Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8hv3_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ALA 3.A N GLU 2.A OE2 no hydrogen 3.287 N/A ASN 5.A ND2 TYR 66.A OH no hydrogen 3.211 N/A ASN 5.A ND2 SER 70.A OG no hydrogen 3.284 N/A ALA 7.A N ASN 5.A OD1 no hydrogen 3.204 N/A ARG 10.A NH1 TYR 303.A OH no hydrogen 2.902 N/A LEU 12.A N ILE 82.A O no hydrogen 2.799 N/A LYS 13.A N GLU 16.A OE1 no hydrogen 2.937 N/A LYS 13.A NZ GLU 36.A OE2 no hydrogen 2.730 N/A GLU 16.A N LYS 13.A O no hydrogen 3.057 N/A LYS 18.A N LEU 32.A O no hydrogen 2.960 N/A ILE 20.A N LYS 30.A O no hydrogen 2.854 N/A LYS 21.A N LYS 30.A O no hydrogen 3.237 N/A LEU 23.A N VAL 28.A O no hydrogen 2.763 N/A THR 27.A N GLU 48.A O no hydrogen 3.044 N/A VAL 28.A N GLY 24.A O no hydrogen 3.116 N/A TYR 29.A N ILE 46.A O no hydrogen 2.800 N/A TYR 29.A OH GLU 48.A OE2 no hydrogen 3.349 N/A LYS 30.A N LYS 21.A O no hydrogen 2.766 N/A GLY 31.A N VAL 44.A O no hydrogen 2.974 N/A LEU 32.A N LYS 18.A O no hydrogen 2.969 N/A TRP 33.A N ILE 42.A O no hydrogen 2.870 N/A TRP 33.A NE1 GLU 16.A OE2 no hydrogen 3.145 N/A ILE 34.A N GLU 16.A O no hydrogen 2.781 N/A GLU 36.A N GLU 16.A OE2 no hydrogen 3.258 N/A GLU 38.A N PRO 35.A O no hydrogen 3.238 N/A LYS 41.A N ASP 296.A O no hydrogen 2.941 N/A LYS 41.A NZ ASP 293.A O no hydrogen 3.090 N/A ILE 42.A N TRP 33.A O no hydrogen 2.947 N/A VAL 44.A N GLY 31.A O no hydrogen 3.029 N/A ALA 45.A N MET 92.A O no hydrogen 2.880 N/A ILE 46.A N TYR 29.A O no hydrogen 2.912 N/A LYS 47.A N LEU 90.A O no hydrogen 2.877 N/A LYS 47.A NZ GLU 64.A OE1 no hydrogen 3.411 N/A LYS 47.A NZ GLU 64.A OE2 no hydrogen 3.166 N/A GLU 48.A N THR 27.A O no hydrogen 3.089 N/A LEU 49.A N VAL 88.A O no hydrogen 3.175 N/A ALA 57.A N SER 54.A OG no hydrogen 3.287 N/A ASN 58.A N SER 54.A O no hydrogen 3.218 N/A LYS 59.A N PRO 55.A O no hydrogen 3.221 N/A GLU 60.A N LYS 56.A O no hydrogen 3.127 N/A ILE 61.A N ALA 57.A O no hydrogen 3.092 N/A LEU 62.A N ASN 58.A O no hydrogen 3.212 N/A ASP 63.A N LYS 59.A O no hydrogen 3.049 N/A GLU 64.A N GLU 60.A O no hydrogen 3.118 N/A ALA 65.A N ILE 61.A O no hydrogen 3.042 N/A TYR 66.A N LEU 62.A O no hydrogen 2.763 N/A VAL 67.A N ASP 63.A O no hydrogen 3.048 N/A MET 68.A N GLU 64.A O no hydrogen 2.837 N/A ALA 69.A N ALA 65.A O no hydrogen 2.885 N/A SER 70.A N VAL 67.A O no hydrogen 2.949 N/A SER 70.A OG TYR 66.A O no hydrogen 2.424 N/A ASP 72.A N TYR 129.A OH no hydrogen 2.906 N/A HIS 75.A N ASN 73.A OD1 no hydrogen 2.917 N/A HIS 75.A ND1 VAL 153.A O no hydrogen 3.206 N/A VAL 76.A N ASN 73.A O no hydrogen 3.478 N/A CYS 77.A N ILE 155.A O no hydrogen 3.088 N/A CYS 77.A SG THR 156.A OG1 no hydrogen 3.713 N/A ARG 78.A NH2 ALA 300.A O no hydrogen 3.368 N/A LEU 80.A N ILE 91.A O no hydrogen 2.880 N/A GLY 81.A N ILE 91.A O no hydrogen 3.344 N/A ILE 82.A N ARG 10.A O no hydrogen 2.944 N/A CYS 83.A N GLN 89.A O no hydrogen 2.897 N/A CYS 83.A SG LEU 12.A O no hydrogen 2.827 N/A THR 85.A OG1 THR 87.A O no hydrogen 2.531 N/A THR 85.A OG1 GLN 89.A OE1 no hydrogen 3.348 N/A THR 87.A OG1 GLU 48.A OE1 no hydrogen 2.792 N/A GLN 89.A N CYS 83.A O no hydrogen 3.000 N/A LEU 90.A N LYS 47.A O no hydrogen 2.784 N/A ILE 91.A N GLY 81.A O no hydrogen 2.939 N/A MET 92.A N ALA 45.A O no hydrogen 2.830 N/A GLN 93.A N ARG 78.A O no hydrogen 3.180 N/A GLN 93.A NE2 ASP 299.A OD1 no hydrogen 3.424 N/A GLN 93.A NE2 ASP 301.A OD2 no hydrogen 2.980 N/A LEU 94.A N PRO 43.A O no hydrogen 3.116 N/A PHE 97.A N VAL 147.A O no hydrogen 3.141 N/A GLY 98.A N MET 95.A O no hydrogen 3.127 N/A CYS 99.A SG ASP 102.A OD2 no hydrogen 3.348 N/A LEU 100.A N VAL 145.A O no hydrogen 2.867 N/A LEU 101.A N ALA 142.A O no hydrogen 3.340 N/A TYR 103.A N CYS 99.A O no hydrogen 3.054 N/A VAL 104.A N LEU 100.A O no hydrogen 2.807 N/A ARG 105.A N LEU 101.A O no hydrogen 3.086 N/A ARG 105.A NE GLY 213.A O no hydrogen 2.916 N/A ARG 105.A NH2 GLY 213.A O no hydrogen 3.168 N/A GLU 106.A N ASP 102.A O no hydrogen 2.882 N/A HIS 107.A ND1 TYR 103.A O no hydrogen 3.080 N/A LYS 108.A NZ PHE 212.A O no hydrogen 3.489 N/A ASN 110.A N HIS 107.A O no hydrogen 2.738 N/A ILE 111.A N LYS 108.A O no hydrogen 3.406 N/A SER 113.A N ASP 286.A OD1 no hydrogen 3.155 N/A SER 113.A N ASP 286.A OD2 no hydrogen 3.454 N/A SER 113.A OG ASP 286.A OD1 no hydrogen 3.502 N/A SER 113.A OG ASP 286.A OD2 no hydrogen 2.540 N/A GLN 114.A NE2 ALA 274.A O no hydrogen 3.087 N/A LEU 116.A N GLY 112.A O no hydrogen 3.281 N/A LEU 117.A N SER 113.A O no hydrogen 3.019 N/A ASN 118.A N GLN 114.A O no hydrogen 2.938 N/A TRP 119.A N TYR 115.A O no hydrogen 2.857 N/A TRP 119.A NE1 PRO 150.A O no hydrogen 2.841 N/A CYS 120.A N LEU 116.A O no hydrogen 3.087 N/A CYS 120.A SG LEU 116.A O no hydrogen 3.430 N/A VAL 121.A N LEU 117.A O no hydrogen 3.004 N/A GLN 122.A N ASN 118.A O no hydrogen 2.890 N/A GLN 122.A NE2 GLN 151.A O no hydrogen 2.895 N/A ILE 123.A N TRP 119.A O no hydrogen 2.994 N/A ALA 124.A N CYS 120.A O no hydrogen 3.109 N/A LYS 125.A N VAL 121.A O no hydrogen 2.761 N/A GLY 126.A N GLN 122.A O no hydrogen 2.916 N/A MET 127.A N ILE 123.A O no hydrogen 2.916 N/A ASN 128.A N ALA 124.A O no hydrogen 2.891 N/A TYR 129.A N LYS 125.A O no hydrogen 2.959 N/A LEU 130.A N GLY 126.A O no hydrogen 3.013 N/A GLU 131.A N MET 127.A O no hydrogen 3.021 N/A ASP 132.A N ASN 128.A O no hydrogen 2.948 N/A ARG 133.A N TYR 129.A O no hydrogen 3.024 N/A ARG 133.A NH2 SER 70.A O no hydrogen 2.344 N/A ARG 133.A NH2 TYR 129.A OH no hydrogen 3.287 N/A ARG 134.A N GLU 131.A O no hydrogen 2.702 N/A ARG 134.A NH1 GLY 165.A O no hydrogen 2.927 N/A ARG 134.A NH2 GLY 165.A O no hydrogen 3.363 N/A LEU 135.A N LEU 130.A O no hydrogen 2.878 N/A VAL 136.A N LYS 162.A O no hydrogen 2.981 N/A HIS 137.A N ASP 198.A OD2 no hydrogen 2.918 N/A HIS 137.A NE2 THR 156.A O no hydrogen 2.812 N/A ARG 138.A N ASP 198.A OD1 no hydrogen 3.154 N/A ARG 138.A NH1 ARG 160.A O no hydrogen 2.749 N/A ASP 139.A N HIS 137.A ND1 no hydrogen 2.889 N/A ALA 142.A N GLU 208.A OE2 no hydrogen 3.022 N/A ARG 143.A NH2 ASP 139.A OD1 no hydrogen 3.272 N/A ASN 144.A N ALA 141.A O no hydrogen 2.830 N/A ASN 144.A ND2 ASP 139.A O no hydrogen 2.575 N/A VAL 145.A N ALA 142.A O no hydrogen 3.359 N/A LEU 146.A N LYS 154.A O no hydrogen 2.773 N/A VAL 147.A N GLY 98.A O no hydrogen 2.918 N/A LYS 148.A N HIS 152.A O no hydrogen 2.914 N/A LYS 148.A NZ ASP 299.A OD2 no hydrogen 3.291 N/A LYS 148.A NZ ASP 301.A OD2 no hydrogen 2.656 N/A THR 149.A N HIS 152.A O no hydrogen 3.200 N/A THR 149.A OG1 GLN 151.A OE1 no hydrogen 3.126 N/A GLN 151.A N THR 149.A OG1 no hydrogen 3.117 N/A GLN 151.A NE2 TYR 115.A OH no hydrogen 2.905 N/A HIS 152.A N THR 149.A O no hydrogen 2.896 N/A HIS 152.A NE2 PRO 74.A O no hydrogen 2.799 N/A VAL 153.A N GLN 122.A OE1 no hydrogen 2.923 N/A LYS 154.A N LEU 146.A O no hydrogen 2.912 N/A LYS 154.A NZ GLN 93.A OE1 no hydrogen 2.640 N/A LYS 154.A NZ ASP 301.A OD1 no hydrogen 2.699 N/A LYS 154.A NZ ASP 301.A OD2 no hydrogen 3.327 N/A ILE 155.A N HIS 75.A O no hydrogen 2.815 N/A THR 156.A N ASN 144.A O no hydrogen 2.831 N/A ASP 157.A N THR 156.A OG1 no hydrogen 2.792 N/A ARG 160.A NE ARG 138.A O no hydrogen 3.103 N/A ARG 160.A NH2 ARG 138.A O no hydrogen 3.229 N/A ARG 160.A NH2 TYR 193.A OH no hydrogen 3.009 N/A ALA 161.A N PHE 158.A O no hydrogen 2.822 N/A LYS 162.A N VAL 136.A O no hydrogen 2.918 N/A ALA 168.A N GLY 165.A O no hydrogen 3.124 N/A TYR 171.A N TYR 193.A O no hydrogen 3.238 N/A LYS 181.A NZ TYR 217.A O no hydrogen 3.028 N/A LYS 181.A NZ ILE 220.A O no hydrogen 2.829 N/A TRP 182.A N PRO 179.A O no hydrogen 3.093 N/A TRP 182.A NE1 GLU 208.A OE2 no hydrogen 2.741 N/A MET 183.A N ILE 180.A O no hydrogen 3.018 N/A GLU 186.A N GLU 186.A OE2 no hydrogen 2.834 N/A SER 187.A N ALA 184.A O no hydrogen 3.185 N/A SER 187.A OG ILE 192.A O no hydrogen 2.500 N/A ILE 188.A N ALA 184.A O no hydrogen 3.312 N/A LEU 189.A N LEU 185.A O no hydrogen 2.998 N/A HIS 190.A N GLU 186.A O no hydrogen 3.126 N/A ILE 192.A N GLU 186.A O no hydrogen 3.231 N/A THR 194.A N SER 197.A OG no hydrogen 2.846 N/A GLN 196.A NE2 ALA 257.A O no hydrogen 3.240 N/A GLN 196.A NE2 PRO 261.A O no hydrogen 3.060 N/A SER 197.A N THR 194.A OG1 no hydrogen 3.180 N/A SER 197.A OG THR 194.A O no hydrogen 2.718 N/A ASP 198.A N THR 194.A O no hydrogen 3.147 N/A VAL 199.A N HIS 195.A O no hydrogen 2.921 N/A TRP 200.A N GLN 196.A O no hydrogen 3.384 N/A SER 201.A N SER 197.A O no hydrogen 3.347 N/A SER 201.A OG TRP 182.A O no hydrogen 2.657 N/A SER 201.A OG SER 197.A O no hydrogen 3.342 N/A TYR 202.A N ASP 198.A O no hydrogen 2.888 N/A TYR 202.A OH CYS 120.A O no hydrogen 2.476 N/A GLY 203.A N VAL 199.A O no hydrogen 3.062 N/A VAL 204.A N TRP 200.A O no hydrogen 3.154 N/A THR 205.A N SER 201.A O no hydrogen 2.834 N/A THR 205.A OG1 SER 201.A O no hydrogen 2.748 N/A VAL 206.A N TYR 202.A O no hydrogen 2.736 N/A TRP 207.A N GLY 203.A O no hydrogen 3.079 N/A TRP 207.A NE1 PRO 236.A O no hydrogen 2.788 N/A GLU 208.A N VAL 204.A O no hydrogen 2.892 N/A LEU 209.A N THR 205.A O no hydrogen 3.069 N/A MET 210.A N VAL 206.A O no hydrogen 2.945 N/A THR 211.A N TRP 207.A O no hydrogen 3.051 N/A THR 211.A OG1 TRP 207.A O no hydrogen 3.009 N/A THR 211.A OG1 GLU 208.A O no hydrogen 3.149 N/A PHE 212.A N LEU 209.A O no hydrogen 3.017 N/A GLY 213.A N GLU 208.A O no hydrogen 2.779 N/A SER 214.A N THR 211.A OG1 no hydrogen 3.126 N/A SER 214.A OG THR 211.A O no hydrogen 2.806 N/A ILE 220.A N TYR 217.A O no hydrogen 2.959 N/A GLU 224.A N PRO 221.A O no hydrogen 2.959 N/A ILE 225.A N ALA 222.A O no hydrogen 3.365 N/A SER 227.A N GLU 224.A O no hydrogen 2.867 N/A ILE 228.A N GLU 224.A O no hydrogen 3.031 N/A LEU 229.A N ILE 225.A O no hydrogen 2.919 N/A GLU 230.A N SER 226.A O no hydrogen 3.080 N/A LYS 231.A N SER 227.A O no hydrogen 2.832 N/A GLY 232.A N LEU 229.A O no hydrogen 3.114 N/A GLU 233.A N ILE 228.A O no hydrogen 3.135 N/A ARG 234.A NE TRP 253.A O no hydrogen 2.781 N/A ARG 234.A NH1 TRP 253.A O no hydrogen 2.889 N/A ARG 234.A NH2 LEU 229.A O no hydrogen 3.004 N/A ARG 234.A NH2 GLU 233.A O no hydrogen 2.855 N/A GLN 237.A NE2 CYS 241.A O no hydrogen 2.935 N/A CYS 241.A N PRO 238.A O no hydrogen 2.881 N/A THR 242.A N TYR 280.A O no hydrogen 3.259 N/A THR 242.A OG1 TYR 280.A O no hydrogen 2.539 N/A TYR 246.A N THR 242.A O no hydrogen 3.084 N/A TYR 246.A OH LEU 235.A O no hydrogen 2.539 N/A MET 247.A N ILE 243.A O no hydrogen 2.803 N/A ILE 248.A N VAL 245.A O no hydrogen 3.173 N/A MET 249.A N VAL 245.A O no hydrogen 3.260 N/A VAL 250.A N TYR 246.A O no hydrogen 2.912 N/A LYS 251.A N MET 247.A O no hydrogen 3.013 N/A CYS 252.A N ILE 248.A O no hydrogen 3.361 N/A CYS 252.A N MET 249.A O no hydrogen 2.960 N/A CYS 252.A SG ILE 248.A O no hydrogen 3.454 N/A TRP 253.A N VAL 250.A O no hydrogen 2.903 N/A MET 254.A N LYS 251.A O no hydrogen 3.480 N/A SER 259.A N ASP 256.A O no hydrogen 2.929 N/A SER 259.A OG ASP 256.A OD2 no hydrogen 2.834 N/A ARG 260.A N ALA 257.A O no hydrogen 3.178 N/A ARG 260.A NE MET 254.A O no hydrogen 2.785 N/A ARG 260.A NH1 GLU 186.A OE1 no hydrogen 3.560 N/A ARG 260.A NH1 GLU 186.A OE2 no hydrogen 2.794 N/A ARG 260.A NH1 MET 254.A O no hydrogen 2.944 N/A ARG 260.A NH2 GLU 186.A OE1 no hydrogen 2.916 N/A ARG 260.A NH2 GLN 196.A O no hydrogen 2.927 N/A LYS 262.A N GLU 265.A OE1 no hydrogen 2.907 N/A LYS 262.A NZ GLU 131.A OE1 no hydrogen 2.789 N/A LYS 262.A NZ GLN 196.A OE1 no hydrogen 2.675 N/A GLU 265.A N LYS 262.A O no hydrogen 2.730 N/A LEU 266.A N LYS 262.A O no hydrogen 3.017 N/A ILE 267.A N PHE 263.A O no hydrogen 2.988 N/A ILE 268.A N ARG 264.A O no hydrogen 3.378 N/A GLU 269.A N GLU 265.A O no hydrogen 2.711 N/A PHE 270.A N LEU 266.A O no hydrogen 2.911 N/A SER 271.A N ILE 267.A O no hydrogen 2.952 N/A SER 271.A OG ILE 267.A O no hydrogen 2.783 N/A LYS 272.A N ILE 268.A O no hydrogen 2.945 N/A LYS 272.A NZ GLU 269.A OE1 no hydrogen 3.083 N/A MET 273.A N GLU 269.A O no hydrogen 3.152 N/A ALA 274.A N PHE 270.A O no hydrogen 2.773 N/A ARG 275.A N SER 271.A O no hydrogen 3.121 N/A ARG 275.A N LYS 272.A O no hydrogen 3.373 N/A ASP 276.A N MET 273.A O no hydrogen 2.961 N/A ARG 279.A N ASP 276.A O no hydrogen 3.043 N/A TYR 280.A N PRO 277.A O no hydrogen 3.032 N/A LEU 281.A N PRO 277.A O no hydrogen 2.934 N/A VAL 282.A N ILE 240.A O no hydrogen 2.982 N/A ARG 288.A N GLY 285.A O no hydrogen 3.367 N/A MET 289.A N ASP 286.A O no hydrogen 3.426 N/A VAL 298.A N LYS 41.A O no hydrogen 2.994 N/A ASP 301.A N ASP 299.A OD2 no hydrogen 2.792 N/A GLU 302.A N ASP 299.A O no hydrogen 2.985 N/A TYR 303.A N ALA 300.A O no hydrogen 2.808 N/A TYR 303.A OH GLU 38.A OE2 no hydrogen 2.350 N/A GLN 307.A NE2 ASP 72.A OD2 no hydrogen 3.531 N/A