Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4r3r_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ASN 5.A ND2 SER 72.A OG no hydrogen 2.968 N/A ALA 7.A N ASN 5.A OD1 no hydrogen 3.263 N/A ARG 10.A NH1 TYR 307.A OH no hydrogen 3.538 N/A ARG 10.A NH2 TYR 307.A OH no hydrogen 3.504 N/A LEU 12.A N ILE 84.A O no hydrogen 2.672 N/A LYS 13.A NZ GLU 16.A OE1 no hydrogen 3.044 N/A GLU 16.A N LYS 13.A O no hydrogen 3.008 N/A LYS 18.A N LEU 35.A O no hydrogen 2.803 N/A ILE 20.A N LYS 33.A O no hydrogen 2.746 N/A LYS 21.A N LYS 33.A O no hydrogen 3.040 N/A LEU 23.A N VAL 31.A O no hydrogen 2.932 N/A GLY 26.A N GLY 29.A O no hydrogen 2.847 N/A GLY 29.A N GLY 26.A O no hydrogen 2.886 N/A VAL 31.A N GLY 24.A O no hydrogen 2.860 N/A TYR 32.A N ILE 49.A O no hydrogen 2.541 N/A LYS 33.A N LYS 21.A O no hydrogen 2.690 N/A GLY 34.A N VAL 47.A O no hydrogen 3.084 N/A LEU 35.A N LYS 18.A O no hydrogen 2.853 N/A TRP 36.A N ILE 45.A O no hydrogen 2.634 N/A TRP 36.A NE1 GLU 16.A OE2 no hydrogen 3.303 N/A ILE 37.A N GLU 16.A O no hydrogen 2.724 N/A GLU 41.A N PRO 38.A O no hydrogen 3.158 N/A LYS 42.A NZ ASP 300.A OD1 no hydrogen 2.600 N/A LYS 44.A N ASP 300.A O no hydrogen 3.097 N/A ILE 45.A N TRP 36.A O no hydrogen 2.912 N/A VAL 47.A N GLY 34.A O no hydrogen 2.673 N/A ALA 48.A N THR 94.A O no hydrogen 2.956 N/A ILE 49.A N TYR 32.A O no hydrogen 2.740 N/A LYS 50.A N LEU 92.A O no hydrogen 3.198 N/A GLU 51.A N THR 30.A O no hydrogen 3.414 N/A ASN 60.A N SER 56.A O no hydrogen 3.064 N/A LYS 61.A N PRO 57.A O no hydrogen 3.004 N/A ILE 63.A N ALA 59.A O no hydrogen 3.257 N/A ILE 63.A N ASN 60.A O no hydrogen 3.276 N/A ALA 67.A N ILE 63.A O no hydrogen 3.381 N/A TYR 68.A N LEU 64.A O no hydrogen 2.784 N/A VAL 69.A N ASP 65.A O no hydrogen 2.513 N/A MET 70.A N GLU 66.A O no hydrogen 2.777 N/A ALA 71.A N ALA 67.A O no hydrogen 3.025 N/A SER 72.A N VAL 69.A O no hydrogen 2.968 N/A SER 72.A OG TYR 68.A O no hydrogen 2.737 N/A ASP 74.A N TYR 131.A OH no hydrogen 2.741 N/A HIS 77.A N ASN 75.A OD1 no hydrogen 2.765 N/A VAL 78.A N ASN 75.A O no hydrogen 2.977 N/A CYS 79.A N ILE 157.A O no hydrogen 3.132 N/A ARG 80.A NH1 VAL 73.A O no hydrogen 3.067 N/A LEU 82.A N ILE 93.A O no hydrogen 2.897 N/A GLY 83.A N ILE 93.A O no hydrogen 3.296 N/A ILE 84.A N ARG 10.A O no hydrogen 2.916 N/A CYS 85.A N GLN 91.A O no hydrogen 2.429 N/A CYS 85.A SG LEU 12.A O no hydrogen 3.075 N/A THR 87.A N CYS 85.A O no hydrogen 2.946 N/A THR 87.A OG1 THR 89.A O no hydrogen 2.356 N/A GLN 91.A N CYS 85.A O no hydrogen 2.263 N/A ILE 93.A N GLY 83.A O no hydrogen 2.866 N/A THR 94.A N ALA 48.A O no hydrogen 3.067 N/A THR 94.A OG1 ALA 48.A O no hydrogen 3.485 N/A GLN 95.A NE2 ASP 303.A OD1 no hydrogen 3.233 N/A GLN 95.A NE2 ASP 305.A OD2 no hydrogen 2.303 N/A LEU 96.A N PRO 46.A O no hydrogen 3.301 N/A GLY 100.A N MET 97.A O no hydrogen 2.823 N/A CYS 101.A SG ALA 144.A O no hydrogen 3.755 N/A CYS 101.A SG ARG 145.A O no hydrogen 3.272 N/A LEU 102.A N VAL 147.A O no hydrogen 2.870 N/A TYR 105.A N CYS 101.A O no hydrogen 3.113 N/A VAL 106.A N LEU 102.A O no hydrogen 3.104 N/A ARG 107.A NE GLY 215.A O no hydrogen 2.978 N/A ARG 107.A NH2 GLY 215.A O no hydrogen 3.089 N/A GLU 108.A N ASP 104.A O no hydrogen 2.941 N/A HIS 109.A N TYR 105.A O no hydrogen 2.747 N/A ASN 112.A N HIS 109.A O no hydrogen 3.026 N/A SER 115.A N ASP 288.A OD1 no hydrogen 2.966 N/A SER 115.A N ASP 288.A OD2 no hydrogen 3.270 N/A SER 115.A OG ASP 288.A OD1 no hydrogen 3.520 N/A SER 115.A OG ASP 288.A OD2 no hydrogen 3.009 N/A GLN 116.A NE2 GLN 116.A O no hydrogen 3.209 N/A GLN 116.A NE2 ASN 120.A OD1 no hydrogen 3.375 N/A GLN 116.A NE2 ALA 276.A O no hydrogen 3.072 N/A LEU 118.A N GLY 114.A O no hydrogen 3.488 N/A LEU 119.A N SER 115.A O no hydrogen 3.127 N/A ASN 120.A N GLN 116.A O no hydrogen 3.070 N/A TRP 121.A N TYR 117.A O no hydrogen 2.781 N/A TRP 121.A NE1 PRO 152.A O no hydrogen 2.755 N/A CYS 122.A N LEU 118.A O no hydrogen 3.150 N/A CYS 122.A SG LEU 118.A O no hydrogen 3.175 N/A VAL 123.A N LEU 119.A O no hydrogen 3.199 N/A GLN 124.A N ASN 120.A O no hydrogen 2.990 N/A GLN 124.A NE2 GLN 153.A O no hydrogen 2.722 N/A ILE 125.A N TRP 121.A O no hydrogen 3.071 N/A ALA 126.A N CYS 122.A O no hydrogen 3.126 N/A LYS 127.A N VAL 123.A O no hydrogen 2.792 N/A GLY 128.A N GLN 124.A O no hydrogen 2.891 N/A MET 129.A N ILE 125.A O no hydrogen 2.892 N/A ASN 130.A N ALA 126.A O no hydrogen 3.006 N/A TYR 131.A N LYS 127.A O no hydrogen 2.995 N/A LEU 132.A N GLY 128.A O no hydrogen 3.054 N/A GLU 133.A N MET 129.A O no hydrogen 2.911 N/A ASP 134.A N ASN 130.A O no hydrogen 3.077 N/A ARG 135.A N TYR 131.A O no hydrogen 3.093 N/A ARG 135.A NH1 SER 72.A O no hydrogen 2.454 N/A ARG 136.A N GLU 133.A O no hydrogen 2.939 N/A ARG 136.A NH1 GLY 167.A O no hydrogen 3.493 N/A ARG 136.A NH1 ALA 168.A O no hydrogen 3.496 N/A ARG 136.A NH2 GLY 167.A O no hydrogen 2.810 N/A LEU 137.A N LEU 132.A O no hydrogen 2.841 N/A VAL 138.A N LYS 164.A O no hydrogen 3.008 N/A HIS 139.A N ASP 200.A OD2 no hydrogen 2.876 N/A HIS 139.A NE2 THR 158.A O no hydrogen 2.671 N/A ARG 140.A N ASP 200.A OD1 no hydrogen 3.307 N/A ARG 140.A NH1 ARG 162.A O no hydrogen 2.464 N/A ASP 141.A N HIS 139.A ND1 no hydrogen 3.085 N/A ALA 144.A N GLU 210.A OE2 no hydrogen 3.248 N/A ASN 146.A N ALA 143.A O no hydrogen 2.900 N/A ASN 146.A ND2 ASP 141.A O no hydrogen 2.988 N/A LEU 148.A N LYS 156.A O no hydrogen 2.901 N/A VAL 149.A N GLY 100.A O no hydrogen 2.716 N/A LYS 150.A N HIS 154.A O no hydrogen 2.926 N/A LYS 150.A NZ ASP 303.A OD2 no hydrogen 2.796 N/A LYS 150.A NZ ASP 305.A OD2 no hydrogen 2.977 N/A THR 151.A N HIS 154.A O no hydrogen 3.198 N/A THR 151.A OG1 GLN 153.A OE1 no hydrogen 3.395 N/A GLN 153.A N THR 151.A OG1 no hydrogen 3.165 N/A HIS 154.A N THR 151.A O no hydrogen 2.834 N/A HIS 154.A NE2 PRO 76.A O no hydrogen 2.432 N/A VAL 155.A N GLN 124.A OE1 no hydrogen 2.987 N/A LYS 156.A N LEU 148.A O no hydrogen 2.989 N/A LYS 156.A NZ GLN 95.A OE1 no hydrogen 2.720 N/A LYS 156.A NZ ASP 305.A OD1 no hydrogen 2.501 N/A LYS 156.A NZ ASP 305.A OD2 no hydrogen 2.993 N/A ILE 157.A N HIS 77.A O no hydrogen 2.958 N/A THR 158.A N ASN 146.A O no hydrogen 3.124 N/A ASP 159.A N THR 158.A OG1 no hydrogen 2.505 N/A ARG 162.A NE ASP 141.A OD1 no hydrogen 3.519 N/A ARG 162.A NH2 ARG 140.A O no hydrogen 2.887 N/A ALA 163.A N PHE 160.A O no hydrogen 3.199 N/A LYS 164.A N VAL 138.A O no hydrogen 2.970 N/A LEU 166.A N ARG 136.A O no hydrogen 2.931 N/A GLY 167.A N GLU 170.A OE1 no hydrogen 2.362 N/A TYR 173.A N TYR 195.A O no hydrogen 2.997 N/A ALA 175.A N ARG 193.A O no hydrogen 3.222 N/A LYS 183.A NZ TYR 219.A O no hydrogen 2.983 N/A LYS 183.A NZ ILE 222.A O no hydrogen 2.875 N/A TRP 184.A N PRO 181.A O no hydrogen 3.135 N/A TRP 184.A NE1 GLU 210.A OE2 no hydrogen 2.765 N/A MET 185.A N ILE 182.A O no hydrogen 3.025 N/A GLU 188.A N GLU 188.A OE1 no hydrogen 2.593 N/A SER 189.A N ALA 186.A O no hydrogen 3.211 N/A SER 189.A OG ILE 194.A O no hydrogen 2.866 N/A ILE 190.A N ALA 186.A O no hydrogen 3.103 N/A LEU 191.A N LEU 187.A O no hydrogen 2.911 N/A HIS 192.A N GLU 188.A O no hydrogen 2.977 N/A ILE 194.A N GLU 188.A O no hydrogen 3.251 N/A TYR 195.A N TYR 173.A O no hydrogen 3.015 N/A THR 196.A N SER 199.A OG no hydrogen 2.686 N/A GLN 198.A NE2 ALA 259.A O no hydrogen 2.895 N/A GLN 198.A NE2 ARG 262.A O no hydrogen 3.109 N/A SER 199.A N THR 196.A O no hydrogen 3.017 N/A SER 199.A OG THR 196.A O no hydrogen 2.337 N/A ASP 200.A N THR 196.A O no hydrogen 3.294 N/A ASP 200.A N HIS 197.A O no hydrogen 3.196 N/A VAL 201.A N HIS 197.A O no hydrogen 3.228 N/A TRP 202.A N GLN 198.A O no hydrogen 3.202 N/A SER 203.A N SER 199.A O no hydrogen 3.329 N/A SER 203.A OG TRP 184.A O no hydrogen 2.838 N/A SER 203.A OG SER 199.A O no hydrogen 3.014 N/A TYR 204.A N ASP 200.A O no hydrogen 2.542 N/A TYR 204.A OH CYS 122.A O no hydrogen 2.644 N/A GLY 205.A N VAL 201.A O no hydrogen 2.875 N/A VAL 206.A N TRP 202.A O no hydrogen 3.200 N/A THR 207.A N SER 203.A O no hydrogen 3.156 N/A THR 207.A OG1 SER 203.A O no hydrogen 2.865 N/A VAL 208.A N TYR 204.A O no hydrogen 3.213 N/A TRP 209.A N GLY 205.A O no hydrogen 3.121 N/A TRP 209.A NE1 PRO 238.A O no hydrogen 2.510 N/A GLU 210.A N VAL 206.A O no hydrogen 2.935 N/A LEU 211.A N THR 207.A O no hydrogen 3.200 N/A MET 212.A N VAL 208.A O no hydrogen 2.874 N/A THR 213.A N TRP 209.A O no hydrogen 3.160 N/A THR 213.A N GLU 210.A O no hydrogen 3.294 N/A THR 213.A OG1 TRP 209.A O no hydrogen 2.731 N/A THR 213.A OG1 GLU 210.A O no hydrogen 3.045 N/A PHE 214.A N LEU 211.A O no hydrogen 2.925 N/A GLY 215.A N GLU 210.A O no hydrogen 2.699 N/A SER 216.A N THR 213.A OG1 no hydrogen 3.400 N/A SER 216.A OG THR 213.A O no hydrogen 3.087 N/A ILE 222.A N TYR 219.A O no hydrogen 3.370 N/A ILE 227.A N ALA 224.A O no hydrogen 3.282 N/A SER 228.A OG GLU 226.A OE1 no hydrogen 2.445 N/A SER 229.A OG GLU 226.A O no hydrogen 3.074 N/A LEU 231.A N ILE 227.A O no hydrogen 2.911 N/A GLU 232.A N SER 228.A O no hydrogen 3.196 N/A LYS 233.A N SER 229.A O no hydrogen 2.876 N/A GLY 234.A N LEU 231.A O no hydrogen 3.391 N/A GLU 235.A N ILE 230.A O no hydrogen 3.257 N/A ARG 236.A NE TRP 255.A O no hydrogen 2.840 N/A ARG 236.A NH1 TRP 255.A O no hydrogen 2.666 N/A ARG 236.A NH2 LEU 231.A O no hydrogen 2.896 N/A ARG 236.A NH2 GLU 235.A O no hydrogen 3.027 N/A GLN 239.A NE2 CYS 243.A O no hydrogen 2.612 N/A CYS 243.A N PRO 240.A O no hydrogen 2.980 N/A THR 244.A N TYR 282.A O no hydrogen 3.429 N/A THR 244.A OG1 TYR 282.A O no hydrogen 2.627 N/A TYR 248.A N THR 244.A O no hydrogen 3.130 N/A TYR 248.A OH LEU 237.A O no hydrogen 2.632 N/A MET 249.A N ILE 245.A O no hydrogen 2.631 N/A ILE 250.A N ASP 246.A O no hydrogen 3.382 N/A ILE 250.A N VAL 247.A O no hydrogen 3.036 N/A MET 251.A N VAL 247.A O no hydrogen 3.299 N/A VAL 252.A N TYR 248.A O no hydrogen 3.164 N/A LYS 253.A N MET 249.A O no hydrogen 3.289 N/A CYS 254.A N MET 251.A O no hydrogen 3.029 N/A CYS 254.A SG ILE 250.A O no hydrogen 3.446 N/A TRP 255.A N VAL 252.A O no hydrogen 2.856 N/A MET 256.A N LYS 253.A O no hydrogen 3.377 N/A SER 261.A N ASP 258.A O no hydrogen 2.801 N/A SER 261.A OG ASP 258.A OD2 no hydrogen 2.618 N/A ARG 262.A N ALA 259.A O no hydrogen 3.213 N/A ARG 262.A NE MET 256.A O no hydrogen 2.588 N/A ARG 262.A NH1 GLU 188.A OE2 no hydrogen 3.116 N/A ARG 262.A NH1 GLN 198.A O no hydrogen 3.029 N/A ARG 262.A NH2 GLU 188.A OE1 no hydrogen 3.198 N/A ARG 262.A NH2 MET 256.A O no hydrogen 2.880 N/A LYS 264.A NZ GLU 133.A OE1 no hydrogen 2.821 N/A LYS 264.A NZ GLN 198.A OE1 no hydrogen 2.696 N/A GLU 267.A N LYS 264.A O no hydrogen 3.112 N/A LEU 268.A N LYS 264.A O no hydrogen 3.217 N/A ILE 269.A N PHE 265.A O no hydrogen 3.155 N/A GLU 271.A N GLU 267.A O no hydrogen 3.032 N/A PHE 272.A N LEU 268.A O no hydrogen 3.149 N/A SER 273.A N ILE 269.A O no hydrogen 3.092 N/A SER 273.A OG ILE 269.A O no hydrogen 2.538 N/A SER 273.A OG ILE 270.A O no hydrogen 2.782 N/A LYS 274.A N ILE 270.A O no hydrogen 2.817 N/A MET 275.A N GLU 271.A O no hydrogen 3.075 N/A ALA 276.A N PHE 272.A O no hydrogen 2.760 N/A ASP 278.A N MET 275.A O no hydrogen 3.239 N/A ARG 281.A N ASP 278.A O no hydrogen 3.223 N/A TYR 282.A N PRO 279.A O no hydrogen 3.015 N/A LEU 283.A N PRO 279.A O no hydrogen 3.067 N/A VAL 284.A N ILE 242.A O no hydrogen 2.884 N/A ARG 290.A N GLY 287.A O no hydrogen 3.318 N/A HIS 292.A N ASN 112.A OD1 no hydrogen 2.745 N/A VAL 302.A N LYS 44.A O no hydrogen 2.832 N/A GLU 306.A N ASP 303.A O no hydrogen 2.885 N/A TYR 307.A N ALA 304.A O no hydrogen 3.126 N/A TYR 307.A OH GLU 41.A OE1 no hydrogen 3.217 N/A TYR 307.A OH GLU 41.A OE2 no hydrogen 2.309 N/A