Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4wv8_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): GLU 3.A N LEU 233.A O no hydrogen 3.019 N/A VAL 5.A N.A SER 231.A O no hydrogen 2.990 N/A VAL 5.A N.B SER 231.A O no hydrogen 2.985 N/A SER 6.A OG.A THR 230.A OG1 no hydrogen 2.699 N/A SER 6.A OG.B PHE 229.A O no hydrogen 3.158 N/A PHE 7.A N PHE 229.A O no hydrogen 2.877 N/A SER 8.A OG.A SER 228.A OG.A no hydrogen 2.965 N/A PHE 9.A N TRP 227.A O no hydrogen 2.891 N/A PHE 12.A N GLY 31.A O no hydrogen 3.057 N/A ILE 19.A N PRO 16.A O no hydrogen 3.160 N/A ILE 20.A N LEU 52.A O no hydrogen 2.774 N/A GLN 22.A N ARG 50.A O no hydrogen 2.881 N/A GLN 22.A NE2 THR 99.A O no hydrogen 3.033 N/A ASP 24.A N LEU 48.A O no hydrogen 2.810 N/A ALA 25.A N GLN 22.A O no hydrogen 3.247 N/A LEU 26.A N GLN 34.A O no hydrogen 3.085 N/A THR 28.A N LYS 32.A O no hydrogen 2.849 N/A LYS 30.A N THR 28.A OG1 no hydrogen 3.229 N/A GLY 31.A N THR 28.A O no hydrogen 2.930 N/A LYS 32.A N THR 28.A OG1 no hydrogen 3.054 N/A LYS 32.A NZ ASP 223.A OD2 no hydrogen 3.395 N/A LEU 33.A N VAL 224.A O no hydrogen 2.948 N/A GLN 34.A N LEU 26.A O no hydrogen 2.814 N/A LEU 35.A N HIS 222.A O no hydrogen 3.038 N/A THR 36.A OG1 HIS 222.A ND1 no hydrogen 2.822 N/A LYS 37.A N SER 47.A OG no hydrogen 2.941 N/A LYS 39.A N LYS 42.A O no hydrogen 2.860 N/A LYS 42.A N LYS 39.A O no hydrogen 2.865 N/A VAL 44.A N LYS 37.A O no hydrogen 2.949 N/A HIS 46.A N GLY 213.A O no hydrogen 2.862 N/A HIS 46.A ND1 ASP 45.A OD2 no hydrogen 2.641 N/A SER 47.A N SER 212.A OG no hydrogen 3.030 N/A SER 47.A OG ASP 24.A OD2 no hydrogen 2.646 N/A LEU 48.A N ASP 24.A OD2 no hydrogen 3.255 N/A GLY 49.A N ALA 210.A O no hydrogen 3.052 N/A ARG 50.A N GLN 22.A O no hydrogen 3.034 N/A ARG 50.A NE GLN 22.A OE1 no hydrogen 2.830 N/A ARG 50.A NH1 GLY 109.A O no hydrogen 3.005 N/A ARG 50.A NH2 GLN 22.A OE1 no hydrogen 2.801 N/A ARG 50.A NH2 THR 99.A OG1 no hydrogen 2.847 N/A ALA 51.A N PHE 208.A O no hydrogen 2.944 N/A LEU 52.A N ILE 20.A O no hydrogen 2.931 N/A TYR 53.A N VAL 206.A O no hydrogen 2.942 N/A ALA 54.A N ASP 18.A O no hydrogen 2.763 N/A ILE 57.A N VAL 204.A O no hydrogen 2.725 N/A HIS 58.A ND1 GLU 3.A OE1 no hydrogen 2.694 N/A ILE 59.A N GLU 202.A O no hydrogen 2.861 N/A TRP 60.A N GLU 202.A O no hydrogen 3.368 N/A TRP 60.A NE1 LEU 200.A O no hydrogen 2.915 N/A ASP 61.A N ARG 66.A O no hydrogen 2.945 N/A ASP 62.A N GLU 202.A OE2 no hydrogen 3.494 N/A SER 63.A OG ASP 61.A OD1 no hydrogen 3.110 N/A SER 63.A OG ASP 61.A OD2 no hydrogen 3.551 N/A THR 64.A N ASP 61.A O no hydrogen 3.330 N/A THR 64.A OG1 ASP 61.A OD2 no hydrogen 2.367 N/A ARG 66.A N ASP 61.A O no hydrogen 3.420 N/A ARG 66.A NE THR 64.A OG1 no hydrogen 2.897 N/A ARG 66.A NH1 MET 1.A O no hydrogen 3.081 N/A ARG 66.A NH1 GLU 3.A OE2 no hydrogen 3.227 N/A ARG 66.A NH1 LEU 233.A O no hydrogen 3.292 N/A ARG 66.A NH2 GLU 3.A OE2 no hydrogen 2.885 N/A ARG 66.A NH2 ASP 61.A OD2 no hydrogen 3.129 N/A ALA 68.A N ILE 59.A O no hydrogen 2.724 N/A SER 69.A N THR 232.A O no hydrogen 3.032 N/A PHE 70.A N TYR 168.A O no hydrogen 3.089 N/A ALA 71.A N THR 230.A O no hydrogen 2.878 N/A THR 72.A N ILE 166.A O no hydrogen 2.811 N/A THR 72.A OG1 SER 228.A O.A no hydrogen 2.582 N/A THR 72.A OG1 SER 228.A O.B no hydrogen 2.652 N/A SER 73.A N SER 228.A O.A no hydrogen 2.974 N/A SER 73.A N SER 228.A O.B no hydrogen 2.942 N/A SER 73.A OG SER 228.A OG.B no hydrogen 2.363 N/A PHE 74.A N VAL 164.A O no hydrogen 3.134 N/A SER 75.A N ASP 226.A OD1 no hydrogen 2.618 N/A SER 75.A OG ASN 163.A OD1 no hydrogen 2.996 N/A SER 75.A OG ASP 226.A OD1 no hydrogen 3.494 N/A PHE 76.A N ALA 162.A O no hydrogen 2.864 N/A VAL 77.A N ASP 223.A O no hydrogen 2.925 N/A GLU 79.A N THR 221.A OG1 no hydrogen 2.879 N/A ALA 80.A N ASN 158.A OD1 no hydrogen 2.830 N/A SER 84.A N ASP 82.A OD1 no hydrogen 2.968 N/A SER 84.A OG ASP 82.A OD1 no hydrogen 2.816 N/A LYS 85.A N ASP 82.A O no hydrogen 2.988 N/A THR 86.A OG1 THR 127.A O no hydrogen 2.856 N/A ASP 88.A N THR 211.A O no hydrogen 2.883 N/A GLY 89.A N THR 211.A O no hydrogen 3.267 N/A ILE 90.A N PHE 125.A O no hydrogen 3.132 N/A ALA 91.A N SER 209.A O no hydrogen 2.774 N/A PHE 92.A N VAL 123.A O no hydrogen 2.975 N/A PHE 93.A N GLY 207.A O no hydrogen 2.758 N/A LEU 94.A N VAL 121.A O no hydrogen 2.854 N/A ALA 95.A N ARG 205.A O no hydrogen 3.074 N/A THR 99.A N PRO 96.A O no hydrogen 2.932 N/A GLN 100.A NE2 ASP 98.A O no hydrogen 3.596 N/A GLN 102.A N GLY 109.A O no hydrogen 2.985 N/A GLN 102.A NE2 GLN 100.A O no hydrogen 3.021 N/A PHE 107.A N ASP 104.A O no hydrogen 3.177 N/A LEU 108.A N GLY 105.A O no hydrogen 3.005 N/A GLY 109.A N LYS 103.A O no hydrogen 2.859 N/A LEU 110.A N PHE 107.A O no hydrogen 2.979 N/A PHE 111.A N PHE 107.A O no hydrogen 3.230 N/A ASN 112.A ND2 GLN 102.A OE1 no hydrogen 3.102 N/A SER 114.A N ASN 112.A OD1 no hydrogen 2.957 N/A SER 114.A OG ASN 112.A OD1 no hydrogen 2.769 N/A LYS 116.A N SER 114.A OG no hydrogen 3.149 N/A GLN 119.A NE2 ALA 199.A O no hydrogen 3.464 N/A THR 120.A N ASN 144.A OD1 no hydrogen 2.802 N/A THR 120.A OG1 GLN 119.A O no hydrogen 2.750 N/A VAL 121.A N LEU 94.A O no hydrogen 2.993 N/A ALA 122.A N ASN 142.A O no hydrogen 2.878 N/A VAL 123.A N PHE 92.A O no hydrogen 2.875 N/A GLU 124.A N GLY 140.A O no hydrogen 2.934 N/A PHE 125.A N ILE 90.A O no hydrogen 2.819 N/A ASP 126.A N HIS 138.A O no hydrogen 2.927 N/A THR 127.A N ASP 88.A O no hydrogen 3.146 N/A THR 127.A OG1 GLU 220.A OE1 no hydrogen 3.351 N/A THR 127.A OG1 GLU 220.A OE2 no hydrogen 2.874 N/A PHE 128.A N ASP 126.A OD1 no hydrogen 3.233 N/A SER 129.A OG PRO 134.A O no hydrogen 2.699 N/A ASN 130.A N ASP 133.A OD2 no hydrogen 2.911 N/A ASN 130.A ND2 ASP 133.A OD2 no hydrogen 3.239 N/A ASP 133.A N ASN 130.A O no hydrogen 3.037 N/A ARG 137.A NE THR 86.A OG1 no hydrogen 3.186 N/A ARG 137.A NE THR 127.A O no hydrogen 3.395 N/A ARG 137.A NH2 GLU 83.A O no hydrogen 3.163 N/A ARG 137.A NH2 THR 86.A OG1 no hydrogen 2.925 N/A HIS 138.A N ASP 126.A O no hydrogen 3.170 N/A HIS 138.A ND1 ALA 136.A O no hydrogen 2.788 N/A ILE 139.A N VAL 152.A O no hydrogen 2.877 N/A GLY 140.A N GLU 124.A O no hydrogen 2.916 N/A ILE 141.A N LYS 150.A O no hydrogen 2.917 N/A ASN 142.A N ALA 122.A O no hydrogen 2.895 N/A ASN 142.A ND2 SER 148.A OG no hydrogen 2.632 N/A ASN 144.A N THR 120.A O no hydrogen 2.889 N/A ASN 144.A ND2 ALA 199.A O no hydrogen 3.085 N/A GLU 147.A N.A SER 145.A OG no hydrogen 3.009 N/A GLU 147.A N.B SER 145.A OG no hydrogen 3.012 N/A MET 149.A N ILE 141.A O no hydrogen 2.742 N/A LYS 150.A NZ SER 191.A O no hydrogen 2.853 N/A VAL 152.A N ILE 139.A O no hydrogen 2.948 N/A TRP 154.A N ARG 137.A O no hydrogen 2.861 N/A TRP 154.A NE1 TYR 181.A OH no hydrogen 3.102 N/A TRP 156.A N TRP 154.A O no hydrogen 3.119 N/A TRP 156.A NE1 VAL 78.A O no hydrogen 3.009 N/A GLU 157.A N TYR 181.A OH no hydrogen 3.102 N/A ASN 158.A ND2 ALA 80.A O no hydrogen 2.998 N/A GLY 159.A N VAL 78.A O no hydrogen 3.004 N/A LYS 160.A N GLU 157.A O no hydrogen 3.204 N/A ALA 162.A N PHE 76.A O no hydrogen 2.870 N/A ASN 163.A N THR 180.A O no hydrogen 2.763 N/A VAL 164.A N PHE 74.A O no hydrogen 2.764 N/A TYR 165.A N SER 178.A O no hydrogen 3.085 N/A ILE 166.A N THR 72.A O no hydrogen 2.870 N/A SER 167.A N THR 176.A O no hydrogen 2.861 N/A TYR 168.A N PHE 70.A O no hydrogen 2.820 N/A TYR 168.A OH VAL 194.A O no hydrogen 2.712 N/A GLU 169.A N THR 174.A O no hydrogen 3.029 N/A ALA 170.A N SER 69.A OG no hydrogen 3.006 N/A THR 172.A N GLU 169.A O no hydrogen 3.297 N/A THR 172.A OG1 GLU 169.A OE1 no hydrogen 2.638 N/A THR 172.A OG1 THR 174.A OG1 no hydrogen 2.681 N/A LYS 173.A N ALA 170.A O no hydrogen 3.207 N/A THR 174.A N GLU 169.A O no hydrogen 3.274 N/A THR 174.A OG1 THR 172.A O no hydrogen 3.342 N/A THR 174.A OG1 THR 172.A OG1 no hydrogen 2.681 N/A LEU 175.A N ALA 192.A O no hydrogen 2.861 N/A THR 176.A N SER 167.A O no hydrogen 2.910 N/A THR 176.A OG1 SER 191.A OG no hydrogen 2.701 N/A ALA 177.A N VAL 190.A O no hydrogen 2.919 N/A SER 178.A N TYR 165.A O no hydrogen 2.870 N/A SER 178.A OG TYR 165.A O no hydrogen 3.494 N/A LEU 179.A N TYR 188.A O no hydrogen 2.907 N/A THR 180.A N ASN 163.A O no hydrogen 2.867 N/A THR 180.A OG1 SER 187.A OG no hydrogen 2.716 N/A TYR 181.A N THR 186.A O.A no hydrogen 2.902 N/A TYR 181.A N THR 186.A O.B no hydrogen 2.841 N/A ALA 185.A N PRO 182.A O no hydrogen 3.386 N/A THR 186.A N.A ASN 184.A OD1 no hydrogen 3.222 N/A THR 186.A N.B ASN 184.A OD1 no hydrogen 3.183 N/A THR 186.A OG1.A ASN 184.A O no hydrogen 3.196 N/A THR 186.A OG1.B ASN 184.A OD1 no hydrogen 2.495 N/A SER 187.A OG THR 180.A OG1 no hydrogen 2.716 N/A TYR 188.A N LEU 179.A O no hydrogen 2.830 N/A VAL 190.A N ALA 177.A O no hydrogen 2.967 N/A SER 191.A OG THR 176.A OG1 no hydrogen 2.701 N/A ALA 192.A N LEU 175.A O no hydrogen 2.862 N/A VAL 194.A N LYS 173.A O no hydrogen 2.795 N/A LYS 197.A NZ ASP 62.A OD1 no hydrogen 3.257 N/A SER 198.A N.A ASP 195.A O no hydrogen 3.270 N/A SER 198.A N.B ASP 195.A O no hydrogen 3.227 N/A SER 198.A OG.A ASP 195.A O no hydrogen 3.080 N/A SER 198.A OG.B ASP 195.A OD2 no hydrogen 2.988 N/A ALA 199.A N ASP 195.A O no hydrogen 3.205 N/A ALA 199.A N LEU 196.A O no hydrogen 3.240 N/A LEU 200.A N LEU 196.A O no hydrogen 2.948 N/A VAL 204.A N ILE 57.A O no hydrogen 2.901 N/A ARG 205.A N ALA 95.A O no hydrogen 2.829 N/A ARG 205.A NE ALA 54.A O no hydrogen 3.009 N/A ARG 205.A NH1 PRO 97.A O no hydrogen 2.800 N/A ARG 205.A NH2 ALA 54.A O no hydrogen 2.929 N/A GLY 207.A N PHE 93.A O no hydrogen 3.047 N/A PHE 208.A N ALA 51.A O no hydrogen 2.872 N/A SER 209.A N ALA 91.A O no hydrogen 2.969 N/A SER 209.A OG LEU 108.A O no hydrogen 2.615 N/A ALA 210.A N GLY 49.A O no hydrogen 2.905 N/A THR 211.A N GLY 89.A O no hydrogen 3.086 N/A THR 211.A OG1 GLY 105.A O no hydrogen 2.661 N/A SER 212.A N SER 47.A O no hydrogen 2.973 N/A SER 212.A OG VAL 44.A O no hydrogen 2.661 N/A SER 215.A OG ASP 217.A OD1 no hydrogen 2.625 N/A SER 215.A OG HIS 218.A ND1 no hydrogen 3.081 N/A HIS 218.A N SER 215.A O no hydrogen 3.172 N/A HIS 218.A ND1 ASP 217.A OD1 no hydrogen 2.774 N/A THR 221.A N GLU 79.A O no hydrogen 2.857 N/A THR 221.A OG1 GLU 79.A O no hydrogen 3.535 N/A HIS 222.A ND1 THR 36.A OG1 no hydrogen 2.822 N/A HIS 222.A NE2 GLU 220.A OE2 no hydrogen 2.545 N/A ASP 223.A N VAL 77.A O no hydrogen 3.043 N/A VAL 224.A N LEU 33.A O no hydrogen 2.792 N/A LEU 225.A N SER 75.A O no hydrogen 2.935 N/A TRP 227.A N PHE 9.A O no hydrogen 3.158 N/A TRP 227.A NE1 THR 72.A OG1 no hydrogen 2.887 N/A SER 228.A N.A SER 73.A O no hydrogen 2.851 N/A SER 228.A N.B SER 73.A O no hydrogen 2.860 N/A SER 228.A OG.A SER 8.A OG.A no hydrogen 2.965 N/A SER 228.A OG.B SER 73.A OG no hydrogen 2.363 N/A PHE 229.A N PHE 7.A O no hydrogen 2.889 N/A THR 230.A N ALA 71.A O no hydrogen 2.939 N/A THR 230.A OG1 VAL 5.A O.A no hydrogen 3.531 N/A THR 230.A OG1 VAL 5.A O.B no hydrogen 3.335 N/A THR 230.A OG1 SER 6.A OG.A no hydrogen 2.699 N/A SER 231.A N VAL 5.A O.A no hydrogen 2.900 N/A SER 231.A N VAL 5.A O.B no hydrogen 2.905 N/A SER 231.A OG SER 69.A O no hydrogen 3.537 N/A THR 232.A N SER 69.A O no hydrogen 2.933 N/A LEU 233.A N GLU 3.A O no hydrogen 2.961 N/A