|
99
|
251
|
5b41A |
Crystal structure of vdr-lbd complexed with 2-methylidene-19-nor-1a,25-dihydroxyvitamin d3 |
|
100
|
260
|
5b5bA |
Crystal structure of vdr-lbd complexed with 2-methylidene-26,27-diphenyl-19-nor-1,25-dihydroxyvitamin d3 |
|
90
|
250
|
5aauA |
Optimization of a novel binding motif to to (e)-3-(3,5-difluoro-4-((1r,3r)-2-(2-fluoro-2-methylpropyl)-3-methyl-2,3,4,9-tetrahydro-1h- pyrido(3,4-b)indol-1-yl)phenyl)acrylic acid (azd9496), a potent and orally bioavailable selective estrogen receptor downregulator and antagonist |
|
74
|
240
|
5aavB |
Optimization of a novel binding motif to to (e)-3-(3,5-difluoro-4-((1r,3r)-2-(2-fluoro-2-methylpropyl)-3-methyl-2,3,4,9-tetrahydro-1h- pyrido(3,4-b)indol-1-yl)phenyl)acrylic acid (azd9496), a potent and orally bioavailable selective estrogen receptor downregulator and antagonist |
|
82
|
239
|
5accA |
A novel oral selective estrogen receptor down-regulator, azd9496, drives tumour growth inhibition in estrogen receptor positive and esr1 mutant models |
|
85
|
249
|
5aavA |
Optimization of a novel binding motif to to (e)-3-(3,5-difluoro-4-((1r,3r)-2-(2-fluoro-2-methylpropyl)-3-methyl-2,3,4,9-tetrahydro-1h- pyrido(3,4-b)indol-1-yl)phenyl)acrylic acid (azd9496), a potent and orally bioavailable selective estrogen receptor downregulator and antagonist |
|
88
|
244
|
4zntA |
Crystal structure of the er-alpha ligand-binding domain (y537s) in complex with a 3-bromo-substituted obhs derivative |
|
90
|
241
|
4zi1A |
Human estrogen receptor beta ligand-binding domain in complex with kb095285 and cia12 coactivator peptide |
|
90
|
250
|
4zn9A |
Crystal structure of the er-alpha ligand-binding domain (y537s) in complex with oxabicyclic heptene sulfonate (obhs) |
|
84
|
219
|
4zjwA |
Rorgamma in complex with inverse agonist 16 |
|
77
|
217
|
4zjrA |
Rorgamma in complex with inverse agonist 48 |
|
90
|
244
|
4zn7A |
Crystal structure of the er-alpha ligand-binding domain (y537s) in complex with diethylstilbestrol |
|
99
|
259
|
4ymqA |
X-ray co-structure of nuclear receptor ror-gammat + src2 peptide with a benzothiadiazole dioxide inverse agonist |
|
98
|
272
|
4yt1A |
Human ppar gamma ligand binding domain in complex with a gammma selective synthetic partial agonist mekt76 |
|
96
|
243
|
4ypqA |
Crystal structure of the ror(gamma)t ligand binding domain in complex with 4-(1-(2-chloro-6-(trifluoromethyl)benzoyl)-1h-indazol-3-yl)benzoic acid |
|
98
|
271
|
4f9mA |
Crystal structure of the ppargamma-lbd complexed with a cercosporamide derivative modulator |
|
80
|
231
|
4pojA |
Crystal structure of human retinoid x receptor alpha-ligand binding domain complex with 7-methyl uab30 and the coactivator peptide grip-1 |
|
93
|
271
|
4emaA |
Human peroxisome proliferator-activated receptor gamma in complex with rosiglitazone |
|
97
|
268
|
4e4qA |
Crystal structure of ppargamma with the ligand fs214 |
|
86
|
268
|
4e4kA |
Crystal structure of ppargamma with the ligand jo21 |
|
91
|
239
|
4dorA |
Human nuclear receptor liver receptor homologue-1, lrh-1, in its apo state bound to a fragment of human shp box1 |
|
93
|
247
|
4e2jA |
X-ray crystal structure of the ancestral glucocorticoid receptor 2 ligand binding domain in complex with mometasone furoate and tif-2 coactivator fragment |
|
94
|
242
|
4dosA |
Human nuclear receptor liver receptor homologue-1, lrh-1, bound to dlpc and a fragment of tif-2 |
|
100
|
271
|
4em9A |
Human ppar gamma in complex with nonanoic acids |
|
92
|
234
|
4dqmA |
Revealing a marine natural product as a novel agonist for retinoic acid receptors with a unique binding mode and antitumor activity |
|
92
|
241
|
4dk8A |
Crystal structure of lxr ligand binding domain in complex with partial agonist 5 |
|
91
|
245
|
4dmaA |
Crystal structure of era lbd in complex with ru100132 |
|
93
|
240
|
4dm6A |
Crystal structure of rarb lbd homodimer in complex with ttnpb |
|
82
|
243
|
4dk7A |
Crystal structure of lxr ligand binding domain in complex with full agonist 1 |
|
81
|
240
|
4dm8A |
Crystal structure of rarb lbd in complex with 9cis retinoic acid |
|
101
|
247
|
4csjA |
The discovery of potent selective glucocorticoid receptor modulators, suitable for inhalation |
|
97
|
264
|
4ci4A |
Structural basis for gl479 a dual peroxisome proliferator-activated receptor alpha agonist |
|
100
|
263
|
4bcrA |
Structure of pparalpha in complex with wy14643 |
|
52
|
202
|
4b7wA |
Ligand binding domain human hepatocyte nuclear factor 4alpha: apo form |
|
96
|
250
|
4apuA |
Pr x-ray structures in agonist conformations reveal two different mechanisms for partial agonism in 11beta-substituted steroids |
|
103
|
250
|
3zraA |
Structural basis for agonism and antagonism for a set of chemically related progesterone receptor modulators |
|
102
|
275
|
4a4vA |
Ligand binding domain of human ppar gamma in complex with amorfrutin 2 |
|
106
|
250
|
3zr7A |
Structural basis for agonism and antagonism for a set of chemically related progesterone receptor modulators |
|
105
|
275
|
4a4wA |
Ligand binding domain of human ppar gamma in complex with amorfrutin b |
|
98
|
250
|
3zqtA |
Targeting the binding function 3 site of the androgen receptor through in silico molecular modeling |
|
96
|
250
|
4a2jA |
Pr x-ray structures in agonist conformations reveal two different mechanisms for partial agonism in 11beta-substituted steroids |
|
104
|
250
|
3zrbA |
Structural basis for agonism and antagonism for a set of chemically related progesterone receptor modulators |
|
100
|
268
|
3x1hA |
Hppargamma ligand binding domain in complex with 5-oxo-tricosahexaenoic acid |
|
98
|
251
|
3wtqA |
Crystal structure of vdr-lbd complexed with 22s-butyl-2-methylidene-19-nor-1a,25-dihydroxyvitamin d3 |
|
101
|
272
|
3wj5A |
Crystal structure of ppargamma ligand binding domain in complex with triphenyltin |
|
100
|
251
|
3w5qA |
Crystal structure of complexes of vitamin d receptor ligand binding domain with lithocholic acid derivatives |
|
96
|
255
|
3wwrA |
Crystal structure of the human vitamin d receptor ligand binding domain complexed with 1-((((1s,2r,6r,z)-2,6-dihydroxy-4-((e)-2-((1r,3as,7ar)-1-((r)-6-hydroxy-6-methylheptan-2-yl)-7a-methylhexahydro-1h-inden-4(2h)-ylidene)ethylidene)-3-methylenecyclohexyl)oxy)methyl)cyclopropanecarbonitrile |
|
98
|
251
|
3w5pA |
Crystal structure of complexes of vitamin d receptor ligand binding domain with lithocholic acid derivatives |
|
98
|
249
|
3wfgA |
Mineralocorticoid receptor ligand-binding domain with compuond 2e |
|
93
|
270
|
3x1iA |
Hppargamma ligand binding domain in complex with 6-oxo-tetracosahexaenoic acid |
