Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 7n4s_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ILE 4.A N VAL 70.A O no hydrogen 3.085 N/A LYS 7.A N ASP 5.A OD1 no hydrogen 3.051 N/A ASP 8.A N ASP 5.A O no hydrogen 2.941 N/A LEU 9.A N PRO 6.A O no hydrogen 3.148 N/A THR 10.A N LYS 27.A O no hydrogen 2.909 N/A LEU 12.A N TYR 25.A O no hydrogen 2.910 N/A LYS 13.A N TYR 25.A O no hydrogen 3.310 N/A LEU 15.A N VAL 23.A O no hydrogen 2.664 N/A GLY 16.A N VAL 23.A O no hydrogen 3.001 N/A THR 17.A OG1 GLU 14.A OE2 no hydrogen 2.441 N/A GLY 18.A N GLY 21.A O no hydrogen 2.911 N/A GLY 21.A N GLY 18.A O no hydrogen 2.907 N/A VAL 22.A N MET 38.A O no hydrogen 3.007 N/A VAL 23.A N GLY 16.A O no hydrogen 2.860 N/A LYS 24.A N ILE 36.A O no hydrogen 2.943 N/A TYR 25.A N LYS 13.A O no hydrogen 2.605 N/A TYR 25.A OH ASP 33.A OD1 no hydrogen 2.780 N/A GLY 26.A N VAL 34.A O no hydrogen 2.963 N/A LYS 27.A N THR 10.A O no hydrogen 2.903 N/A LYS 27.A NZ GLN 31.A O no hydrogen 2.999 N/A LYS 27.A NZ ASP 33.A OD1 no hydrogen 3.104 N/A TRP 28.A N TYR 32.A O no hydrogen 2.800 N/A ARG 29.A N ASP 8.A O no hydrogen 2.847 N/A ARG 29.A NE ASP 8.A OD2 no hydrogen 2.886 N/A ARG 29.A NH2 ASP 8.A OD2 no hydrogen 3.274 N/A GLN 31.A N TRP 28.A O no hydrogen 3.251 N/A TYR 32.A N TRP 28.A O no hydrogen 3.031 N/A VAL 34.A N GLY 26.A O no hydrogen 2.899 N/A ALA 35.A N THR 81.A O no hydrogen 2.945 N/A ILE 36.A N LYS 24.A O no hydrogen 2.879 N/A LYS 37.A N ILE 79.A O no hydrogen 2.889 N/A LYS 37.A NZ ASP 146.A OD1 no hydrogen 2.752 N/A MET 38.A N VAL 22.A O no hydrogen 2.829 N/A ILE 39.A N ILE 77.A O no hydrogen 3.089 N/A LYS 40.A N PHE 20.A O no hydrogen 3.271 N/A SER 43.A N LYS 40.A O no hydrogen 3.129 N/A SER 43.A OG LYS 40.A O no hydrogen 2.897 N/A SER 45.A N TYR 152.A O no hydrogen 2.762 N/A SER 45.A OG GLU 48.A OE2 no hydrogen 2.694 N/A PHE 49.A N SER 45.A O no hydrogen 3.088 N/A ILE 50.A N GLU 46.A O no hydrogen 2.897 N/A GLU 51.A N ASP 47.A O no hydrogen 2.993 N/A GLU 52.A N GLU 48.A O no hydrogen 2.992 N/A ALA 53.A N PHE 49.A O no hydrogen 2.865 N/A ALA 53.A N ILE 50.A O no hydrogen 3.231 N/A LYS 54.A NZ GLU 51.A OE1 no hydrogen 3.120 N/A LYS 54.A NZ GLU 51.A OE2 no hydrogen 3.464 N/A MET 56.A N GLU 52.A O no hydrogen 2.951 N/A MET 57.A N ALA 53.A O no hydrogen 2.922 N/A MET 57.A N LYS 54.A O no hydrogen 3.234 N/A ASN 58.A N VAL 55.A O no hydrogen 3.131 N/A LEU 59.A N MET 56.A O no hydrogen 3.230 N/A SER 60.A N TYR 118.A OH no hydrogen 2.923 N/A SER 60.A OG GLN 66.A OE1 no hydrogen 3.476 N/A LYS 63.A N HIS 61.A ND1 no hydrogen 3.019 N/A LYS 63.A NZ ASP 111.A OD1 no hydrogen 2.373 N/A LYS 63.A NZ GLU 114.A OE1 no hydrogen 3.019 N/A LEU 64.A N HIS 61.A O no hydrogen 3.123 N/A VAL 65.A N VAL 144.A O no hydrogen 2.902 N/A GLN 66.A N GLU 82.A OE1 no hydrogen 3.123 N/A TYR 68.A N ILE 80.A O no hydrogen 2.747 N/A GLY 69.A N ILE 80.A O no hydrogen 3.052 N/A VAL 70.A N TRP 2.A O no hydrogen 3.051 N/A CYS 71.A N PHE 78.A O no hydrogen 2.870 N/A CYS 71.A SG ILE 4.A O no hydrogen 3.258 N/A THR 72.A OG1 GLU 3.A OE1 no hydrogen 3.232 N/A THR 72.A OG1 GLU 3.A OE2 no hydrogen 2.410 N/A PHE 78.A N CYS 71.A O no hydrogen 2.918 N/A ILE 79.A N LYS 37.A O no hydrogen 2.876 N/A ILE 80.A N GLY 69.A O no hydrogen 2.886 N/A THR 81.A N ALA 35.A O no hydrogen 3.011 N/A THR 81.A OG1 GLU 82.A O no hydrogen 3.231 N/A GLU 82.A N GLN 66.A O no hydrogen 2.847 N/A ASN 86.A N VAL 136.A O no hydrogen 2.870 N/A ASN 86.A ND2 ASN 137.A O no hydrogen 2.811 N/A GLY 87.A N MET 84.A O no hydrogen 2.944 N/A LEU 89.A N CYS 134.A O no hydrogen 2.785 N/A TYR 92.A N CYS 88.A O no hydrogen 3.001 N/A LEU 93.A N LEU 89.A O no hydrogen 2.827 N/A ARG 94.A N LEU 90.A O no hydrogen 3.002 N/A GLU 95.A N ASN 91.A O no hydrogen 3.148 N/A GLU 95.A N TYR 92.A O no hydrogen 3.352 N/A HIS 98.A N GLU 95.A O no hydrogen 3.420 N/A HIS 98.A NE2 GLU 95.A OE1 no hydrogen 2.797 N/A ARG 99.A N MET 96.A O no hydrogen 3.276 N/A GLN 101.A N GLN 104.A OE1 no hydrogen 2.739 N/A LEU 105.A N GLN 101.A O no hydrogen 3.146 N/A LEU 106.A N THR 102.A O no hydrogen 2.929 N/A GLU 107.A N GLN 103.A O no hydrogen 2.959 N/A MET 108.A N GLN 104.A O no hydrogen 2.943 N/A CYS 109.A N LEU 105.A O no hydrogen 2.997 N/A CYS 109.A SG LEU 105.A O no hydrogen 3.466 N/A LYS 110.A N LEU 106.A O no hydrogen 2.869 N/A LYS 110.A NZ GLU 114.A OE2 no hydrogen 2.799 N/A ASP 111.A N GLU 107.A O no hydrogen 2.900 N/A VAL 112.A N MET 108.A O no hydrogen 3.068 N/A CYS 113.A N CYS 109.A O no hydrogen 2.874 N/A CYS 113.A SG PHE 243.A O no hydrogen 3.471 N/A GLU 114.A N LYS 110.A O no hydrogen 2.880 N/A ALA 115.A N ASP 111.A O no hydrogen 3.113 N/A MET 116.A N VAL 112.A O no hydrogen 2.910 N/A GLU 117.A N CYS 113.A O no hydrogen 2.839 N/A TYR 118.A N GLU 114.A O no hydrogen 2.993 N/A LEU 119.A N ALA 115.A O no hydrogen 2.976 N/A GLU 120.A N MET 116.A O no hydrogen 2.831 N/A SER 121.A N GLU 117.A O no hydrogen 2.867 N/A SER 121.A OG TYR 118.A O no hydrogen 2.773 N/A LYS 122.A N TYR 118.A O no hydrogen 3.007 N/A GLN 123.A N GLU 120.A O no hydrogen 2.866 N/A PHE 124.A N LEU 119.A O no hydrogen 2.874 N/A HIS 126.A N ASP 178.A OD2 no hydrogen 2.711 N/A HIS 126.A NE2 SER 145.A O no hydrogen 2.898 N/A ARG 127.A N ASP 178.A OD1 no hydrogen 3.135 N/A ASP 128.A N HIS 126.A ND1 no hydrogen 3.129 N/A ALA 131.A N GLU 188.A OE2 no hydrogen 2.876 N/A ARG 132.A NH2 ASP 128.A OD1 no hydrogen 2.852 N/A ASN 133.A N ALA 130.A O no hydrogen 2.885 N/A ASN 133.A ND2 ASP 128.A O no hydrogen 2.569 N/A CYS 134.A N ALA 131.A O no hydrogen 3.156 N/A CYS 134.A SG ALA 130.A O no hydrogen 3.612 N/A LEU 135.A N LYS 143.A O no hydrogen 2.944 N/A VAL 136.A N GLY 87.A O no hydrogen 2.944 N/A ASN 137.A N VAL 141.A O no hydrogen 3.038 N/A GLN 139.A N ASN 137.A OD1 no hydrogen 2.945 N/A GLN 139.A NE2 ASP 138.A OD2 no hydrogen 3.174 N/A GLY 140.A N ASN 137.A O no hydrogen 3.212 N/A VAL 141.A N ASN 137.A OD1 no hydrogen 2.809 N/A VAL 142.A N ASP 111.A OD2 no hydrogen 3.054 N/A LYS 143.A N LEU 135.A O no hydrogen 2.886 N/A LYS 143.A NZ GLU 62.A O no hydrogen 2.967 N/A LYS 143.A NZ GLU 82.A OE2 no hydrogen 2.714 N/A VAL 144.A N LYS 63.A O no hydrogen 2.927 N/A SER 145.A N ASN 133.A O no hydrogen 3.087 N/A GLY 148.A N HIS 126.A O no hydrogen 3.045 N/A LEU 149.A N ASP 146.A O no hydrogen 3.173 N/A ARG 151.A N GLY 148.A O no hydrogen 3.426 N/A ARG 151.A NE GLY 148.A O no hydrogen 3.182 N/A ARG 151.A NH1 GLU 52.A OE2 no hydrogen 3.044 N/A ARG 151.A NH2 GLU 52.A OE2 no hydrogen 3.311 N/A ARG 151.A NH2 GLY 148.A O no hydrogen 3.485 N/A TYR 152.A N LEU 149.A O no hydrogen 2.950 N/A VAL 153.A N SER 150.A O no hydrogen 3.474 N/A LEU 154.A N SER 43.A O no hydrogen 2.964 N/A VAL 160.A N PHE 158.A O no hydrogen 2.659 N/A ARG 161.A NE ASN 202.A OD1 no hydrogen 3.072 N/A ARG 161.A NH1 PRO 196.A O no hydrogen 2.949 N/A ARG 161.A NH1 TYR 197.A O no hydrogen 2.743 N/A ARG 161.A NH1 PHE 200.A O no hydrogen 3.033 N/A ARG 161.A NH2 PHE 200.A O no hydrogen 2.759 N/A TRP 162.A N PRO 159.A O no hydrogen 3.248 N/A TRP 162.A NE1 GLU 188.A OE2 no hydrogen 2.845 N/A SER 163.A N VAL 160.A O no hydrogen 3.072 N/A SER 163.A OG PRO 159.A O no hydrogen 2.678 N/A GLU 166.A N GLU 166.A OE1 no hydrogen 2.792 N/A LEU 168.A N PRO 164.A O no hydrogen 3.207 N/A MET 169.A N PRO 165.A O no hydrogen 2.884 N/A TYR 170.A N GLU 166.A O no hydrogen 2.929 N/A SER 171.A N VAL 167.A O no hydrogen 2.859 N/A LYS 172.A N GLU 166.A O no hydrogen 3.227 N/A SER 174.A N SER 177.A OG no hydrogen 2.902 N/A LYS 176.A N SER 174.A OG no hydrogen 2.994 N/A LYS 176.A NZ ARG 240.A O no hydrogen 2.874 N/A SER 177.A N SER 174.A O no hydrogen 3.120 N/A SER 177.A OG SER 174.A O no hydrogen 2.482 N/A ASP 178.A N SER 174.A O no hydrogen 3.421 N/A ILE 179.A N SER 175.A O no hydrogen 2.935 N/A TRP 180.A N LYS 176.A O no hydrogen 2.943 N/A ALA 181.A N SER 177.A O no hydrogen 2.971 N/A PHE 182.A N ASP 178.A O no hydrogen 2.895 N/A GLY 183.A N ILE 179.A O no hydrogen 2.970 N/A VAL 184.A N TRP 180.A O no hydrogen 3.028 N/A LEU 185.A N ALA 181.A O no hydrogen 2.856 N/A MET 186.A N PHE 182.A O no hydrogen 2.897 N/A TRP 187.A N GLY 183.A O no hydrogen 3.023 N/A TRP 187.A NE1 TYR 216.A O no hydrogen 2.947 N/A GLU 188.A N VAL 184.A O no hydrogen 2.925 N/A ILE 189.A N LEU 185.A O no hydrogen 2.890 N/A TYR 190.A N MET 186.A O no hydrogen 2.943 N/A SER 191.A N TRP 187.A O no hydrogen 2.837 N/A SER 191.A OG TRP 187.A O no hydrogen 2.933 N/A LEU 192.A N ILE 189.A O no hydrogen 3.078 N/A GLY 193.A N GLU 188.A O no hydrogen 2.825 N/A LYS 194.A N SER 191.A O no hydrogen 3.387 N/A LYS 194.A NZ GLU 198.A OE1 no hydrogen 3.442 N/A LYS 194.A NZ GLU 198.A OE2 no hydrogen 3.452 N/A PHE 200.A N TYR 197.A O no hydrogen 2.848 N/A THR 201.A N GLU 204.A OE1 no hydrogen 2.888 N/A THR 201.A OG1 GLU 204.A OE1 no hydrogen 3.231 N/A GLU 204.A N THR 201.A OG1 no hydrogen 3.050 N/A THR 205.A N THR 201.A O no hydrogen 2.834 N/A THR 205.A OG1 THR 201.A O no hydrogen 2.834 N/A ALA 206.A N ASN 202.A O no hydrogen 2.889 N/A GLU 207.A N SER 203.A O no hydrogen 2.992 N/A HIS 208.A N GLU 204.A O no hydrogen 2.836 N/A ILE 209.A N THR 205.A O no hydrogen 2.874 N/A ALA 210.A N ALA 206.A O no hydrogen 2.919 N/A GLN 211.A N GLU 207.A O no hydrogen 3.096 N/A GLY 212.A N ILE 209.A O no hydrogen 2.946 N/A LEU 213.A N HIS 208.A O no hydrogen 3.158 N/A ARG 214.A NE TRP 233.A O no hydrogen 2.891 N/A ARG 214.A NH1 ILE 209.A O no hydrogen 3.222 N/A ARG 214.A NH1 LEU 213.A O no hydrogen 3.024 N/A ARG 214.A NH2 TRP 233.A O no hydrogen 3.036 N/A ARG 217.A NE ALA 221.A O no hydrogen 2.641 N/A ARG 217.A NH2 ALA 221.A O no hydrogen 3.139 N/A ALA 221.A N PRO 218.A O no hydrogen 3.130 N/A SER 222.A OG GLU 257.A OE1 no hydrogen 3.147 N/A VAL 225.A N SER 222.A OG no hydrogen 3.399 N/A TYR 226.A N SER 222.A O no hydrogen 2.942 N/A THR 227.A N GLU 223.A O no hydrogen 2.894 N/A THR 227.A OG1 GLU 223.A O no hydrogen 2.663 N/A ILE 228.A N LYS 224.A O no hydrogen 2.990 N/A MET 229.A N VAL 225.A O no hydrogen 2.995 N/A TYR 230.A N TYR 226.A O no hydrogen 2.833 N/A SER 231.A N THR 227.A O no hydrogen 2.959 N/A SER 231.A N ILE 228.A O no hydrogen 3.250 N/A SER 231.A OG ILE 228.A O no hydrogen 2.624 N/A CYS 232.A N MET 229.A O no hydrogen 3.142 N/A CYS 232.A SG ILE 228.A O no hydrogen 3.723 N/A TRP 233.A N TYR 230.A O no hydrogen 3.062 N/A GLU 239.A N LYS 236.A O no hydrogen 3.059 N/A ARG 240.A N ALA 237.A O no hydrogen 2.959 N/A ARG 240.A NE HIS 234.A O no hydrogen 2.669 N/A ARG 240.A NH1 GLU 166.A OE2 no hydrogen 2.866 N/A ARG 240.A NH1 LYS 176.A O no hydrogen 3.182 N/A ARG 240.A NH2 GLU 166.A OE1 no hydrogen 2.875 N/A ARG 240.A NH2 GLU 166.A OE2 no hydrogen 3.414 N/A ARG 240.A NH2 HIS 234.A O no hydrogen 3.133 N/A ARG 240.A NH2 GLU 235.A O no hydrogen 3.436 N/A PHE 243.A N GLU 120.A OE1 no hydrogen 3.229 N/A PHE 243.A N GLU 120.A OE2 no hydrogen 3.313 N/A LYS 244.A NZ GLU 117.A OE2 no hydrogen 2.922 N/A ILE 245.A N THR 242.A OG1 no hydrogen 3.191 N/A LEU 246.A N THR 242.A O no hydrogen 2.971 N/A LEU 247.A N PHE 243.A O no hydrogen 2.851 N/A SER 248.A N LYS 244.A O no hydrogen 2.985 N/A ASN 249.A N ILE 245.A O no hydrogen 2.920 N/A ILE 250.A N LEU 246.A O no hydrogen 2.884 N/A LEU 251.A N LEU 247.A O no hydrogen 2.930 N/A ASP 252.A N SER 248.A O no hydrogen 2.915 N/A VAL 253.A N ASN 249.A O no hydrogen 2.951 N/A MET 254.A N ILE 250.A O no hydrogen 2.888 N/A ASP 255.A N LEU 251.A O no hydrogen 2.946 N/A GLU 256.A N ASP 252.A O no hydrogen 2.893 N/A GLU 257.A N VAL 253.A O no hydrogen 2.769 N/A