Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 7r9n_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ASP 5.A N ASP 3.A OD2 no hydrogen 2.846 N/A ILE 6.A N ASP 3.A O no hydrogen 3.483 N/A PHE 7.A N SER 78.A O no hydrogen 2.745 N/A ARG 12.A N.A ASP 10.A OD1 no hydrogen 3.024 N/A ARG 12.A N.B ASP 10.A OD1 no hydrogen 3.017 N/A ARG 12.A NE.A ASP 10.A OD1 no hydrogen 2.641 N/A ASP 13.A N ASP 10.A O no hydrogen 3.011 N/A HIS 14.A N PRO 11.A O no hydrogen 2.937 N/A HIS 14.A ND1 TYR 79.A OH no hydrogen 2.920 N/A TYR 15.A N PRO 11.A O no hydrogen 2.923 N/A ASP 16.A N ARG 33.A O no hydrogen 2.905 N/A LEU 18.A N LYS 31.A O no hydrogen 2.778 N/A GLN 19.A N LYS 31.A O no hydrogen 3.246 N/A ARG 20.A NE GLU 28.A OE2 no hydrogen 2.495 N/A LEU 21.A N VAL 29.A O no hydrogen 2.763 N/A GLY 24.A N GLY 27.A O no hydrogen 2.703 N/A GLY 27.A N GLY 24.A O no hydrogen 3.076 N/A GLU 28.A N MET 45.A O no hydrogen 2.916 N/A VAL 29.A N GLY 22.A O no hydrogen 3.016 N/A PHE 30.A N LEU 43.A O no hydrogen 2.791 N/A LYS 31.A N GLN 19.A O no hydrogen 2.849 N/A ALA 32.A N VAL 41.A O no hydrogen 2.943 N/A ARG 33.A N ASP 16.A O no hydrogen 2.948 N/A ARG 33.A NH1 GLY 38.A O no hydrogen 2.753 N/A ASP 34.A N ASP 39.A O no hydrogen 2.765 N/A LYS 35.A N HIS 14.A O no hydrogen 2.871 N/A LYS 35.A NZ ARG 12.A O.A no hydrogen 2.978 N/A LYS 35.A NZ ARG 12.A O.B no hydrogen 2.981 N/A VAL 36.A N ASP 34.A OD1 no hydrogen 2.826 N/A SER 37.A N ASP 34.A OD1 no hydrogen 2.966 N/A GLY 38.A N ASP 34.A O no hydrogen 2.865 N/A ASP 39.A N SER 37.A OG no hydrogen 3.195 N/A VAL 41.A N ALA 32.A O no hydrogen 2.841 N/A ALA 42.A N MET 89.A O no hydrogen 2.834 N/A LEU 43.A N PHE 30.A O no hydrogen 2.869 N/A LYS 44.A N ILE 87.A O no hydrogen 2.883 N/A LYS 44.A NZ GLU 60.A OE1 no hydrogen 2.990 N/A LYS 44.A NZ GLU 60.A OE2 no hydrogen 3.352 N/A MET 45.A N GLU 28.A O no hydrogen 2.698 N/A VAL 46.A N LEU 85.A O no hydrogen 2.829 N/A MET 48.A N GLN 83.A O no hydrogen 2.931 N/A GLU 49.A N ASP 52.A OD2 no hydrogen 3.261 N/A ASP 52.A N GLU 49.A O no hydrogen 3.079 N/A SER 55.A N ASP 53.A OD1 no hydrogen 3.226 N/A SER 55.A OG ASP 53.A OD1 no hydrogen 2.956 N/A SER 55.A OG ASP 53.A OD2 no hydrogen 2.846 N/A GLN 58.A N VAL 54.A O no hydrogen 2.770 N/A GLN 58.A NE2 VAL 1.A O no hydrogen 2.818 N/A GLN 58.A NE2 VAL 2.A O no hydrogen 3.382 N/A LYS 59.A N SER 55.A O no hydrogen 2.996 N/A GLU 60.A N THR 56.A O no hydrogen 2.954 N/A ILE 61.A N LEU 57.A O no hydrogen 3.007 N/A LEU 62.A N GLN 58.A O no hydrogen 3.003 N/A ILE 63.A N LYS 59.A O no hydrogen 2.998 N/A LEU 64.A N GLU 60.A O no hydrogen 3.058 N/A LYS 65.A N ILE 61.A O no hydrogen 2.840 N/A LYS 65.A NZ ASP 3.A OD1 no hydrogen 2.873 N/A LYS 65.A NZ ASP 3.A OD2 no hydrogen 3.276 N/A LYS 65.A NZ ASP 5.A OD2 no hydrogen 2.876 N/A THR 66.A N ILE 63.A O no hydrogen 3.358 N/A THR 66.A OG1 LEU 62.A O no hydrogen 2.867 N/A THR 66.A OG1 ILE 63.A O no hydrogen 3.291 N/A CYS 67.A N LEU 64.A O no hydrogen 3.311 N/A CYS 67.A SG ILE 63.A O no hydrogen 3.329 N/A CYS 67.A SG GLN 129.A OE1 no hydrogen 3.770 N/A ARG 68.A N TYR 125.A OH no hydrogen 2.868 N/A ASN 71.A N HIS 69.A ND1 no hydrogen 2.927 N/A ASN 71.A ND2 GLU 118.A OE1 no hydrogen 3.009 N/A ASN 71.A ND2 VAL 149.A O no hydrogen 2.993 N/A ILE 72.A N HIS 69.A O no hydrogen 2.981 N/A VAL 73.A N.A LEU 151.A O no hydrogen 3.069 N/A VAL 73.A N.B LEU 151.A O no hydrogen 3.069 N/A ALA 74.A N GLU 90.A OE1 no hydrogen 3.033 N/A TYR 75.A OH SER 78.A OG no hydrogen 2.756 N/A HIS 76.A N CYS 88.A O no hydrogen 2.873 N/A SER 78.A OG TYR 75.A OH no hydrogen 2.756 N/A TYR 79.A N TRP 86.A O no hydrogen 2.836 N/A TYR 79.A OH HIS 14.A ND1 no hydrogen 2.920 N/A LEU 80.A N PHE 7.A O no hydrogen 2.917 N/A TRP 81.A N LYS 84.A O no hydrogen 2.983 N/A LYS 84.A N TRP 81.A O no hydrogen 3.086 N/A LEU 85.A N VAL 46.A O no hydrogen 2.800 N/A TRP 86.A N TYR 79.A O no hydrogen 2.765 N/A ILE 87.A N LYS 44.A O no hydrogen 2.786 N/A CYS 88.A N GLY 77.A O no hydrogen 2.844 N/A CYS 88.A SG TYR 15.A OH no hydrogen 3.380 N/A MET 89.A N ALA 42.A O no hydrogen 2.845 N/A GLU 90.A N ALA 74.A O no hydrogen 2.875 N/A ALA 94.A N ILE 143.A O no hydrogen 3.022 N/A GLY 95.A N CYS 92.A O no hydrogen 3.112 N/A SER 96.A N ASP 99.A OD2 no hydrogen 2.936 N/A LEU 97.A N ILE 141.A O no hydrogen 2.927 N/A GLN 98.A N GLY 138.A O no hydrogen 3.362 N/A GLN 98.A NE2 TYR 101.A OH no hydrogen 3.338 N/A ASP 99.A N SER 96.A OG no hydrogen 2.991 N/A ILE 100.A N SER 96.A O no hydrogen 3.070 N/A TYR 101.A N LEU 97.A O no hydrogen 2.806 N/A TYR 101.A OH GLU 205.A OE2 no hydrogen 2.562 N/A GLN 102.A N GLN 98.A O no hydrogen 3.096 N/A VAL 103.A N ILE 100.A O no hydrogen 2.939 N/A THR 104.A N ILE 100.A O no hydrogen 2.925 N/A THR 104.A OG1 ILE 100.A O no hydrogen 3.267 N/A THR 104.A OG1 GLY 105.A O no hydrogen 2.914 N/A GLY 105.A N TYR 101.A O no hydrogen 2.889 N/A LEU 107.A N LEU 206.A O no hydrogen 3.083 N/A SER 108.A N GLN 111.A OE1 no hydrogen 2.946 N/A GLN 111.A N SER 108.A OG no hydrogen 3.036 N/A GLN 111.A NE2 LEU 281.A O no hydrogen 3.029 N/A ILE 112.A N SER 108.A O no hydrogen 2.925 N/A SER 113.A N GLU 109.A O no hydrogen 2.858 N/A SER 113.A OG GLU 109.A O no hydrogen 2.773 N/A TYR 114.A N LEU 110.A O no hydrogen 3.005 N/A TYR 114.A OH GLY 147.A O no hydrogen 2.949 N/A VAL 115.A N GLN 111.A O no hydrogen 3.006 N/A CYS 116.A N ILE 112.A O no hydrogen 2.796 N/A CYS 116.A SG ILE 112.A O no hydrogen 3.356 N/A ARG 117.A N SER 113.A O no hydrogen 2.960 N/A ARG 117.A NE GLU 118.A OE2 no hydrogen 2.994 N/A ARG 117.A NH1 LEU 277.A O no hydrogen 2.986 N/A ARG 117.A NH2 GLU 118.A OE2 no hydrogen 2.896 N/A ARG 117.A NH2 LEU 277.A O no hydrogen 3.245 N/A GLU 118.A N TYR 114.A O no hydrogen 2.994 N/A VAL 119.A N VAL 115.A O no hydrogen 2.835 N/A LEU 120.A N CYS 116.A O no hydrogen 2.870 N/A GLN 121.A N ARG 117.A O no hydrogen 2.933 N/A GLN 121.A NE2 ASN 71.A OD1 no hydrogen 2.999 N/A GLN 121.A NE2 GLU 118.A OE1 no hydrogen 3.326 N/A GLN 121.A NE2 GLU 118.A OE2 no hydrogen 3.116 N/A GLY 122.A N GLU 118.A O no hydrogen 3.086 N/A LEU 123.A N VAL 119.A O no hydrogen 2.769 N/A ALA 124.A N LEU 120.A O no hydrogen 2.820 N/A TYR 125.A N GLN 121.A O no hydrogen 3.165 N/A LEU 126.A N GLY 122.A O no hydrogen 2.953 N/A HIS 127.A N LEU 123.A O no hydrogen 2.776 N/A HIS 127.A NE2 ASP 195.A OD2 no hydrogen 2.893 N/A SER 128.A N ALA 124.A O no hydrogen 3.008 N/A SER 128.A OG TYR 125.A O no hydrogen 2.682 N/A GLN 129.A N TYR 125.A O no hydrogen 3.260 N/A GLN 129.A N LEU 126.A O no hydrogen 2.957 N/A GLN 129.A NE2 THR 66.A O no hydrogen 2.930 N/A LYS 130.A N HIS 127.A O no hydrogen 2.886 N/A LYS 131.A N LEU 126.A O no hydrogen 2.975 N/A LYS 131.A NZ ILE 63.A O no hydrogen 3.250 N/A LYS 131.A NZ THR 66.A OG1 no hydrogen 2.570 N/A LYS 131.A NZ GLN 129.A OE1 no hydrogen 2.638 N/A HIS 133.A N ASP 195.A OD2 no hydrogen 2.929 N/A HIS 133.A NE2 ALA 152.A O no hydrogen 2.888 N/A ARG 134.A N ASP 195.A OD1 no hydrogen 2.828 N/A ARG 134.A NE ARG 134.A O no hydrogen 2.737 N/A ARG 134.A NH1 TYR 190.A OH no hydrogen 2.766 N/A ASP 135.A N HIS 133.A ND1 no hydrogen 2.964 N/A GLY 138.A N GLU 205.A OE1 no hydrogen 2.914 N/A ASN 140.A N LYS 137.A O no hydrogen 2.981 N/A ASN 140.A ND2 ASP 135.A O no hydrogen 2.807 N/A ASN 140.A ND2 ASP 135.A OD2 no hydrogen 2.945 N/A ILE 141.A N GLY 138.A O no hydrogen 3.368 N/A LEU 142.A N ARG 150.A O.A no hydrogen 2.768 N/A LEU 142.A N ARG 150.A O.B no hydrogen 2.812 N/A ILE 143.A N GLY 95.A O no hydrogen 2.849 N/A ASN 144.A N GLU 148.A O no hydrogen 3.085 N/A ASN 144.A ND2 GLU 148.A OE1 no hydrogen 2.855 N/A ALA 146.A N ASN 144.A OD1 no hydrogen 2.976 N/A GLY 147.A N ASN 144.A O no hydrogen 2.914 N/A GLU 148.A N ASN 144.A OD1 no hydrogen 2.938 N/A ARG 150.A N.A LEU 142.A O no hydrogen 2.885 N/A ARG 150.A N.B LEU 142.A O no hydrogen 2.890 N/A ARG 150.A NE.A GLU 90.A OE1 no hydrogen 3.395 N/A ARG 150.A NE.A GLU 90.A OE2 no hydrogen 2.807 N/A ARG 150.A NE.B GLU 90.A OE2 no hydrogen 2.815 N/A ARG 150.A NH1.A VAL 149.A O no hydrogen 3.005 N/A ARG 150.A NH1.B VAL 149.A O no hydrogen 3.004 N/A LEU 151.A N ASN 71.A O no hydrogen 2.795 N/A ALA 152.A N ASN 140.A O no hydrogen 3.079 N/A GLY 155.A N ASP 153.A OD1 no hydrogen 3.346 N/A SER 157.A OG ILE 132.A O no hydrogen 2.716 N/A ALA 158.A N PHE 154.A O no hydrogen 2.870 N/A GLN 159.A N GLY 155.A O no hydrogen 2.870 N/A ILE 160.A N ILE 156.A O no hydrogen 2.925 N/A GLY 161.A N SER 157.A O no hydrogen 2.889 N/A ALA 162.A N ALA 158.A O no hydrogen 2.841 N/A GLU 163.A N GLN 159.A O no hydrogen 2.961 N/A LEU 164.A N ILE 160.A O no hydrogen 2.796 N/A ALA 165.A N GLY 161.A O no hydrogen 2.972 N/A ARG 166.A N ALA 162.A O no hydrogen 3.040 N/A ARG 167.A N GLU 163.A O no hydrogen 2.833 N/A LEU 168.A N LEU 164.A O no hydrogen 3.090 N/A GLU 169.A N ALA 165.A O no hydrogen 3.043 N/A PHE 170.A N ARG 166.A O no hydrogen 3.171 N/A PHE 170.A N ARG 167.A O no hydrogen 3.271 N/A ILE 171.A N LEU 168.A O no hydrogen 3.420 N/A MET 177.A N PRO 174.A O no hydrogen 2.992 N/A GLU 180.A N GLU 180.A OE1 no hydrogen 2.856 N/A ALA 182.A N ALA 178.A O no hydrogen 3.133 N/A ALA 183.A N PRO 179.A O no hydrogen 2.821 N/A VAL 184.A N GLU 180.A O no hydrogen 3.071 N/A ALA 185.A N VAL 181.A O no hydrogen 3.097 N/A LEU 186.A N ALA 182.A O no hydrogen 2.918 N/A LYS 187.A N ALA 183.A O no hydrogen 2.785 N/A GLY 188.A N VAL 184.A O no hydrogen 2.883 N/A GLU 192.A N GLU 192.A OE1 no hydrogen 2.732 N/A LEU 193.A N ASN 191.A OD1 no hydrogen 2.991 N/A CYS 194.A N ASN 191.A O no hydrogen 3.141 N/A CYS 194.A SG ASN 191.A O no hydrogen 3.296 N/A ASP 195.A N GLU 192.A O no hydrogen 2.982 N/A ILE 196.A N LEU 193.A O no hydrogen 3.022 N/A TRP 197.A N LEU 193.A O no hydrogen 3.411 N/A SER 198.A N CYS 194.A O no hydrogen 3.087 N/A SER 198.A OG CYS 194.A O no hydrogen 3.158 N/A LEU 199.A N ASP 195.A O no hydrogen 2.980 N/A GLY 200.A N ILE 196.A O no hydrogen 3.140 N/A ILE 201.A N TRP 197.A O no hydrogen 3.040 N/A THR 202.A N SER 198.A O no hydrogen 2.873 N/A THR 202.A OG1 SER 198.A O no hydrogen 2.817 N/A ALA 203.A N LEU 199.A O no hydrogen 2.873 N/A ILE 204.A N GLY 200.A O no hydrogen 3.210 N/A GLU 205.A N ILE 201.A O no hydrogen 2.842 N/A LEU 206.A N THR 202.A O no hydrogen 2.823 N/A ALA 207.A N ALA 203.A O no hydrogen 3.053 N/A GLU 208.A N ILE 204.A O no hydrogen 2.801 N/A LEU 209.A N GLU 205.A O no hydrogen 2.729 N/A PHE 214.A N PRO 211.A O no hydrogen 3.262 N/A VAL 216.A N LEU 213.A O no hydrogen 2.945 N/A LEU 219.A N HIS 217.A ND1 no hydrogen 3.093 N/A VAL 221.A N HIS 217.A O no hydrogen 3.018 N/A LEU 222.A N PRO 218.A O no hydrogen 2.996 N/A PHE 223.A N LEU 219.A O no hydrogen 2.954 N/A LEU 224.A N ARG 220.A O no hydrogen 2.878 N/A MET 225.A N VAL 221.A O no hydrogen 3.113 N/A THR 226.A N PHE 223.A O no hydrogen 3.018 N/A THR 226.A OG1 PHE 223.A O no hydrogen 2.806 N/A LYS 227.A N LEU 224.A O no hydrogen 3.235 N/A TYR 230.A N LYS 227.A O no hydrogen 3.200 N/A GLN 231.A NE2 GLY 229.A O no hydrogen 2.798 N/A LYS 236.A N GLU 208.A OE2 no hydrogen 2.720 N/A LYS 238.A NZ LEU 235.A O no hydrogen 2.793 N/A SER 242.A N GLU 109.A OE1 no hydrogen 2.883 N/A SER 242.A OG GLU 109.A OE1 no hydrogen 3.564 N/A SER 242.A OG GLU 109.A OE2 no hydrogen 2.510 N/A PHE 245.A N SER 242.A OG no hydrogen 3.143 N/A HIS 246.A N SER 242.A O no hydrogen 3.000 N/A HIS 246.A NE2 LYS 238.A O no hydrogen 2.887 N/A ASN 247.A N ALA 243.A O no hydrogen 2.873 N/A PHE 248.A N ALA 244.A O no hydrogen 2.897 N/A ILE 249.A N PHE 245.A O no hydrogen 3.026 N/A LYS 250.A N HIS 246.A O no hydrogen 2.916 N/A VAL 251.A N ASN 247.A O no hydrogen 2.915 N/A THR 252.A N PHE 248.A O no hydrogen 2.987 N/A THR 252.A OG1 PHE 248.A O no hydrogen 2.904 N/A THR 252.A OG1 ILE 249.A O no hydrogen 3.310 N/A LEU 253.A N ILE 249.A O no hydrogen 2.999 N/A THR 254.A N VAL 251.A O no hydrogen 3.319 N/A THR 254.A OG1 VAL 251.A O no hydrogen 2.663 N/A LYS 255.A NZ TYR 230.A O no hydrogen 2.958 N/A LYS 259.A N SER 256.A O no hydrogen 3.047 N/A ARG 260.A N PRO 257.A O no hydrogen 3.290 N/A ARG 260.A NE THR 254.A O no hydrogen 2.846 N/A ARG 260.A NH1 LEU 193.A O no hydrogen 2.980 N/A ARG 260.A NH2 THR 254.A O no hydrogen 2.971 N/A ARG 260.A NH2 LYS 255.A O no hydrogen 3.092 N/A LYS 265.A N SER 262.A OG no hydrogen 3.043 N/A MET 266.A N SER 262.A O no hydrogen 2.877 N/A LEU 267.A N ALA 263.A O no hydrogen 2.989 N/A SER 268.A N LYS 265.A O no hydrogen 3.003 N/A SER 268.A OG LYS 265.A O no hydrogen 2.651 N/A HIS 269.A N MET 266.A O no hydrogen 2.914 N/A HIS 269.A NE2 ASN 247.A OD1 no hydrogen 2.793 N/A LEU 271.A N HIS 269.A ND1 no hydrogen 2.976 N/A VAL 272.A N HIS 269.A O no hydrogen 3.115 N/A SER 273.A N.A HIS 269.A O no hydrogen 2.953 N/A SER 273.A N.B HIS 269.A O no hydrogen 2.975 N/A SER 273.A N.B GLN 270.A O no hydrogen 3.367 N/A SER 273.A OG.A LEU 267.A O no hydrogen 3.060 N/A SER 273.A OG.A HIS 269.A O no hydrogen 2.996 N/A SER 273.A OG.B HIS 269.A O no hydrogen 2.946 N/A SER 273.A OG.B GLN 270.A O no hydrogen 3.501 N/A GLN 274.A NE2 LEU 271.A O no hydrogen 2.909 N/A ARG 279.A NH1 ALA 146.A O no hydrogen 2.917 N/A GLY 280.A N ASN 278.A OD1 no hydrogen 2.912 N/A LEU 281.A N ASN 278.A O no hydrogen 3.076 N/A ILE 282.A N ARG 279.A O no hydrogen 3.030 N/A LEU 283.A N ARG 279.A O no hydrogen 2.909 N/A ASP 284.A N GLY 280.A O no hydrogen 2.904 N/A LEU 285.A N LEU 281.A O no hydrogen 3.297 N/A LEU 286.A N ILE 282.A O no hydrogen 2.831 N/A ASP 287.A N LEU 283.A O no hydrogen 2.920 N/A LYS 288.A N ASP 284.A O no hydrogen 3.095 N/A LYS 288.A NZ THR 104.A O no hydrogen 2.946 N/A LEU 289.A N LEU 285.A O no hydrogen 2.957 N/A LYS 290.A N LEU 286.A O no hydrogen 3.230 N/A LYS 290.A N ASP 287.A O no hydrogen 3.186 N/A LYS 290.A NZ LEU 286.A O no hydrogen 3.562 N/A ASN 291.A N ASP 287.A O no hydrogen 2.674 N/A