Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4fzd_B.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): GLU 5.A N ASP 3.A OD1 no hydrogen 3.265 N/A GLU 6.A N ASP 3.A O no hydrogen 3.127 N/A LEU 7.A N ASP 3.A O no hydrogen 3.109 N/A PHE 8.A N PRO 4.A O no hydrogen 2.719 N/A THR 9.A N ILE 26.A O no hydrogen 3.033 N/A THR 9.A OG1 ASN 28.A OD1 no hydrogen 2.516 N/A LEU 11.A N LYS 24.A O no hydrogen 2.665 N/A ARG 13.A NE GLY 15.A O no hydrogen 2.743 N/A ARG 13.A NH2 GLY 15.A O no hydrogen 3.385 N/A ILE 14.A N VAL 22.A O no hydrogen 2.866 N/A LYS 16.A NZ GLU 12.A OE1 no hydrogen 3.012 N/A LYS 16.A NZ GLU 12.A OE2 no hydrogen 3.314 N/A PHE 23.A N ILE 36.A O no hydrogen 2.776 N/A LYS 24.A N GLU 12.A O no hydrogen 2.909 N/A GLY 25.A N VAL 34.A O no hydrogen 2.690 N/A ILE 26.A N THR 9.A O no hydrogen 3.049 N/A ASP 27.A N GLN 32.A O no hydrogen 2.867 N/A ASN 28.A N LEU 7.A O no hydrogen 2.939 N/A ASN 28.A ND2 GLU 6.A O no hydrogen 2.531 N/A THR 30.A N ASP 27.A OD1 no hydrogen 3.180 N/A GLN 31.A N ASP 27.A O no hydrogen 2.491 N/A GLN 32.A N THR 30.A OG1 no hydrogen 3.241 N/A VAL 34.A N GLY 25.A O no hydrogen 2.728 N/A ALA 35.A N MET 83.A O no hydrogen 2.775 N/A ILE 36.A N PHE 23.A O no hydrogen 2.607 N/A LYS 37.A N ILE 81.A O no hydrogen 2.800 N/A ILE 38.A N GLU 21.A O no hydrogen 2.820 N/A ILE 39.A N LEU 79.A O no hydrogen 3.072 N/A GLU 42.A N ASP 40.A O no hydrogen 2.738 N/A GLU 43.A N ASP 40.A OD1 no hydrogen 3.527 N/A GLU 45.A N LEU 41.A O no hydrogen 3.063 N/A ASP 46.A N ALA 44.A O no hydrogen 2.294 N/A ASP 50.A N GLU 47.A O no hydrogen 2.925 N/A ILE 51.A N GLU 47.A O no hydrogen 3.349 N/A GLN 52.A N ILE 48.A O no hydrogen 2.773 N/A GLN 53.A N GLU 49.A O no hydrogen 2.789 N/A GLU 54.A N ASP 50.A O no hydrogen 2.747 N/A ILE 55.A N ILE 51.A O no hydrogen 3.087 N/A ILE 55.A N GLN 52.A O no hydrogen 2.970 N/A THR 56.A N GLN 52.A O no hydrogen 2.739 N/A THR 56.A OG1 GLN 52.A O no hydrogen 3.236 N/A THR 56.A OG1 GLN 53.A O no hydrogen 2.841 N/A VAL 57.A N GLN 53.A O no hydrogen 2.880 N/A LEU 58.A N GLU 54.A O no hydrogen 3.371 N/A SER 59.A N ILE 55.A O no hydrogen 2.832 N/A SER 59.A OG ILE 55.A O no hydrogen 3.162 N/A SER 59.A OG THR 56.A O no hydrogen 2.585 N/A GLN 60.A N VAL 57.A O no hydrogen 3.213 N/A CYS 61.A N LEU 58.A O no hydrogen 3.124 N/A CYS 61.A SG VAL 57.A O no hydrogen 3.594 N/A CYS 61.A SG LEU 58.A O no hydrogen 3.663 N/A ASP 62.A N TYR 118.A OH no hydrogen 2.784 N/A TYR 65.A N SER 63.A OG no hydrogen 2.836 N/A VAL 66.A N SER 63.A O no hydrogen 3.445 N/A THR 67.A N LEU 144.A O no hydrogen 3.004 N/A LYS 68.A N GLU 84.A OE2 no hydrogen 2.814 N/A TYR 70.A N ILE 82.A O no hydrogen 2.780 N/A SER 72.A OG TYR 69.A OH no hydrogen 3.263 N/A TYR 73.A N TRP 80.A O no hydrogen 2.812 N/A LYS 75.A N LYS 78.A O no hydrogen 2.848 N/A LYS 78.A N LYS 75.A O no hydrogen 2.794 N/A LYS 78.A NZ ASP 40.A OD2 no hydrogen 3.042 N/A LEU 79.A N ILE 39.A O no hydrogen 2.950 N/A TRP 80.A N TYR 73.A O no hydrogen 2.631 N/A ILE 81.A N LYS 37.A O no hydrogen 2.680 N/A ILE 82.A N GLY 71.A O no hydrogen 2.665 N/A MET 83.A N ALA 35.A O no hydrogen 2.827 N/A GLU 84.A N LYS 68.A O no hydrogen 2.930 N/A GLY 89.A N LEU 86.A O no hydrogen 3.324 N/A SER 90.A N ASP 93.A OD2 no hydrogen 3.467 N/A ALA 91.A N VAL 134.A O no hydrogen 2.839 N/A LEU 92.A N ALA 131.A O no hydrogen 3.383 N/A ASP 93.A N SER 90.A OG no hydrogen 2.990 N/A LEU 94.A N SER 90.A O no hydrogen 2.801 N/A LEU 95.A N ALA 91.A O no hydrogen 2.972 N/A ARG 96.A N ASP 93.A O no hydrogen 3.170 N/A ALA 97.A N LEU 94.A O no hydrogen 3.243 N/A GLY 98.A N LEU 95.A O no hydrogen 3.222 N/A ASP 101.A N GLN 104.A OE1 no hydrogen 2.799 N/A ILE 105.A N ASP 101.A O no hydrogen 2.915 N/A ALA 106.A N GLU 102.A O no hydrogen 2.939 N/A THR 107.A N PHE 103.A O no hydrogen 2.893 N/A THR 107.A OG1 PHE 103.A O no hydrogen 2.684 N/A MET 108.A N GLN 104.A O no hydrogen 3.116 N/A LEU 109.A N ILE 105.A O no hydrogen 3.056 N/A LYS 110.A N ALA 106.A O no hydrogen 2.991 N/A GLU 111.A N THR 107.A O no hydrogen 3.310 N/A ILE 112.A N MET 108.A O no hydrogen 2.940 N/A LEU 113.A N LEU 109.A O no hydrogen 2.754 N/A LYS 114.A N LYS 110.A O no hydrogen 3.109 N/A LYS 114.A NZ GLU 111.A OE1 no hydrogen 3.446 N/A GLY 115.A N GLU 111.A O no hydrogen 2.988 N/A LEU 116.A N ILE 112.A O no hydrogen 2.791 N/A ASP 117.A N LEU 113.A O no hydrogen 2.777 N/A TYR 118.A N LYS 114.A O no hydrogen 2.865 N/A LEU 119.A N GLY 115.A O no hydrogen 2.802 N/A HIS 120.A N LEU 116.A O no hydrogen 2.767 N/A HIS 120.A NE2 ASP 179.A OD2 no hydrogen 3.280 N/A SER 121.A N ASP 117.A O no hydrogen 3.089 N/A SER 121.A OG ASP 117.A O no hydrogen 2.494 N/A LYS 124.A N LEU 119.A O no hydrogen 2.969 N/A LYS 124.A NZ GLN 60.A OE1 no hydrogen 3.377 N/A LYS 124.A NZ GLU 122.A OE2 no hydrogen 3.175 N/A ILE 125.A N ALA 150.A O no hydrogen 2.948 N/A HIS 126.A N ASP 179.A OD2 no hydrogen 2.526 N/A HIS 126.A NE2 ALA 145.A O no hydrogen 2.782 N/A ARG 127.A N ASP 179.A OD1 no hydrogen 3.268 N/A ASP 128.A N HIS 126.A ND1 no hydrogen 3.054 N/A ALA 131.A N GLU 189.A OE1 no hydrogen 2.793 N/A ASN 133.A N LYS 130.A O no hydrogen 2.633 N/A ASN 133.A ND2 ASP 128.A O no hydrogen 2.572 N/A ASN 133.A ND2 ASP 128.A OD2 no hydrogen 2.908 N/A VAL 134.A N ALA 131.A O no hydrogen 3.164 N/A LEU 135.A N LYS 143.A O no hydrogen 2.912 N/A LEU 136.A N GLY 89.A O no hydrogen 2.793 N/A SER 137.A N ASP 141.A O no hydrogen 2.946 N/A GLY 140.A N SER 137.A O no hydrogen 2.978 N/A ASP 141.A N SER 137.A OG no hydrogen 2.657 N/A LYS 143.A N LEU 135.A O no hydrogen 2.993 N/A LYS 143.A NZ SER 64.A O no hydrogen 3.009 N/A LYS 143.A NZ GLU 84.A OE1 no hydrogen 3.478 N/A LEU 144.A N TYR 65.A O no hydrogen 2.880 N/A ALA 145.A N ASN 133.A O no hydrogen 3.036 N/A VAL 149.A N ALA 146.A O no hydrogen 2.984 N/A ALA 150.A N ILE 125.A O no hydrogen 3.109 N/A GLN 152.A N LYS 123.A O no hydrogen 3.314 N/A THR 154.A N GLY 151.A O no hydrogen 3.243 N/A TRP 163.A NE1 GLU 189.A OE1 no hydrogen 2.935 N/A MET 164.A N PRO 161.A O no hydrogen 3.171 N/A GLU 167.A N GLU 167.A OE1 no hydrogen 2.752 N/A ILE 169.A N ALA 165.A O no hydrogen 3.166 N/A GLN 170.A N PRO 166.A O no hydrogen 3.215 N/A GLN 171.A N VAL 168.A O no hydrogen 2.916 N/A GLN 171.A NE2 ILE 169.A O no hydrogen 3.147 N/A SER 172.A N GLU 167.A O no hydrogen 2.950 N/A LYS 177.A NZ PRO 237.A O no hydrogen 3.305 N/A LYS 177.A NZ ARG 240.A O no hydrogen 2.625 N/A ALA 178.A N ASP 175.A O no hydrogen 2.944 N/A ASP 179.A N SER 176.A O no hydrogen 2.990 N/A ILE 180.A N SER 176.A O no hydrogen 3.367 N/A TRP 181.A N LYS 177.A O no hydrogen 3.119 N/A SER 182.A N ALA 178.A O no hydrogen 3.202 N/A SER 182.A OG TRP 163.A O no hydrogen 2.711 N/A SER 182.A OG ALA 178.A O no hydrogen 3.456 N/A LEU 183.A N ASP 179.A O no hydrogen 2.952 N/A GLY 184.A N ILE 180.A O no hydrogen 3.168 N/A ILE 185.A N TRP 181.A O no hydrogen 3.240 N/A THR 186.A N SER 182.A O no hydrogen 2.747 N/A THR 186.A OG1 SER 182.A O no hydrogen 3.056 N/A ALA 187.A N LEU 183.A O no hydrogen 2.768 N/A ILE 188.A N GLY 184.A O no hydrogen 3.132 N/A GLU 189.A N ILE 185.A O no hydrogen 2.700 N/A LEU 190.A N THR 186.A O no hydrogen 2.687 N/A ALA 191.A N ALA 187.A O no hydrogen 2.889 N/A LYS 192.A N ILE 188.A O no hydrogen 2.786 N/A LYS 192.A NZ VAL 218.A O no hydrogen 2.874 N/A GLY 193.A N GLU 189.A O no hydrogen 2.606 N/A SER 198.A N PRO 195.A O no hydrogen 3.265 N/A SER 198.A OG PRO 195.A O no hydrogen 2.639 N/A MET 200.A N ASN 197.A O no hydrogen 2.954 N/A VAL 205.A N HIS 201.A O no hydrogen 3.017 N/A LEU 206.A N PRO 202.A O no hydrogen 3.121 N/A PHE 207.A N ARG 204.A O no hydrogen 3.215 N/A LEU 208.A N ARG 204.A O no hydrogen 3.190 N/A LEU 208.A N VAL 205.A O no hydrogen 2.665 N/A ILE 209.A N VAL 205.A O no hydrogen 2.918 N/A ASN 212.A N LEU 208.A O no hydrogen 2.703 N/A PHE 221.A N GLY 219.A O no hydrogen 2.700 N/A THR 222.A N GLU 102.A OE2 no hydrogen 3.010 N/A THR 222.A OG1 GLU 102.A OE1 no hydrogen 3.109 N/A THR 222.A OG1 SER 224.A OG no hydrogen 3.212 N/A SER 224.A OG THR 222.A OG1 no hydrogen 3.212 N/A PHE 225.A N THR 222.A OG1 no hydrogen 3.318 N/A LYS 226.A N THR 222.A O no hydrogen 3.283 N/A LYS 226.A NZ GLY 219.A O no hydrogen 3.201 N/A GLU 227.A N LYS 223.A O no hydrogen 2.815 N/A PHE 228.A N SER 224.A O no hydrogen 2.757 N/A ILE 229.A N PHE 225.A O no hydrogen 3.060 N/A ASP 230.A N LYS 226.A O no hydrogen 2.828 N/A ALA 231.A N GLU 227.A O no hydrogen 2.989 N/A ALA 231.A N PHE 228.A O no hydrogen 2.912 N/A CYS 232.A N PHE 228.A O no hydrogen 3.199 N/A CYS 232.A SG PHE 228.A O no hydrogen 3.730 N/A LEU 233.A N ILE 229.A O no hydrogen 2.924 N/A LYS 235.A NZ PRO 210.A O no hydrogen 3.197 N/A LYS 235.A NZ ASN 212.A O no hydrogen 2.750 N/A ASP 236.A N ASN 234.A OD1 no hydrogen 3.098 N/A SER 238.A N ASP 236.A OD1 no hydrogen 3.428 N/A SER 238.A OG ASP 236.A OD1 no hydrogen 2.990 N/A PHE 239.A N ASP 236.A O no hydrogen 2.958 N/A ARG 240.A N PRO 237.A O no hydrogen 2.949 N/A ARG 240.A NE ASN 234.A O no hydrogen 2.665 N/A ARG 240.A NH1 GLU 167.A OE2 no hydrogen 2.784 N/A ARG 240.A NH1 LYS 177.A O no hydrogen 2.816 N/A ARG 240.A NH2 GLU 167.A OE1 no hydrogen 3.012 N/A ARG 240.A NH2 GLU 167.A OE2 no hydrogen 3.512 N/A ARG 240.A NH2 ASN 234.A O no hydrogen 2.880 N/A THR 242.A N GLU 245.A OE1 no hydrogen 2.843 N/A GLU 245.A N THR 242.A OG1 no hydrogen 2.948 N/A LEU 246.A N THR 242.A O no hydrogen 3.197 N/A LEU 247.A N ALA 243.A O no hydrogen 3.096 N/A LEU 247.A N LYS 244.A O no hydrogen 3.240 N/A LYS 248.A N GLU 245.A O no hydrogen 3.207 N/A PHE 251.A N HIS 249.A ND1 no hydrogen 2.982 N/A ILE 252.A N HIS 249.A O no hydrogen 2.832 N/A VAL 253.A N HIS 249.A O no hydrogen 3.052 N/A LYS 254.A N LYS 250.A O no hydrogen 2.897 N/A ASN 255.A N ILE 252.A O no hydrogen 3.085 N/A ASN 255.A ND2 PHE 251.A O no hydrogen 2.793 N/A SER 256.A N ILE 252.A O no hydrogen 2.755 N/A SER 256.A OG ILE 252.A O no hydrogen 2.559 N/A LYS 257.A N THR 107.A OG1 no hydrogen 3.228 N/A TYR 261.A N LYS 258.A O no hydrogen 3.241 N/A LEU 262.A N THR 259.A O no hydrogen 2.860 N/A THR 263.A N SER 260.A O no hydrogen 3.063 N/A THR 263.A OG1 SER 260.A O no hydrogen 3.124 N/A GLU 264.A N TYR 261.A O no hydrogen 3.144 N/A ILE 266.A N LEU 262.A O no hydrogen 3.414 N/A ASP 267.A N THR 263.A O no hydrogen 2.841 N/A ARG 268.A N GLU 264.A O no hydrogen 2.788 N/A ARG 268.A NH1 PRO 99.A O no hydrogen 3.195 N/A ARG 268.A NH2 GLY 98.A O no hydrogen 2.782 N/A ARG 268.A NH2 PRO 99.A O no hydrogen 3.508 N/A PHE 269.A N LEU 265.A O no hydrogen 2.968 N/A LYS 270.A N ILE 266.A O no hydrogen 2.901 N/A ARG 271.A N ASP 267.A O no hydrogen 2.890 N/A TRP 272.A N ARG 268.A O no hydrogen 2.911 N/A TRP 272.A N PHE 269.A O no hydrogen 2.749 N/A LYS 273.A N PHE 269.A O no hydrogen 2.970 N/A