Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4kev_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ILE 3.A N ILE 11.A O no hydrogen 2.716 N/A VAL 6.A N LEU 90.A O no hydrogen 2.941 N/A LYS 8.A NZ GLY 87.A O no hydrogen 2.502 N/A LYS 8.A NZ ILE 88.A O no hydrogen 3.358 N/A LYS 8.A NZ ASN 89.A OD1 no hydrogen 2.872 N/A SER 10.A OG ILE 3.A O no hydrogen 2.768 N/A SER 10.A OG ILE 11.A O no hydrogen 3.518 N/A ILE 11.A N ILE 3.A O no hydrogen 3.089 N/A ASP 15.A N GLU 12.A O no hydrogen 2.731 N/A THR 19.A N PHE 304.A O no hydrogen 3.094 N/A LEU 20.A N THR 63.A O no hydrogen 2.874 N/A HIS 22.A N SER 253.A OG no hydrogen 3.086 N/A HIS 22.A NE2 HIS 24.A NE2 no hydrogen 2.983 N/A GLU 23.A N VAL 65.A O no hydrogen 3.265 N/A HIS 24.A N TYR 256.A O no hydrogen 2.963 N/A HIS 24.A ND1 THR 68.A OG1 no hydrogen 2.692 N/A HIS 24.A NE2 HIS 22.A NE2 no hydrogen 2.983 N/A LEU 25.A N ASP 66.A OD2 no hydrogen 3.079 N/A ARG 26.A NH2 GLU 45.A OE1 no hydrogen 2.664 N/A VAL 27.A N THR 259.A O no hydrogen 3.193 N/A PHE 28.A N LEU 72.A O no hydrogen 2.731 N/A SER 29.A N ASP 261.A OD2 no hydrogen 2.918 N/A GLU 30.A N GLU 30.A OE1 no hydrogen 2.415 N/A ARG 33.A N SER 29.A O no hydrogen 3.166 N/A ARG 33.A NH1 GLU 45.A OE1 no hydrogen 3.056 N/A ARG 33.A NH2 GLU 45.A OE1 no hydrogen 3.051 N/A GLN 34.A N GLU 30.A O no hydrogen 3.002 N/A GLN 34.A N ALA 31.A O no hydrogen 3.270 N/A GLN 35.A N ALA 31.A O no hydrogen 3.144 N/A TRP 36.A N VAL 32.A O no hydrogen 2.963 N/A LEU 39.A N TRP 36.A O no hydrogen 3.152 N/A TYR 40.A N PRO 37.A O no hydrogen 3.354 N/A TYR 40.A OH ASP 261.A OD2 no hydrogen 2.851 N/A GLU 44.A N ASN 41.A OD1 no hydrogen 3.213 N/A GLU 45.A N ASN 41.A O no hydrogen 2.855 N/A PHE 46.A N GLU 42.A O no hydrogen 2.576 N/A ARG 47.A N ASP 43.A O no hydrogen 3.077 N/A ASN 48.A N GLU 44.A O no hydrogen 3.289 N/A ASN 48.A ND2 GLU 44.A OE1 no hydrogen 2.582 N/A ALA 49.A N GLU 45.A O no hydrogen 3.054 N/A VAL 50.A N PHE 46.A O no hydrogen 3.083 N/A ASN 51.A N ARG 47.A O no hydrogen 2.951 N/A VAL 53.A N ALA 49.A O no hydrogen 3.104 N/A LYS 54.A N VAL 50.A O no hydrogen 3.084 N/A ARG 55.A N ASN 51.A O no hydrogen 3.226 N/A ALA 56.A N VAL 53.A O no hydrogen 3.046 N/A MET 57.A N VAL 53.A O no hydrogen 2.734 N/A GLN 58.A N LYS 54.A O no hydrogen 3.004 N/A GLY 60.A N MET 57.A O no hydrogen 2.908 N/A VAL 61.A N ALA 56.A O no hydrogen 3.329 N/A LYS 62.A N PHE 18.A O no hydrogen 2.634 N/A LYS 62.A NZ ASP 15.A O no hydrogen 3.014 N/A THR 63.A N PHE 18.A O no hydrogen 3.049 N/A THR 63.A OG1 ILE 16.A O no hydrogen 2.711 N/A ILE 64.A N ASN 89.A O no hydrogen 2.588 N/A VAL 65.A N LEU 20.A O no hydrogen 2.954 N/A ASP 66.A N VAL 91.A O no hydrogen 3.193 N/A THR 68.A N ASP 66.A OD1 no hydrogen 2.683 N/A THR 68.A OG1 HIS 24.A ND1 no hydrogen 2.692 N/A THR 68.A OG1 ASP 66.A OD1 no hydrogen 2.330 N/A THR 68.A OG1 ASP 66.A OD2 no hydrogen 3.310 N/A GLY 71.A N GLU 30.A OE2 no hydrogen 2.758 N/A LEU 72.A N VAL 69.A O no hydrogen 2.812 N/A GLY 73.A N GLU 30.A OE2 no hydrogen 3.018 N/A ARG 74.A NH1 GLY 93.A O no hydrogen 3.313 N/A ARG 74.A NH1 ASP 121.A OD2 no hydrogen 2.912 N/A ARG 74.A NH2 ASP 121.A OD2 no hydrogen 3.136 N/A ILE 76.A N GLN 127.A OE1 no hydrogen 2.879 N/A ARG 77.A NH1 GLN 127.A O no hydrogen 3.125 N/A ARG 77.A NH2 GLN 127.A O no hydrogen 3.034 N/A PHE 78.A N ASP 75.A OD1 no hydrogen 2.919 N/A MET 79.A N ASP 75.A O no hydrogen 3.036 N/A GLU 80.A N ILE 76.A O no hydrogen 2.908 N/A LYS 81.A N ARG 77.A O no hydrogen 3.211 N/A LYS 81.A NZ GLU 42.A OE2 no hydrogen 2.938 N/A VAL 82.A N PHE 78.A O no hydrogen 3.252 N/A VAL 83.A N MET 79.A O no hydrogen 3.166 N/A LYS 84.A N GLU 80.A O no hydrogen 3.097 N/A ALA 85.A N LYS 81.A O no hydrogen 2.844 N/A ALA 85.A N VAL 82.A O no hydrogen 3.220 N/A THR 86.A N VAL 83.A O no hydrogen 3.004 N/A THR 86.A OG1 VAL 82.A O no hydrogen 2.523 N/A THR 86.A OG1 VAL 83.A O no hydrogen 3.539 N/A GLY 87.A N VAL 83.A O no hydrogen 2.490 N/A ILE 88.A N THR 86.A OG1 no hydrogen 3.284 N/A VAL 91.A N ILE 64.A O no hydrogen 2.983 N/A THR 94.A N PHE 135.A O no hydrogen 2.912 N/A THR 94.A OG1 ASP 121.A OD2 no hydrogen 2.768 N/A GLY 95.A N THR 94.A OG1 no hydrogen 2.673 N/A TYR 97.A N MET 70.A O no hydrogen 2.874 N/A TYR 97.A OH TYR 99.A OH no hydrogen 2.155 N/A TYR 99.A OH TYR 97.A OH no hydrogen 2.155 N/A LEU 102.A N ASP 147.A OD2 no hydrogen 2.787 N/A PHE 106.A N PRO 103.A O no hydrogen 2.924 N/A LEU 107.A N PHE 104.A O no hydrogen 3.106 N/A ASN 108.A ND2 ASN 108.A O no hydrogen 2.344 N/A ARG 109.A N PHE 106.A O no hydrogen 3.286 N/A ARG 109.A NE TYR 105.A O no hydrogen 2.786 N/A ARG 109.A NH1 GLU 113.A OE2 no hydrogen 3.157 N/A SER 110.A N GLU 113.A OE1 no hydrogen 3.168 N/A GLU 113.A N SER 110.A OG no hydrogen 3.162 N/A ILE 114.A N SER 110.A O no hydrogen 3.261 N/A ALA 115.A N ILE 111.A O no hydrogen 2.901 N/A ASP 116.A N ASP 112.A O no hydrogen 2.847 N/A LEU 117.A N GLU 113.A O no hydrogen 3.438 N/A PHE 118.A N ILE 114.A O no hydrogen 3.285 N/A ILE 119.A N ALA 115.A O no hydrogen 2.720 N/A HIS 120.A N ASP 116.A O no hydrogen 2.685 N/A ASP 121.A N LEU 117.A O no hydrogen 3.216 N/A ILE 122.A N PHE 118.A O no hydrogen 3.086 N/A ILE 122.A N ILE 119.A O no hydrogen 3.246 N/A LYS 123.A N ILE 119.A O no hydrogen 2.769 N/A LYS 123.A NZ GLU 161.A OE1 no hydrogen 3.080 N/A GLY 125.A N HIS 120.A O no hydrogen 3.043 N/A GLN 127.A NE2 ARG 74.A O no hydrogen 3.175 N/A THR 129.A N ILE 126.A O no hydrogen 2.903 N/A LYS 132.A NZ LYS 123.A O no hydrogen 2.476 N/A LYS 132.A NZ GLU 124.A O no hydrogen 2.535 N/A ALA 133.A N ASP 121.A O no hydrogen 2.771 N/A GLY 134.A N ALA 92.A O no hydrogen 2.581 N/A VAL 136.A N PRO 165.A O no hydrogen 3.180 N/A ALA 139.A N HIS 169.A O no hydrogen 2.802 N/A GLU 141.A N ASP 140.A OD1 no hydrogen 2.407 N/A GLY 143.A N ASP 140.A O no hydrogen 2.629 N/A THR 145.A N GLY 143.A O no hydrogen 3.047 N/A THR 145.A OG1 ILE 100.A O no hydrogen 2.699 N/A VAL 148.A N THR 145.A OG1 no hydrogen 3.359 N/A GLU 149.A N THR 145.A O no hydrogen 2.894 N/A LYS 150.A N LYS 146.A O no hydrogen 3.105 N/A LYS 150.A NZ ARG 109.A O no hydrogen 3.479 N/A VAL 151.A N ASP 147.A O no hydrogen 3.204 N/A ILE 152.A N VAL 148.A O no hydrogen 3.232 N/A ARG 153.A N GLU 149.A O no hydrogen 3.074 N/A ARG 153.A NE GLU 149.A OE2 no hydrogen 3.265 N/A ARG 153.A NH1 GLU 187.A OE1 no hydrogen 2.558 N/A ARG 153.A NH2 GLU 149.A OE2 no hydrogen 2.604 N/A ALA 154.A N LYS 150.A O no hydrogen 2.960 N/A ALA 155.A N VAL 151.A O no hydrogen 2.826 N/A ALA 156.A N ILE 152.A O no hydrogen 3.022 N/A ILE 157.A N ARG 153.A O no hydrogen 3.078 N/A ALA 158.A N ALA 154.A O no hydrogen 3.161 N/A ASN 159.A N ALA 155.A O no hydrogen 2.943 N/A LYS 160.A N ALA 156.A O no hydrogen 3.147 N/A LYS 160.A NZ GLU 187.A O no hydrogen 2.037 N/A GLU 161.A N ILE 157.A O no hydrogen 2.934 N/A THR 162.A N ALA 158.A O no hydrogen 2.885 N/A THR 162.A N ASN 159.A O no hydrogen 3.185 N/A THR 162.A OG1 ALA 158.A O no hydrogen 2.473 N/A LYS 163.A N ASN 159.A O no hydrogen 2.369 N/A ILE 166.A N LYS 193.A O no hydrogen 2.780 N/A ILE 167.A N VAL 136.A O no hydrogen 2.989 N/A THR 168.A N LEU 195.A O no hydrogen 2.891 N/A THR 168.A OG1 GLN 180.A OE1 no hydrogen 2.999 N/A THR 168.A OG1 LEU 195.A O no hydrogen 3.271 N/A HIS 169.A N ILE 137.A O no hydrogen 2.787 N/A HIS 169.A NE2 ASP 140.A OD2 no hydrogen 3.114 N/A SER 170.A OG GLY 197.A O no hydrogen 2.786 N/A ASN 171.A N THR 176.A OG1 no hydrogen 2.978 N/A ASN 171.A ND2 ASP 140.A OD1 no hydrogen 2.851 N/A HIS 173.A N ASN 171.A OD1 no hydrogen 2.876 N/A ASN 174.A N ASN 171.A O no hydrogen 3.200 N/A ASN 174.A ND2 ASP 140.A O no hydrogen 2.571 N/A ASN 174.A ND2 GLU 141.A O no hydrogen 3.487 N/A THR 176.A N ASN 174.A OD1 no hydrogen 3.177 N/A THR 176.A OG1 ASN 171.A O no hydrogen 3.279 N/A THR 176.A OG1 ASN 174.A OD1 no hydrogen 2.553 N/A LEU 178.A N TYR 207.A OH no hydrogen 3.199 N/A GLU 179.A N ASN 175.A O no hydrogen 3.169 N/A GLN 180.A N THR 176.A O no hydrogen 2.930 N/A GLN 180.A NE2 HIS 169.A O no hydrogen 2.992 N/A GLN 181.A N GLY 177.A O no hydrogen 3.145 N/A GLN 181.A NE2 ILE 211.A O no hydrogen 2.802 N/A GLN 181.A NE2 SER 216.A OG no hydrogen 2.611 N/A ARG 182.A N LEU 178.A O no hydrogen 2.993 N/A ARG 182.A NE GLU 186.A OE1 no hydrogen 2.794 N/A ARG 182.A NH2 GLU 186.A OE2 no hydrogen 3.568 N/A ILE 183.A N GLU 179.A O no hydrogen 2.945 N/A LEU 184.A N GLN 180.A O no hydrogen 3.125 N/A THR 185.A N GLN 181.A O no hydrogen 2.911 N/A THR 185.A OG1 GLN 181.A O no hydrogen 2.915 N/A GLU 186.A N ARG 182.A O no hydrogen 2.924 N/A GLU 187.A N ILE 183.A O no hydrogen 2.968 N/A GLY 188.A N THR 185.A O no hydrogen 2.926 N/A VAL 189.A N LEU 184.A O no hydrogen 2.894 N/A GLY 192.A N ASP 190.A OD1 no hydrogen 2.929 N/A LYS 193.A N ASP 190.A O no hydrogen 2.539 N/A LYS 193.A NZ PHE 311.A O no hydrogen 2.894 N/A LYS 193.A NZ SER 313.A O no hydrogen 2.938 N/A ILE 194.A N PRO 191.A O no hydrogen 3.001 N/A LEU 195.A N ILE 166.A O no hydrogen 2.842 N/A ILE 196.A N PHE 217.A O no hydrogen 2.922 N/A GLY 197.A N THR 168.A OG1 no hydrogen 3.024 N/A HIS 198.A N ASP 221.A OD1 no hydrogen 2.707 N/A HIS 198.A N ASP 221.A OD2 no hydrogen 3.308 N/A HIS 198.A ND1 ASP 221.A OD1 no hydrogen 3.013 N/A LEU 199.A N GLY 219.A O no hydrogen 2.780 N/A GLY 200.A N GLY 219.A O no hydrogen 3.335 N/A ASN 204.A N THR 202.A OG1 no hydrogen 3.031 N/A TYR 207.A N ASN 204.A O no hydrogen 3.042 N/A ILE 208.A N ASN 204.A O no hydrogen 3.403 N/A LYS 209.A N ILE 205.A O no hydrogen 3.117 N/A LYS 209.A NZ ASP 244.A OD2 no hydrogen 2.574 N/A ILE 211.A N ILE 208.A O no hydrogen 3.226 N/A ALA 212.A N ILE 208.A O no hydrogen 3.147 N/A ASP 213.A N LYS 209.A O no hydrogen 2.635 N/A GLY 215.A N ALA 212.A O no hydrogen 2.757 N/A SER 216.A OG PRO 191.A O no hydrogen 3.028 N/A PHE 217.A N ILE 194.A O no hydrogen 2.998 N/A ILE 218.A N LYS 249.A O no hydrogen 2.795 N/A GLY 219.A N ILE 196.A O no hydrogen 2.699 N/A LEU 220.A N MET 251.A O no hydrogen 2.908 N/A ARG 222.A NE ASP 255.A OD2 no hydrogen 3.277 N/A ARG 222.A NH1 ASP 201.A OD2 no hydrogen 2.815 N/A TYR 223.A N SER 253.A O no hydrogen 3.370 N/A PHE 228.A N LEU 225.A O no hydrogen 3.354 N/A LYS 233.A N PRO 230.A O no hydrogen 3.296 N/A ARG 234.A N PRO 230.A O no hydrogen 2.918 N/A ARG 234.A NE LEU 229.A O no hydrogen 2.778 N/A ARG 234.A NH1 ASP 201.A OD1 no hydrogen 2.515 N/A ASN 235.A N VAL 231.A O no hydrogen 2.849 N/A THR 237.A N LYS 233.A O no hydrogen 3.202 N/A THR 237.A N ARG 234.A O no hydrogen 2.818 N/A THR 237.A OG1 LYS 233.A O no hydrogen 2.922 N/A THR 238.A N ARG 234.A O no hydrogen 2.792 N/A THR 238.A OG1 TYR 223.A OH no hydrogen 3.283 N/A THR 238.A OG1 ASN 235.A O no hydrogen 2.992 N/A LEU 239.A N ASN 235.A O no hydrogen 2.729 N/A ARG 240.A NE ASP 244.A OD2 no hydrogen 3.526 N/A LEU 241.A N THR 237.A O no hydrogen 3.517 N/A ILE 242.A N THR 238.A O no hydrogen 3.192 N/A LYS 243.A NZ ASN 293.A O no hydrogen 3.415 N/A ASP 244.A N ARG 240.A O no hydrogen 2.798 N/A GLY 245.A N ILE 242.A O no hydrogen 3.101 N/A TYR 246.A N LEU 241.A O no hydrogen 2.845 N/A TYR 246.A OH ASP 213.A OD1 no hydrogen 2.835 N/A LYS 249.A N TYR 246.A O no hydrogen 2.872 N/A LYS 249.A NZ ASP 248.A OD2 no hydrogen 3.469 N/A ILE 250.A N SER 247.A O no hydrogen 3.120 N/A MET 251.A N ILE 218.A O no hydrogen 3.288 N/A SER 253.A N LEU 220.A O no hydrogen 3.420 N/A SER 253.A OG HIS 22.A O no hydrogen 2.708 N/A SER 253.A OG GLU 23.A OE1 no hydrogen 2.355 N/A HIS 254.A N GLU 23.A OE1 no hydrogen 2.720 N/A HIS 254.A ND1 GLU 23.A OE1 no hydrogen 3.001 N/A ASP 255.A N HIS 22.A O no hydrogen 2.830 N/A TYR 256.A N GLU 23.A OE2 no hydrogen 3.060 N/A CYS 257.A SG ASP 255.A O no hydrogen 3.790 N/A CYS 258.A SG ASN 48.A O no hydrogen 3.925 N/A ALA 265.A N LEU 262.A O no hydrogen 3.020 N/A LYS 272.A N TYR 269.A O no hydrogen 2.845 N/A LEU 273.A N LYS 270.A O no hydrogen 2.991 N/A TRP 277.A N PRO 275.A O no hydrogen 2.649 N/A TRP 277.A NE1 HIS 254.A O no hydrogen 3.357 N/A LEU 281.A N SER 278.A O no hydrogen 3.385 N/A ILE 282.A N HIS 254.A NE2 no hydrogen 2.826 N/A GLU 284.A N THR 280.A O no hydrogen 3.093 N/A ASP 285.A N LEU 281.A O no hydrogen 2.918 N/A THR 286.A OG1 ASN 235.A OD1 no hydrogen 3.500 N/A ILE 287.A N ILE 282.A O no hydrogen 2.716 N/A PHE 289.A N ASP 285.A O no hydrogen 2.801 N/A LEU 290.A N THR 286.A O no hydrogen 2.864 N/A LYS 291.A N ILE 287.A O no hydrogen 2.935 N/A LYS 291.A NZ GLU 297.A OE1 no hydrogen 2.756 N/A ARG 292.A N PRO 288.A O no hydrogen 3.010 N/A ASN 293.A N PHE 289.A O no hydrogen 3.093 N/A ASN 293.A N LEU 290.A O no hydrogen 2.732 N/A GLY 294.A N LYS 291.A O no hydrogen 3.063 N/A GLU 298.A N GLU 298.A OE1 no hydrogen 2.634 N/A VAL 299.A N ASN 296.A OD1 no hydrogen 2.770 N/A ALA 301.A N GLU 297.A O no hydrogen 2.950 N/A THR 302.A N GLU 298.A O no hydrogen 3.027 N/A THR 302.A OG1 GLU 298.A O no hydrogen 3.160 N/A ILE 303.A N VAL 299.A O no hydrogen 3.004 N/A PHE 304.A N ILE 300.A O no hydrogen 3.071 N/A LYS 305.A N ALA 301.A O no hydrogen 2.815 N/A GLU 306.A N ALA 301.A O no hydrogen 3.073 N/A ASN 307.A N THR 302.A O no hydrogen 2.841 N/A ASN 307.A ND2 SER 247.A O no hydrogen 2.721 N/A ASN 307.A ND2 ILE 250.A O no hydrogen 2.490 N/A LYS 309.A N LYS 305.A O no hydrogen 3.133 N/A LYS 310.A N GLU 306.A O no hydrogen 2.899 N/A LYS 310.A NZ ASP 248.A O no hydrogen 3.139 N/A LYS 310.A NZ ASN 307.A OD1 no hydrogen 3.456 N/A PHE 311.A N ASN 307.A O no hydrogen 2.828 N/A PHE 312.A N PRO 308.A O no hydrogen 3.160 N/A SER 313.A N LYS 310.A O no hydrogen 3.461 N/A SER 313.A OG LYS 309.A O no hydrogen 2.612 N/A