Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4ork_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): THR 5.A OG1 ASP 1.A O no hydrogen 3.093 N/A ASN 6.A N ASP 2.A O no hydrogen 3.005 N/A ASN 6.A ND2 ASN 3.A OD1 no hydrogen 3.505 N/A VAL 7.A N ASN 3.A O no hydrogen 2.991 N/A LYS 8.A N ALA 4.A O no hydrogen 3.345 N/A ALA 9.A N THR 5.A O no hydrogen 3.221 N/A MET 10.A N ASN 6.A O no hydrogen 3.080 N/A LYS 11.A N VAL 7.A O no hydrogen 2.810 N/A TYR 12.A N LYS 8.A O no hydrogen 3.017 N/A LEU 13.A N ALA 9.A O no hydrogen 2.896 N/A ILE 14.A N MET 10.A O no hydrogen 3.115 N/A GLU 15.A N LYS 11.A O no hydrogen 3.258 N/A HIS 16.A N TYR 12.A O no hydrogen 2.964 N/A TYR 17.A N LEU 13.A O no hydrogen 3.065 N/A PHE 18.A N ILE 14.A O no hydrogen 2.965 N/A ASN 20.A N ASN 20.A OD1.A no hydrogen 2.449 N/A PHE 21.A N PHE 18.A O no hydrogen 3.047 N/A LYS 22.A NZ ASP 24.A OD1 no hydrogen 2.857 N/A VAL 23.A N GLU 15.A OE2 no hydrogen 2.735 N/A ASP 24.A N ASN 41.A OD1 no hydrogen 2.747 N/A SER 25.A N ASN 41.A OD1 no hydrogen 3.414 N/A GLU 27.A N LEU 39.A O no hydrogen 2.989 N/A ILE 29.A N ALA 37.A O no hydrogen 2.858 N/A SER 31.A OG GLY 32.A O no hydrogen 3.215 N/A SER 31.A OG SER 35.A O no hydrogen 3.392 N/A GLY 32.A N SER 35.A O no hydrogen 3.154 N/A SER 35.A OG THR 48.A O no hydrogen 3.327 N/A SER 35.A OG TYR 58.A OH no hydrogen 2.326 N/A VAL 36.A N THR 48.A O no hydrogen 3.072 N/A ALA 37.A N GLY 30.A O no hydrogen 2.762 N/A TYR 38.A N PHE 46.A O no hydrogen 2.801 N/A LEU 39.A N GLU 27.A O no hydrogen 2.921 N/A VAL 40.A N TYR 44.A O no hydrogen 2.745 N/A ASN 41.A N SER 25.A O no hydrogen 2.884 N/A ASN 41.A ND2 LYS 22.A O no hydrogen 3.163 N/A GLU 43.A N VAL 40.A O no hydrogen 3.121 N/A TYR 44.A N VAL 40.A O no hydrogen 2.946 N/A TYR 44.A OH GLU 82.A OE2 no hydrogen 2.369 N/A ILE 45.A N TYR 95.A O no hydrogen 2.667 N/A PHE 46.A N TYR 38.A O no hydrogen 2.784 N/A LYS 47.A N LEU 93.A O no hydrogen 3.040 N/A LYS 47.A NZ GLU 61.A OE1 no hydrogen 2.920 N/A LYS 47.A NZ GLU 61.A OE2 no hydrogen 3.502 N/A THR 48.A N VAL 36.A O no hydrogen 3.123 N/A LYS 49.A N SER 91.A O no hydrogen 3.415 N/A LYS 49.A NZ SER 51.A O no hydrogen 2.919 N/A LYS 49.A NZ SER 51.A OG no hydrogen 2.944 N/A LYS 49.A NZ ASN 53.A O no hydrogen 3.478 N/A PHE 50.A N ASP 34.A O no hydrogen 2.904 N/A SER 51.A N ASP 34.A O no hydrogen 3.224 N/A SER 51.A OG ASP 34.A O no hydrogen 3.492 N/A SER 51.A OG ASP 34.A OD1 no hydrogen 2.732 N/A THR 52.A N ASN 280.A OD1 no hydrogen 2.758 N/A THR 52.A OG1 THR 52.A O no hydrogen 2.368 N/A THR 52.A OG1 LYS 279.A O no hydrogen 3.271 N/A THR 52.A OG1 ASN 280.A OD1 no hydrogen 3.308 N/A LYS 55.A NZ ASN 148.A OD1 no hydrogen 2.859 N/A LYS 55.A NZ GLU 151.A OE1 no hydrogen 2.839 N/A LYS 55.A NZ GLU 151.A OE2 no hydrogen 3.344 N/A TYR 58.A OH SER 35.A OG no hydrogen 2.326 N/A LYS 60.A NZ LYS 55.A O no hydrogen 3.192 N/A GLU 61.A N GLY 57.A O no hydrogen 3.199 N/A LYS 62.A N TYR 58.A O no hydrogen 2.864 N/A LYS 62.A NZ SER 84.A OG no hydrogen 3.184 N/A ALA 63.A N ALA 59.A O no hydrogen 3.057 N/A ILE 64.A N LYS 60.A O no hydrogen 2.846 N/A TYR 65.A N GLU 61.A O no hydrogen 3.066 N/A TYR 65.A OH GLU 61.A OE1 no hydrogen 2.750 N/A ASN 66.A N LYS 62.A O no hydrogen 3.166 N/A PHE 67.A N ALA 63.A O no hydrogen 2.822 N/A LEU 68.A N ILE 64.A O no hydrogen 2.786 N/A ASN 69.A N TYR 65.A O no hydrogen 2.625 N/A ASN 69.A ND2 PRO 79.A O no hydrogen 2.940 N/A THR 70.A N PHE 67.A O no hydrogen 3.081 N/A THR 70.A OG1 ASN 66.A O no hydrogen 2.931 N/A ASN 71.A N PHE 67.A O no hydrogen 2.979 N/A LEU 72.A N LEU 68.A O no hydrogen 2.960 N/A GLU 73.A N GLN 129.A OE1 no hydrogen 2.635 N/A VAL 76.A N THR 74.A OG1 no hydrogen 3.275 N/A LYS 77.A N THR 210.A O no hydrogen 2.788 N/A LYS 77.A NZ LYS 99.A O no hydrogen 3.301 N/A GLU 82.A N GLY 94.A O no hydrogen 2.845 N/A TYR 83.A N GLY 94.A O no hydrogen 3.187 N/A TYR 85.A N ILE 92.A O no hydrogen 2.800 N/A SER 87.A N LEU 90.A O no hydrogen 3.212 N/A SER 87.A OG LEU 90.A O no hydrogen 3.091 N/A GLU 89.A N SER 87.A OG no hydrogen 3.266 N/A LEU 90.A N SER 87.A OG no hydrogen 3.004 N/A SER 91.A OG SER 87.A O no hydrogen 3.210 N/A ILE 92.A N TYR 85.A O no hydrogen 2.692 N/A LEU 93.A N LYS 47.A O no hydrogen 3.166 N/A GLY 94.A N TYR 83.A O no hydrogen 2.699 N/A TYR 95.A N ILE 45.A O no hydrogen 2.947 N/A GLU 97.A N GLU 43.A O no hydrogen 2.622 N/A LYS 99.A NZ GLU 97.A OE1 no hydrogen 2.489 N/A THR 101.A N LEU 203.A O no hydrogen 2.922 N/A LEU 103.A N LEU 201.A O no hydrogen 3.008 N/A ILE 107.A N THR 104.A OG1 no hydrogen 2.843 N/A TYR 108.A N THR 104.A O no hydrogen 3.048 N/A SER 109.A N PRO 105.A O no hydrogen 3.131 N/A SER 109.A OG GLU 106.A O no hydrogen 2.938 N/A THR 110.A N ILE 107.A O no hydrogen 3.309 N/A THR 110.A OG1 ILE 107.A O no hydrogen 3.173 N/A MET 111.A N TYR 108.A O no hydrogen 3.094 N/A GLU 115.A N SER 112.A OG no hydrogen 3.070 N/A GLN 116.A N SER 112.A O no hydrogen 2.912 N/A GLN 116.A NE2 TYR 108.A O no hydrogen 2.985 N/A ASN 117.A N GLU 113.A O no hydrogen 2.835 N/A LEU 118.A N GLU 114.A O no hydrogen 3.187 N/A LEU 119.A N GLU 115.A O no hydrogen 3.061 N/A LYS 120.A N GLN 116.A O no hydrogen 2.998 N/A LYS 120.A NZ ASN 117.A OD1 no hydrogen 3.476 N/A LYS 120.A NZ ASP 245.A OD2 no hydrogen 3.140 N/A ARG 121.A N ASN 117.A O no hydrogen 3.036 N/A ASP 122.A N LEU 118.A O no hydrogen 2.858 N/A ILE 123.A N LEU 119.A O no hydrogen 2.987 N/A ALA 124.A N LYS 120.A O no hydrogen 3.053 N/A SER 125.A N ARG 121.A O no hydrogen 2.874 N/A PHE 126.A N ASP 122.A O no hydrogen 2.834 N/A LEU 127.A N ILE 123.A O no hydrogen 2.969 N/A ARG 128.A N ALA 124.A O no hydrogen 2.910 N/A ARG 128.A NH1.B MET 249.A O no hydrogen 2.915 N/A ARG 128.A NH1.B TYR 250.A O no hydrogen 2.890 N/A ARG 128.A NH2.A TYR 250.A O no hydrogen 3.204 N/A GLN 129.A N SER 125.A O no hydrogen 3.201 N/A GLN 129.A NE2 GLU 73.A O no hydrogen 2.660 N/A MET 130.A N PHE 126.A O no hydrogen 3.115 N/A HIS 131.A N LEU 127.A O no hydrogen 2.796 N/A HIS 131.A ND1 TYR 250.A OH no hydrogen 2.871 N/A HIS 131.A NE2 ASP 226.A OD2 no hydrogen 2.468 N/A GLY 132.A N GLN 129.A O no hydrogen 3.304 N/A LEU 133.A N MET 130.A O no hydrogen 3.321 N/A THR 136.A N ASP 134.A OD1 no hydrogen 3.235 N/A THR 136.A OG1 ASP 134.A OD1 no hydrogen 3.072 N/A ILE 138.A N TYR 135.A O no hydrogen 3.264 N/A SER 139.A N THR 136.A O no hydrogen 3.129 N/A SER 139.A OG THR 136.A O no hydrogen 2.841 N/A GLU 140.A N GLU 140.A OE1 no hydrogen 3.311 N/A CYS 141.A N ILE 138.A O no hydrogen 2.849 N/A CYS 141.A SG GLU 140.A OE2 no hydrogen 3.427 N/A ILE 143.A N ILE 220.A O no hydrogen 2.835 N/A ASN 145.A ND2 TYR 261.A OH no hydrogen 2.882 N/A GLN 147.A N ASP 144.A OD1 no hydrogen 2.964 N/A ASN 148.A N ASP 144.A O no hydrogen 2.961 N/A VAL 149.A N ASN 145.A O no hydrogen 2.961 N/A LEU 150.A N LYS 146.A O no hydrogen 3.002 N/A GLU 151.A N GLN 147.A O no hydrogen 3.108 N/A GLU 152.A N ASN 148.A O no hydrogen 2.975 N/A TYR 153.A N VAL 149.A O no hydrogen 2.681 N/A TYR 153.A OH GLU 173.A OE2 no hydrogen 2.840 N/A ILE 154.A N LEU 150.A O no hydrogen 2.910 N/A LEU 155.A N GLU 151.A O no hydrogen 2.988 N/A LEU 156.A N GLU 152.A O no hydrogen 3.105 N/A ARG 157.A N TYR 153.A O no hydrogen 3.036 N/A ARG 157.A NH1 TYR 153.A OH no hydrogen 2.964 N/A GLU 158.A N ILE 154.A O no hydrogen 2.958 N/A THR 159.A N LEU 156.A O no hydrogen 2.984 N/A THR 159.A OG1 LEU 155.A O no hydrogen 2.777 N/A THR 159.A OG1 LEU 156.A O no hydrogen 3.455 N/A TYR 161.A N LEU 156.A O no hydrogen 2.896 N/A TYR 161.A OH GLU 173.A OE2 no hydrogen 2.860 N/A ASP 163.A N ILE 160.A O no hydrogen 3.130 N/A LEU 164.A N TYR 161.A O no hydrogen 3.001 N/A THR 165.A N GLU 168.A OE1 no hydrogen 2.596 N/A THR 165.A OG1 TYR 294.A OH no hydrogen 2.957 N/A GLU 168.A N THR 165.A O no hydrogen 3.102 N/A LYS 169.A N THR 165.A O no hydrogen 3.030 N/A ASP 170.A N ASP 166.A O no hydrogen 2.793 N/A TYR 171.A N ILE 167.A O no hydrogen 3.010 N/A TYR 171.A OH GLU 267.A O no hydrogen 3.045 N/A ILE 172.A N GLU 168.A O no hydrogen 3.003 N/A GLU 173.A N LYS 169.A O no hydrogen 2.766 N/A SER 174.A N ASP 170.A O no hydrogen 2.805 N/A PHE 175.A N TYR 171.A O no hydrogen 3.106 N/A MET 176.A N ILE 172.A O no hydrogen 2.954 N/A GLU 177.A N GLU 173.A O no hydrogen 3.145 N/A ARG 178.A N SER 174.A O no hydrogen 3.153 N/A ARG 178.A NH1 ASP 263.A OD2 no hydrogen 3.265 N/A ARG 178.A NH1 GLU 267.A OE1 no hydrogen 3.090 N/A ARG 178.A NH2 ASP 263.A OD2 no hydrogen 3.154 N/A LEU 179.A N PHE 175.A O no hydrogen 2.873 N/A ASN 180.A N MET 176.A O no hydrogen 3.175 N/A ASN 180.A N GLU 177.A O no hydrogen 3.316 N/A ALA 181.A N ARG 178.A O no hydrogen 2.910 N/A THR 182.A N ARG 178.A O no hydrogen 2.836 N/A THR 182.A OG1 GLU 260.A OE2 no hydrogen 2.798 N/A VAL 184.A N THR 182.A OG1 no hydrogen 3.266 N/A GLU 186.A N THR 183.A O no hydrogen 2.858 N/A LYS 189.A NZ PHE 185.A O no hydrogen 3.455 N/A LYS 189.A NZ ASP 222.A OD1 no hydrogen 2.685 N/A CYS 190.A N ILE 221.A O no hydrogen 2.762 N/A CYS 190.A SG LEU 191.A O no hydrogen 3.952 N/A CYS 192.A N GLY 219.A O no hydrogen 2.871 N/A CYS 192.A SG HIS 131.A NE2 no hydrogen 3.622 N/A CYS 192.A SG CYS 190.A O no hydrogen 3.803 N/A CYS 192.A SG ASP 222.A O no hydrogen 3.210 N/A HIS 193.A N ASP 226.A OD2 no hydrogen 3.011 N/A HIS 193.A NE2 ILE 213.A O no hydrogen 2.777 N/A ASN 194.A N ASP 226.A OD1 no hydrogen 2.707 N/A ASN 194.A ND2 ASP 217.A O no hydrogen 2.951 N/A ASP 195.A N HIS 193.A ND1 no hydrogen 3.032 N/A SER 197.A N ASP 195.A O no hydrogen 3.007 N/A SER 197.A OG ASP 195.A O no hydrogen 3.536 N/A SER 197.A OG ASN 199.A OD1 no hydrogen 2.422 N/A CYS 198.A N GLU 237.A OE1 no hydrogen 2.904 N/A CYS 198.A SG GLU 236.A O no hydrogen 4.034 N/A CYS 198.A SG GLU 237.A OE1 no hydrogen 3.439 N/A HIS 200.A N SER 197.A O no hydrogen 2.965 N/A HIS 200.A ND1 ASP 195.A O no hydrogen 2.714 N/A LEU 201.A N CYS 198.A O no hydrogen 2.733 N/A LEU 202.A N GLY 211.A O no hydrogen 2.691 N/A LEU 203.A N THR 101.A O no hydrogen 2.652 N/A ASP 204.A N ARG 208.A O no hydrogen 2.776 N/A ASN 206.A N ASP 204.A OD1 no hydrogen 2.768 N/A ASN 207.A N ASP 204.A O no hydrogen 2.910 N/A ASN 207.A ND2 GLU 115.A OE1 no hydrogen 3.378 N/A ARG 208.A N ASP 204.A OD1 no hydrogen 3.116 N/A ARG 208.A NE ASP 122.A OD1 no hydrogen 3.292 N/A ARG 208.A NE ASP 122.A OD2 no hydrogen 2.540 N/A ARG 208.A NH2 ASP 122.A OD1 no hydrogen 3.013 N/A THR 210.A N LEU 202.A O no hydrogen 2.824 N/A GLY 211.A N LEU 202.A O no hydrogen 3.146 N/A ILE 212.A N LYS 77.A O no hydrogen 3.012 N/A ILE 213.A N HIS 200.A O no hydrogen 3.092 N/A PHE 215.A N TYR 65.A OH no hydrogen 2.995 N/A GLY 216.A N ASP 214.A OD1 no hydrogen 3.081 N/A SER 218.A N PHE 215.A O no hydrogen 3.005 N/A SER 218.A OG HIS 193.A O no hydrogen 2.818 N/A SER 218.A OG PHE 215.A O no hydrogen 2.927 N/A GLY 219.A N CYS 192.A O no hydrogen 3.278 N/A ILE 220.A N CYS 141.A O no hydrogen 2.794 N/A ILE 221.A N CYS 190.A O no hydrogen 2.804 N/A GLU 223.A N LYS 188.A O no hydrogen 3.056 N/A CYS 225.A N ASP 222.A O no hydrogen 2.886 N/A CYS 225.A SG TYR 261.A OH no hydrogen 3.237 N/A PHE 227.A N TYR 224.A O no hydrogen 2.974 N/A ILE 228.A N CYS 225.A O no hydrogen 3.443 N/A LEU 231.A N PHE 227.A O no hydrogen 3.021 N/A GLU 232.A N TYR 229.A O no hydrogen 3.116 N/A SER 234.A OG GLU 232.A OE1 no hydrogen 2.429 N/A THR 240.A OG1 LEU 231.A O no hydrogen 2.744 N/A GLY 243.A N GLY 239.A O no hydrogen 3.329 N/A GLU 244.A N THR 240.A O no hydrogen 2.739 N/A ASP 245.A N ASN 241.A O no hydrogen 2.773 N/A ILE 246.A N PHE 242.A O no hydrogen 3.038 N/A LEU 247.A N GLY 243.A O no hydrogen 2.913 N/A ARG 248.A N GLU 244.A O no hydrogen 3.126 N/A MET 249.A N ASP 245.A O no hydrogen 3.028 N/A TYR 250.A N ILE 246.A O no hydrogen 2.894 N/A TYR 250.A OH HIS 131.A ND1 no hydrogen 2.871 N/A TYR 250.A OH GLU 223.A OE2 no hydrogen 2.520 N/A GLY 251.A N LEU 247.A O no hydrogen 3.021 N/A LYS 257.A N ASP 254.A OD1 no hydrogen 3.049 N/A ALA 258.A N ASP 254.A O no hydrogen 2.951 N/A LYS 259.A N ILE 255.A O no hydrogen 2.869 N/A GLU 260.A N GLU 256.A O no hydrogen 2.852 N/A TYR 261.A N LYS 257.A O no hydrogen 2.826 N/A TYR 261.A OH ASP 222.A OD2 no hydrogen 2.579 N/A GLN 262.A N ALA 258.A O no hydrogen 2.984 N/A GLN 262.A NE2 GLU 266.A OE1 no hydrogen 3.442 N/A ASP 263.A N LYS 259.A O no hydrogen 3.057 N/A ILE 264.A N GLU 260.A O no hydrogen 2.984 N/A VAL 265.A N TYR 261.A O no hydrogen 3.009 N/A GLU 266.A N GLN 262.A O no hydrogen 2.689 N/A GLU 267.A N ASP 263.A O no hydrogen 2.913 N/A TYR 268.A N ILE 264.A O no hydrogen 3.073 N/A TYR 268.A OH GLU 152.A OE1 no hydrogen 2.392 N/A TYR 269.A N VAL 265.A O no hydrogen 3.238 N/A TYR 269.A N GLU 266.A O no hydrogen 3.268 N/A GLU 272.A N TYR 268.A O no hydrogen 2.802 N/A THR 273.A N TYR 269.A O no hydrogen 2.871 N/A THR 273.A OG1 TYR 269.A O no hydrogen 2.794 N/A ILE 274.A N PRO 270.A O no hydrogen 3.085 N/A VAL 275.A N ILE 271.A O no hydrogen 2.744 N/A TYR 276.A N GLU 272.A O no hydrogen 2.809 N/A TYR 276.A OH TYR 33.A O no hydrogen 2.738 N/A GLY 277.A N THR 273.A O no hydrogen 2.886 N/A ILE 278.A N ILE 274.A O no hydrogen 2.919 N/A LYS 279.A N VAL 275.A O no hydrogen 2.842 N/A ASN 280.A N TYR 276.A O no hydrogen 3.211 N/A ASN 280.A ND2 TYR 276.A O no hydrogen 2.797 N/A LYS 282.A N GLY 277.A O no hydrogen 3.088 N/A LYS 282.A NZ ASN 280.A O no hydrogen 2.665 N/A GLU 284.A N GLU 284.A OE2 no hydrogen 2.727 N/A PHE 285.A N LYS 282.A O no hydrogen 2.821 N/A GLU 287.A N GLN 283.A O no hydrogen 3.002 N/A ASN 288.A N GLU 284.A O no hydrogen 3.236 N/A GLY 289.A N PHE 285.A O no hydrogen 2.982 N/A ARG 290.A N ILE 286.A O no hydrogen 2.831 N/A ARG 290.A NE GLU 168.A OE2 no hydrogen 2.543 N/A ARG 290.A NH2 GLU 168.A OE1 no hydrogen 2.518 N/A ARG 290.A NH2 GLU 168.A OE2 no hydrogen 2.997 N/A LYS 291.A N GLU 287.A O no hydrogen 2.798 N/A GLU 292.A N ASN 288.A O no hydrogen 2.639 N/A ILE 293.A N GLY 289.A O no hydrogen 3.051 N/A TYR 294.A OH THR 165.A OG1 no hydrogen 2.957 N/A LYS 295.A N LYS 291.A O no hydrogen 3.273 N/A LYS 295.A N GLU 292.A O no hydrogen 3.198 N/A LYS 295.A NZ GLU 292.A OE2 no hydrogen 2.386 N/A ARG 296.A N ILE 293.A O no hydrogen 3.074 N/A ARG 296.A NE GLU 292.A OE1 no hydrogen 3.153 N/A ARG 296.A NH2 GLU 266.A O no hydrogen 3.556 N/A THR 297.A N ILE 293.A O no hydrogen 3.119 N/A THR 297.A OG1 TYR 294.A O no hydrogen 3.487 N/A