Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 5ei8_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): MET 3.A N TYR 10.A O no hydrogen 2.974 N/A SER 4.A OG ARG 8.A O no hydrogen 3.483 N/A VAL 5.A N ARG 8.A O no hydrogen 2.834 N/A LYS 6.A N GLU 77.A OE1 no hydrogen 2.748 N/A LYS 6.A NZ TYR 76.A O no hydrogen 2.807 N/A ARG 8.A N VAL 5.A O no hydrogen 2.903 N/A TYR 10.A N MET 3.A O no hydrogen 2.860 N/A SER 11.A N LEU 28.A O no hydrogen 2.826 N/A ILE 12.A N GLN 1.A O no hydrogen 3.094 N/A LEU 13.A N GLN 26.A O no hydrogen 2.787 N/A LYS 14.A N GLN 26.A O no hydrogen 3.451 N/A GLN 15.A NE2 GLY 17.A O no hydrogen 3.547 N/A GLY 17.A N VAL 24.A O no hydrogen 3.227 N/A SER 18.A N GLN 157.A O no hydrogen 3.088 N/A SER 18.A OG ASP 159.A OD1 no hydrogen 2.884 N/A GLY 19.A N SER 22.A O no hydrogen 2.929 N/A SER 22.A N GLY 19.A O no hydrogen 2.911 N/A SER 22.A OG TYR 53.A OH no hydrogen 2.786 N/A LYS 23.A N TYR 39.A O no hydrogen 2.995 N/A VAL 24.A N GLY 17.A O no hydrogen 2.869 N/A PHE 25.A N ILE 37.A O no hydrogen 2.904 N/A GLN 26.A N LYS 14.A O no hydrogen 2.703 N/A VAL 27.A N TYR 35.A O no hydrogen 2.791 N/A LEU 28.A N SER 11.A O no hydrogen 2.890 N/A ASN 29.A N GLN 33.A O no hydrogen 3.016 N/A ASN 29.A ND2 GLN 33.A OE1 no hydrogen 2.787 N/A LYS 32.A N ASN 29.A O no hydrogen 2.848 N/A GLN 33.A N ASN 29.A OD1 no hydrogen 2.622 N/A TYR 35.A N VAL 27.A O no hydrogen 2.871 N/A ALA 36.A N MET 87.A O no hydrogen 2.764 N/A ILE 37.A N PHE 25.A O no hydrogen 2.838 N/A LYS 38.A N MET 85.A O no hydrogen 2.848 N/A LYS 38.A NZ ASN 154.A OD1 no hydrogen 2.811 N/A TYR 39.A N LYS 23.A O no hydrogen 2.779 N/A VAL 40.A N ILE 83.A O no hydrogen 3.007 N/A ASN 41.A N SER 21.A O no hydrogen 2.960 N/A LEU 42.A N GLN 81.A O no hydrogen 2.806 N/A GLU 43.A N ASN 41.A OD1 no hydrogen 3.181 N/A ALA 45.A N LEU 42.A O no hydrogen 3.138 N/A THR 49.A OG1 ASP 46.A OD1 no hydrogen 2.661 N/A LEU 50.A N ASP 46.A O no hydrogen 3.005 N/A ASP 51.A N ASN 47.A O no hydrogen 3.301 N/A SER 52.A N GLN 48.A O no hydrogen 3.354 N/A SER 52.A OG GLN 48.A O no hydrogen 3.301 N/A TYR 53.A N THR 49.A O no hydrogen 3.299 N/A TYR 53.A OH SER 22.A OG no hydrogen 2.786 N/A ARG 54.A N LEU 50.A O no hydrogen 3.050 N/A ARG 54.A NH1 ASP 51.A OD1 no hydrogen 3.052 N/A ASN 55.A N ASP 51.A O no hydrogen 3.094 N/A GLU 56.A N SER 52.A O no hydrogen 3.075 N/A ILE 57.A N TYR 53.A O no hydrogen 3.027 N/A ALA 58.A N ARG 54.A O no hydrogen 3.227 N/A TYR 59.A N ASN 55.A O no hydrogen 3.141 N/A LEU 60.A N GLU 56.A O no hydrogen 3.032 N/A ASN 61.A N ILE 57.A O no hydrogen 2.872 N/A LYS 62.A N ALA 58.A O no hydrogen 2.880 N/A LEU 63.A N TYR 59.A O no hydrogen 2.968 N/A GLN 64.A NE2 LEU 60.A O no hydrogen 2.974 N/A GLN 64.A NE2 ILE 71.A O no hydrogen 3.043 N/A SER 67.A N LEU 63.A O no hydrogen 3.288 N/A LYS 69.A N SER 67.A OG no hydrogen 2.859 N/A LYS 69.A NZ ASP 68.A OD1 no hydrogen 2.718 N/A LYS 69.A NZ ASP 68.A OD2 no hydrogen 3.466 N/A LYS 69.A NZ GLU 118.A OE1 no hydrogen 3.242 N/A ILE 71.A N LEU 147.A O no hydrogen 3.103 N/A ARG 72.A N GLU 88.A OE1 no hydrogen 2.741 N/A ARG 72.A NE ILE 70.A O no hydrogen 3.160 N/A ARG 72.A NH1 GLN 64.A O no hydrogen 2.845 N/A ARG 72.A NH2 GLN 64.A O no hydrogen 2.945 N/A ARG 72.A NH2 ILE 70.A O no hydrogen 2.997 N/A LEU 73.A N GLN 64.A OE1 no hydrogen 3.055 N/A TYR 74.A N VAL 86.A O no hydrogen 2.803 N/A ASP 75.A N VAL 86.A O no hydrogen 3.295 N/A TYR 76.A N ASP 75.A OD1 no hydrogen 3.138 N/A GLU 77.A N TYR 84.A O no hydrogen 2.790 N/A THR 79.A N TYR 82.A O no hydrogen 2.910 N/A GLN 81.A N THR 79.A OG1 no hydrogen 3.361 N/A TYR 82.A N THR 79.A OG1 no hydrogen 3.357 N/A TYR 82.A OH GLU 77.A OE2 no hydrogen 2.976 N/A ILE 83.A N VAL 40.A O no hydrogen 2.913 N/A TYR 84.A N GLU 77.A O no hydrogen 2.686 N/A MET 85.A N LYS 38.A O no hydrogen 3.042 N/A VAL 86.A N ASP 75.A O no hydrogen 2.698 N/A MET 87.A N ALA 36.A O no hydrogen 2.806 N/A GLU 88.A N ARG 72.A O no hydrogen 3.225 N/A CYS 89.A SG GLY 90.A O no hydrogen 3.661 N/A ASN 91.A N ILE 140.A O no hydrogen 2.874 N/A LEU 94.A N PHE 138.A O no hydrogen 2.869 N/A SER 96.A N ASP 93.A OD2 no hydrogen 3.168 N/A SER 96.A OG ASP 93.A OD1 no hydrogen 2.664 N/A SER 96.A OG ASP 93.A OD2 no hydrogen 3.315 N/A TRP 97.A N ASP 93.A O no hydrogen 3.084 N/A LEU 98.A N LEU 94.A O no hydrogen 2.762 N/A LYS 99.A N ASN 95.A O no hydrogen 3.131 N/A LYS 100.A N SER 96.A O no hydrogen 3.285 N/A LYS 100.A N TRP 97.A O no hydrogen 3.189 N/A LYS 101.A N TRP 97.A O no hydrogen 3.164 N/A TRP 107.A N ASP 105.A OD1 no hydrogen 3.220 N/A ARG 109.A N ASP 105.A O no hydrogen 2.999 N/A ARG 109.A NH1 MET 193.A O no hydrogen 2.807 N/A ARG 109.A NH2 GLU 227.A OE1 no hydrogen 2.909 N/A LYS 110.A N PRO 106.A O no hydrogen 3.199 N/A LYS 110.A NZ TYR 256.A O no hydrogen 3.230 N/A LYS 110.A NZ ILE 259.A O no hydrogen 2.855 N/A SER 111.A N TRP 107.A O no hydrogen 3.113 N/A TYR 112.A N GLU 108.A O no hydrogen 2.994 N/A TRP 113.A N ARG 109.A O no hydrogen 3.061 N/A LYS 114.A N LYS 110.A O no hydrogen 3.027 N/A ASN 115.A N SER 111.A O no hydrogen 3.104 N/A MET 116.A N TYR 112.A O no hydrogen 2.851 N/A LEU 117.A N TRP 113.A O no hydrogen 2.905 N/A GLU 118.A N LYS 114.A O no hydrogen 2.950 N/A ALA 119.A N ASN 115.A O no hydrogen 2.921 N/A VAL 120.A N MET 116.A O no hydrogen 2.945 N/A HIS 121.A N LEU 117.A O no hydrogen 2.851 N/A THR 122.A N GLU 118.A O no hydrogen 3.151 N/A THR 122.A OG1 GLU 118.A O no hydrogen 2.779 N/A ILE 123.A N ALA 119.A O no hydrogen 3.391 N/A HIS 124.A N VAL 120.A O no hydrogen 3.104 N/A HIS 124.A NE2 ASP 182.A OD2 no hydrogen 2.635 N/A GLN 125.A N HIS 121.A O no hydrogen 3.079 N/A HIS 126.A N ILE 123.A O no hydrogen 3.205 N/A HIS 126.A ND1 THR 122.A O no hydrogen 3.048 N/A GLY 127.A N HIS 124.A O no hydrogen 2.992 N/A ILE 128.A N ILE 123.A O no hydrogen 3.048 N/A HIS 130.A N ASP 182.A OD2 no hydrogen 3.091 N/A SER 131.A N ASP 182.A OD1 no hydrogen 2.822 N/A SER 131.A OG HIS 130.A O no hydrogen 2.029 N/A ASP 132.A N HIS 130.A ND1 no hydrogen 2.919 N/A LYS 134.A N ASN 137.A OD1 no hydrogen 2.943 N/A LYS 134.A NZ ASP 132.A O no hydrogen 2.877 N/A LYS 134.A NZ ASP 132.A OD2 no hydrogen 2.915 N/A ASN 137.A N LYS 134.A O no hydrogen 3.080 N/A ASN 137.A ND2 ASP 149.A OD1 no hydrogen 2.929 N/A PHE 138.A N PRO 135.A O no hydrogen 3.020 N/A LEU 139.A N LYS 146.A O no hydrogen 2.842 N/A ILE 140.A N ILE 92.A O no hydrogen 2.921 N/A VAL 141.A N MET 144.A O no hydrogen 2.820 N/A ASP 142.A N ASN 91.A OD1 no hydrogen 3.391 N/A MET 144.A N VAL 141.A O no hydrogen 3.266 N/A LEU 145.A N ASN 115.A OD1 no hydrogen 2.908 N/A LYS 146.A N LEU 139.A O no hydrogen 2.822 N/A LYS 146.A NZ ASP 68.A O no hydrogen 2.877 N/A LYS 146.A NZ GLU 88.A OE1 no hydrogen 3.373 N/A LYS 146.A NZ GLU 88.A OE2 no hydrogen 3.437 N/A LEU 147.A N LYS 69.A O no hydrogen 2.783 N/A ILE 148.A N ASN 137.A O no hydrogen 2.763 N/A GLY 151.A N ASP 149.A OD2 no hydrogen 2.939 N/A ILE 152.A N GLU 56.A OE1 no hydrogen 2.966 N/A ALA 153.A N GLU 56.A OE1 no hydrogen 3.081 N/A ASN 154.A ND2 GLN 155.A O no hydrogen 3.569 N/A GLN 155.A NE2 VAL 160.A O no hydrogen 2.814 N/A GLN 157.A N SER 18.A O no hydrogen 2.884 N/A ASP 159.A N ILE 16.A O no hydrogen 3.144 N/A ASN 164.A N THR 162.A OG1 no hydrogen 3.415 N/A MET 166.A N VAL 163.A O no hydrogen 3.238 N/A GLU 169.A N GLU 169.A OE1 no hydrogen 3.007 N/A ALA 170.A N PRO 167.A O no hydrogen 3.100 N/A LYS 172.A N PRO 168.A O no hydrogen 2.949 N/A ASP 173.A N GLU 169.A O no hydrogen 3.472 N/A MET 174.A N LYS 172.A O no hydrogen 2.969 N/A ILE 177.A N SER 175.A OG no hydrogen 3.223 N/A SER 178.A N SER 181.A OG no hydrogen 3.035 N/A LYS 180.A NZ PRO 242.A O no hydrogen 3.143 N/A LYS 180.A NZ ARG 245.A O no hydrogen 2.930 N/A SER 181.A N SER 178.A O no hydrogen 2.810 N/A SER 181.A OG GLU 169.A OE2 no hydrogen 2.806 N/A SER 181.A OG SER 178.A O no hydrogen 3.068 N/A ASP 182.A N PRO 179.A O no hydrogen 3.241 N/A TRP 184.A N LYS 180.A O no hydrogen 3.337 N/A SER 185.A N SER 181.A O no hydrogen 3.398 N/A SER 185.A OG TYR 165.A O no hydrogen 2.895 N/A SER 185.A OG SER 181.A O no hydrogen 3.390 N/A LEU 186.A N ASP 182.A O no hydrogen 2.853 N/A GLY 187.A N VAL 183.A O no hydrogen 2.779 N/A CYS 188.A N TRP 184.A O no hydrogen 2.929 N/A CYS 188.A SG ASN 164.A O no hydrogen 3.877 N/A CYS 188.A SG TRP 184.A O no hydrogen 3.517 N/A ILE 189.A N SER 185.A O no hydrogen 3.148 N/A LEU 190.A N LEU 186.A O no hydrogen 2.942 N/A TYR 191.A N GLY 187.A O no hydrogen 2.854 N/A TYR 191.A OH GLU 221.A O no hydrogen 2.700 N/A TYR 192.A N CYS 188.A O no hydrogen 3.005 N/A MET 193.A N ILE 189.A O no hydrogen 3.016 N/A THR 194.A N TYR 191.A O no hydrogen 3.018 N/A THR 194.A OG1 LEU 190.A O no hydrogen 2.741 N/A TYR 195.A N TYR 191.A O no hydrogen 2.698 N/A TYR 195.A OH PRO 223.A O no hydrogen 2.669 N/A GLY 196.A N TYR 192.A O no hydrogen 2.803 N/A LYS 197.A NZ THR 198.A O no hydrogen 3.317 N/A LYS 197.A NZ GLN 202.A OE1 no hydrogen 2.753 N/A GLN 201.A N THR 198.A O no hydrogen 3.303 N/A GLN 202.A N GLN 202.A OE1 no hydrogen 2.408 N/A GLN 202.A NE2 PRO 199.A O no hydrogen 3.100 N/A ILE 203.A N PHE 200.A O no hydrogen 3.277 N/A GLN 206.A NE2 ILE 204.A O no hydrogen 3.004 N/A ILE 207.A N ASN 205.A OD1 no hydrogen 3.095 N/A SER 208.A N ASN 205.A OD1 no hydrogen 3.279 N/A LYS 209.A N ASN 205.A O no hydrogen 2.787 N/A LYS 209.A NZ ASN 164.A OD1 no hydrogen 2.776 N/A LYS 209.A NZ PHE 200.A O no hydrogen 2.780 N/A LYS 209.A NZ GLN 201.A O no hydrogen 3.491 N/A LYS 209.A NZ ILE 203.A O no hydrogen 3.165 N/A LEU 210.A N GLN 206.A O no hydrogen 2.908 N/A HIS 211.A N ILE 207.A O no hydrogen 3.014 N/A ALA 212.A N SER 208.A O no hydrogen 2.827 N/A ALA 212.A N LYS 209.A O no hydrogen 3.172 N/A ILE 213.A N LYS 209.A O no hydrogen 3.169 N/A ASP 215.A N ALA 212.A O no hydrogen 3.442 N/A ASN 217.A N ASP 215.A OD1 no hydrogen 3.274 N/A HIS 218.A N ASP 215.A O no hydrogen 3.147 N/A GLN 231.A N GLU 227.A O no hydrogen 3.322 N/A GLN 231.A NE2 ASP 224.A OD1 no hydrogen 3.376 N/A ASP 232.A N LYS 228.A O no hydrogen 3.003 N/A VAL 233.A N ASP 229.A O no hydrogen 2.823 N/A LEU 234.A N LEU 230.A O no hydrogen 3.026 N/A LYS 235.A N GLN 231.A O no hydrogen 3.212 N/A CYS 236.A N ASP 232.A O no hydrogen 2.993 N/A CYS 236.A SG ASP 232.A O no hydrogen 3.546 N/A CYS 236.A SG ASP 232.A OD2 no hydrogen 3.783 N/A CYS 237.A N VAL 233.A O no hydrogen 3.008 N/A CYS 237.A N LEU 234.A O no hydrogen 3.114 N/A CYS 237.A SG VAL 233.A O no hydrogen 3.391 N/A LEU 238.A N LEU 234.A O no hydrogen 2.952 N/A ARG 240.A NE ILE 213.A O no hydrogen 2.903 N/A ARG 240.A NH2 ALA 212.A O no hydrogen 2.935 N/A LYS 243.A N ASP 241.A OD1 no hydrogen 3.217 N/A GLN 244.A N ASP 241.A O no hydrogen 3.019 N/A ARG 245.A N ASP 241.A O no hydrogen 2.964 N/A ARG 245.A N PRO 242.A O no hydrogen 3.081 N/A ARG 245.A NE LYS 239.A O no hydrogen 2.792 N/A ARG 245.A NH1 GLU 169.A OE1 no hydrogen 3.098 N/A ARG 245.A NH1 GLU 169.A OE2 no hydrogen 2.930 N/A ARG 245.A NH1 LYS 180.A O no hydrogen 2.846 N/A ARG 245.A NH2 GLU 169.A OE1 no hydrogen 2.808 N/A ARG 245.A NH2 LYS 239.A O no hydrogen 3.218 N/A ARG 245.A NH2 ARG 240.A O no hydrogen 3.263 N/A ILE 246.A N CYS 236.A O no hydrogen 3.249 N/A GLU 250.A N SER 247.A OG no hydrogen 3.383 N/A LEU 251.A N SER 247.A O no hydrogen 2.832 N/A LEU 252.A N ILE 248.A O no hydrogen 2.964 N/A ALA 253.A N GLU 250.A O no hydrogen 3.063 N/A HIS 254.A N LEU 251.A O no hydrogen 3.073 N/A HIS 254.A NE2 ASP 232.A OD2 no hydrogen 3.092 N/A TYR 256.A N HIS 254.A ND1 no hydrogen 2.814 N/A GLN 258.A N HIS 254.A O no hydrogen 3.101 N/A GLN 258.A N PRO 255.A O no hydrogen 3.277 N/A GLN 258.A NE2 LEU 252.A O no hydrogen 2.898 N/A ILE 259.A N PRO 255.A O no hydrogen 2.727 N/A