Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8hmt_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): THR 2.A OG1 HIS 63.A ND1 no hydrogen 2.938 N/A CYS 3.A N TYR 74.A O no hydrogen 2.940 N/A ILE 5.A N VAL 76.A O no hydrogen 2.809 N/A LYS 8.A NZ ASP 9.A OD1 no hydrogen 3.273 N/A LYS 8.A NZ ASP 9.A OD2 no hydrogen 2.845 N/A ASP 9.A N GLY 6.A O no hydrogen 3.004 N/A LEU 10.A N GLU 7.A O no hydrogen 2.920 N/A ARG 11.A N GLU 25.A O no hydrogen 2.794 N/A ARG 11.A NH1 ASP 27.A OD1 no hydrogen 3.453 N/A ARG 11.A NH1 ASP 27.A OD2 no hydrogen 2.502 N/A ARG 11.A NH2 ASP 27.A OD1 no hydrogen 2.843 N/A LEU 13.A N ARG 23.A O no hydrogen 2.898 N/A GLU 14.A N GLU 14.A OE1 no hydrogen 2.871 N/A LEU 16.A N VAL 21.A O no hydrogen 2.874 N/A GLY 17.A N VAL 21.A O no hydrogen 3.417 N/A VAL 20.A N CYS 40.A O no hydrogen 3.335 N/A VAL 21.A N GLY 17.A O no hydrogen 3.400 N/A ARG 22.A N VAL 38.A O no hydrogen 2.870 N/A ARG 22.A NE LEU 13.A O no hydrogen 3.033 N/A ARG 22.A NH2 LEU 13.A O no hydrogen 2.727 N/A ARG 23.A N GLU 14.A O no hydrogen 2.896 N/A ARG 23.A NH1 GLU 14.A OE2 no hydrogen 3.541 N/A GLY 24.A N VAL 36.A O no hydrogen 2.925 N/A GLU 25.A N ARG 11.A O no hydrogen 2.751 N/A TRP 26.A N VAL 34.A O no hydrogen 3.012 N/A ASP 27.A N ASP 9.A O no hydrogen 2.865 N/A ALA 28.A N LYS 32.A O no hydrogen 2.983 N/A GLY 31.A N ALA 28.A O no hydrogen 3.037 N/A THR 33.A OG1 ASP 27.A OD1 no hydrogen 3.215 N/A VAL 34.A N TRP 26.A O no hydrogen 2.956 N/A VAL 36.A N GLY 24.A O no hydrogen 3.229 N/A ALA 37.A N THR 86.A O no hydrogen 3.327 N/A VAL 38.A N ARG 22.A O no hydrogen 2.675 N/A LYS 39.A N MET 84.A O no hydrogen 2.823 N/A CYS 40.A N VAL 20.A O no hydrogen 3.286 N/A CYS 40.A SG VAL 20.A O no hydrogen 3.927 N/A GLN 48.A N VAL 45.A O no hydrogen 2.800 N/A GLU 50.A N SER 47.A O no hydrogen 2.838 N/A ALA 51.A N SER 47.A O no hydrogen 2.821 N/A ASP 53.A N GLN 48.A O no hydrogen 3.242 N/A ASP 54.A N GLU 50.A O no hydrogen 3.096 N/A PHE 55.A N ALA 51.A O no hydrogen 2.974 N/A ILE 56.A N MET 52.A O no hydrogen 2.877 N/A ARG 57.A N ASP 53.A O no hydrogen 3.021 N/A GLU 58.A N ASP 54.A O no hydrogen 2.948 N/A VAL 59.A N PHE 55.A O no hydrogen 3.071 N/A ASN 60.A N ILE 56.A O no hydrogen 2.975 N/A ALA 61.A N ARG 57.A O no hydrogen 2.948 N/A MET 62.A N GLU 58.A O no hydrogen 3.020 N/A HIS 63.A N VAL 59.A O no hydrogen 3.032 N/A HIS 63.A ND1 THR 2.A OG1 no hydrogen 2.938 N/A SER 64.A N ALA 61.A O no hydrogen 2.708 N/A SER 64.A OG ALA 61.A O no hydrogen 2.549 N/A LEU 65.A N MET 62.A O no hydrogen 3.442 N/A ASP 66.A N TYR 123.A OH no hydrogen 3.277 N/A ASN 69.A N HIS 67.A ND1 no hydrogen 3.039 N/A ASN 69.A ND2 VAL 147.A O.A no hydrogen 2.999 N/A ASN 69.A ND2 VAL 147.A O.B no hydrogen 3.005 N/A LEU 70.A N HIS 67.A O no hydrogen 2.741 N/A ILE 71.A N ILE 149.A O no hydrogen 3.252 N/A ARG 72.A N GLU 87.A OE1 no hydrogen 3.357 N/A TYR 74.A N VAL 85.A O no hydrogen 2.627 N/A GLY 75.A N VAL 85.A O no hydrogen 3.168 N/A VAL 76.A N CYS 3.A O no hydrogen 3.052 N/A VAL 77.A N LYS 83.A O no hydrogen 2.863 N/A LYS 83.A N VAL 77.A O no hydrogen 3.024 N/A LYS 83.A NZ PRO 81.A O no hydrogen 2.768 N/A MET 84.A N LYS 39.A O no hydrogen 3.118 N/A VAL 85.A N GLY 75.A O no hydrogen 2.963 N/A THR 86.A N ALA 37.A O no hydrogen 2.959 N/A THR 86.A OG1 GLU 87.A O no hydrogen 3.053 N/A GLU 87.A N ARG 72.A O no hydrogen 2.864 N/A LEU 91.A N LEU 141.A O no hydrogen 3.174 N/A LEU 94.A N LEU 139.A O no hydrogen 2.581 N/A LEU 95.A N ALA 136.A O no hydrogen 3.258 N/A ARG 97.A N SER 93.A O no hydrogen 3.235 N/A LEU 98.A N LEU 94.A O no hydrogen 2.852 N/A ARG 99.A N ASP 96.A O no hydrogen 2.959 N/A ARG 99.A NE GLY 208.A O no hydrogen 3.084 N/A ARG 99.A NH2 GLY 208.A O no hydrogen 3.342 N/A LYS 100.A N ASP 96.A O no hydrogen 3.095 N/A HIS 101.A N ARG 97.A O no hydrogen 3.273 N/A GLN 102.A NE2 ARG 99.A O no hydrogen 3.093 N/A LEU 110.A N LEU 106.A O no hydrogen 3.337 N/A SER 111.A N LEU 107.A O no hydrogen 2.722 N/A SER 111.A OG LEU 107.A O no hydrogen 3.027 N/A SER 111.A OG GLN 270.A O no hydrogen 3.208 N/A ARG 112.A N GLY 108.A O no hydrogen 2.756 N/A TYR 113.A N THR 109.A O no hydrogen 2.732 N/A TYR 113.A OH ARG 144.A O no hydrogen 2.541 N/A ALA 114.A N LEU 110.A O no hydrogen 3.060 N/A VAL 115.A N SER 111.A O no hydrogen 2.981 N/A GLN 116.A N ARG 112.A O no hydrogen 3.168 N/A GLN 116.A NE2 ASP 145.A O no hydrogen 2.952 N/A VAL 117.A N TYR 113.A O no hydrogen 2.896 N/A ALA 118.A N ALA 114.A O no hydrogen 2.972 N/A GLU 119.A N VAL 115.A O no hydrogen 2.930 N/A GLY 120.A N GLN 116.A O no hydrogen 3.150 N/A MET 121.A N VAL 117.A O no hydrogen 3.137 N/A GLY 122.A N ALA 118.A O no hydrogen 2.867 N/A TYR 123.A N GLU 119.A O no hydrogen 2.978 N/A LEU 124.A N GLY 120.A O no hydrogen 2.929 N/A GLU 125.A N MET 121.A O no hydrogen 2.741 N/A SER 126.A N GLY 122.A O no hydrogen 2.811 N/A LYS 127.A N TYR 123.A O no hydrogen 3.092 N/A LYS 127.A N LEU 124.A O no hydrogen 2.750 N/A ARG 128.A N GLU 125.A O no hydrogen 3.331 N/A ARG 128.A NH2 ASP 162.A O no hydrogen 2.975 N/A PHE 129.A N LEU 124.A O no hydrogen 3.127 N/A ILE 130.A N ARG 156.A O no hydrogen 3.312 N/A HIS 131.A N ASP 193.A OD2 no hydrogen 2.818 N/A HIS 131.A NE2 ASP 151.A O no hydrogen 2.597 N/A ARG 132.A N ASP 193.A OD1 no hydrogen 3.105 N/A ARG 132.A NE LEU 154.A O no hydrogen 2.670 N/A ARG 132.A NH2 LEU 154.A O no hydrogen 3.013 N/A ASP 133.A N HIS 131.A ND1 no hydrogen 3.098 N/A ALA 136.A N GLU 203.A OE1 no hydrogen 3.308 N/A ARG 137.A NH2 ASP 133.A OD1 no hydrogen 3.047 N/A ASN 138.A N ALA 135.A O no hydrogen 3.157 N/A ASN 138.A ND2 ASP 133.A O no hydrogen 2.788 N/A ASN 138.A ND2 ASP 133.A OD2 no hydrogen 2.578 N/A LEU 139.A N ALA 136.A O no hydrogen 3.306 N/A LEU 140.A N LYS 148.A O no hydrogen 3.007 N/A LEU 141.A N GLY 92.A O no hydrogen 3.056 N/A ALA 142.A N LEU 146.A O no hydrogen 3.032 N/A ASP 145.A N THR 143.A OG1 no hydrogen 3.003 N/A VAL 147.A N.A GLN 116.A OE1 no hydrogen 2.627 N/A VAL 147.A N.B GLN 116.A OE1 no hydrogen 2.612 N/A LYS 148.A N LEU 140.A O no hydrogen 2.883 N/A LYS 148.A NZ ARG 68.A O no hydrogen 3.116 N/A LYS 148.A NZ GLU 87.A OE1 no hydrogen 3.462 N/A LYS 148.A NZ GLU 87.A OE2 no hydrogen 2.608 N/A ILE 149.A N ASN 69.A O no hydrogen 2.838 N/A GLY 150.A N ASN 138.A O no hydrogen 2.778 N/A MET 155.A N PHE 152.A O no hydrogen 3.095 N/A ARG 156.A N ILE 130.A O no hydrogen 3.198 N/A ARG 156.A NH1 GLY 153.A O no hydrogen 3.328 N/A ARG 156.A NH1 MET 155.A O no hydrogen 2.550 N/A LEU 158.A N ARG 128.A O no hydrogen 2.799 N/A ASP 163.A N ASP 162.A OD1 no hydrogen 2.724 N/A HIS 164.A ND1 ASP 163.A OD1 no hydrogen 2.886 N/A MET 167.A N ARG 186.A O no hydrogen 3.136 N/A ARG 171.A N GLN 168.A O no hydrogen 3.096 N/A LYS 172.A NZ GLU 169.A O no hydrogen 3.489 N/A LYS 172.A NZ HIS 170.A O no hydrogen 3.513 N/A TRP 177.A NE1 GLU 203.A OE1 no hydrogen 2.747 N/A CYS 178.A N PHE 175.A O no hydrogen 3.018 N/A CYS 178.A SG PRO 174.A O no hydrogen 3.986 N/A GLU 181.A N GLU 181.A OE1 no hydrogen 2.807 N/A SER 182.A OG THR 187.A O no hydrogen 3.220 N/A LEU 183.A N ALA 179.A O no hydrogen 3.041 N/A LYS 184.A N PRO 180.A O no hydrogen 3.096 N/A LYS 184.A NZ ASP 225.A OD1 no hydrogen 3.083 N/A LYS 184.A NZ ASP 225.A OD2 no hydrogen 3.124 N/A THR 185.A N GLU 181.A O no hydrogen 3.115 N/A THR 185.A OG1 GLU 181.A O no hydrogen 2.985 N/A THR 185.A OG1 THR 187.A OG1 no hydrogen 2.952 N/A ARG 186.A N SER 182.A O no hydrogen 3.078 N/A ARG 186.A NH2 GLN 168.A O no hydrogen 3.014 N/A ARG 186.A NH2 ARG 171.A O no hydrogen 3.239 N/A THR 187.A OG1 THR 185.A O no hydrogen 3.078 N/A THR 187.A OG1 THR 185.A OG1 no hydrogen 2.952 N/A PHE 188.A N TYR 165.A O no hydrogen 2.919 N/A SER 189.A N SER 192.A OG no hydrogen 3.234 N/A HIS 190.A NE2 PHE 129.A O no hydrogen 3.184 N/A SER 192.A N SER 189.A OG no hydrogen 3.064 N/A SER 192.A OG SER 189.A O no hydrogen 3.251 N/A ASP 193.A N SER 189.A O no hydrogen 3.060 N/A THR 194.A N HIS 190.A O no hydrogen 3.245 N/A THR 194.A OG1 HIS 190.A O no hydrogen 3.257 N/A THR 194.A OG1 PRO 257.A O no hydrogen 3.350 N/A TRP 195.A N ALA 191.A O no hydrogen 3.048 N/A MET 196.A N SER 192.A O no hydrogen 3.355 N/A PHE 197.A N ASP 193.A O no hydrogen 2.992 N/A PHE 197.A N THR 194.A O no hydrogen 3.066 N/A GLY 198.A N TRP 195.A O no hydrogen 3.340 N/A THR 200.A N MET 196.A O no hydrogen 3.196 N/A THR 200.A OG1 MET 196.A O no hydrogen 2.743 N/A LEU 201.A N PHE 197.A O no hydrogen 2.991 N/A TRP 202.A N GLY 198.A O no hydrogen 2.880 N/A TRP 202.A NE1 PRO 232.A O no hydrogen 2.804 N/A GLU 203.A N VAL 199.A O no hydrogen 2.948 N/A MET 204.A N THR 200.A O no hydrogen 2.949 N/A MET 204.A N LEU 201.A O no hydrogen 2.765 N/A PHE 205.A N LEU 201.A O no hydrogen 2.733 N/A THR 206.A N TRP 202.A O no hydrogen 2.873 N/A THR 206.A OG1 TRP 202.A O no hydrogen 2.822 N/A THR 206.A OG1 GLU 203.A O no hydrogen 3.528 N/A TYR 207.A N MET 204.A O no hydrogen 3.158 N/A GLY 208.A N GLU 203.A O no hydrogen 2.841 N/A GLN 209.A N THR 206.A O no hydrogen 3.298 N/A GLN 209.A N THR 206.A OG1 no hydrogen 3.016 N/A LEU 215.A N TRP 212.A O no hydrogen 3.013 N/A ASN 216.A N GLN 219.A OE1 no hydrogen 2.935 N/A GLN 219.A N ASN 216.A OD1 no hydrogen 2.905 N/A ILE 220.A N ASN 216.A O no hydrogen 2.960 N/A LEU 221.A N GLY 217.A O no hydrogen 3.123 N/A HIS 222.A N SER 218.A O no hydrogen 3.128 N/A LYS 223.A N GLN 219.A O no hydrogen 3.072 N/A LYS 223.A NZ GLU 229.A OE1 no hydrogen 3.048 N/A LYS 223.A NZ GLU 229.A OE2 no hydrogen 3.490 N/A ILE 224.A N ILE 220.A O no hydrogen 3.084 N/A ASP 225.A N LEU 221.A O no hydrogen 3.069 N/A LYS 226.A N HIS 222.A O no hydrogen 2.856 N/A LYS 226.A NZ ASP 225.A OD2 no hydrogen 2.995 N/A GLU 229.A N LYS 223.A O no hydrogen 3.069 N/A ARG 230.A NE TRP 249.A O no hydrogen 3.229 N/A ARG 230.A NH1 ILE 224.A O no hydrogen 2.777 N/A ARG 230.A NH1 GLU 229.A O no hydrogen 2.840 N/A ARG 230.A NH2 ILE 224.A O no hydrogen 3.427 N/A ARG 230.A NH2 TRP 249.A O no hydrogen 3.397 N/A ARG 233.A NH1 GLU 235.A O no hydrogen 3.524 N/A ARG 233.A NH1 CYS 237.A O no hydrogen 2.878 N/A CYS 237.A N PRO 234.A O no hydrogen 3.174 N/A CYS 237.A SG PRO 238.A O no hydrogen 3.180 N/A TYR 242.A N PRO 238.A O no hydrogen 3.198 N/A TYR 242.A OH LEU 231.A O no hydrogen 2.575 N/A ASN 243.A N GLN 239.A O no hydrogen 2.907 N/A VAL 244.A N ASP 240.A O no hydrogen 3.248 N/A VAL 244.A N ILE 241.A O no hydrogen 2.826 N/A MET 245.A N ILE 241.A O no hydrogen 2.963 N/A VAL 246.A N TYR 242.A O no hydrogen 3.229 N/A GLN 247.A N ASN 243.A O no hydrogen 3.219 N/A GLN 247.A NE2 ASN 243.A O no hydrogen 3.367 N/A CYS 248.A N VAL 244.A O no hydrogen 3.138 N/A CYS 248.A SG THR 194.A O no hydrogen 3.719 N/A CYS 248.A SG VAL 244.A O no hydrogen 3.605 N/A TRP 249.A N VAL 246.A O no hydrogen 2.678 N/A ALA 250.A N GLN 247.A O no hydrogen 2.980 N/A HIS 251.A NE2 ASP 225.A OD1 no hydrogen 2.750 N/A GLU 254.A N GLU 254.A OE1 no hydrogen 2.830 N/A ASP 255.A N LYS 252.A O no hydrogen 2.999 N/A ARG 256.A N PRO 253.A O no hydrogen 3.086 N/A ARG 256.A NE ALA 250.A O no hydrogen 2.877 N/A ARG 256.A NH1 GLU 181.A OE2 no hydrogen 3.023 N/A ARG 256.A NH2 GLU 181.A OE1 no hydrogen 2.984 N/A ARG 256.A NH2 ALA 250.A O no hydrogen 3.273 N/A ALA 261.A N THR 258.A OG1 no hydrogen 3.194 N/A LEU 262.A N THR 258.A O no hydrogen 2.895 N/A ARG 263.A N PHE 259.A O no hydrogen 3.018 N/A ASP 264.A N VAL 260.A O no hydrogen 3.344 N/A PHE 265.A N ALA 261.A O no hydrogen 3.050 N/A LEU 266.A N LEU 262.A O no hydrogen 2.866 N/A LEU 267.A N ASP 264.A O no hydrogen 2.661 N/A GLU 268.A N ASP 264.A O no hydrogen 2.535 N/A ALA 269.A N PHE 265.A O no hydrogen 3.327 N/A