Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8ip8_bl.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): THR 7.A N HIS 5.A ND1 no hydrogen 3.080 N/A ASP 8.A N HIS 5.A O no hydrogen 3.150 N/A GLU 12.A N ASP 8.A O no hydrogen 2.655 N/A MET 13.A N LYS 9.A O no hydrogen 2.857 N/A MET 13.A N ASN 10.A O no hydrogen 3.070 N/A TRP 14.A N ASN 10.A O no hydrogen 2.883 N/A LYS 15.A N ILE 11.A O no hydrogen 3.014 N/A LYS 18.A N TRP 14.A O no hydrogen 2.826 N/A LEU 19.A N LYS 15.A O no hydrogen 3.021 N/A ILE 20.A N ILE 16.A O no hydrogen 2.879 N/A LYS 21.A N LYS 17.A O no hydrogen 2.830 N/A GLY 22.A N LYS 18.A O no hydrogen 2.677 N/A LEU 23.A N LEU 19.A O no hydrogen 3.313 N/A GLY 28.A N ASN 128.A O no hydrogen 2.664 N/A SER 32.A N ASN 29.A O no hydrogen 3.017 N/A SER 32.A OG ASN 29.A O no hydrogen 2.381 N/A MET 33.A N ASP 127.A O no hydrogen 3.029 N/A ILE 34.A N THR 96.A O no hydrogen 2.835 N/A SER 35.A N LEU 125.A O no hydrogen 3.052 N/A LEU 36.A N LEU 94.A O no hydrogen 2.949 N/A ILE 37.A N LEU 123.A O no hydrogen 2.710 N/A MET 38.A N LEU 92.A O no hydrogen 2.647 N/A ASP 42.A N PRO 39.A O no hydrogen 3.327 N/A VAL 47.A N GLN 43.A O no hydrogen 3.357 N/A THR 48.A N VAL 44.A O no hydrogen 3.081 N/A THR 48.A OG1 VAL 44.A O no hydrogen 2.894 N/A THR 48.A OG1 SER 45.A O no hydrogen 2.839 N/A LYS 49.A N SER 45.A O no hydrogen 3.332 N/A MET 50.A N ARG 46.A O no hydrogen 2.999 N/A LEU 51.A N VAL 47.A O no hydrogen 2.920 N/A GLY 52.A N THR 48.A O no hydrogen 3.098 N/A ASP 53.A N LYS 49.A O no hydrogen 3.158 N/A GLU 54.A N MET 50.A O no hydrogen 3.164 N/A TYR 55.A N LEU 51.A O no hydrogen 2.956 N/A GLY 56.A N GLY 52.A O no hydrogen 3.206 N/A THR 57.A N ASP 53.A O no hydrogen 2.725 N/A THR 57.A OG1 ASP 53.A O no hydrogen 3.045 N/A ALA 58.A N GLU 54.A O no hydrogen 2.654 N/A SER 59.A N TYR 55.A O no hydrogen 3.043 N/A SER 59.A OG TYR 55.A O no hydrogen 2.994 N/A ASN 60.A ND2 THR 57.A O no hydrogen 3.397 N/A ILE 61.A N ALA 58.A O no hydrogen 3.302 N/A ASN 66.A ND2 THR 31.A OG1 no hydrogen 3.007 N/A SER 69.A OG VAL 65.A O no hydrogen 2.759 N/A VAL 70.A N ASN 66.A O no hydrogen 2.755 N/A LEU 71.A N ARG 67.A O no hydrogen 3.113 N/A GLY 72.A N GLN 68.A O no hydrogen 3.111 N/A ALA 73.A N SER 69.A O no hydrogen 2.716 N/A ILE 74.A N VAL 70.A O no hydrogen 2.709 N/A THR 75.A N LEU 71.A O no hydrogen 3.006 N/A THR 75.A OG1 LEU 71.A O no hydrogen 2.674 N/A SER 76.A N GLY 72.A O no hydrogen 3.196 N/A SER 76.A OG GLY 72.A O no hydrogen 3.292 N/A ALA 77.A N ALA 73.A O no hydrogen 3.265 N/A GLN 78.A N ILE 74.A O no hydrogen 3.001 N/A GLN 79.A N THR 75.A O no hydrogen 2.922 N/A GLN 79.A N SER 76.A O no hydrogen 3.074 N/A ARG 80.A N SER 76.A O no hydrogen 2.816 N/A ARG 80.A NH1 ASP 112.A OD1 no hydrogen 2.476 N/A LEU 81.A N ALA 77.A O no hydrogen 2.948 N/A LYS 82.A N GLN 79.A O no hydrogen 3.319 N/A LEU 83.A N ARG 80.A O no hydrogen 3.227 N/A TYR 84.A N LEU 81.A O no hydrogen 2.928 N/A TYR 84.A OH ASP 112.A OD2 no hydrogen 2.503 N/A ARG 86.A N ASN 85.A OD1 no hydrogen 2.650 N/A ASN 90.A N PRO 88.A O no hydrogen 2.565 N/A GLY 91.A N PRO 88.A O no hydrogen 3.141 N/A LEU 92.A N MET 38.A O no hydrogen 2.594 N/A VAL 93.A N PHE 113.A O no hydrogen 3.247 N/A LEU 94.A N LEU 36.A O no hydrogen 2.988 N/A TYR 95.A N ILE 111.A O no hydrogen 2.714 N/A TYR 95.A OH THR 132.A OG1 no hydrogen 2.216 N/A THR 96.A N ILE 34.A O no hydrogen 3.171 N/A THR 96.A OG1 TYR 95.A O no hydrogen 2.694 N/A THR 96.A OG1 THR 110.A OG1 no hydrogen 3.268 N/A GLY 97.A N VAL 109.A O no hydrogen 3.072 N/A ILE 99.A N LYS 107.A O no hydrogen 3.464 N/A VAL 100.A N ARG 27.A O no hydrogen 2.978 N/A THR 101.A OG1 VAL 100.A O no hydrogen 2.443 N/A THR 101.A OG1 LYS 105.A O no hydrogen 2.745 N/A LYS 105.A N VAL 100.A O no hydrogen 3.142 N/A LYS 105.A N THR 101.A OG1 no hydrogen 3.225 N/A VAL 109.A N GLY 97.A O no hydrogen 2.962 N/A THR 110.A OG1 TYR 95.A O no hydrogen 3.097 N/A THR 110.A OG1 THR 96.A OG1 no hydrogen 3.268 N/A ILE 111.A N TYR 95.A O no hydrogen 3.001 N/A PHE 113.A N VAL 93.A O no hydrogen 3.079 N/A LYS 117.A NZ LEU 138.A O no hydrogen 3.534 N/A LYS 117.A NZ SER 141.A O no hydrogen 2.285 N/A LEU 123.A N ILE 37.A O no hydrogen 3.088 N/A TYR 124.A OH GLU 54.A OE1 no hydrogen 3.048 N/A LEU 125.A N SER 35.A O no hydrogen 3.015 N/A CYS 126.A SG TYR 124.A OH no hydrogen 2.943 N/A ASP 127.A N MET 33.A O no hydrogen 2.865 N/A HIS 131.A N SER 35.A OG no hydrogen 3.186 N/A HIS 131.A NE2 ASP 127.A OD2 no hydrogen 2.529 N/A THR 132.A OG1 TYR 95.A OH no hydrogen 2.216 N/A SER 136.A OG THR 132.A O no hydrogen 2.700 N/A GLU 137.A N GLU 133.A O no hydrogen 2.934 N/A LEU 138.A N LEU 135.A O no hydrogen 3.241 N/A LEU 139.A N LEU 135.A O no hydrogen 3.288 N/A SER 141.A N GLU 137.A O no hydrogen 3.106 N/A SER 141.A OG GLU 137.A O no hydrogen 2.622 N/A SER 141.A OG GLU 137.A OE1 no hydrogen 3.530 N/A SER 141.A OG GLU 140.A OE2 no hydrogen 3.477 N/A PHE 145.A N LEU 160.A O no hydrogen 2.919 N/A GLY 146.A N GLY 224.A O no hydrogen 3.029 N/A PHE 147.A N GLY 158.A O no hydrogen 2.729 N/A ILE 148.A N ILE 226.A O no hydrogen 2.910 N/A ILE 149.A N LEU 156.A O no hydrogen 2.895 N/A MET 150.A N ALA 228.A O no hydrogen 2.833 N/A ASP 151.A N GLY 154.A O no hydrogen 3.372 N/A ASN 153.A N ASP 151.A OD1 no hydrogen 2.543 N/A THR 155.A N PHE 171.A O no hydrogen 3.186 N/A THR 155.A OG1 ILE 149.A O no hydrogen 2.629 N/A LEU 156.A N ILE 149.A O no hydrogen 2.891 N/A PHE 157.A N HIS 169.A O no hydrogen 2.725 N/A GLY 158.A N PHE 147.A O no hydrogen 2.843 N/A THR 159.A N GLU 166.A O no hydrogen 2.991 N/A THR 159.A OG1 PHE 145.A O no hydrogen 2.910 N/A LEU 160.A N PHE 145.A O no hydrogen 2.859 N/A SER 161.A N ASN 163.A O no hydrogen 3.136 N/A SER 161.A OG ASN 163.A O no hydrogen 3.354 N/A GLY 162.A N SER 161.A OG no hydrogen 2.489 N/A ARG 165.A NH1 ASN 266.A OD1 no hydrogen 2.549 N/A ARG 165.A NH2 ASN 163.A OD1 no hydrogen 3.249 N/A GLU 166.A N THR 159.A O no hydrogen 3.078 N/A LEU 168.A N PHE 157.A O no hydrogen 2.788 N/A HIS 169.A N PHE 157.A O no hydrogen 3.166 N/A PHE 171.A N THR 155.A O no hydrogen 3.245 N/A ARG 181.A N HIS 179.A ND1 no hydrogen 3.017 N/A SER 185.A N GLY 182.A O no hydrogen 3.090 N/A SER 185.A OG GLY 182.A O no hydrogen 2.674 N/A ALA 186.A N GLY 183.A O no hydrogen 3.235 N/A PHE 189.A N SER 185.A O no hydrogen 2.731 N/A ALA 190.A N ALA 186.A O no hydrogen 2.745 N/A ARG 191.A N LEU 187.A O no hydrogen 2.960 N/A LEU 192.A N ARG 188.A O no hydrogen 2.830 N/A ARG 193.A N PHE 189.A O no hydrogen 2.846 N/A MET 194.A N ALA 190.A O no hydrogen 3.171 N/A GLU 195.A N ARG 191.A O no hydrogen 3.367 N/A ARG 197.A N ARG 193.A O no hydrogen 3.131 N/A HIS 198.A N MET 194.A O no hydrogen 2.859 N/A ASN 199.A N GLU 195.A O no hydrogen 2.803 N/A TYR 200.A N LYS 196.A O no hydrogen 3.127 N/A TYR 200.A OH ASP 151.A O no hydrogen 2.503 N/A VAL 201.A N ARG 197.A O no hydrogen 3.117 N/A ARG 202.A N HIS 198.A O no hydrogen 2.954 N/A LYS 203.A N ASN 199.A O no hydrogen 2.820 N/A THR 204.A N TYR 200.A O no hydrogen 3.085 N/A THR 204.A OG1 TYR 200.A O no hydrogen 2.841 N/A ALA 205.A N VAL 201.A O no hydrogen 3.142 N/A GLU 206.A N ARG 202.A O no hydrogen 3.162 N/A LEU 207.A N LYS 203.A O no hydrogen 3.299 N/A ALA 208.A N THR 204.A O no hydrogen 3.197 N/A THR 209.A N ALA 205.A O no hydrogen 3.288 N/A THR 209.A OG1 GLU 206.A O no hydrogen 2.608 N/A GLN 210.A N GLU 206.A O no hydrogen 3.292 N/A PHE 211.A N LEU 207.A O no hydrogen 2.858 N/A PHE 211.A N ALA 208.A O no hydrogen 3.221 N/A PHE 212.A N ALA 208.A O no hydrogen 2.716 N/A ASN 214.A N GLN 219.A O no hydrogen 3.339 N/A ALA 216.A N ASN 214.A OD1 no hydrogen 2.931 N/A THR 217.A OG1 GLN 219.A OE1 no hydrogen 3.072 N/A SER 218.A N THR 217.A OG1 no hydrogen 2.647 N/A SER 218.A OG GLN 219.A OE1 no hydrogen 2.657 N/A ASN 221.A N PHE 212.A O no hydrogen 3.272 N/A ASN 221.A ND2 PHE 211.A O no hydrogen 3.638 N/A ALA 223.A N LYS 144.A O no hydrogen 2.528 N/A ILE 226.A N GLY 146.A O no hydrogen 3.003 N/A LEU 227.A N ASN 253.A O no hydrogen 3.224 N/A ALA 228.A N ILE 148.A O no hydrogen 2.854 N/A LYS 234.A NZ GLY 229.A O no hydrogen 3.137 N/A LYS 234.A NZ ASP 256.A OD1 no hydrogen 2.705 N/A LEU 237.A N PHE 233.A O no hydrogen 2.737 N/A SER 238.A N LYS 234.A O no hydrogen 3.002 N/A GLN 239.A N THR 235.A O no hydrogen 3.161 N/A SER 240.A N LEU 237.A O no hydrogen 3.055 N/A SER 240.A OG GLU 236.A O no hydrogen 2.489 N/A PHE 243.A N SER 240.A O no hydrogen 3.085 N/A ARG 246.A N ASP 244.A OD1 no hydrogen 2.955 N/A GLN 248.A NE2 SER 238.A O no hydrogen 2.875 N/A GLN 248.A NE2 SER 240.A O no hydrogen 3.464 N/A CYS 249.A SG GLN 245.A O no hydrogen 3.884 N/A CYS 249.A SG ARG 246.A O no hydrogen 3.148 N/A LEU 252.A N LEU 225.A O no hydrogen 3.128 N/A VAL 255.A N LEU 227.A O no hydrogen 2.944 N/A VAL 257.A N GLY 229.A O no hydrogen 3.201 N/A SER 258.A N GLN 267.A OE1 no hydrogen 3.094 N/A SER 258.A OG GLN 267.A OE1 no hydrogen 3.424 N/A GLY 264.A N GLY 260.A O no hydrogen 2.602 N/A PHE 265.A N GLY 261.A O no hydrogen 2.944 N/A ASN 266.A N GLU 262.A O no hydrogen 3.150 N/A ASN 266.A ND2 GLU 262.A O no hydrogen 3.227 N/A GLN 267.A N SER 263.A O no hydrogen 3.183 N/A ALA 268.A N GLY 264.A O no hydrogen 2.693 N/A ILE 269.A N PHE 265.A O no hydrogen 3.084 N/A GLU 270.A N ASN 266.A O no hydrogen 3.053 N/A LEU 271.A N GLN 267.A O no hydrogen 3.146 N/A SER 272.A N ALA 268.A O no hydrogen 3.155 N/A SER 272.A N ILE 269.A O no hydrogen 3.354 N/A SER 272.A OG ALA 268.A O no hydrogen 2.955 N/A SER 272.A OG ILE 269.A O no hydrogen 3.556 N/A LEU 276.A N SER 272.A O no hydrogen 3.077 N/A ALA 277.A N ALA 273.A O no hydrogen 2.953 N/A ALA 277.A N GLU 274.A O no hydrogen 3.170 N/A ASN 278.A N GLU 274.A O no hydrogen 3.186 N/A ILE 282.A N ASN 278.A O no hydrogen 3.288 N/A GLN 283.A N LYS 280.A O no hydrogen 2.359 N/A GLU 284.A N LYS 280.A O no hydrogen 3.031 N/A LYS 285.A N PHE 281.A O no hydrogen 3.000 N/A LEU 287.A N GLU 284.A O no hydrogen 3.261 N/A ILE 288.A N GLU 284.A O no hydrogen 3.313 N/A GLY 289.A N LYS 285.A O no hydrogen 3.259 N/A LYS 290.A N LYS 286.A O no hydrogen 3.303 N/A TYR 291.A N LEU 287.A O no hydrogen 2.836 N/A TYR 291.A OH VAL 303.A O no hydrogen 2.853 N/A PHE 292.A N ILE 288.A O no hydrogen 2.729 N/A GLU 293.A N GLY 289.A O no hydrogen 3.112 N/A GLU 294.A N GLU 294.A OE1 no hydrogen 2.744 N/A ILE 295.A N PHE 292.A O no hydrogen 3.261 N/A SER 296.A OG GLU 293.A O no hydrogen 2.863 N/A ASP 298.A N GLU 294.A O no hydrogen 2.802 N/A THR 309.A N GLY 305.A O no hydrogen 3.176 N/A THR 309.A OG1 GLY 305.A O no hydrogen 2.050 N/A THR 309.A OG1 VAL 306.A O no hydrogen 3.153 N/A LEU 310.A N VAL 306.A O no hydrogen 2.844 N/A LYS 311.A NZ GLU 314.A OE2 no hydrogen 2.323 N/A ALA 312.A N ASP 308.A O no hydrogen 2.920 N/A GLU 314.A N LYS 311.A O no hydrogen 3.012 N/A THR 320.A N ILE 413.A O no hydrogen 2.985 N/A LEU 321.A N THR 389.A O no hydrogen 3.086 N/A MET 322.A N GLY 411.A O no hydrogen 2.836 N/A VAL 323.A N GLU 391.A O no hydrogen 3.071 N/A ASN 330.A N LEU 347.A O no hydrogen 2.788 N/A ASN 330.A ND2 GLU 352.A OE2 no hydrogen 3.121 N/A PHE 332.A N LYS 345.A O no hydrogen 2.724 N/A LEU 334.A N ILE 343.A O no hydrogen 2.757 N/A HIS 336.A N GLY 340.A O no hydrogen 3.177 N/A SER 337.A OG GLU 366.A O no hydrogen 3.459 N/A LYS 345.A N PHE 332.A O no hydrogen 3.190 N/A LEU 347.A N ASN 330.A O no hydrogen 2.654 N/A LYS 349.A NZ ASP 328.A OD2 no hydrogen 2.747 N/A LYS 349.A NZ ASN 348.A OD1 no hydrogen 2.281 N/A SER 356.A N GLN 355.A OE1 no hydrogen 3.064 N/A ARG 359.A NH1 GLU 366.A OE2 no hydrogen 3.524 N/A LEU 367.A N PHE 358.A O no hydrogen 3.134 N/A THR 373.A N ARG 331.A O no hydrogen 2.947 N/A THR 373.A OG1 ARG 331.A O no hydrogen 3.080 N/A TRP 378.A N SER 374.A O no hydrogen 2.606 N/A PHE 379.A N LEU 375.A O no hydrogen 2.805 N/A ASN 381.A N GLU 377.A O no hydrogen 2.740 N/A GLU 382.A N TRP 378.A O no hydrogen 2.954 N/A CYS 388.A SG TYR 383.A O no hydrogen 3.849 N/A THR 389.A OG1 GLU 319.A O no hydrogen 2.735 N/A VAL 393.A N VAL 323.A O no hydrogen 3.157 N/A ASN 395.A ND2 GLY 400.A O no hydrogen 2.243 N/A LYS 396.A NZ THR 394.A O no hydrogen 3.028 N/A GLN 398.A N SER 397.A OG no hydrogen 2.779 N/A SER 401.A N SER 397.A O no hydrogen 2.909 N/A SER 401.A OG SER 397.A O no hydrogen 3.245 N/A SER 401.A OG GLN 398.A O no hydrogen 2.625 N/A GLN 402.A N GLN 398.A O no hydrogen 2.837 N/A PHE 403.A N GLU 399.A O no hydrogen 3.215 N/A CYS 404.A N SER 401.A O no hydrogen 3.197 N/A CYS 404.A SG ASN 395.A OD1 no hydrogen 3.527 N/A ARG 405.A N SER 401.A O no hydrogen 2.964 N/A GLY 406.A N GLN 402.A O no hydrogen 2.922 N/A GLY 411.A N MET 322.A O no hydrogen 2.933 N/A ILE 413.A N THR 320.A O no hydrogen 2.970 N/A LEU 414.A N LYS 301.A O no hydrogen 3.286 N/A ARG 421.A NH1 ARG 421.A O no hydrogen 2.877 N/A SER 422.A N ASP 419.A O no hydrogen 2.886 N/A SER 422.A OG PHE 423.A O no hydrogen 2.250 N/A SER 422.A OG ASP 425.A OD1 no hydrogen 3.156 N/A VAL 432.A N GLU 430.A O no hydrogen 2.940 N/A SER 436.A OG ASP 437.A O no hydrogen 3.539 N/A