Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 8iu7_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): PHE 5.A N ASN 2.A OD1 no hydrogen 2.688 N/A GLN 6.A N ASN 2.A O no hydrogen 3.259 N/A GLN 6.A NE2 GLU 1.A O no hydrogen 3.056 N/A GLY 7.A N LEU 3.A O no hydrogen 3.115 N/A HIS 8.A N TYR 4.A O no hydrogen 2.919 N/A MET 9.A N PHE 5.A O no hydrogen 2.855 N/A ILE 10.A N GLN 6.A O no hydrogen 3.061 N/A SER 11.A N GLY 7.A O no hydrogen 3.027 N/A THR 12.A N HIS 8.A O no hydrogen 2.803 N/A THR 12.A OG1 HIS 8.A O no hydrogen 2.620 N/A LEU 13.A N MET 9.A O no hydrogen 2.790 N/A ASN 14.A N ILE 10.A O no hydrogen 2.871 N/A GLU 15.A N SER 11.A O no hydrogen 2.765 N/A ILE 16.A N THR 12.A O no hydrogen 2.897 N/A MET 17.A N LEU 13.A O no hydrogen 3.199 N/A LYS 18.A N ASN 14.A O no hydrogen 3.176 N/A CYS 19.A N GLU 15.A O no hydrogen 2.971 N/A CYS 19.A SG GLU 15.A O no hydrogen 3.297 N/A ILE 20.A N ILE 16.A O no hydrogen 2.874 N/A GLU 21.A N MET 17.A O no hydrogen 2.699 N/A ASP 22.A N LYS 18.A O no hydrogen 2.858 N/A ASN 23.A N ILE 20.A O no hydrogen 3.154 N/A ASN 23.A ND2 CYS 19.A O no hydrogen 2.852 N/A THR 25.A OG1 ASP 24.A OD2 no hydrogen 3.221 N/A ILE 26.A N GLN 57.A O no hydrogen 2.912 N/A ILE 27.A N LEU 86.A O no hydrogen 2.922 N/A ILE 28.A N PHE 59.A O no hydrogen 2.897 N/A HIS 29.A N ILE 88.A O no hydrogen 2.790 N/A ARG 30.A NH1 HIS 31.A O no hydrogen 2.976 N/A ARG 30.A NH1 ASP 99.A OD2 no hydrogen 2.848 N/A ARG 30.A NH2 GLU 63.A O no hydrogen 2.540 N/A HIS 31.A ND1 VAL 32.A O no hydrogen 2.825 N/A VAL 32.A N ARG 97.A O no hydrogen 2.814 N/A ARG 33.A NH1 GLU 267.A OE2 no hydrogen 2.867 N/A ARG 33.A NH2 GLU 267.A OE1 no hydrogen 3.011 N/A ARG 33.A NH2 GLU 267.A OE2 no hydrogen 3.029 N/A ALA 38.A N ASP 35.A OD1 no hydrogen 2.845 N/A TYR 39.A N ASP 35.A O no hydrogen 3.156 N/A GLY 40.A N PRO 36.A O no hydrogen 2.700 N/A SER 41.A N ASP 37.A O no hydrogen 2.866 N/A SER 41.A OG ASP 37.A O no hydrogen 2.788 N/A SER 41.A OG ALA 38.A O no hydrogen 3.208 N/A GLN 42.A N ALA 38.A O no hydrogen 3.136 N/A GLN 42.A NE2 ILE 28.A O no hydrogen 2.921 N/A GLN 42.A NE2 VAL 61.A O no hydrogen 2.766 N/A LEU 43.A N TYR 39.A O no hydrogen 2.927 N/A GLY 44.A N GLY 40.A O no hydrogen 2.888 N/A LEU 45.A N SER 41.A O no hydrogen 2.984 N/A LYS 46.A N GLN 42.A O no hydrogen 2.950 N/A LYS 46.A NZ ASP 75.A OD1 no hydrogen 3.559 N/A LYS 46.A NZ ASP 75.A OD2 no hydrogen 2.862 N/A TYR 47.A N LEU 43.A O no hydrogen 2.891 N/A TYR 48.A N GLY 44.A O no hydrogen 2.933 N/A TYR 48.A OH ASP 147.A OD2 no hydrogen 2.721 N/A ILE 49.A N LEU 45.A O no hydrogen 2.938 N/A GLN 50.A N LYS 46.A O no hydrogen 2.894 N/A GLN 50.A NE2 VAL 58.A O no hydrogen 3.453 N/A GLN 51.A N TYR 47.A O no hydrogen 2.986 N/A LYS 52.A N TYR 48.A O no hydrogen 2.942 N/A LYS 52.A NZ ASP 147.A OD1 no hydrogen 3.337 N/A LYS 52.A NZ ASP 147.A OD2 no hydrogen 2.794 N/A PHE 53.A N ILE 49.A O no hydrogen 2.664 N/A LYS 56.A N PHE 53.A O no hydrogen 3.178 N/A LYS 56.A NZ GLU 21.A O no hydrogen 2.992 N/A LYS 56.A NZ ASN 23.A O no hydrogen 2.827 N/A GLN 57.A N ASP 24.A O no hydrogen 2.836 N/A PHE 59.A N ILE 26.A O no hydrogen 2.898 N/A ALA 60.A N ASP 75.A OD2 no hydrogen 2.886 N/A VAL 61.A N ILE 28.A O no hydrogen 3.211 N/A GLU 63.A N ASP 99.A OD1 no hydrogen 2.789 N/A GLU 65.A N TYR 39.A OH no hydrogen 2.929 N/A LEU 68.A N GLU 65.A O no hydrogen 2.988 N/A SER 69.A N SER 66.A O no hydrogen 3.446 N/A SER 69.A OG GLU 65.A O no hydrogen 3.334 N/A ILE 71.A N LEU 68.A O no hydrogen 2.905 N/A GLY 72.A N SER 69.A O no hydrogen 3.242 N/A ASP 75.A N ALA 60.A O no hydrogen 2.614 N/A THR 81.A N ASP 78.A O no hydrogen 3.057 N/A THR 81.A OG1 ASP 78.A O no hydrogen 3.135 N/A TYR 82.A N ASP 79.A O no hydrogen 3.450 N/A TYR 82.A OH HIS 29.A NE2 no hydrogen 2.976 N/A GLN 83.A N LYS 80.A O no hydrogen 3.147 N/A GLN 83.A NE2 ASP 84.A OD2 no hydrogen 3.438 N/A ALA 85.A N TYR 82.A O no hydrogen 2.845 N/A LEU 86.A N THR 25.A O no hydrogen 3.010 N/A VAL 87.A N LYS 108.A O no hydrogen 2.942 N/A ILE 88.A N ILE 27.A O no hydrogen 2.970 N/A VAL 89.A N ILE 110.A O no hydrogen 2.744 N/A CYS 90.A N HIS 29.A O no hydrogen 2.919 N/A ASP 91.A N ILE 112.A O no hydrogen 2.972 N/A THR 92.A OG1 CYS 90.A O no hydrogen 2.786 N/A ALA 95.A N ASP 119.A OD2 no hydrogen 3.019 N/A ARG 97.A N ASN 94.A O no hydrogen 2.895 N/A ILE 98.A N ALA 95.A O no hydrogen 3.098 N/A ASP 99.A N ARG 30.A O no hydrogen 2.968 N/A ARG 102.A N ASP 100.A OD1 no hydrogen 3.202 N/A ARG 102.A NE ASP 100.A OD1 no hydrogen 3.061 N/A ARG 102.A NH1 ILE 77.A O no hydrogen 3.001 N/A ARG 102.A NH1 ASP 79.A OD1 no hydrogen 3.129 N/A ARG 102.A NH2 ASP 100.A OD2 no hydrogen 3.076 N/A TYR 103.A N ASP 100.A O no hydrogen 3.309 N/A SER 104.A OG GLU 101.A O no hydrogen 3.536 N/A THR 105.A N ARG 102.A O no hydrogen 2.838 N/A THR 105.A OG1 ARG 102.A O no hydrogen 2.875 N/A ARG 107.A N ALA 85.A O no hydrogen 3.020 N/A ARG 107.A NH2 ASP 84.A O no hydrogen 3.022 N/A LEU 109.A N ASP 123.A OD1 no hydrogen 2.915 N/A ILE 110.A N VAL 87.A O no hydrogen 2.769 N/A LYS 111.A N ILE 124.A O no hydrogen 2.849 N/A LYS 111.A NZ ASP 119.A O no hydrogen 2.635 N/A LYS 111.A NZ GLN 120.A OE1 no hydrogen 3.251 N/A ILE 112.A N VAL 89.A O no hydrogen 2.971 N/A ASP 113.A N LEU 126.A O no hydrogen 2.949 N/A HIS 114.A N ASP 113.A OD1 no hydrogen 2.659 N/A HIS 114.A ND1 THR 134.A OG1 no hydrogen 2.993 N/A HIS 115.A N ASP 113.A OD1 no hydrogen 3.212 N/A TYR 121.A OH THR 92.A O no hydrogen 2.489 N/A GLY 122.A N ASN 125.A OD1 no hydrogen 2.876 N/A ASP 123.A N LEU 109.A O no hydrogen 2.741 N/A ILE 124.A N LEU 109.A O no hydrogen 3.347 N/A ASN 125.A ND2 GLY 122.A O no hydrogen 3.012 N/A LEU 126.A N LYS 111.A O no hydrogen 2.662 N/A ASN 128.A N ASP 113.A O no hydrogen 3.094 N/A ASN 130.A N ASN 128.A OD1 no hydrogen 3.150 N/A ALA 131.A N ASN 128.A O no hydrogen 3.198 N/A SER 132.A N GLU 136.A OE1 no hydrogen 3.290 N/A SER 132.A OG SER 133.A OG no hydrogen 2.864 N/A SER 132.A OG GLU 136.A OE1 no hydrogen 2.707 N/A SER 133.A OG SER 132.A OG no hydrogen 2.864 N/A THR 134.A N ASP 37.A OD2 no hydrogen 2.876 N/A THR 134.A OG1 ASP 37.A OD2 no hydrogen 3.499 N/A THR 134.A OG1 ASP 91.A OD1 no hydrogen 2.821 N/A THR 134.A OG1 HIS 114.A ND1 no hydrogen 2.993 N/A SER 135.A N ASP 37.A OD1 no hydrogen 2.794 N/A SER 135.A OG ASP 37.A OD1 no hydrogen 2.683 N/A GLU 136.A N SER 133.A OG no hydrogen 3.096 N/A ILE 137.A N SER 133.A O no hydrogen 3.367 N/A ILE 138.A N THR 134.A O no hydrogen 3.002 N/A TYR 139.A N SER 135.A O no hydrogen 3.126 N/A ASP 140.A N GLU 136.A O no hydrogen 2.966 N/A LEU 141.A N ILE 137.A O no hydrogen 2.852 N/A ILE 142.A N ILE 138.A O no hydrogen 3.039 N/A SER 143.A N TYR 139.A O no hydrogen 2.823 N/A SER 143.A OG TYR 139.A O no hydrogen 2.964 N/A SER 143.A OG GLU 148.A OE2 no hydrogen 2.873 N/A HIS 144.A N ASP 140.A O no hydrogen 2.941 N/A HIS 144.A NE2 ASN 14.A OD1 no hydrogen 3.253 N/A PHE 145.A N LEU 141.A O no hydrogen 3.317 N/A PHE 145.A N ILE 142.A O no hydrogen 3.169 N/A ASN 146.A N SER 143.A O no hydrogen 3.148 N/A ASP 147.A N ILE 142.A O no hydrogen 3.106 N/A ILE 150.A N ASP 147.A O no hydrogen 3.050 N/A LYS 153.A NZ ASP 190.A O no hydrogen 3.368 N/A ILE 155.A N ASN 152.A OD1 no hydrogen 2.917 N/A ALA 156.A N ASN 152.A O no hydrogen 3.064 N/A SER 157.A N LYS 153.A O no hydrogen 2.941 N/A SER 157.A OG LYS 153.A O no hydrogen 2.666 N/A VAL 158.A N ASP 154.A O no hydrogen 3.120 N/A LEU 159.A N ILE 155.A O no hydrogen 2.994 N/A TYR 160.A N ALA 156.A O no hydrogen 2.927 N/A LEU 161.A N SER 157.A O no hydrogen 3.077 N/A GLY 162.A N VAL 158.A O no hydrogen 3.158 N/A ILE 163.A N LEU 159.A O no hydrogen 3.042 N/A VAL 164.A N TYR 160.A O no hydrogen 2.972 N/A GLY 165.A N LEU 161.A O no hydrogen 2.752 N/A ASP 166.A N GLY 162.A O no hydrogen 3.236 N/A THR 167.A N ILE 163.A O no hydrogen 3.079 N/A THR 167.A OG1 ILE 163.A O no hydrogen 2.674 N/A THR 167.A OG1 VAL 164.A O no hydrogen 3.487 N/A ARG 169.A N VAL 164.A O no hydrogen 2.876 N/A PHE 170.A N THR 167.A OG1 no hydrogen 2.927 N/A LEU 171.A N THR 167.A O no hydrogen 2.747 N/A PHE 172.A N THR 167.A O no hydrogen 2.907 N/A ASN 173.A ND2 GLY 279.A O no hydrogen 3.532 N/A ASN 174.A ND2 SER 132.A O no hydrogen 3.135 N/A ASN 174.A ND2 ASP 166.A O no hydrogen 2.854 N/A THR 175.A N PHE 172.A O no hydrogen 3.112 N/A THR 175.A OG1 PHE 172.A O no hydrogen 3.060 N/A SER 176.A N THR 179.A OG1 no hydrogen 2.949 N/A SER 176.A OG THR 179.A OG1 no hydrogen 2.963 N/A HIS 178.A NE2 ASP 140.A OD1 no hydrogen 2.687 N/A THR 179.A N SER 176.A OG no hydrogen 2.971 N/A THR 179.A OG1 GLU 136.A OE1 no hydrogen 2.811 N/A THR 179.A OG1 SER 176.A OG no hydrogen 2.963 N/A MET 180.A N SER 176.A O no hydrogen 3.114 N/A GLU 181.A N GLU 177.A O no hydrogen 3.002 N/A ILE 182.A N HIS 178.A O no hydrogen 3.012 N/A ALA 183.A N THR 179.A O no hydrogen 3.028 N/A GLY 184.A N MET 180.A O no hydrogen 2.828 N/A LYS 185.A N GLU 181.A O no hydrogen 3.093 N/A LYS 185.A NZ GLU 148.A OE1 no hydrogen 3.349 N/A LYS 185.A NZ GLU 148.A OE2 no hydrogen 3.378 N/A LEU 186.A N ILE 182.A O no hydrogen 2.929 N/A ILE 187.A N ALA 183.A O no hydrogen 3.027 N/A GLY 188.A N GLY 184.A O no hydrogen 2.991 N/A HIS 189.A N LEU 186.A O no hydrogen 3.114 N/A HIS 189.A ND1 LYS 185.A O no hydrogen 3.066 N/A ASP 190.A N ILE 187.A O no hydrogen 3.021 N/A LEU 196.A N ASP 192.A O no hydrogen 3.173 N/A LEU 197.A N HIS 193.A O no hydrogen 2.849 N/A ASN 198.A N ASN 194.A O no hydrogen 2.913 N/A LYS 199.A N ALA 195.A O no hydrogen 2.985 N/A LYS 199.A NZ GLU 202.A OE2 no hydrogen 3.520 N/A MET 200.A N LEU 196.A O no hydrogen 2.925 N/A MET 201.A N LEU 197.A O no hydrogen 2.940 N/A GLU 202.A N LYS 199.A O no hydrogen 3.369 N/A LYS 206.A N ASP 204.A OD1 no hydrogen 2.881 N/A MET 207.A N ASP 204.A O no hydrogen 3.019 N/A LEU 208.A N PRO 205.A O no hydrogen 3.247 N/A GLN 211.A N MET 207.A O no hydrogen 3.251 N/A GLN 211.A NE2 THR 251.A OG1 no hydrogen 3.335 N/A GLY 212.A N LEU 208.A O no hydrogen 2.966 N/A TYR 213.A N PRO 209.A O no hydrogen 3.110 N/A VAL 214.A N PHE 210.A O no hydrogen 3.148 N/A LEU 215.A N GLN 211.A O no hydrogen 3.082 N/A GLN 216.A N GLY 212.A O no hydrogen 3.009 N/A GLN 216.A N TYR 213.A O no hydrogen 3.141 N/A HIS 217.A N VAL 214.A O no hydrogen 3.231 N/A GLU 219.A N GLN 227.A O no hydrogen 2.937 N/A MET 221.A N PHE 225.A O no hydrogen 2.709 N/A GLY 224.A N MET 221.A O no hydrogen 2.901 N/A CYS 226.A N ILE 260.A O no hydrogen 2.829 N/A CYS 226.A SG GLU 219.A O no hydrogen 3.335 N/A GLN 227.A N GLU 219.A O no hydrogen 2.918 N/A GLN 227.A NE2 GLU 219.A OE1 no hydrogen 2.223 N/A VAL 228.A N VAL 262.A O no hydrogen 3.148 N/A ILE 230.A N ALA 264.A O no hydrogen 2.745 N/A VAL 234.A N THR 231.A O no hydrogen 3.099 N/A VAL 234.A N THR 231.A OG1 no hydrogen 3.353 N/A LEU 235.A N THR 231.A O no hydrogen 3.286 N/A GLU 236.A N GLU 232.A O no hydrogen 3.174 N/A GLN 237.A N ASP 233.A O no hydrogen 2.791 N/A PHE 238.A N VAL 234.A O no hydrogen 3.100 N/A GLY 239.A N GLU 236.A O no hydrogen 3.206 N/A ILE 240.A N LEU 235.A O no hydrogen 3.053 N/A GLN 241.A N GLU 244.A OE1 no hydrogen 2.694 N/A ALA 245.A N GLN 241.A O no hydrogen 2.939 N/A SER 246.A N PRO 242.A O no hydrogen 3.121 N/A SER 246.A OG PRO 242.A O no hydrogen 2.863 N/A GLN 247.A N GLU 244.A O no hydrogen 3.336 N/A GLN 247.A NE2 ASN 243.A O no hydrogen 2.900 N/A PHE 248.A N ALA 245.A O no hydrogen 3.192 N/A THR 251.A N PHE 248.A O no hydrogen 3.190 N/A THR 251.A OG1 PHE 248.A O no hydrogen 3.169 N/A ALA 253.A N ASN 250.A O no hydrogen 2.947 N/A ILE 255.A N ILE 252.A O no hydrogen 3.209 N/A LEU 258.A N ILE 255.A O no hydrogen 3.280 N/A LYS 259.A N GLY 224.A O no hydrogen 2.811 N/A ILE 260.A N GLY 224.A O no hydrogen 2.906 N/A TRP 261.A N ARG 276.A O no hydrogen 3.077 N/A TRP 261.A NE1 VAL 249.A O no hydrogen 3.057 N/A VAL 262.A N CYS 226.A O no hydrogen 3.172 N/A PHE 263.A N ARG 274.A O no hydrogen 2.951 N/A ALA 264.A N VAL 228.A O no hydrogen 2.995 N/A VAL 265.A N ARG 272.A O no hydrogen 3.081 N/A ASP 266.A N ILE 230.A O no hydrogen 2.989 N/A GLU 267.A N GLU 270.A O no hydrogen 2.755 N/A GLY 268.A N ASP 266.A OD1 no hydrogen 2.595 N/A ILE 271.A N VAL 303.A O no hydrogen 2.708 N/A ARG 272.A N VAL 265.A O no hydrogen 2.986 N/A CYS 273.A N VAL 301.A O no hydrogen 2.614 N/A CYS 273.A SG ILE 271.A O no hydrogen 3.614 N/A ARG 274.A N PHE 263.A O no hydrogen 2.888 N/A LEU 275.A N SER 299.A O no hydrogen 2.887 N/A ARG 276.A N TRP 261.A O no hydrogen 2.909 N/A SER 277.A N ASN 297.A O no hydrogen 3.339 N/A SER 277.A OG LEU 281.A O no hydrogen 3.377 N/A SER 277.A OG PRO 296.A O no hydrogen 3.445 N/A SER 277.A OG ASN 297.A OD1 no hydrogen 2.677 N/A LYS 278.A N LYS 259.A O no hydrogen 2.843 N/A LYS 278.A NZ ALA 253.A O no hydrogen 2.957 N/A ILE 283.A N PRO 296.A O no hydrogen 3.238 N/A ASN 284.A ND2 GLY 294.A O no hydrogen 2.687 N/A ALA 287.A N ILE 283.A O no hydrogen 2.974 N/A GLN 288.A N ASN 284.A O no hydrogen 2.925 N/A GLN 288.A NE2 ASP 285.A O no hydrogen 3.404 N/A ASP 289.A N ASP 285.A O no hydrogen 2.916 N/A PHE 290.A N ALA 287.A O no hydrogen 2.974 N/A GLY 291.A N GLN 288.A O no hydrogen 3.083 N/A GLY 292.A N ALA 287.A O no hydrogen 2.689 N/A GLY 293.A N GLY 300.A O no hydrogen 3.128 N/A HIS 295.A N ALA 298.A O no hydrogen 2.920 N/A ASN 297.A N HIS 295.A ND1 no hydrogen 3.319 N/A ASN 297.A ND2 GLY 279.A O no hydrogen 3.252 N/A ALA 298.A N HIS 295.A O no hydrogen 3.108 N/A SER 299.A N LEU 275.A O no hydrogen 3.185 N/A SER 299.A OG ASN 284.A OD1 no hydrogen 1.784 N/A SER 299.A OG HIS 295.A O no hydrogen 2.304 N/A GLY 300.A N GLY 293.A O no hydrogen 3.130 N/A VAL 301.A N CYS 273.A O no hydrogen 2.931 N/A SER 302.A OG GLU 270.A OE2 no hydrogen 3.470 N/A VAL 303.A N ILE 271.A O no hydrogen 2.936 N/A ASP 304.A N GLU 308.A OE1 no hydrogen 2.990 N/A GLU 308.A N SER 305.A OG no hydrogen 3.005 N/A PHE 309.A N SER 305.A O no hydrogen 3.110 N/A GLU 310.A N TRP 306.A O no hydrogen 3.089 N/A GLN 311.A N GLU 308.A O no hydrogen 3.170 N/A LEU 312.A N GLU 308.A O no hydrogen 3.093 N/A ALA 313.A N PHE 309.A O no hydrogen 2.732 N/A THR 314.A N GLU 310.A O no hydrogen 2.893 N/A THR 314.A OG1 GLU 310.A O no hydrogen 3.466 N/A ALA 315.A N GLN 311.A O no hydrogen 2.964 N/A LEU 316.A N LEU 312.A O no hydrogen 3.055 N/A ARG 317.A N ALA 313.A O no hydrogen 2.854 N/A ARG 317.A NE ASP 223.A OD1 no hydrogen 3.515 N/A THR 318.A N THR 314.A O no hydrogen 3.204 N/A THR 318.A N ALA 315.A O no hydrogen 3.251 N/A THR 318.A OG1 ALA 315.A O no hydrogen 2.664 N/A LYS 319.A N LEU 316.A O no hydrogen 3.194 N/A LYS 319.A NZ ILE 282.A O no hydrogen 3.536 N/A LYS 319.A NZ ASP 285.A OD2 no hydrogen 2.915 N/A LEU 320.A N ARG 317.A O no hydrogen 3.124 N/A