Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4twf_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): VAL 2.A N GLN 129.A O no hydrogen 2.460 N/A VAL 4.A N ARG 131.A O no hydrogen 3.031 N/A SER 5.A N GLN 32.A O no hydrogen 2.615 N/A VAL 6.A N ASP 134.A O no hydrogen 3.448 N/A SER 7.A N VAL 30.A O no hydrogen 2.832 N/A ILE 8.A N GLN 136.A O no hydrogen 3.250 N/A PHE 9.A N TYR 28.A O no hydrogen 2.950 N/A ILE 10.A N TYR 138.A O no hydrogen 3.078 N/A ASN 11.A N ASP 26.A O no hydrogen 2.668 N/A LYS 12.A N ASP 26.A O no hydrogen 3.134 N/A TYR 14.A N LYS 24.A O no hydrogen 2.948 N/A ASN 17.A N THR 22.A O no hydrogen 2.518 N/A THR 18.A OG1 ARG 245.A O no hydrogen 3.129 N/A GLU 20.A N ASN 17.A OD1 no hydrogen 3.185 N/A THR 22.A N ASN 17.A O no hydrogen 3.256 N/A THR 22.A OG1 GLU 20.A O no hydrogen 3.478 N/A TYR 23.A N PHE 100.A O no hydrogen 2.981 N/A TYR 23.A OH VAL 117.A O no hydrogen 2.391 N/A LYS 24.A N TYR 14.A O no hydrogen 2.682 N/A VAL 25.A N GLY 98.A O no hydrogen 2.957 N/A ASP 26.A N LYS 12.A O no hydrogen 2.862 N/A GLY 27.A N PHE 96.A O no hydrogen 3.016 N/A TYR 28.A N PHE 9.A O no hydrogen 2.953 N/A ILE 29.A N ALA 94.A O no hydrogen 2.889 N/A VAL 30.A N SER 7.A O no hydrogen 2.827 N/A ALA 31.A N TYR 92.A O no hydrogen 2.892 N/A GLN 32.A N SER 5.A O no hydrogen 2.955 N/A TRP 33.A N VAL 90.A O no hydrogen 3.080 N/A GLY 35.A N GLY 88.A O no hydrogen 2.914 N/A ARG 38.A N PRO 86.A O no hydrogen 2.839 N/A THR 40.A OG1 PRO 41.A O no hydrogen 3.278 N/A THR 40.A OG1 LYS 44.A O no hydrogen 2.950 N/A LEU 46.A N LEU 84.A O no hydrogen 2.994 N/A VAL 48.A N LEU 82.A O no hydrogen 3.075 N/A ASN 50.A N LYS 80.A O no hydrogen 2.945 N/A ASN 50.A ND2 ASN 79.A OD1 no hydrogen 3.526 N/A GLN 52.A N GLU 49.A O no hydrogen 3.342 N/A ILE 53.A N ASN 50.A O no hydrogen 3.062 N/A ARG 55.A NH1 GLN 52.A OE1 no hydrogen 3.285 N/A TRP 56.A N GLN 52.A O no hydrogen 3.337 N/A ILE 57.A N ILE 53.A O no hydrogen 3.079 N/A ASN 58.A N GLU 54.A O no hydrogen 3.239 N/A GLY 60.A N ILE 57.A O no hydrogen 2.681 N/A LEU 61.A N ILE 57.A O no hydrogen 3.248 N/A GLU 67.A N GLU 121.A O no hydrogen 3.067 N/A ILE 69.A N GLU 119.A O no hydrogen 2.901 N/A ASN 70.A ND2 SER 101.A O no hydrogen 3.531 N/A ASN 70.A ND2 VAL 117.A O no hydrogen 2.446 N/A VAL 71.A N PHE 68.A O no hydrogen 3.327 N/A VAL 72.A N SER 99.A O no hydrogen 2.655 N/A ASP 76.A N LEU 97.A O no hydrogen 2.718 N/A GLY 78.A N ARG 95.A O no hydrogen 2.897 N/A LYS 80.A N ASN 50.A OD1 no hydrogen 3.241 N/A ARG 81.A N ASN 93.A O no hydrogen 2.744 N/A ARG 81.A NE ASN 93.A OD1 no hydrogen 2.695 N/A ARG 81.A NH2 ASN 93.A OD1 no hydrogen 2.750 N/A LEU 82.A N VAL 48.A O no hydrogen 2.778 N/A MET 83.A N ILE 91.A O no hydrogen 2.668 N/A LEU 84.A N LEU 46.A O no hydrogen 3.204 N/A PHE 85.A N ARG 89.A O no hydrogen 3.189 N/A ARG 89.A N ASP 87.A OD1 no hydrogen 3.450 N/A VAL 90.A N TRP 33.A O no hydrogen 2.776 N/A ILE 91.A N MET 83.A O no hydrogen 2.619 N/A TYR 92.A N ALA 31.A O no hydrogen 2.528 N/A ASN 93.A N ARG 81.A O no hydrogen 2.874 N/A ALA 94.A N ILE 29.A O no hydrogen 3.119 N/A ARG 95.A N ASN 79.A O no hydrogen 3.208 N/A ARG 95.A NE ASP 26.A OD2 no hydrogen 3.182 N/A ARG 95.A NH2 ASP 26.A OD1 no hydrogen 2.739 N/A ARG 95.A NH2 ASP 26.A OD2 no hydrogen 3.227 N/A PHE 96.A N GLY 27.A O no hydrogen 2.853 N/A LEU 97.A N ASP 76.A O no hydrogen 2.859 N/A GLY 98.A N VAL 25.A O no hydrogen 2.990 N/A PHE 100.A N TYR 23.A O no hydrogen 2.815 N/A SER 101.A N ASN 70.A O no hydrogen 2.724 N/A SER 101.A OG GLN 21.A O no hydrogen 3.012 N/A ASN 102.A ND2 GLN 115.A O no hydrogen 2.699 N/A PHE 106.A N TYR 248.A OH no hydrogen 2.835 N/A ARG 107.A N ASP 105.A OD1 no hydrogen 2.652 N/A ARG 107.A NE ASP 105.A OD1 no hydrogen 3.466 N/A ARG 107.A NE ASP 105.A OD2 no hydrogen 2.527 N/A ARG 107.A NH2 ASP 105.A OD2 no hydrogen 2.836 N/A PHE 109.A N PHE 106.A O no hydrogen 3.380 N/A PHE 111.A N LEU 108.A O no hydrogen 2.618 N/A ASP 112.A N ASP 112.A OD1 no hydrogen 2.443 N/A GLN 114.A N ALA 187.A O no hydrogen 2.870 N/A GLN 114.A NE2 ASP 105.A O no hydrogen 3.318 N/A PHE 116.A N ILE 185.A O no hydrogen 2.877 N/A VAL 117.A N TYR 23.A OH no hydrogen 2.406 N/A LEU 118.A N VAL 183.A O no hydrogen 2.900 N/A GLU 119.A N ASN 70.A OD1 no hydrogen 2.871 N/A LEU 120.A N ILE 181.A O no hydrogen 2.810 N/A GLU 121.A N GLU 67.A O no hydrogen 2.914 N/A PHE 123.A N ALA 65.A O no hydrogen 3.383 N/A ASN 127.A N GLU 177.A O no hydrogen 2.782 N/A ASN 127.A ND2 ASP 162.A OD2 no hydrogen 3.335 N/A GLN 128.A N GLU 177.A OE1 no hydrogen 2.659 N/A GLN 129.A N ASN 126.A O no hydrogen 3.168 N/A LEU 130.A N ASN 126.A O no hydrogen 3.103 N/A ARG 131.A N VAL 2.A O no hydrogen 2.951 N/A SER 133.A N VAL 4.A O no hydrogen 3.261 N/A SER 133.A OG VAL 4.A O no hydrogen 3.127 N/A TYR 138.A N ILE 8.A O no hydrogen 2.848 N/A ASN 141.A N THR 139.A O no hydrogen 2.588 N/A ASP 148.A N GLU 145.A O no hydrogen 3.197 N/A TRP 151.A N VAL 188.A O no hydrogen 2.703 N/A ARG 153.A N ASP 186.A O no hydrogen 3.106 N/A SER 157.A N ARG 184.A O no hydrogen 2.697 N/A HIS 159.A N THR 182.A O no hydrogen 3.014 N/A SER 161.A N ARG 180.A O no hydrogen 3.105 N/A ILE 163.A N PHE 178.A O no hydrogen 2.818 N/A TYR 165.A N ASN 176.A O no hydrogen 3.367 N/A TYR 165.A OH GLU 121.A OE1 no hydrogen 3.203 N/A TYR 165.A OH GLU 121.A OE2 no hydrogen 3.287 N/A SER 170.A OG SER 170.A O no hydrogen 2.201 N/A VAL 171.A N SER 169.A O no hydrogen 2.630 N/A ASN 174.A N GLN 175.A OE1 no hydrogen 3.223 N/A PHE 178.A N ILE 163.A O no hydrogen 2.948 N/A ARG 180.A N SER 161.A O no hydrogen 3.023 N/A ARG 180.A NE GLU 121.A OE1 no hydrogen 3.037 N/A ARG 180.A NH2 GLU 121.A OE1 no hydrogen 2.802 N/A ILE 181.A N LEU 120.A O no hydrogen 2.828 N/A THR 182.A N HIS 159.A O no hydrogen 3.087 N/A VAL 183.A N LEU 118.A O no hydrogen 2.733 N/A ARG 184.A N SER 157.A O no hydrogen 2.990 N/A ILE 185.A N PHE 116.A O no hydrogen 2.913 N/A ALA 187.A N GLN 114.A O no hydrogen 2.934 N/A VAL 188.A N TRP 151.A O no hydrogen 2.930 N/A ARG 189.A N ASP 112.A O no hydrogen 3.301 N/A ARG 189.A NE ASP 112.A OD1 no hydrogen 2.788 N/A ARG 189.A NE ASP 112.A OD2 no hydrogen 2.995 N/A ARG 189.A NH2 ASP 112.A OD2 no hydrogen 3.034 N/A ASN 190.A N GLU 149.A O no hydrogen 3.318 N/A SER 192.A N ASN 190.A OD1 no hydrogen 3.243 N/A SER 192.A OG ASN 190.A OD1 no hydrogen 3.046 N/A LEU 195.A N PRO 191.A O no hydrogen 2.926 N/A TRP 196.A N SER 192.A O no hydrogen 3.205 N/A SER 197.A N TYR 193.A O no hydrogen 2.925 N/A PHE 198.A N TYR 194.A O no hydrogen 3.282 N/A ILE 199.A N TYR 194.A O no hydrogen 3.078 N/A LEU 200.A N LEU 195.A O no hydrogen 3.021 N/A LEU 202.A N PHE 198.A O no hydrogen 3.157 N/A GLY 203.A N ILE 199.A O no hydrogen 2.950 N/A LEU 204.A N LEU 200.A O no hydrogen 3.200 N/A ILE 205.A N PRO 201.A O no hydrogen 3.072 N/A ILE 206.A N LEU 202.A O no hydrogen 3.023 N/A ALA 207.A N GLY 203.A O no hydrogen 2.638 N/A ALA 208.A N LEU 204.A O no hydrogen 2.709 N/A SER 209.A N ILE 205.A O no hydrogen 2.455 N/A TRP 210.A N ALA 207.A O no hydrogen 2.799 N/A TRP 210.A NE1 SER 262.A OG no hydrogen 2.681 N/A SER 211.A N ALA 208.A O no hydrogen 3.003 N/A SER 211.A OG ALA 208.A O no hydrogen 2.165 N/A PHE 213.A N TRP 210.A O no hydrogen 3.379 N/A LEU 215.A N VAL 212.A O no hydrogen 3.123 N/A SER 219.A N SER 217.A OG no hydrogen 3.083 N/A ARG 221.A N SER 217.A O no hydrogen 3.237 N/A ARG 221.A NH1 GLU 216.A O no hydrogen 3.469 N/A LEU 222.A N PHE 218.A O no hydrogen 2.678 N/A GLN 223.A N SER 219.A O no hydrogen 2.545 N/A THR 224.A N GLU 220.A O no hydrogen 3.001 N/A THR 224.A OG1 GLU 220.A O no hydrogen 2.900 N/A SER 225.A OG ARG 221.A O no hydrogen 3.323 N/A SER 225.A OG LEU 222.A O no hydrogen 2.178 N/A PHE 226.A N GLN 223.A O no hydrogen 3.353 N/A THR 227.A N THR 224.A O no hydrogen 2.713 N/A LEU 230.A N PHE 226.A O no hydrogen 3.187 N/A THR 231.A N THR 227.A O no hydrogen 2.981 N/A THR 231.A OG1 THR 227.A O no hydrogen 2.921 N/A VAL 232.A N LEU 228.A O no hydrogen 2.983 N/A VAL 233.A N MET 229.A O no hydrogen 2.964 N/A ALA 234.A N LEU 230.A O no hydrogen 2.813 N/A TYR 235.A N THR 231.A O no hydrogen 2.996 N/A ALA 236.A N VAL 232.A O no hydrogen 2.966 N/A SER 237.A N VAL 233.A O no hydrogen 3.235 N/A SER 237.A OG ALA 234.A O no hydrogen 2.895 N/A TYR 238.A N ALA 234.A O no hydrogen 3.321 N/A TYR 238.A OH SER 197.A O no hydrogen 3.058 N/A THR 239.A N TYR 235.A O no hydrogen 2.960 N/A THR 239.A OG1 TYR 235.A O no hydrogen 3.174 N/A SER 240.A N ALA 236.A O no hydrogen 2.749 N/A SER 240.A OG ALA 236.A O no hydrogen 3.056 N/A SER 240.A OG SER 237.A O no hydrogen 3.104 N/A ASN 241.A N SER 237.A O no hydrogen 2.895 N/A ILE 242.A N THR 239.A O no hydrogen 3.243 N/A LEU 243.A N THR 239.A O no hydrogen 2.836 N/A THR 250.A N ASP 253.A OD2 no hydrogen 2.333 N/A VAL 251.A N PHE 109.A O no hydrogen 3.235 N/A ASP 253.A N THR 250.A OG1 no hydrogen 3.209 N/A MET 255.A N VAL 251.A O no hydrogen 3.096 N/A ILE 256.A N ILE 252.A O no hydrogen 2.988 N/A ILE 257.A N ASP 253.A O no hydrogen 2.862 N/A ALA 258.A N GLN 254.A O no hydrogen 2.797 N/A GLY 259.A N MET 255.A O no hydrogen 2.848 N/A TYR 260.A N ILE 256.A O no hydrogen 2.859 N/A GLY 261.A N ILE 257.A O no hydrogen 2.772 N/A SER 262.A N ALA 258.A O no hydrogen 2.737 N/A ILE 263.A N GLY 259.A O no hydrogen 3.302 N/A PHE 264.A N TYR 260.A O no hydrogen 2.949 N/A ALA 265.A N GLY 261.A O no hydrogen 3.025 N/A ALA 266.A N SER 262.A O no hydrogen 3.383 N/A ILE 267.A N ILE 263.A O no hydrogen 2.935 N/A LEU 268.A N PHE 264.A O no hydrogen 3.101 N/A LEU 269.A N ALA 265.A O no hydrogen 2.912 N/A ILE 270.A N ALA 266.A O no hydrogen 2.950 N/A ILE 271.A N ILE 267.A O no hydrogen 3.255 N/A PHE 272.A N LEU 268.A O no hydrogen 2.702 N/A ALA 273.A N LEU 269.A O no hydrogen 2.540 N/A HIS 274.A N ILE 271.A O no hydrogen 3.218 N/A HIS 275.A N ILE 271.A O no hydrogen 3.317 N/A ALA 278.A N GLU 282.A OE1 no hydrogen 2.438 N/A GLY 280.A N ASN 279.A OD1 no hydrogen 2.274 N/A GLU 282.A N ASN 279.A OD1 no hydrogen 2.644 N/A LEU 286.A N ASP 284.A OD1 no hydrogen 2.969 N/A ILE 287.A N ASP 284.A O no hydrogen 3.000 N/A GLN 288.A N ASP 284.A O no hydrogen 3.475 N/A ARG 289.A NE LEU 286.A O no hydrogen 3.530 N/A CYS 290.A N ILE 287.A O no hydrogen 3.078 N/A CYS 290.A SG ILE 287.A O no hydrogen 2.946 N/A ALA 293.A N CYS 290.A O no hydrogen 3.260 N/A PHE 298.A N PHE 294.A O no hydrogen 2.837 N/A LEU 299.A N PRO 295.A O no hydrogen 2.989 N/A ALA 300.A N LEU 296.A O no hydrogen 2.620 N/A ILE 301.A N GLY 297.A O no hydrogen 3.418 N/A GLY 302.A N PHE 298.A O no hydrogen 2.902 N/A CYS 303.A N LEU 299.A O no hydrogen 2.877 N/A CYS 303.A SG LEU 299.A O no hydrogen 3.083 N/A VAL 304.A N ALA 300.A O no hydrogen 2.844 N/A LEU 305.A N ILE 301.A O no hydrogen 2.639 N/A ILE 307.A N VAL 304.A O no hydrogen 2.944 N/A