Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4hzs_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): GLN 1.A NE2 ASP 58.A O no hydrogen 3.281 N/A THR 4.A N ASN 65.A OD1 no hydrogen 2.511 N/A THR 4.A OG1 ASN 65.A OD1 no hydrogen 2.787 N/A ILE 7.A N VAL 81.A O no hydrogen 2.991 N/A LYS 10.A NZ ASP 11.A OD1 no hydrogen 3.126 N/A ASP 11.A N GLY 8.A O no hydrogen 2.669 N/A LEU 12.A N GLU 9.A O no hydrogen 3.228 N/A ARG 13.A N GLU 30.A O no hydrogen 3.024 N/A ARG 13.A NH2 ASP 32.A OD1 no hydrogen 2.678 N/A LEU 15.A N ARG 28.A O no hydrogen 2.993 N/A LEU 18.A N VAL 26.A O no hydrogen 2.803 N/A GLY 24.A N GLY 21.A O no hydrogen 3.024 N/A VAL 25.A N CYS 45.A O no hydrogen 3.308 N/A VAL 26.A N GLY 19.A O no hydrogen 3.496 N/A ARG 27.A N VAL 43.A O no hydrogen 2.998 N/A ARG 27.A NE LEU 15.A O no hydrogen 3.428 N/A GLU 30.A N ARG 13.A O no hydrogen 2.978 N/A TRP 31.A N VAL 39.A O no hydrogen 3.045 N/A ASP 32.A N ASP 11.A O no hydrogen 2.888 N/A ALA 33.A N LYS 37.A O no hydrogen 2.872 N/A GLY 36.A N ALA 33.A O no hydrogen 2.774 N/A THR 38.A OG1 ASP 32.A OD2 no hydrogen 3.252 N/A VAL 39.A N TRP 31.A O no hydrogen 2.884 N/A VAL 41.A N GLY 29.A O no hydrogen 3.022 N/A ALA 42.A N THR 91.A O no hydrogen 3.025 N/A VAL 43.A N ARG 27.A O no hydrogen 2.885 N/A LYS 44.A N MET 89.A O no hydrogen 3.120 N/A CYS 45.A N VAL 25.A O no hydrogen 2.822 N/A CYS 45.A SG VAL 25.A O no hydrogen 3.400 N/A CYS 45.A SG VAL 43.A O no hydrogen 3.856 N/A LEU 46.A N MET 87.A O no hydrogen 2.966 N/A ASP 59.A N GLU 55.A O no hydrogen 2.885 N/A ILE 61.A N MET 57.A O no hydrogen 3.109 N/A ARG 62.A N ASP 58.A O no hydrogen 3.054 N/A ARG 62.A NH1 ASP 59.A OD1 no hydrogen 3.326 N/A GLU 63.A N ASP 59.A O no hydrogen 2.807 N/A VAL 64.A N PHE 60.A O no hydrogen 2.782 N/A ASN 65.A N ILE 61.A O no hydrogen 2.927 N/A ASN 65.A ND2 SER 2.A O no hydrogen 3.186 N/A MET 67.A N GLU 63.A O no hydrogen 3.011 N/A HIS 68.A N VAL 64.A O no hydrogen 2.755 N/A SER 69.A OG ASN 65.A O no hydrogen 3.066 N/A SER 69.A OG ALA 66.A O no hydrogen 2.707 N/A LEU 70.A N MET 67.A O no hydrogen 2.889 N/A ASP 71.A N TYR 128.A OH no hydrogen 2.819 N/A HIS 72.A NE2 ASN 74.A OD1 no hydrogen 3.201 N/A ASN 74.A ND2 GLN 121.A OE1 no hydrogen 3.318 N/A ASN 74.A ND2 VAL 152.A O no hydrogen 2.936 N/A LEU 75.A N HIS 72.A O no hydrogen 3.036 N/A ILE 76.A N ILE 154.A O no hydrogen 2.823 N/A ARG 77.A N GLU 92.A OE2 no hydrogen 3.030 N/A ARG 77.A NH2 TYR 79.A OH no hydrogen 3.124 N/A TYR 79.A N VAL 90.A O no hydrogen 2.766 N/A GLY 80.A N VAL 90.A O no hydrogen 3.168 N/A VAL 81.A N CYS 5.A O no hydrogen 2.958 N/A VAL 82.A N LYS 88.A O no hydrogen 3.026 N/A LYS 88.A NZ PRO 86.A O no hydrogen 3.112 N/A MET 89.A N LYS 44.A O no hydrogen 2.812 N/A VAL 90.A N GLY 80.A O no hydrogen 2.857 N/A THR 91.A N ALA 42.A O no hydrogen 2.937 N/A THR 91.A OG1 ALA 42.A O no hydrogen 3.277 N/A THR 91.A OG1 GLU 92.A O no hydrogen 2.903 N/A GLU 92.A N ARG 77.A O no hydrogen 2.682 N/A SER 98.A OG ASP 101.A OD2 no hydrogen 3.506 N/A LEU 99.A N LEU 144.A O no hydrogen 2.740 N/A ARG 102.A N SER 98.A O no hydrogen 3.458 N/A ARG 102.A NE LEU 96.A O no hydrogen 2.872 N/A ARG 102.A NH2 LEU 96.A O no hydrogen 2.901 N/A LEU 103.A N LEU 99.A O no hydrogen 3.135 N/A ARG 104.A N LEU 100.A O no hydrogen 3.127 N/A ARG 104.A NE GLY 200.A O no hydrogen 2.910 N/A LYS 105.A N ARG 102.A O no hydrogen 3.096 N/A HIS 106.A N ARG 102.A O no hydrogen 3.130 N/A HIS 109.A N HIS 106.A O no hydrogen 2.798 N/A LEU 112.A N GLN 301.A OE1 no hydrogen 2.716 N/A LEU 115.A N LEU 111.A O no hydrogen 3.192 N/A SER 116.A N LEU 112.A O no hydrogen 3.034 N/A SER 116.A OG GLN 262.A OE1 no hydrogen 2.665 N/A ARG 117.A N GLY 113.A O no hydrogen 3.207 N/A TYR 118.A N THR 114.A O no hydrogen 2.880 N/A TYR 118.A OH ARG 149.A O no hydrogen 2.509 N/A ALA 119.A N LEU 115.A O no hydrogen 2.807 N/A VAL 120.A N SER 116.A O no hydrogen 3.138 N/A GLN 121.A N ARG 117.A O no hydrogen 2.906 N/A GLN 121.A NE2 ASP 150.A O no hydrogen 3.051 N/A VAL 122.A N TYR 118.A O no hydrogen 2.971 N/A ALA 123.A N ALA 119.A O no hydrogen 3.162 N/A GLU 124.A N VAL 120.A O no hydrogen 3.132 N/A GLU 124.A N GLN 121.A O no hydrogen 2.602 N/A GLY 125.A N GLN 121.A O no hydrogen 2.870 N/A MET 126.A N VAL 122.A O no hydrogen 3.029 N/A GLY 127.A N ALA 123.A O no hydrogen 2.956 N/A TYR 128.A N GLU 124.A O no hydrogen 3.222 N/A TYR 128.A N GLY 125.A O no hydrogen 3.161 N/A LEU 129.A N GLY 125.A O no hydrogen 3.197 N/A GLU 130.A N MET 126.A O no hydrogen 2.650 N/A SER 131.A N GLY 127.A O no hydrogen 3.168 N/A SER 131.A OG TYR 128.A O no hydrogen 2.959 N/A LYS 132.A N TYR 128.A O no hydrogen 3.103 N/A ARG 133.A N GLU 130.A O no hydrogen 2.929 N/A PHE 134.A N LEU 129.A O no hydrogen 2.861 N/A HIS 136.A N ASP 185.A OD2 no hydrogen 2.795 N/A HIS 136.A NE2 GLY 155.A O no hydrogen 3.177 N/A ARG 137.A N ASP 185.A OD1 no hydrogen 3.275 N/A ASP 138.A N HIS 136.A ND1 no hydrogen 2.848 N/A ALA 141.A N GLU 195.A OE2 no hydrogen 2.743 N/A ARG 142.A NH2 ASP 138.A OD2 no hydrogen 3.429 N/A ASN 143.A N ALA 140.A O no hydrogen 2.959 N/A ASN 143.A ND2 ASP 138.A O no hydrogen 2.883 N/A ASN 143.A ND2 ASP 138.A OD2 no hydrogen 3.197 N/A LEU 144.A N ALA 141.A O no hydrogen 2.968 N/A LEU 145.A N LYS 153.A O no hydrogen 2.830 N/A LEU 146.A N GLY 97.A O no hydrogen 3.045 N/A ALA 147.A N LEU 151.A O no hydrogen 2.857 N/A ASP 150.A N THR 148.A OG1 no hydrogen 2.638 N/A VAL 152.A N GLN 121.A OE1 no hydrogen 2.680 N/A LYS 153.A N LEU 145.A O no hydrogen 2.836 N/A LYS 153.A NZ ARG 73.A O no hydrogen 2.731 N/A ILE 154.A N ASN 74.A O no hydrogen 2.670 N/A GLY 155.A N ASN 143.A O no hydrogen 2.763 N/A GLY 158.A N HIS 136.A O no hydrogen 2.939 N/A LEU 159.A N ASP 156.A O no hydrogen 3.293 N/A ARG 161.A N GLY 158.A O no hydrogen 3.252 N/A LEU 163.A N LEU 159.A O no hydrogen 3.027 N/A TRP 169.A N PRO 166.A O no hydrogen 2.765 N/A TRP 169.A NE1 GLU 195.A OE2 no hydrogen 2.917 N/A CYS 170.A N PHE 167.A O no hydrogen 3.271 N/A CYS 170.A SG PRO 166.A O no hydrogen 3.339 N/A GLU 173.A N GLU 173.A OE1 no hydrogen 2.598 N/A SER 174.A OG THR 179.A O no hydrogen 3.110 N/A LEU 175.A N ALA 171.A O no hydrogen 3.018 N/A LYS 176.A N PRO 172.A O no hydrogen 2.695 N/A LYS 176.A NZ ASP 217.A OD2 no hydrogen 3.536 N/A THR 177.A N GLU 173.A O no hydrogen 2.816 N/A THR 177.A OG1 GLU 173.A O no hydrogen 3.089 N/A THR 177.A OG1 THR 179.A OG1 no hydrogen 2.833 N/A ARG 178.A N SER 174.A O no hydrogen 2.716 N/A THR 179.A N THR 177.A OG1 no hydrogen 3.342 N/A THR 179.A OG1 THR 177.A OG1 no hydrogen 2.833 N/A SER 184.A N SER 181.A OG no hydrogen 3.025 N/A ASP 185.A N SER 181.A O no hydrogen 2.931 N/A THR 186.A N HIS 182.A O no hydrogen 3.190 N/A THR 186.A OG1 HIS 182.A O no hydrogen 3.143 N/A THR 186.A OG1 PRO 249.A O no hydrogen 3.422 N/A TRP 187.A N ALA 183.A O no hydrogen 3.343 N/A MET 188.A N SER 184.A O no hydrogen 3.303 N/A PHE 189.A N ASP 185.A O no hydrogen 2.756 N/A GLY 190.A N THR 186.A O no hydrogen 2.904 N/A VAL 191.A N TRP 187.A O no hydrogen 3.364 N/A THR 192.A N MET 188.A O no hydrogen 2.866 N/A THR 192.A OG1 MET 188.A O no hydrogen 3.316 N/A LEU 193.A N PHE 189.A O no hydrogen 3.221 N/A TRP 194.A N GLY 190.A O no hydrogen 3.023 N/A TRP 194.A NE1 PRO 224.A O no hydrogen 2.835 N/A GLU 195.A N VAL 191.A O no hydrogen 2.794 N/A MET 196.A N THR 192.A O no hydrogen 2.890 N/A PHE 197.A N LEU 193.A O no hydrogen 3.007 N/A THR 198.A N TRP 194.A O no hydrogen 3.031 N/A THR 198.A N GLU 195.A O no hydrogen 3.326 N/A THR 198.A OG1 TRP 194.A O no hydrogen 3.293 N/A THR 198.A OG1 GLU 195.A O no hydrogen 3.061 N/A TYR 199.A N MET 196.A O no hydrogen 2.842 N/A TYR 199.A OH ASP 228.A OD2 no hydrogen 3.067 N/A GLY 200.A N GLU 195.A O no hydrogen 2.698 N/A GLN 201.A N THR 198.A O no hydrogen 3.172 N/A GLN 201.A N THR 198.A OG1 no hydrogen 3.043 N/A LEU 207.A N TRP 204.A O no hydrogen 3.275 N/A ASN 208.A N GLN 211.A OE1 no hydrogen 3.092 N/A GLN 211.A N ASN 208.A O no hydrogen 3.138 N/A GLN 211.A N ASN 208.A OD1 no hydrogen 3.058 N/A ILE 212.A N ASN 208.A O no hydrogen 3.019 N/A LEU 213.A N GLY 209.A O no hydrogen 2.782 N/A HIS 214.A N GLN 211.A O no hydrogen 3.103 N/A LYS 215.A N GLN 211.A O no hydrogen 3.173 N/A LYS 215.A NZ GLU 221.A OE1 no hydrogen 2.769 N/A ILE 216.A N ILE 212.A O no hydrogen 3.011 N/A ASP 217.A N LEU 213.A O no hydrogen 2.981 N/A LYS 218.A N HIS 214.A O no hydrogen 3.167 N/A GLU 219.A N HIS 214.A O no hydrogen 3.142 N/A GLU 221.A N LYS 215.A O no hydrogen 2.806 N/A ARG 222.A NE TRP 241.A O no hydrogen 2.996 N/A ARG 222.A NH1 ILE 216.A O no hydrogen 2.888 N/A ARG 222.A NH1 GLU 221.A O no hydrogen 2.661 N/A ARG 222.A NH2 ILE 216.A O no hydrogen 3.506 N/A ARG 222.A NH2 TRP 241.A O no hydrogen 3.303 N/A ARG 225.A NH1 CYS 229.A O no hydrogen 3.391 N/A CYS 229.A N PRO 226.A O no hydrogen 3.190 N/A CYS 229.A SG PRO 230.A O no hydrogen 3.530 N/A GLN 231.A NE2 ASN 235.A OD1 no hydrogen 2.931 N/A TYR 234.A N PRO 230.A O no hydrogen 2.955 N/A TYR 234.A OH LEU 223.A O no hydrogen 2.707 N/A ASN 235.A N GLN 231.A O no hydrogen 2.744 N/A MET 237.A N ILE 233.A O no hydrogen 3.126 N/A VAL 238.A N TYR 234.A O no hydrogen 3.017 N/A GLN 239.A N ASN 235.A O no hydrogen 3.083 N/A GLN 239.A NE2 GLN 239.A O no hydrogen 3.574 N/A GLN 239.A NE2 ASP 247.A O no hydrogen 3.465 N/A CYS 240.A N VAL 236.A O no hydrogen 3.253 N/A CYS 240.A N MET 237.A O no hydrogen 2.776 N/A CYS 240.A SG VAL 236.A O no hydrogen 3.295 N/A TRP 241.A N MET 237.A O no hydrogen 3.256 N/A TRP 241.A N VAL 238.A O no hydrogen 3.001 N/A ASP 247.A N LYS 244.A O no hydrogen 2.907 N/A ARG 248.A N PRO 245.A O no hydrogen 3.132 N/A ARG 248.A NE ALA 242.A O no hydrogen 2.780 N/A ARG 248.A NH1 GLU 173.A OE2 no hydrogen 2.653 N/A ARG 248.A NH1 ALA 183.A O no hydrogen 3.291 N/A ARG 248.A NH2 GLU 173.A OE1 no hydrogen 2.973 N/A ARG 248.A NH2 GLU 173.A OE2 no hydrogen 3.236 N/A ARG 248.A NH2 ALA 242.A O no hydrogen 3.312 N/A PHE 251.A N GLU 130.A OE1 no hydrogen 3.294 N/A LEU 254.A N THR 250.A O no hydrogen 2.957 N/A ARG 255.A N PHE 251.A O no hydrogen 2.999 N/A ARG 255.A NE ASP 256.A OD1 no hydrogen 3.227 N/A ARG 255.A NH1 GLU 124.A OE2 no hydrogen 2.871 N/A ARG 255.A NH2 ASP 256.A OD1 no hydrogen 2.738 N/A ASP 256.A N VAL 252.A O no hydrogen 3.235 N/A PHE 257.A N ALA 253.A O no hydrogen 3.101 N/A LEU 258.A N LEU 254.A O no hydrogen 2.957 N/A LEU 258.A N ARG 255.A O no hydrogen 3.229 N/A LEU 259.A N ARG 255.A O no hydrogen 3.072 N/A GLU 260.A N ASP 256.A O no hydrogen 2.980 N/A ALA 261.A N LEU 258.A O no hydrogen 3.177 N/A GLN 262.A N LEU 259.A O no hydrogen 3.407 N/A MET 266.A N ILE 286.A O no hydrogen 2.741 N/A ALA 268.A N ASP 284.A O no hydrogen 2.581 N/A LEU 269.A N VAL 315.A O no hydrogen 2.890 N/A PHE 272.A N ILE 280.A O no hydrogen 2.759 N/A LEU 278.A N PRO 310.A O no hydrogen 2.901 N/A ILE 280.A N PHE 272.A O no hydrogen 3.056 N/A GLN 281.A N ASP 284.A OD2 no hydrogen 3.356 N/A MET 282.A N ASP 271.A OD2 no hydrogen 3.163 N/A ASN 283.A N ALA 268.A O no hydrogen 3.157 N/A ASP 284.A N GLN 281.A O no hydrogen 3.129 N/A ILE 286.A N MET 266.A O no hydrogen 2.479 N/A THR 287.A N GLN 301.A O no hydrogen 2.954 N/A THR 287.A OG1 ASP 265.A OD2 no hydrogen 2.616 N/A VAL 288.A N THR 264.A O no hydrogen 3.186 N/A ILE 289.A N ARG 299.A O no hydrogen 2.679 N/A GLU 290.A N ARG 299.A O no hydrogen 3.336 N/A TRP 298.A N PHE 311.A O no hydrogen 2.863 N/A TRP 298.A NE1 ARG 292.A O no hydrogen 2.840 N/A ARG 299.A N GLU 290.A O no hydrogen 2.973 N/A ARG 299.A NE ASP 228.A OD1 no hydrogen 3.434 N/A ARG 299.A NH2 ASP 228.A OD1 no hydrogen 3.417 N/A GLY 300.A N GLY 309.A O no hydrogen 3.089 N/A GLN 301.A N THR 287.A O no hydrogen 2.773 N/A GLN 301.A NE2 PHE 110.A O no hydrogen 2.739 N/A GLN 301.A NE2 LEU 306.A O no hydrogen 3.483 N/A ASN 302.A N CYS 307.A O no hydrogen 2.867 N/A ASN 302.A ND2 HIS 279.A O no hydrogen 2.785 N/A ASN 302.A ND2 ASP 284.A OD2 no hydrogen 3.422 N/A THR 303.A N VAL 285.A O no hydrogen 3.249 N/A THR 303.A OG1 VAL 285.A O no hydrogen 3.087 N/A ARG 304.A N ASN 302.A OD1 no hydrogen 3.225 N/A ARG 304.A NE ASP 284.A OD1 no hydrogen 3.037 N/A ARG 304.A NH2 ASP 284.A OD1 no hydrogen 3.418 N/A THR 305.A OG1 ASN 302.A O no hydrogen 3.326 N/A CYS 307.A N THR 305.A OG1 no hydrogen 3.199 N/A CYS 307.A SG HIS 109.A NE2 no hydrogen 3.939 N/A GLY 309.A N GLY 300.A O no hydrogen 2.920 N/A PHE 311.A N TRP 298.A O no hydrogen 2.959 N/A ARG 313.A N TYR 296.A O no hydrogen 2.761 N/A ARG 313.A NE ALA 293.A O no hydrogen 3.196 N/A ARG 313.A NE GLU 294.A O no hydrogen 3.458 N/A ARG 313.A NH2 GLU 294.A O no hydrogen 3.026 N/A VAL 315.A N PRO 312.A O no hydrogen 3.255 N/A VAL 316.A N ARG 313.A O no hydrogen 3.189 N/A THR 317.A N ASN 314.A O no hydrogen 3.436 N/A