Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4zk5_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ALA 6.A N ASP 4.A OD1 no hydrogen 3.235 N/A ILE 8.A N PRO 5.A O no hydrogen 2.997 N/A PHE 9.A N PRO 5.A O no hydrogen 2.861 N/A GLU 10.A N ARG 27.A O no hydrogen 3.094 N/A VAL 12.A N LYS 25.A O no hydrogen 2.807 N/A GLU 13.A N LYS 25.A O no hydrogen 3.442 N/A VAL 15.A N VAL 23.A O no hydrogen 3.147 N/A ASN 17.A N VAL 15.A O no hydrogen 2.856 N/A THR 19.A N GLY 16.A O no hydrogen 3.011 N/A THR 19.A OG1 GLY 16.A O no hydrogen 3.065 N/A TYR 20.A OH GLN 141.A O no hydrogen 2.714 N/A GLY 21.A N GLY 18.A O no hydrogen 2.872 N/A TYR 24.A N ILE 37.A O no hydrogen 2.746 N/A LYS 25.A N GLU 13.A O no hydrogen 2.763 N/A GLY 26.A N ALA 35.A O no hydrogen 2.704 N/A ARG 27.A N GLU 10.A O no hydrogen 2.913 N/A ARG 27.A NH2 GLU 10.A OE2 no hydrogen 3.048 N/A HIS 28.A N GLN 33.A O no hydrogen 2.839 N/A HIS 28.A ND1 THR 31.A OG1 no hydrogen 2.802 N/A VAL 29.A N ILE 8.A O no hydrogen 3.086 N/A THR 31.A N HIS 28.A ND1 no hydrogen 3.292 N/A THR 31.A OG1 HIS 28.A ND1 no hydrogen 2.802 N/A GLY 32.A N HIS 28.A O no hydrogen 2.724 N/A GLN 33.A N THR 31.A OG1 no hydrogen 3.206 N/A ALA 35.A N GLY 26.A O no hydrogen 3.337 N/A ALA 36.A N MET 89.A O no hydrogen 2.842 N/A ILE 37.A N TYR 24.A O no hydrogen 2.831 N/A LYS 38.A N LEU 87.A O no hydrogen 2.861 N/A LYS 38.A NZ GLU 53.A OE1 no hydrogen 2.906 N/A LYS 38.A NZ ASP 155.A OD1 no hydrogen 3.006 N/A VAL 39.A N GLN 22.A O no hydrogen 2.909 N/A MET 40.A N LEU 85.A O no hydrogen 3.050 N/A VAL 42.A N ASP 83.A O no hydrogen 2.886 N/A GLU 46.A N THR 43.A O no hydrogen 3.279 N/A GLU 53.A N ILE 50.A O no hydrogen 3.291 N/A MET 56.A N LEU 52.A O no hydrogen 3.162 N/A LEU 57.A N GLU 53.A O no hydrogen 3.406 N/A LYS 58.A N ILE 54.A O no hydrogen 3.081 N/A LYS 59.A N ASN 55.A O no hydrogen 3.445 N/A TYR 60.A N MET 56.A O no hydrogen 3.183 N/A SER 61.A N LEU 57.A O no hydrogen 3.227 N/A SER 61.A OG LEU 57.A O no hydrogen 2.740 N/A HIS 63.A N SER 61.A O no hydrogen 2.863 N/A ASN 65.A N HIS 63.A ND1 no hydrogen 3.064 N/A ASN 65.A ND2 GLU 120.A OE2 no hydrogen 3.045 N/A ASN 65.A ND2 VAL 151.A O no hydrogen 3.142 N/A ILE 66.A N HIS 63.A O no hydrogen 3.023 N/A ALA 67.A N LEU 153.A O no hydrogen 3.119 N/A THR 68.A N GLU 90.A OE1 no hydrogen 2.904 N/A THR 68.A OG1 GLU 90.A OE1 no hydrogen 2.906 N/A TYR 69.A N SER 61.A OG no hydrogen 2.911 N/A TYR 70.A N VAL 88.A O no hydrogen 2.777 N/A GLY 71.A N VAL 88.A O no hydrogen 3.409 N/A PHE 73.A N TRP 86.A O no hydrogen 2.826 N/A ILE 74.A N ARG 3.A O no hydrogen 3.087 N/A LYS 75.A N GLN 84.A O no hydrogen 2.949 N/A LYS 76.A N ASP 4.A OD2 no hydrogen 3.428 N/A SER 77.A N ASP 83.A OD1 no hydrogen 3.095 N/A SER 77.A OG ASP 82.A O no hydrogen 2.791 N/A GLN 84.A N LYS 75.A O no hydrogen 3.285 N/A LEU 85.A N MET 40.A O no hydrogen 3.013 N/A TRP 86.A N PHE 73.A O no hydrogen 2.769 N/A LEU 87.A N LYS 38.A O no hydrogen 2.927 N/A VAL 88.A N GLY 71.A O no hydrogen 2.904 N/A MET 89.A N ALA 36.A O no hydrogen 2.959 N/A GLU 90.A N THR 68.A O no hydrogen 2.753 N/A ALA 94.A N LEU 145.A O no hydrogen 3.175 N/A ILE 97.A N GLY 140.A O no hydrogen 3.205 N/A ILE 97.A N VAL 143.A O no hydrogen 3.093 N/A THR 98.A OG1 GLU 200.A OE2 no hydrogen 2.706 N/A LEU 100.A N SER 96.A O no hydrogen 3.108 N/A VAL 101.A N ILE 97.A O no hydrogen 3.232 N/A LYS 102.A N THR 98.A O no hydrogen 3.184 N/A ASN 103.A N ASP 99.A O no hydrogen 3.021 N/A ASN 103.A N LEU 100.A O no hydrogen 3.180 N/A THR 104.A OG1 LEU 100.A O no hydrogen 2.651 N/A THR 104.A OG1 HIS 280.A NE2 no hydrogen 3.372 N/A ASN 107.A N THR 104.A O no hydrogen 3.062 N/A THR 108.A OG1 LEU 109.A O no hydrogen 3.532 N/A THR 108.A OG1 ALA 202.A O no hydrogen 2.826 N/A LEU 109.A N MET 201.A O no hydrogen 2.977 N/A LYS 110.A NZ ASP 112.A OD1 no hydrogen 2.909 N/A LYS 110.A NZ GLN 276.A OE1 no hydrogen 3.094 N/A TRP 113.A N LYS 110.A O no hydrogen 2.903 N/A ILE 114.A N LYS 110.A O no hydrogen 3.106 N/A ALA 115.A N GLU 111.A O no hydrogen 3.078 N/A TYR 116.A N ASP 112.A O no hydrogen 3.021 N/A TYR 116.A OH ALA 149.A O no hydrogen 3.286 N/A ILE 117.A N TRP 113.A O no hydrogen 2.990 N/A SER 118.A N ILE 114.A O no hydrogen 2.911 N/A SER 118.A OG ILE 114.A O no hydrogen 2.722 N/A ARG 119.A N ALA 115.A O no hydrogen 3.235 N/A GLU 120.A N TYR 116.A O no hydrogen 3.143 N/A ILE 121.A N ILE 117.A O no hydrogen 2.930 N/A LEU 122.A N SER 118.A O no hydrogen 2.898 N/A ARG 123.A N ARG 119.A O no hydrogen 2.827 N/A ARG 123.A NH1 GLU 120.A OE1 no hydrogen 3.169 N/A GLY 124.A N GLU 120.A O no hydrogen 3.019 N/A LEU 125.A N ILE 121.A O no hydrogen 2.811 N/A ALA 126.A N LEU 122.A O no hydrogen 2.781 N/A HIS 127.A N ARG 123.A O no hydrogen 3.358 N/A LEU 128.A N GLY 124.A O no hydrogen 3.381 N/A HIS 129.A N LEU 125.A O no hydrogen 2.872 N/A HIS 129.A ND1 THR 255.A OG1 no hydrogen 2.764 N/A HIS 129.A NE2 ASP 190.A OD2 no hydrogen 2.814 N/A ILE 130.A N ALA 126.A O no hydrogen 3.025 N/A HIS 131.A N LEU 128.A O no hydrogen 3.154 N/A HIS 132.A N HIS 129.A O no hydrogen 2.969 N/A VAL 133.A N LEU 128.A O no hydrogen 2.814 N/A HIS 135.A N ASP 190.A OD2 no hydrogen 2.923 N/A HIS 135.A NE2 VAL 154.A O no hydrogen 2.761 N/A ARG 136.A N ASP 190.A OD1 no hydrogen 2.948 N/A ARG 136.A NE VAL 158.A O no hydrogen 2.717 N/A ASP 137.A N HIS 135.A ND1 no hydrogen 3.020 N/A GLY 140.A N GLU 200.A OE1 no hydrogen 3.059 N/A ASN 142.A N LYS 139.A O no hydrogen 2.791 N/A ASN 142.A ND2 ASP 137.A O no hydrogen 2.790 N/A ASN 142.A ND2 ASP 137.A OD2 no hydrogen 2.936 N/A VAL 143.A N GLY 140.A O no hydrogen 3.431 N/A LEU 144.A N LYS 152.A O no hydrogen 2.898 N/A LEU 145.A N GLY 95.A O no hydrogen 2.787 N/A THR 146.A N GLU 150.A O no hydrogen 3.000 N/A GLU 147.A N GLU 147.A OE1 no hydrogen 2.990 N/A ALA 149.A N THR 146.A O no hydrogen 3.099 N/A GLU 150.A N THR 146.A OG1 no hydrogen 3.180 N/A LYS 152.A N LEU 144.A O no hydrogen 2.803 N/A LYS 152.A NZ ARG 64.A O no hydrogen 3.141 N/A LYS 152.A NZ GLU 90.A OE1 no hydrogen 2.819 N/A LEU 153.A N ASN 65.A O no hydrogen 2.771 N/A VAL 154.A N ASN 142.A O no hydrogen 2.969 N/A GLY 157.A N ASP 155.A OD1 no hydrogen 2.924 N/A SER 159.A OG PHE 156.A O no hydrogen 3.109 N/A ALA 160.A N ILE 134.A O no hydrogen 2.922 N/A TYR 168.A OH MET 211.A O no hydrogen 2.742 N/A TRP 169.A NE1 GLU 200.A OE1 no hydrogen 3.148 N/A MET 170.A N PRO 167.A O no hydrogen 2.989 N/A GLU 173.A N GLU 173.A OE1 no hydrogen 2.815 N/A VAL 174.A N ALA 171.A O no hydrogen 3.182 N/A ILE 175.A N PRO 172.A O no hydrogen 3.252 N/A CYS 177.A N ASN 180.A O no hydrogen 2.856 N/A CYS 177.A SG GLU 179.A OE1 no hydrogen 3.342 N/A GLU 179.A N GLU 179.A OE1 no hydrogen 2.801 N/A ASN 180.A ND2 GLU 173.A O no hydrogen 2.866 N/A ASN 180.A ND2 ILE 175.A O no hydrogen 3.427 N/A THR 184.A N ASN 180.A OD1 no hydrogen 3.364 N/A ARG 188.A N ASP 186.A OD1 no hydrogen 3.039 N/A ARG 188.A NE ASP 186.A OD1 no hydrogen 2.994 N/A ARG 188.A NH1 ASP 186.A OD2 no hydrogen 3.432 N/A ARG 188.A NH2 MET 250.A O no hydrogen 3.254 N/A ARG 188.A NH2 ARG 252.A O no hydrogen 3.536 N/A SER 189.A N ASP 186.A O no hydrogen 3.204 N/A SER 189.A OG GLU 173.A OE2 no hydrogen 2.912 N/A SER 189.A OG ASP 186.A O no hydrogen 2.963 N/A ASP 190.A N TYR 187.A O no hydrogen 3.318 N/A LEU 191.A N ARG 188.A O no hydrogen 3.061 N/A TRP 192.A N ARG 188.A O no hydrogen 3.407 N/A SER 193.A N SER 189.A O no hydrogen 3.261 N/A SER 193.A OG TRP 169.A O no hydrogen 2.930 N/A SER 193.A OG SER 189.A O no hydrogen 3.033 N/A CYS 194.A N ASP 190.A O no hydrogen 2.808 N/A GLY 195.A N LEU 191.A O no hydrogen 3.023 N/A ILE 196.A N TRP 192.A O no hydrogen 2.991 N/A THR 197.A N SER 193.A O no hydrogen 2.982 N/A THR 197.A OG1 SER 193.A O no hydrogen 2.718 N/A ALA 198.A N CYS 194.A O no hydrogen 3.086 N/A ILE 199.A N GLY 195.A O no hydrogen 3.185 N/A GLU 200.A N ILE 196.A O no hydrogen 2.846 N/A MET 201.A N THR 197.A O no hydrogen 2.887 N/A ALA 202.A N ALA 198.A O no hydrogen 3.033 N/A GLU 203.A N ILE 199.A O no hydrogen 2.787 N/A GLY 204.A N GLU 200.A O no hydrogen 2.800 N/A CYS 209.A N PRO 206.A O no hydrogen 3.354 N/A MET 211.A N LEU 208.A O no hydrogen 3.105 N/A MET 214.A N HIS 212.A ND1 no hydrogen 3.090 N/A ARG 215.A N HIS 212.A O no hydrogen 2.933 N/A ALA 216.A N HIS 212.A O no hydrogen 2.984 N/A LEU 217.A N PRO 213.A O no hydrogen 3.002 N/A PHE 218.A N MET 214.A O no hydrogen 3.233 N/A LEU 219.A N ARG 215.A O no hydrogen 2.862 N/A ILE 220.A N ALA 216.A O no hydrogen 2.891 N/A ARG 222.A N LEU 219.A O no hydrogen 2.864 N/A ARG 222.A NH2 PHE 218.A O no hydrogen 2.780 N/A ASN 223.A N LEU 219.A O no hydrogen 2.717 N/A LYS 229.A N GLU 203.A OE2 no hydrogen 2.815 N/A SER 234.A N GLU 111.A OE1 no hydrogen 2.747 N/A SER 234.A OG GLU 111.A OE1 no hydrogen 3.328 N/A SER 234.A OG GLU 111.A OE2 no hydrogen 2.688 N/A LYS 236.A NZ ASP 266.A OD2 no hydrogen 3.398 N/A PHE 237.A N SER 234.A OG no hydrogen 3.174 N/A PHE 238.A N SER 234.A O no hydrogen 3.162 N/A SER 239.A N LYS 235.A O no hydrogen 3.146 N/A SER 239.A OG HIS 261.A NE2 no hydrogen 2.967 N/A PHE 240.A N LYS 236.A O no hydrogen 3.081 N/A ILE 241.A N PHE 237.A O no hydrogen 3.041 N/A GLU 242.A N PHE 238.A O no hydrogen 2.932 N/A GLY 243.A N SER 239.A O no hydrogen 2.791 N/A CYS 244.A N PHE 240.A O no hydrogen 2.846 N/A CYS 244.A SG PHE 240.A O no hydrogen 3.328 N/A LEU 245.A N ILE 241.A O no hydrogen 2.798 N/A LYS 247.A NZ PRO 221.A O no hydrogen 3.030 N/A LYS 247.A NZ ASN 223.A O no hydrogen 2.810 N/A MET 250.A N ASN 248.A OD1 no hydrogen 3.063 N/A GLN 251.A N ASN 248.A O no hydrogen 3.240 N/A ARG 252.A N TYR 249.A O no hydrogen 3.171 N/A ARG 252.A NE VAL 246.A O no hydrogen 2.903 N/A ARG 252.A NH1 GLU 173.A OE2 no hydrogen 2.783 N/A ARG 252.A NH1 ARG 188.A O no hydrogen 3.031 N/A ARG 252.A NH2 GLU 173.A OE1 no hydrogen 3.091 N/A ARG 252.A NH2 VAL 246.A O no hydrogen 2.799 N/A ARG 252.A NH2 LYS 247.A O no hydrogen 3.286 N/A SER 254.A N GLN 257.A OE1 no hydrogen 2.938 N/A SER 254.A OG GLN 257.A OE1 no hydrogen 3.119 N/A THR 255.A OG1 HIS 129.A ND1 no hydrogen 2.764 N/A GLN 257.A N SER 254.A OG no hydrogen 3.172 N/A LEU 258.A N SER 254.A O no hydrogen 2.951 N/A LEU 259.A N THR 255.A O no hydrogen 2.940 N/A LEU 259.A N GLU 256.A O no hydrogen 3.257 N/A LYS 260.A N GLU 256.A O no hydrogen 3.290 N/A HIS 261.A N LEU 258.A O no hydrogen 3.302 N/A HIS 261.A NE2 SER 239.A OG no hydrogen 2.967 N/A PHE 263.A N HIS 261.A ND1 no hydrogen 3.148 N/A ILE 264.A N HIS 261.A O no hydrogen 2.817 N/A ARG 265.A N HIS 261.A O no hydrogen 2.783 N/A ARG 265.A NH2 ASP 266.A OD1 no hydrogen 3.443 N/A ARG 265.A NH2 ASP 266.A OD2 no hydrogen 3.167 N/A ASP 266.A N PRO 262.A O no hydrogen 2.920 N/A GLN 272.A N GLN 272.A OE1 no hydrogen 2.782 N/A VAL 273.A N ASN 269.A O no hydrogen 2.792 N/A ARG 274.A N GLU 270.A O no hydrogen 3.252 N/A ILE 275.A N ARG 271.A O no hydrogen 3.227 N/A GLN 276.A N GLN 272.A O no hydrogen 2.947 N/A LEU 277.A N VAL 273.A O no hydrogen 2.862 N/A LYS 278.A N ARG 274.A O no hydrogen 3.184 N/A LYS 278.A NZ ASP 282.A OD1 no hydrogen 3.412 N/A LYS 278.A NZ ASP 282.A OD2 no hydrogen 3.448 N/A ASP 279.A N ILE 275.A O no hydrogen 2.880 N/A HIS 280.A N GLN 276.A O no hydrogen 3.148 N/A ILE 281.A N LEU 277.A O no hydrogen 3.192 N/A ASP 282.A N LYS 278.A O no hydrogen 3.415 N/A ARG 283.A N ASP 279.A O no hydrogen 3.151 N/A THR 284.A N HIS 280.A O no hydrogen 3.349 N/A THR 284.A OG1 HIS 280.A O no hydrogen 2.733 N/A ARG 285.A N ILE 281.A O no hydrogen 3.152 N/A LYS 286.A N ASP 282.A O no hydrogen 3.284 N/A