Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4h8n_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ARG 8.A NH1 GLY 12.A O no hydrogen 2.613 N/A THR 9.A N LYS 13.A O no hydrogen 2.685 N/A THR 9.A OG1 SER 11.A OG no hydrogen 3.114 N/A THR 9.A OG1 LYS 13.A O no hydrogen 3.533 N/A THR 9.A OG1 GLU 77.A O no hydrogen 3.121 N/A SER 11.A N GLU 77.A O no hydrogen 2.991 N/A SER 11.A OG THR 9.A OG1 no hydrogen 3.114 N/A SER 11.A OG GLU 77.A O no hydrogen 3.076 N/A SER 11.A OG ASP 78.A OD1 no hydrogen 2.589 N/A GLY 12.A N THR 9.A O no hydrogen 2.817 N/A LYS 13.A N THR 9.A OG1 no hydrogen 2.930 N/A ILE 15.A N PHE 7.A O no hydrogen 3.255 N/A SER 16.A OG ILE 17.A O no hydrogen 2.911 N/A ALA 18.A N PRO 254.A O no hydrogen 3.004 N/A LEU 19.A N HIS 52.A O no hydrogen 2.819 N/A GLY 20.A N THR 256.A O no hydrogen 2.859 N/A THR 21.A N ASP 54.A O no hydrogen 3.017 N/A THR 21.A OG1 ASP 54.A O no hydrogen 2.732 N/A THR 21.A OG1 THR 61.A OG1 no hydrogen 3.234 N/A TRP 25.A N GLY 22.A O no hydrogen 2.977 N/A TRP 25.A NE1 THR 257.A OG1 no hydrogen 2.990 N/A LYS 26.A N THR 23.A O no hydrogen 3.224 N/A LYS 26.A NZ THR 23.A O no hydrogen 3.210 N/A GLN 27.A N TYR 59.A O no hydrogen 2.826 N/A GLN 27.A NE2 GLU 64.A OE2 no hydrogen 2.528 N/A GLN 29.A NE2 GLU 57.A O no hydrogen 3.044 N/A GLN 29.A NE2 ALA 58.A O no hydrogen 3.674 N/A ILE 31.A N ALA 28.A O no hydrogen 3.394 N/A SER 35.A N GLU 64.A OE2 no hydrogen 2.657 N/A LEU 38.A N SER 35.A OG no hydrogen 3.041 N/A VAL 39.A N SER 35.A O no hydrogen 3.005 N/A ASP 40.A N THR 36.A O no hydrogen 2.920 N/A ASN 41.A N GLU 37.A O no hydrogen 3.086 N/A ASN 41.A ND2 SER 258.A O no hydrogen 3.182 N/A ILE 42.A N LEU 38.A O no hydrogen 2.893 N/A LEU 43.A N VAL 39.A O no hydrogen 2.907 N/A LEU 44.A N ASP 40.A O no hydrogen 2.847 N/A GLY 45.A N ASN 41.A O no hydrogen 2.938 N/A LEU 46.A N ILE 42.A O no hydrogen 2.866 N/A LYS 47.A N LEU 43.A O no hydrogen 2.928 N/A LEU 48.A N LEU 44.A O no hydrogen 2.866 N/A GLY 49.A N GLY 45.A O no hydrogen 3.000 N/A GLY 49.A N LEU 46.A O no hydrogen 3.141 N/A PHE 50.A N GLY 45.A O no hydrogen 2.890 N/A ARG 51.A N SER 16.A OG no hydrogen 2.954 N/A ARG 51.A NH1 LEU 46.A O no hydrogen 2.417 N/A ARG 51.A NH1 PHE 50.A O no hydrogen 2.833 N/A HIS 52.A ND1 SER 16.A O no hydrogen 3.031 N/A HIS 52.A NE2 THR 82.A OG1 no hydrogen 2.866 N/A ILE 53.A N TRP 80.A O no hydrogen 2.935 N/A ASP 54.A N LEU 19.A O no hydrogen 2.955 N/A THR 55.A N THR 82.A O no hydrogen 2.845 N/A THR 55.A OG1 THR 61.A OG1 no hydrogen 2.852 N/A ALA 56.A N THR 55.A OG1 no hydrogen 2.653 N/A GLU 57.A N LYS 84.A O no hydrogen 3.029 N/A ALA 58.A N SER 86.A OG no hydrogen 2.880 N/A TYR 59.A N ALA 56.A O no hydrogen 3.055 N/A ASN 60.A N GLU 57.A O no hydrogen 3.157 N/A ASN 60.A ND2 ALA 28.A O no hydrogen 2.613 N/A ASN 60.A ND2 ILE 31.A O no hydrogen 2.862 N/A THR 61.A OG1 THR 21.A O no hydrogen 3.185 N/A THR 61.A OG1 THR 21.A OG1 no hydrogen 3.234 N/A THR 61.A OG1 THR 55.A OG1 no hydrogen 2.852 N/A GLN 62.A NE2 THR 83.A OG1 no hydrogen 2.624 N/A LYS 63.A NZ GLN 27.A OE1 no hydrogen 2.861 N/A LYS 63.A NZ ASP 33.A O no hydrogen 3.000 N/A LYS 63.A NZ ASN 60.A O no hydrogen 3.096 N/A LYS 63.A NZ GLU 64.A OE1 no hydrogen 2.262 N/A GLU 64.A N GLU 64.A OE1 no hydrogen 2.934 N/A VAL 65.A N THR 61.A O no hydrogen 2.964 N/A GLY 66.A N GLN 62.A O no hydrogen 2.699 N/A GLU 67.A N LYS 63.A O no hydrogen 2.900 N/A ALA 68.A N GLU 64.A O no hydrogen 2.979 N/A LEU 69.A N VAL 65.A O no hydrogen 2.922 N/A LYS 70.A N GLY 66.A O no hydrogen 2.999 N/A ARG 71.A N GLU 67.A O no hydrogen 3.027 N/A ARG 71.A NH1 GLU 67.A OE2 no hydrogen 2.806 N/A THR 72.A N ALA 68.A O no hydrogen 2.880 N/A VAL 74.A N THR 72.A OG1 no hydrogen 3.172 N/A ARG 76.A NH1 TYR 114.A O no hydrogen 2.789 N/A ARG 76.A NH1 ASP 116.A OD2 no hydrogen 2.932 N/A ARG 76.A NH2 ARG 76.A O no hydrogen 2.864 N/A ARG 76.A NH2 ILE 79.A O no hydrogen 2.991 N/A ARG 76.A NH2 ASP 116.A OD2 no hydrogen 3.178 N/A GLU 77.A N GLU 77.A OE1 no hydrogen 2.668 N/A ASP 78.A N PRO 75.A O no hydrogen 2.860 N/A ILE 79.A N ARG 76.A O no hydrogen 2.950 N/A TRP 80.A N ARG 51.A O no hydrogen 2.681 N/A TRP 80.A NE1 THR 82.A OG1 no hydrogen 2.985 N/A VAL 81.A N ASP 116.A OD2 no hydrogen 2.799 N/A THR 82.A N ILE 53.A O no hydrogen 2.881 N/A THR 82.A OG1 HIS 52.A NE2 no hydrogen 2.866 N/A THR 83.A N LEU 117.A O no hydrogen 2.945 N/A LYS 84.A N THR 83.A OG1 no hydrogen 2.720 N/A LYS 84.A NZ ASP 54.A OD1 no hydrogen 3.379 N/A LYS 84.A NZ ASP 54.A OD2 no hydrogen 2.577 N/A LYS 84.A NZ THR 55.A O no hydrogen 2.749 N/A LYS 84.A NZ TYR 59.A OH no hydrogen 3.038 N/A TYR 85.A N LEU 119.A O no hydrogen 2.869 N/A SER 86.A N GLU 57.A OE1 no hydrogen 3.406 N/A SER 86.A OG HIS 121.A ND1 no hydrogen 2.812 N/A TRP 89.A N ILE 92.A O no hydrogen 2.754 N/A ILE 92.A N TRP 89.A O no hydrogen 2.772 N/A ALA 94.A N GLN 129.A O no hydrogen 2.760 N/A SER 96.A OG GLU 57.A OE2 no hydrogen 2.682 N/A ASP 101.A N SER 98.A OG no hydrogen 2.949 N/A SER 102.A N SER 98.A O no hydrogen 3.019 N/A SER 102.A OG GLU 57.A OE1 no hydrogen 2.717 N/A ILE 103.A N PRO 99.A O no hydrogen 3.159 N/A ASP 104.A N SER 100.A O no hydrogen 3.227 N/A LYS 105.A N ASP 101.A O no hydrogen 2.830 N/A LYS 105.A NZ GLN 29.A OE1 no hydrogen 2.934 N/A LYS 105.A NZ GLU 57.A OE2 no hydrogen 2.842 N/A ALA 106.A N SER 102.A O no hydrogen 2.862 N/A LEU 107.A N ILE 103.A O no hydrogen 2.997 N/A ALA 108.A N ASP 104.A O no hydrogen 3.022 N/A GLN 109.A N LYS 105.A O no hydrogen 2.945 N/A LEU 110.A N ALA 106.A O no hydrogen 2.856 N/A GLY 111.A N ALA 108.A O no hydrogen 3.184 N/A VAL 112.A N LEU 107.A O no hydrogen 3.213 N/A VAL 115.A N LYS 150.A O no hydrogen 2.882 N/A ASP 116.A N VAL 81.A O no hydrogen 3.102 N/A LEU 117.A N VAL 81.A O no hydrogen 3.139 N/A PHE 118.A N GLU 153.A O no hydrogen 3.121 N/A LEU 119.A N THR 83.A O no hydrogen 2.828 N/A ILE 120.A N GLY 155.A O no hydrogen 2.987 N/A HIS 121.A N TYR 85.A O no hydrogen 2.943 N/A HIS 121.A ND1 SER 86.A OG no hydrogen 2.812 N/A PHE 124.A N SER 122.A OG no hydrogen 2.946 N/A THR 126.A N GLN 129.A OE1 no hydrogen 2.968 N/A GLU 128.A N THR 126.A OG1 no hydrogen 3.263 N/A GLN 129.A N THR 126.A OG1 no hydrogen 3.314 N/A GLN 129.A NE2 GLY 90.A O no hydrogen 3.455 N/A THR 130.A N THR 126.A O no hydrogen 3.170 N/A THR 130.A OG1 TYR 133.A O no hydrogen 2.645 N/A HIS 131.A N GLU 128.A O no hydrogen 3.435 N/A HIS 131.A ND1 SER 96.A O no hydrogen 3.270 N/A GLY 132.A N THR 127.A O no hydrogen 2.758 N/A TYR 133.A N THR 130.A OG1 no hydrogen 2.966 N/A THR 134.A N GLN 137.A OE1 no hydrogen 2.817 N/A THR 134.A OG1 GLN 137.A OE1 no hydrogen 3.475 N/A GLU 136.A N GLU 136.A OE1 no hydrogen 2.888 N/A GLN 137.A N THR 134.A OG1 no hydrogen 3.120 N/A ALA 138.A N THR 134.A O no hydrogen 2.847 N/A TRP 139.A N LEU 135.A O no hydrogen 2.794 N/A TRP 139.A NE1 SER 171.A OG no hydrogen 2.959 N/A GLU 140.A N GLU 136.A O no hydrogen 2.867 N/A ALA 141.A N GLN 137.A O no hydrogen 3.047 N/A LEU 142.A N ALA 138.A O no hydrogen 3.205 N/A VAL 143.A N TRP 139.A O no hydrogen 2.926 N/A GLU 144.A N GLU 140.A O no hydrogen 2.869 N/A ALA 145.A N ALA 141.A O no hydrogen 2.950 N/A LYS 146.A N LEU 142.A O no hydrogen 2.823 N/A LYS 146.A NZ ARG 152.A O no hydrogen 2.884 N/A LYS 147.A N VAL 143.A O no hydrogen 2.951 N/A ALA 148.A N GLU 144.A O no hydrogen 2.803 N/A GLY 149.A N LYS 146.A O no hydrogen 3.120 N/A LYS 150.A N ALA 145.A O no hydrogen 3.117 N/A LYS 150.A NZ ASP 104.A OD1 no hydrogen 2.693 N/A VAL 151.A N ALA 145.A O no hydrogen 3.364 N/A ARG 152.A N VAL 115.A O no hydrogen 3.074 N/A ARG 152.A NH1 ARG 8.A O no hydrogen 2.922 N/A ARG 152.A NH1 ASP 116.A OD1 no hydrogen 2.834 N/A ARG 152.A NH2 ARG 8.A O no hydrogen 3.193 N/A GLU 153.A N ASP 116.A O no hydrogen 2.852 N/A GLY 155.A N PHE 118.A O no hydrogen 3.081 N/A ILE 156.A N VAL 180.A O no hydrogen 3.016 N/A SER 157.A N ILE 120.A O no hydrogen 2.810 N/A SER 157.A OG ASN 158.A OD1 no hydrogen 3.162 N/A SER 157.A OG GLN 182.A O no hydrogen 2.690 N/A ASN 158.A N GLN 182.A O no hydrogen 2.805 N/A ALA 159.A N ASN 181.A OD1 no hydrogen 3.230 N/A ALA 160.A N HIS 163.A ND1 no hydrogen 2.967 N/A HIS 163.A N ALA 160.A O no hydrogen 2.957 N/A LEU 164.A N ALA 160.A O no hydrogen 3.078 N/A GLU 165.A N ILE 161.A O no hydrogen 2.993 N/A LYS 166.A N PRO 162.A O no hydrogen 3.167 N/A LEU 167.A N HIS 163.A O no hydrogen 2.989 N/A PHE 168.A N LEU 164.A O no hydrogen 2.963 N/A ALA 169.A N GLU 165.A O no hydrogen 3.016 N/A ALA 170.A N LYS 166.A O no hydrogen 2.963 N/A SER 171.A N PHE 168.A O no hydrogen 3.228 N/A SER 171.A OG LEU 167.A O no hydrogen 2.899 N/A SER 171.A OG TYR 176.A O no hydrogen 2.903 N/A TYR 176.A N SER 173.A O no hydrogen 2.773 N/A TYR 177.A N PRO 174.A O no hydrogen 3.085 N/A VAL 179.A N ILE 154.A O no hydrogen 3.051 N/A ASN 181.A N LEU 206.A O no hydrogen 2.966 N/A ASN 181.A ND2 ALA 159.A O no hydrogen 3.001 N/A GLN 182.A N ILE 156.A O no hydrogen 3.012 N/A ILE 183.A N GLU 208.A O no hydrogen 2.874 N/A PHE 185.A N PHE 210.A O no hydrogen 3.188 N/A HIS 186.A N LEU 189.A O no hydrogen 3.474 N/A HIS 186.A NE2 GLU 184.A OE2 no hydrogen 2.834 N/A PHE 188.A N HIS 186.A ND1 no hydrogen 3.167 N/A LEU 189.A N HIS 186.A O no hydrogen 2.990 N/A GLN 190.A NE2 PRO 187.A O no hydrogen 2.876 N/A GLN 190.A NE2 ASN 284.A O no hydrogen 2.808 N/A LYS 194.A N LEU 303.A O no hydrogen 2.723 N/A ILE 196.A N SER 193.A O no hydrogen 3.094 N/A ARG 198.A NE GLU 202.A OE2 no hydrogen 2.415 N/A PHE 199.A N ASN 195.A O no hydrogen 3.033 N/A CYS 200.A N ILE 196.A O no hydrogen 2.879 N/A CYS 200.A SG ILE 196.A O no hydrogen 3.304 N/A GLN 201.A N VAL 197.A O no hydrogen 2.922 N/A GLN 201.A NE2 ARG 250.A O no hydrogen 3.127 N/A GLN 201.A NE2 GLY 251.A O no hydrogen 3.457 N/A GLU 202.A N ARG 198.A O no hydrogen 2.990 N/A HIS 203.A N CYS 200.A O no hydrogen 3.027 N/A ILE 205.A N CYS 200.A O no hydrogen 2.912 N/A LEU 206.A N VAL 179.A O no hydrogen 2.866 N/A GLU 208.A N ASN 181.A O no hydrogen 3.084 N/A ALA 209.A N LEU 253.A O no hydrogen 2.855 N/A PHE 210.A N ILE 183.A O no hydrogen 2.866 N/A ALA 214.A N SER 211.A O no hydrogen 3.133 N/A LEU 216.A N LEU 213.A O no hydrogen 2.730 N/A ALA 217.A N LEU 213.A O no hydrogen 2.830 N/A ARG 218.A N ALA 214.A O no hydrogen 2.705 N/A VAL 219.A N ALA 214.A O no hydrogen 3.224 N/A LEU 224.A N ASN 222.A OD1 no hydrogen 2.806 N/A ALA 225.A N ASN 222.A O no hydrogen 2.966 N/A THR 227.A OG1 GLU 282.A OE2 no hydrogen 2.791 N/A LEU 228.A N LEU 224.A O no hydrogen 2.802 N/A LYS 229.A N ALA 225.A O no hydrogen 2.896 N/A LYS 229.A NZ GLU 233.A OE2 no hydrogen 2.855 N/A ARG 230.A N GLU 226.A O no hydrogen 2.891 N/A ARG 230.A NH1 GLU 282.A OE1 no hydrogen 3.260 N/A ARG 230.A NH1 GLU 282.A OE2 no hydrogen 2.938 N/A ARG 230.A NH2 GLU 282.A OE1 no hydrogen 2.665 N/A LEU 231.A N THR 227.A O no hydrogen 2.965 N/A ALA 232.A N LEU 228.A O no hydrogen 2.750 N/A GLU 233.A N LYS 229.A O no hydrogen 2.855 N/A LYS 234.A N ARG 230.A O no hydrogen 2.986 N/A LYS 234.A NZ TYR 235.A OH no hydrogen 3.028 N/A LYS 234.A NZ GLU 279.A OE1 no hydrogen 2.837 N/A TYR 235.A N LEU 231.A O no hydrogen 2.976 N/A TYR 235.A OH GLU 279.A OE1 no hydrogen 3.369 N/A TYR 235.A OH GLU 279.A OE2 no hydrogen 2.567 N/A LYS 236.A N GLU 233.A O no hydrogen 3.248 N/A LYS 236.A NZ GLU 233.A O no hydrogen 2.746 N/A LYS 237.A N ALA 232.A O no hydrogen 2.967 N/A LYS 237.A NZ ASN 269.A O no hydrogen 2.860 N/A LYS 237.A NZ ASP 272.A OD1 no hydrogen 2.625 N/A LYS 237.A NZ ASP 272.A OD2 no hydrogen 3.120 N/A THR 238.A N GLN 241.A OE1 no hydrogen 2.813 N/A THR 238.A OG1 GLN 241.A OE1 no hydrogen 3.461 N/A GLU 239.A N GLU 239.A OE1 no hydrogen 2.781 N/A GLN 241.A N THR 238.A OG1 no hydrogen 3.081 N/A GLN 241.A NE2 GLU 266.A O no hydrogen 2.960 N/A VAL 242.A N THR 238.A O no hydrogen 3.012 N/A LEU 243.A N GLU 239.A O no hydrogen 3.068 N/A LEU 244.A N ALA 240.A O no hydrogen 2.950 N/A ARG 245.A N GLN 241.A O no hydrogen 2.944 N/A ARG 245.A NH1 LEU 270.A O no hydrogen 2.949 N/A TYR 246.A N VAL 242.A O no hydrogen 2.890 N/A TYR 246.A OH ASN 284.A OD1 no hydrogen 2.687 N/A THR 247.A N LEU 243.A O no hydrogen 2.920 N/A THR 247.A OG1 LEU 243.A O no hydrogen 2.763 N/A LEU 248.A N LEU 244.A O no hydrogen 3.066 N/A GLN 249.A N ARG 245.A O no hydrogen 2.782 N/A ARG 250.A N TYR 246.A O no hydrogen 3.050 N/A ARG 250.A NH1 TYR 246.A OH no hydrogen 3.528 N/A ARG 250.A NH1 ASN 284.A OD1 no hydrogen 3.175 N/A GLY 251.A N LEU 248.A O no hydrogen 2.869 N/A ILE 252.A N THR 247.A O no hydrogen 3.171 N/A LEU 253.A N VAL 207.A O no hydrogen 2.989 N/A VAL 255.A N ALA 209.A O no hydrogen 2.746 N/A THR 256.A N ALA 18.A O no hydrogen 3.024 N/A THR 257.A OG1 GLY 20.A O no hydrogen 2.740 N/A LYS 260.A N SER 258.A OG no hydrogen 3.128 N/A LEU 264.A N LYS 260.A O no hydrogen 3.049 N/A LYS 265.A N GLU 261.A O no hydrogen 2.931 N/A GLU 266.A N SER 262.A O no hydrogen 2.920 N/A SER 267.A N ARG 263.A O no hydrogen 2.800 N/A SER 267.A OG ARG 263.A O no hydrogen 2.941 N/A LEU 268.A N LYS 265.A O no hydrogen 3.205 N/A ASN 269.A N GLU 266.A O no hydrogen 2.969 N/A LEU 270.A N LEU 268.A O no hydrogen 3.015 N/A THR 276.A N GLU 279.A OE2 no hydrogen 2.843 N/A GLU 279.A N THR 276.A OG1 no hydrogen 3.128 N/A VAL 280.A N THR 276.A O no hydrogen 2.794 N/A ASN 281.A N ASP 277.A O no hydrogen 2.883 N/A GLU 282.A N GLU 278.A O no hydrogen 2.817 N/A ILE 283.A N GLU 279.A O no hydrogen 3.069 N/A ASN 284.A N VAL 280.A O no hydrogen 2.870 N/A ASN 284.A ND2 ASN 281.A OD1 no hydrogen 3.697 N/A LYS 285.A N ASN 281.A O no hydrogen 2.932 N/A ILE 286.A N GLU 282.A O no hydrogen 3.048 N/A GLY 287.A N ILE 283.A O no hydrogen 2.902 N/A ASP 288.A N ASN 284.A O no hydrogen 2.860 N/A ALA 289.A N LYS 285.A O no hydrogen 3.228 N/A ASN 290.A N GLY 287.A O no hydrogen 3.135 N/A ASN 290.A ND2 ILE 286.A O no hydrogen 2.891 N/A TYR 292.A N PHE 188.A O no hydrogen 3.005 N/A ARG 293.A NH1 GLN 192.A O no hydrogen 2.971 N/A ARG 293.A NH2 GLN 192.A O no hydrogen 3.003 N/A ALA 294.A N GLU 184.A OE2 no hydrogen 2.701 N/A PHE 295.A N GLU 184.A OE1 no hydrogen 2.994 N/A HIS 297.A NE2 ARG 293.A O no hydrogen 2.658 N/A PHE 300.A N PHE 296.A O no hydrogen 3.117 N/A LYS 301.A N GLU 298.A O no hydrogen 3.389 N/A LYS 301.A NZ GLU 298.A OE1 no hydrogen 3.044 N/A LYS 301.A NZ GLU 298.A OE2 no hydrogen 2.308 N/A LEU 303.A N PHE 300.A O no hydrogen 2.908 N/A