Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4u81_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LYS 4.A NZ ASP 6.A OD1 no hydrogen 2.804 N/A LYS 4.A NZ ASP 7.A OD1 no hydrogen 3.221 N/A ASP 7.A N LYS 4.A O no hydrogen 3.236 N/A GLU 9.A N SER 26.A O no hydrogen 3.008 N/A ILE 11.A N LYS 24.A O no hydrogen 2.869 N/A SER 12.A N LYS 24.A O no hydrogen 3.284 N/A LEU 14.A N VAL 22.A O no hydrogen 2.999 N/A GLY 17.A N GLY 20.A O no hydrogen 2.961 N/A GLY 20.A N GLY 17.A O no hydrogen 3.271 N/A VAL 21.A N LEU 38.A O no hydrogen 3.127 N/A VAL 22.A N GLY 15.A O no hydrogen 3.060 N/A PHE 23.A N ARG 36.A O no hydrogen 2.810 N/A LYS 24.A N SER 12.A O no hydrogen 2.937 N/A VAL 25.A N MET 34.A O no hydrogen 2.867 N/A SER 26.A N GLU 9.A O no hydrogen 2.915 N/A HIS 27.A N LEU 32.A O no hydrogen 2.959 N/A HIS 27.A ND1 SER 30.A OG no hydrogen 2.652 N/A LYS 28.A N ASP 7.A O no hydrogen 2.915 N/A SER 30.A N HIS 27.A O no hydrogen 3.175 N/A SER 30.A OG HIS 27.A ND1 no hydrogen 2.652 N/A SER 30.A OG HIS 27.A O no hydrogen 3.306 N/A GLY 31.A N HIS 27.A O no hydrogen 2.829 N/A LEU 32.A N SER 30.A OG no hydrogen 3.154 N/A MET 34.A N VAL 25.A O no hydrogen 2.814 N/A ALA 35.A N MET 83.A O no hydrogen 2.795 N/A ARG 36.A N PHE 23.A O no hydrogen 2.760 N/A ARG 36.A NE SER 80.A OG no hydrogen 2.915 N/A ARG 36.A NH1 ASP 5.A OD1 no hydrogen 3.292 N/A ARG 36.A NH2 ASP 5.A OD1 no hydrogen 2.861 N/A ARG 36.A NH2 SER 80.A OG no hydrogen 3.186 N/A LYS 37.A N ILE 81.A O no hydrogen 2.862 N/A LYS 37.A NZ ASP 148.A OD1 no hydrogen 3.059 N/A LYS 37.A NZ ASP 148.A OD2 no hydrogen 2.906 N/A LEU 38.A N VAL 21.A O no hydrogen 2.763 N/A ILE 39.A N ILE 79.A O no hydrogen 2.765 N/A HIS 40.A ND1 GLU 78.A OE2 no hydrogen 3.084 N/A LEU 41.A N GLY 77.A O no hydrogen 2.860 N/A ARG 48.A N LYS 44.A O no hydrogen 3.221 N/A ASN 49.A N PRO 45.A O no hydrogen 3.313 N/A GLN 50.A N ILE 47.A O no hydrogen 3.184 N/A GLN 50.A NE2 GLU 54.A OE2 no hydrogen 3.025 N/A ILE 51.A N ILE 47.A O no hydrogen 2.997 N/A ILE 52.A N ARG 48.A O no hydrogen 2.956 N/A ARG 53.A N ASN 49.A O no hydrogen 2.944 N/A GLU 54.A N GLN 50.A O no hydrogen 2.705 N/A LEU 55.A N ILE 51.A O no hydrogen 2.891 N/A GLN 56.A N ILE 52.A O no hydrogen 3.318 N/A GLN 56.A NE2 ILE 52.A O no hydrogen 3.141 N/A LEU 58.A N LEU 55.A O no hydrogen 2.794 N/A HIS 59.A N GLN 56.A O no hydrogen 3.052 N/A HIS 59.A NE2 TYR 70.A O no hydrogen 3.164 N/A GLU 60.A N VAL 57.A O no hydrogen 2.847 N/A CYS 61.A N LEU 58.A O no hydrogen 3.020 N/A CYS 61.A SG VAL 57.A O no hydrogen 3.549 N/A ASN 62.A N TYR 119.A OH no hydrogen 2.870 N/A ASN 62.A ND2 HIS 59.A O no hydrogen 3.217 N/A TYR 65.A N SER 63.A OG no hydrogen 3.099 N/A ILE 66.A N SER 63.A O no hydrogen 3.155 N/A VAL 67.A N LEU 146.A O no hydrogen 2.924 N/A GLY 68.A N GLU 84.A OE2 no hydrogen 3.185 N/A TYR 70.A N CYS 82.A O no hydrogen 2.870 N/A GLY 71.A N CYS 82.A O no hydrogen 3.362 N/A PHE 73.A N SER 80.A O no hydrogen 2.996 N/A SER 75.A N GLU 78.A O no hydrogen 2.952 N/A GLY 77.A N TYR 74.A OH no hydrogen 2.724 N/A ILE 79.A N ILE 39.A O no hydrogen 2.896 N/A SER 80.A N PHE 73.A O no hydrogen 2.736 N/A ILE 81.A N LYS 37.A O no hydrogen 2.914 N/A CYS 82.A N GLY 71.A O no hydrogen 2.745 N/A MET 83.A N ALA 35.A O no hydrogen 2.811 N/A GLU 84.A N GLY 68.A O no hydrogen 2.958 N/A GLY 88.A N VAL 138.A O no hydrogen 2.873 N/A GLY 89.A N MET 86.A O no hydrogen 3.043 N/A SER 90.A N GLN 93.A OE1 no hydrogen 3.296 N/A SER 90.A OG ASP 92.A OD2 no hydrogen 2.298 N/A LEU 91.A N PRO 133.A O no hydrogen 3.008 N/A LEU 91.A N ILE 136.A O no hydrogen 2.951 N/A VAL 94.A N SER 90.A O no hydrogen 3.275 N/A LEU 95.A N LEU 91.A O no hydrogen 2.857 N/A LYS 96.A N ASP 92.A O no hydrogen 3.229 N/A LYS 97.A N GLN 93.A O no hydrogen 3.432 N/A ALA 98.A N VAL 94.A O no hydrogen 2.806 N/A GLY 99.A N LEU 95.A O no hydrogen 2.853 N/A ARG 100.A NH1 MET 211.A O no hydrogen 2.819 N/A ILE 101.A N MET 193.A O no hydrogen 2.940 N/A LEU 106.A N PRO 102.A O no hydrogen 2.979 N/A GLY 107.A N GLN 104.A O no hydrogen 3.110 N/A LYS 108.A N GLN 104.A O no hydrogen 3.405 N/A LYS 108.A NZ SER 271.A O no hydrogen 2.509 N/A LYS 108.A NZ GLU 274.A O no hydrogen 2.791 N/A VAL 109.A N ILE 105.A O no hydrogen 3.037 N/A SER 110.A N LEU 106.A O no hydrogen 2.942 N/A SER 110.A OG LEU 106.A O no hydrogen 2.501 N/A ILE 111.A N GLY 107.A O no hydrogen 3.151 N/A ALA 112.A N LYS 108.A O no hydrogen 3.055 N/A VAL 113.A N VAL 109.A O no hydrogen 2.844 N/A ILE 114.A N SER 110.A O no hydrogen 2.979 N/A LYS 115.A N ILE 111.A O no hydrogen 2.940 N/A GLY 116.A N ALA 112.A O no hydrogen 2.883 N/A LEU 117.A N VAL 113.A O no hydrogen 2.880 N/A THR 118.A N ILE 114.A O no hydrogen 2.962 N/A THR 118.A OG1 ILE 114.A O no hydrogen 2.499 N/A TYR 119.A N LYS 115.A O no hydrogen 2.807 N/A LEU 120.A N GLY 116.A O no hydrogen 3.026 N/A ARG 121.A N LEU 117.A O no hydrogen 2.794 N/A GLU 122.A N THR 118.A O no hydrogen 2.700 N/A LYS 123.A N TYR 119.A O no hydrogen 2.863 N/A HIS 124.A N LEU 120.A O no hydrogen 3.096 N/A HIS 124.A NE2 TYR 119.A OH no hydrogen 3.168 N/A LYS 125.A N ARG 121.A O no hydrogen 2.961 N/A ILE 126.A N LEU 120.A O no hydrogen 2.996 N/A HIS 128.A N ASP 182.A OD2 no hydrogen 2.712 N/A ARG 129.A N ASP 182.A OD1 no hydrogen 2.999 N/A ASP 130.A N HIS 128.A ND1 no hydrogen 3.130 N/A ASN 135.A N LYS 132.A O no hydrogen 3.007 N/A ASN 135.A ND2 ASP 130.A O no hydrogen 2.750 N/A ILE 136.A N PRO 133.A O no hydrogen 3.281 N/A LEU 137.A N LYS 145.A O no hydrogen 2.813 N/A VAL 138.A N GLY 89.A O no hydrogen 2.818 N/A ASN 139.A N GLU 143.A O no hydrogen 3.202 N/A ASN 139.A ND2 GLU 143.A OE2 no hydrogen 2.825 N/A SER 140.A N ASP 87.A OD2 no hydrogen 2.839 N/A SER 140.A OG ASP 87.A OD1 no hydrogen 2.620 N/A SER 140.A OG ASP 87.A OD2 no hydrogen 3.307 N/A ARG 141.A N ASN 139.A OD1 no hydrogen 3.108 N/A GLY 142.A N ASN 139.A O no hydrogen 2.859 N/A GLU 143.A N ASN 139.A OD1 no hydrogen 3.026 N/A LYS 145.A N LEU 137.A O no hydrogen 2.891 N/A LYS 145.A NZ GLU 84.A OE1 no hydrogen 2.902 N/A LYS 145.A NZ GLU 84.A OE2 no hydrogen 2.658 N/A LEU 146.A N TYR 65.A O no hydrogen 2.863 N/A CYS 147.A N ASN 135.A O no hydrogen 3.203 N/A CYS 147.A SG ASN 135.A O no hydrogen 3.598 N/A GLY 150.A N HIS 128.A O no hydrogen 3.038 N/A VAL 151.A N PHE 149.A O no hydrogen 3.022 N/A SER 152.A OG GLU 54.A OE1 no hydrogen 2.499 N/A GLN 154.A N GLU 54.A OE1 no hydrogen 2.920 N/A GLN 154.A NE2 SER 158.A OG no hydrogen 2.908 N/A LEU 155.A N SER 152.A OG no hydrogen 3.031 N/A ILE 156.A N SER 152.A O no hydrogen 3.215 N/A ASP 157.A N GLY 153.A O no hydrogen 3.096 N/A SER 158.A N GLN 154.A O no hydrogen 2.905 N/A SER 158.A OG GLN 154.A O no hydrogen 3.128 N/A MET 159.A N ILE 156.A O no hydrogen 2.964 N/A ALA 160.A N ILE 156.A O no hydrogen 3.102 N/A ALA 160.A N ASP 157.A O no hydrogen 3.287 N/A TYR 166.A OH GLU 192.A OE2 no hydrogen 2.757 N/A SER 168.A OG SER 181.A OG no hydrogen 2.454 N/A GLU 170.A N GLU 170.A OE1 no hydrogen 2.894 N/A ARG 171.A N SER 168.A OG no hydrogen 3.216 N/A ARG 171.A NH1 ARG 129.A O no hydrogen 2.733 N/A LEU 172.A N SER 168.A O no hydrogen 3.058 N/A GLN 173.A N PRO 169.A O no hydrogen 3.112 N/A GLN 173.A N GLU 170.A O no hydrogen 3.277 N/A GLN 173.A NE2 PRO 169.A O no hydrogen 3.131 N/A TYR 177.A N THR 175.A O no hydrogen 2.768 N/A VAL 179.A N SER 178.A OG no hydrogen 2.452 N/A GLN 180.A NE2 PRO 253.A O no hydrogen 3.019 N/A GLN 180.A NE2 ALA 257.A O no hydrogen 2.839 N/A SER 181.A N SER 178.A O no hydrogen 2.931 N/A SER 181.A OG SER 168.A OG no hydrogen 2.454 N/A ASP 182.A N VAL 179.A O no hydrogen 3.034 N/A ILE 183.A N GLN 180.A O no hydrogen 2.817 N/A SER 185.A N SER 181.A O no hydrogen 3.312 N/A SER 185.A OG TYR 166.A O no hydrogen 2.511 N/A SER 185.A OG SER 181.A O no hydrogen 3.462 N/A MET 186.A N ASP 182.A O no hydrogen 2.953 N/A GLY 187.A N ILE 183.A O no hydrogen 2.887 N/A LEU 188.A N TRP 184.A O no hydrogen 2.864 N/A SER 189.A N SER 185.A O no hydrogen 2.866 N/A SER 189.A OG SER 185.A O no hydrogen 2.881 N/A LEU 190.A N MET 186.A O no hydrogen 2.890 N/A LEU 190.A N GLY 187.A O no hydrogen 3.091 N/A VAL 191.A N GLY 187.A O no hydrogen 3.192 N/A MET 193.A N SER 189.A O no hydrogen 3.361 N/A ALA 194.A N LEU 190.A O no hydrogen 2.846 N/A GLY 196.A N GLU 192.A O no hydrogen 2.601 N/A ARG 197.A NH1 TYR 198.A O no hydrogen 3.229 N/A ARG 197.A NH1 PRO 201.A O no hydrogen 2.549 N/A ARG 197.A NH2 GLU 207.A OE2 no hydrogen 2.223 N/A TYR 198.A OH SER 165.A O no hydrogen 2.530 N/A LEU 208.A N ASP 204.A O no hydrogen 3.042 N/A GLU 209.A N ALA 205.A O no hydrogen 3.185 N/A LEU 210.A N LYS 206.A O no hydrogen 3.318 N/A MET 211.A N GLU 207.A O no hydrogen 3.351 N/A PHE 212.A N LEU 208.A O no hydrogen 2.819 N/A LEU 220.A N ALA 216.A O no hydrogen 2.951 N/A LEU 220.A N ILE 217.A O no hydrogen 3.227 N/A LEU 221.A N ILE 217.A O no hydrogen 3.010 N/A ASP 222.A N PHE 218.A O no hydrogen 2.717 N/A TYR 223.A N GLU 219.A O no hydrogen 3.135 N/A ILE 224.A N LEU 220.A O no hydrogen 3.089 N/A VAL 225.A N LEU 221.A O no hydrogen 3.075 N/A ASN 226.A N ASP 222.A O no hydrogen 3.082 N/A ASN 226.A N TYR 223.A O no hydrogen 3.227 N/A ASN 226.A ND2 ASP 222.A OD1 no hydrogen 2.952 N/A GLU 227.A N TYR 223.A O no hydrogen 2.822 N/A SER 238.A N GLU 103.A OE1 no hydrogen 3.266 N/A SER 238.A OG GLU 103.A OE2 no hydrogen 2.687 N/A GLU 240.A N GLU 240.A OE1 no hydrogen 2.970 N/A PHE 241.A N SER 238.A OG no hydrogen 3.071 N/A GLN 242.A N SER 238.A O no hydrogen 3.168 N/A GLN 242.A NE2 PHE 237.A O no hydrogen 2.939 N/A ASP 243.A N LEU 239.A O no hydrogen 2.919 N/A PHE 244.A N GLU 240.A O no hydrogen 2.885 N/A VAL 245.A N PHE 241.A O no hydrogen 3.077 N/A ASN 246.A N GLN 242.A O no hydrogen 2.993 N/A LYS 247.A N ASP 243.A O no hydrogen 2.879 N/A LYS 247.A NZ ASP 243.A OD1 no hydrogen 3.173 N/A LYS 247.A NZ ASP 243.A OD2 no hydrogen 2.563 N/A CYS 248.A N PHE 244.A O no hydrogen 3.307 N/A CYS 248.A N VAL 245.A O no hydrogen 2.869 N/A CYS 248.A SG PHE 244.A O no hydrogen 3.324 N/A LEU 249.A N ASN 246.A O no hydrogen 3.377 N/A LYS 251.A NZ VAL 225.A O no hydrogen 3.012 N/A LYS 251.A NZ GLU 227.A O no hydrogen 2.735 N/A ALA 254.A N ASN 252.A OD1 no hydrogen 2.819 N/A GLU 255.A N ASN 252.A O no hydrogen 3.073 N/A GLU 255.A N ASN 252.A OD1 no hydrogen 3.110 N/A ARG 256.A N ASN 252.A O no hydrogen 2.874 N/A ARG 256.A NE GLN 180.A O no hydrogen 3.564 N/A ARG 256.A NH1 GLU 170.A OE1 no hydrogen 3.489 N/A ARG 256.A NH1 ILE 250.A O no hydrogen 2.658 N/A ARG 256.A NH1 LYS 251.A O no hydrogen 3.134 N/A ARG 256.A NH2 GLU 170.A OE1 no hydrogen 3.135 N/A ARG 256.A NH2 GLU 170.A OE2 no hydrogen 2.422 N/A ALA 257.A N LYS 247.A O no hydrogen 3.076 N/A ASP 258.A N GLN 261.A OE1 no hydrogen 3.423 N/A GLN 261.A N ASP 258.A OD1 no hydrogen 3.221 N/A LEU 262.A N ASP 258.A O no hydrogen 3.018 N/A MET 263.A N LEU 259.A O no hydrogen 2.959 N/A VAL 264.A N GLN 261.A O no hydrogen 3.136 N/A HIS 265.A N LEU 262.A O no hydrogen 3.160 N/A HIS 265.A NE2 ASP 243.A OD2 no hydrogen 2.787 N/A PHE 267.A N HIS 265.A ND1 no hydrogen 2.922 N/A ILE 268.A N HIS 265.A O no hydrogen 3.017 N/A LYS 269.A N HIS 265.A O no hydrogen 3.100 N/A ARG 270.A N ALA 266.A O no hydrogen 2.962 N/A ARG 270.A NE GLU 274.A OE2 no hydrogen 2.910 N/A ARG 270.A NH1 SER 238.A OG no hydrogen 2.840 N/A ARG 270.A NH2 GLU 103.A OE2 no hydrogen 2.757 N/A SER 271.A N PHE 267.A O no hydrogen 2.959 N/A SER 271.A OG PHE 267.A O no hydrogen 2.785 N/A ASP 272.A N ILE 268.A O no hydrogen 2.648 N/A ALA 273.A N LYS 269.A O no hydrogen 3.352 N/A GLU 274.A N ARG 270.A O no hydrogen 3.290 N/A GLY 280.A N ASP 277.A OD1 no hydrogen 3.032 N/A TRP 281.A N ASP 277.A O no hydrogen 2.875 N/A LEU 282.A N PHE 278.A O no hydrogen 2.789 N/A CYS 283.A N ALA 279.A O no hydrogen 3.106 N/A CYS 283.A SG ALA 279.A O no hydrogen 3.220 N/A SER 284.A N GLY 280.A O no hydrogen 3.063 N/A SER 284.A OG GLY 280.A O no hydrogen 3.004 N/A THR 285.A N TRP 281.A O no hydrogen 3.116 N/A ILE 286.A N LEU 282.A O no hydrogen 3.072 N/A LEU 288.A N CYS 283.A O no hydrogen 3.172 N/A