NE GLU 113.A OE2 no hydrogen 3.195 N/A ARG 147.A NH1 SER 108.A OG no hydrogen 2.911 N/A ARG 147.A NH2 SER 108.A O no hydrogen 2.785 N/A ARG 147.A NH2 GLU 113.A OE1 no hydrogen 2.795 N/A LEU 149.A N ASN 146.A OD1 no hydrogen 2.748 N/A LYS 150.A N ARG 147.A O no hydrogen 3.293 N/A LYS 150.A NZ GLU 113.A OE2 no hydrogen 2.669 N/A LYS 150.A NZ TYR 145.A OH no hydrogen 3.487 N/A LYS 150.A NZ ARG 147.A O no hydrogen 2.923 N/A LYS 151.A N ASN 146.A O no hydrogen 3.122 N/A ALA 153.A N LEU 144.A O no hydrogen 3.052 N/A LEU 154.A N ASN 76.A O no hydrogen 2.638 N/A VAL 155.A N ASN 142.A O no hydrogen 2.867 N/A GLY 158.A N ASP 156.A OD1 no hydrogen 2.989 N/A ALA 160.A N PHE 157.A O no hydrogen 3.338 N/A GLN 161.A N VAL 134.A O no hydrogen 2.942 N/A THR 163.A N GLY 132.A O no hydrogen 2.932 N/A THR 163.A OG1 GLY 132.A O no hydrogen 3.563 N/A THR 163.A OG1 ASP 165.A OD1 no hydrogen 3.181 N/A THR 166.A N THR 163.A O no hydrogen 3.143 N/A THR 166.A OG1 PHE 131.A O no hydrogen 3.376 N/A THR 166.A OG1 GLY 132.A O no hydrogen 3.233 N/A LYS 167.A N PHE 131.A O no hydrogen 2.890 N/A LYS 167.A NZ GLN 130.A O no hydrogen 3.201 N/A ILE 168.A N THR 166.A OG1 no hydrogen 3.083 N/A LEU 170.A N GLN 66.A OE1 no hydrogen 2.994 N/A LEU 171.A N ILE 168.A O no hydrogen 2.924 N/A LYS 172.A N GLU 169.A O no hydrogen 3.196 N/A LYS 172.A NZ GLU 169.A OE1 no hydrogen 3.066 N/A PHE 173.A N LEU 170.A O no hydrogen 3.023 N/A VAL 174.A N LEU 171.A O no hydrogen 3.195 N/A ARG 175.A NE GLY 158.A O no hydrogen 3.089 N/A ARG 175.A NH2 GLY 158.A O no hydrogen 2.781 N/A THR 178.A N ASP 137.A OD1 no hydrogen 3.223 N/A PHE 181.A N THR 178.A O no hydrogen 3.012 N/A ARG 182.A N PRO 179.A O no hydrogen 3.142 N/A ARG 182.A NE ASP 222.A OD1 no hydrogen 3.129 N/A ARG 182.A NH2 ASP 222.A OD2 no hydrogen 2.912 N/A GLU 185.A N GLU 185.A OE1 no hydrogen 2.766 N/A VAL 186.A N ALA 183.A O no hydrogen 2.907 N/A LEU 187.A N ALA 183.A O no hydrogen 2.847 N/A THR 188.A N PRO 184.A O no hydrogen 3.014 N/A THR 188.A OG1 PRO 184.A O no hydrogen 2.834 N/A LYS 189.A N VAL 186.A O no hydrogen 3.002 N/A CYS 190.A N GLU 185.A O no hydrogen 2.780 N/A CYS 190.A SG ASN 192.A O no hydrogen 3.337 N/A CYS 190.A SG PHE 245.A O no hydrogen 3.879 N/A GLN 193.A NE2 CYS 190.A O no hydrogen 2.703 N/A ALA 196.A N THR 194.A OG1 no hydrogen 3.133 N/A ILE 197.A N THR 194.A O no hydrogen 3.096 N/A ASP 198.A N THR 195.A O no hydrogen 2.974 N/A TRP 200.A N ALA 196.A O no hydrogen 3.128 N/A SER 201.A N ILE 197.A O no hydrogen 3.273 N/A SER 201.A OG PHE 181.A O no hydrogen 2.602 N/A SER 201.A OG ILE 197.A O no hydrogen 3.263 N/A ALA 202.A N ASP 198.A O no hydrogen 2.960 N/A GLY 203.A N MET 199.A O no hydrogen 3.007 N/A VAL 204.A N TRP 200.A O no hydrogen 2.954 N/A ILE 205.A N SER 201.A O no hydrogen 3.025 N/A PHE 206.A N ALA 202.A O no hydrogen 2.908 N/A LEU 207.A N GLY 203.A O no hydrogen 2.736 N/A SER 208.A N VAL 204.A O no hydrogen 3.007 N/A SER 208.A OG ARG 213.A O no hydrogen 2.759 N/A LEU 209.A N ILE 205.A O no hydrogen 3.020 N/A LEU 210.A N PHE 206.A O no hydrogen 2.929 N/A SER 211.A N LEU 207.A O no hydrogen 3.037 N/A SER 211.A OG LEU 207.A O no hydrogen 2.809 N/A GLY 212.A N SER 208.A O no hydrogen 2.870 N/A ARG 213.A N SER 211.A OG no hydrogen 3.336 N/A ARG 213.A NE LEU 267.A O no hydrogen 2.860 N/A ARG 213.A NH2 LEU 267.A O no hydrogen 2.955 N/A THR 224.A N ASP 221.A OD2 no hydrogen 3.018 N/A THR 224.A OG1 ASP 221.A OD1 no hydrogen 3.473 N/A THR 224.A OG1 ASP 221.A OD2 no hydrogen 2.630 N/A ALA 225.A N ASP 221.A O no hydrogen 3.292 N/A LEU 226.A N ASP 222.A O no hydrogen 3.038 N/A ALA 227.A N LEU 223.A O no hydrogen 2.873 N/A GLN 228.A N THR 224.A O no hydrogen 2.937 N/A GLN 228.A NE2 LYS 218.A O no hydrogen 2.896 N/A ILE 229.A N ALA 225.A O no hydrogen 2.735 N/A MET 230.A N LEU 226.A O no hydrogen 2.878 N/A THR 231.A N ALA 227.A O no hydrogen 3.289 N/A THR 231.A N GLN 228.A O no hydrogen 3.130 N/A THR 231.A OG1 GLN 228.A O no hydrogen 2.953 N/A ILE 232.A N GLN 228.A O no hydrogen 3.353 N/A ILE 232.A N ILE 229.A O no hydrogen 3.038 N/A ARG 233.A N ILE 229.A O no hydrogen 2.803 N/A ARG 233.A NE LEU 284.A O no hydrogen 2.979 N/A ARG 233.A NH1 ASP 281.A OD1 no hydrogen 3.170 N/A ARG 233.A NH2 ASP 281.A OD1 no hydrogen 2.864 N/A ARG 233.A NH2 LEU 284.A O no hydrogen 2.985 N/A GLY 234.A N MET 230.A O no hydrogen 2.690 N/A SER 235.A N VAL 255.A O no hydrogen 3.021 N/A SER 235.A OG VAL 255.A O no hydrogen 3.367 N/A GLU 237.A N GLU 237.A OE1 no hydrogen 2.662 N/A THR 238.A N GLY 234.A O no hydrogen 3.001 N/A THR 238.A OG1 GLY 234.A O no hydrogen 2.804 N/A ILE 239.A N SER 235.A O no hydrogen 2.835 N/A GLN 240.A N ARG 236.A O no hydrogen 2.917 N/A ALA 241.A N GLU 237.A O no hydrogen 2.979 N/A ALA 242.A N THR 238.A O no hydrogen 2.885 N/A LYS 243.A N ILE 239.A O no hydrogen 3.307 N/A THR 244.A N ALA 241.A O no hydrogen 3.078 N/A THR 244.A OG1 ALA 241.A O no hydrogen 2.610 N/A PHE 245.A N ALA 242.A O no hydrogen 3.031 N/A GLY 246.A N LYS 243.A O no hydrogen 3.015 N/A LYS 247.A N ALA 242.A O no hydrogen 3.006 N/A LYS 247.A NZ THR 188.A O no hydrogen 3.142 N/A LYS 247.A NZ LYS 189.A O no hydrogen 3.119 N/A CYS 251.A SG LYS 253.A O no hydrogen 3.339 N/A VAL 255.A N SER 235.A OG no hydrogen 3.041 N/A GLN 258.A N ILE 232.A O no hydrogen 2.829 N/A ARG 261.A NH1 GLU 265.A OE1 no hydrogen 3.073 N/A ARG 261.A NH1 VAL 272.A O no hydrogen 3.244 N/A ARG 261.A NH2 VAL 272.A O no hydrogen 2.879 N/A ARG 261.A NH2 ASP 274.A OD1 no hydrogen 2.717 N/A LYS 262.A N ASP 259.A OD2 no hydrogen 2.910 N/A LEU 263.A N ASP 259.A O no hydrogen 2.989 N/A CYS 264.A N LEU 260.A O no hydrogen 3.000 N/A CYS 264.A SG LEU 260.A O no hydrogen 3.317 N/A GLU 265.A N ARG 261.A O no hydrogen 2.928 N/A ARG 266.A N LYS 262.A O no hydrogen 2.918 N/A LEU 267.A N LEU 263.A O no hydrogen 2.996 N/A ARG 268.A N CYS 264.A O no hydrogen 2.895 N/A ARG 268.A N GLU 265.A O no hydrogen 3.298 N/A ARG 268.A NE LEU 210.A O no hydrogen 2.761 N/A ARG 268.A NH2 LEU 210.A O no hydrogen 2.923 N/A ARG 268.A NH2 TYR 277.A OH no hydrogen 2.620 N/A TRP 269.A NE1 LEU 109.A O no hydrogen 2.737 N/A GLU 275.A N GLU 275.A OE1 no hydrogen 2.745 N/A ALA 276.A N PRO 273.A O no hydrogen 3.119 N/A ASP 278.A N ASP 274.A O no hydrogen 2.842 N/A LEU 279.A N GLU 275.A O no hydrogen 2.924 N/A LEU 280.A N ALA 276.A O no hydrogen 3.009 N/A ASP 281.A N TYR 277.A O no hydrogen 2.941 N/A LYS 282.A N ASP 278.A O no hydrogen 3.189 N/A LYS 282.A NZ ASP 278.A OD1 no hydrogen 3.211 N/A LYS 282.A NZ ASP 278.A OD2 no hydrogen 2.686 N/A LEU 283.A N LEU 279.A O no hydrogen 2.948 N/A LEU 284.A N LEU 280.A O no hydrogen 2.921 N/A ASP 285.A N LYS 282.A O no hydrogen 3.376 N/A ASN 287.A N ASP 285.A OD1 no hydrogen 2.866 N/A ALA 289.A N ASN 287.A OD1 no hydrogen 2.858 N/A SER 290.A OG ASP 285.A OD2 no hydrogen 2.435 N/A SER 290.A OG ASN 287.A O no hydrogen 3.402 N/A ARG 291.A N ASN 287.A O no hydrogen 3.044 N/A ARG 291.A NE ASP 285.A O no hydrogen 2.819 N/A ARG 291.A NH1 GLU 185.A OE1 no hydrogen 3.553 N/A ARG 291.A NH1 GLU 185.A OE2 no hydrogen 2.780 N/A ARG 291.A NH1 ALA 196.A O no hydrogen 2.929 N/A ARG 291.A NH2 GLU 185.A OE1 no hydrogen 3.068 N/A ARG 291.A NH2 ASP 285.A O no hydrogen 2.876 N/A ILE 292.A N LYS 282.A O no hydrogen 3.482 N/A THR 293.A N GLU 296.A OE1 no hydrogen 3.093 N/A GLU 296.A N THR 293.A OG1 no hydrogen 3.100 N/A ALA 297.A N THR 293.A O no hydrogen 2.780 N/A LEU 298.A N ALA 294.A O no hydrogen 3.117 N/A LEU 299.A N GLU 296.A O no hydrogen 3.028 N/A HIS 300.A N ALA 297.A O no hydrogen 3.099 N/A HIS 300.A NE2 ASP 278.A OD2 no hydrogen 2.769 N/A PHE 302.A N HIS 300.A ND1 no hydrogen 2.936 N/A PHE 303.A N HIS 300.A O no hydrogen 2.967 N/A LYS 304.A N PRO 301.A O no hydrogen 3.201 N/A