|
86
|
318
|
6bh2A |
Linked kdm5a jmj domain bound to the inhibitor (r)-n-(1-(3-isopropyl-1h-pyrazole-5-carbonyl)pyrrolidin-3-yl)cyclopropanecarboxamide (compound n54) |
|
89
|
318
|
6bguA |
Linked kdm5a jmj domain bound to the inhibitor 2-((2-chlorophenyl)(propoxy)methyl)-1h-pyrrolo[3,2-b]pyridine (compound n9) |
|
86
|
318
|
6bgzA |
Linked kdm5a jmj domain bound to the inhibitor 2-((2-chlorophenyl)(2-(1-methyl-1h-imidazol-2-yl)ethoxy)methyl)-1h-pyrrolo[3,2-b]pyridine-7-carboxylic acid (compound n47) |
|
86
|
318
|
6bh1A |
Linked kdm5a jmj domain bound to the inhibitor (s)-2-((2-chlorophenyl)(2-(piperidin-1-yl)ethoxy)methyl)-1l2-pyrrolo[3,2-b]pyridine-7-carboxylic acid (compound n52) |
|
84
|
318
|
6bh4A |
Linked kdm5a jmj domain bound to the inhibitor 5-(1-(tert-butyl)-1h-pyrazol-4-yl)-6-isopropyl-7-oxo-4,7-dihydropyrazolo[1,5-a]pyrimidine-3-carbonitrile (compound n75/cpi-48) |
|
87
|
318
|
6bgwA |
Linked kdm5a jmj domain bound to the inhibitor 2-((2-chlorophenyl)(2-(4,4-difluoropiperidin-1-yl)ethoxy)methyl)-1h-pyrrolo[3,2-b]pyridine-7-carboxylic acid(compound n41) |
|
158
|
547
|
5ykoA |
Crystal structure of arabidopsis thaliana jmj14 catalytic domain in complex with nog and h3k4me3 peptide |
|
148
|
547
|
5yknA |
Crystal structure of arabidopsis thaliana jmj14 catalytic domain |
|
105
|
345
|
5vgiA |
Crystal structure of kdm4 with the small molecule inhibitor qc6352 |
|
108
|
350
|
5vmpA |
Crystal structure of human kdm4 with small molecule inhibitor qc5714 |
|
107
|
350
|
5f37A |
Crystal structure of human kdm4a in complex with compound 58 |
|
161
|
774
|
5cehA |
Structure of histone lysine demethylase kdm5a in complex with selective inhibitor |
|
145
|
462
|
5a3nA |
Crystal structure of human plu-1 (jarid1b) in complex with kdoam25a |
|
144
|
463
|
5a3pA |
Crystal structure of the catalytic domain of human plu1 (jarid1b). |
|
144
|
458
|
5a1fA |
Crystal structure of the catalytic domain of plu1 in complex with n-oxalylglycine. |
|
150
|
462
|
5a3tA |
Crystal structure of human plu-1 (jarid1b) in complex with kdm5-c49 (2-(((2-((2-(dimethylamino)ethyl)(ethyl)amino)-2-oxoethyl)amino)methyl) isonicotinic acid). |
|
109
|
349
|
4uraA |
Crystal structure of human jmjd2a in complex with compound 14a |
|
99
|
327
|
4d6sA |
Crystal structure of human jmjd2d in complex with n-oxalylglycine and bound 5,6-dimethylbenzimidazole |
|
100
|
323
|
4d6rA |
Crystal structure of human jmjd2d in complex with n-oxalylglycine and bound o-toluenesulfonamide |
|
104
|
330
|
4d6qA |
Crystal structure of human jmjd2d in complex with 2,4-pdca |
|
103
|
348
|
4bisA |
Jmjd2a complexed with 8-hydroxyquinoline-4-carboxylic acid |
|
107
|
348
|
4ai9A |
Jmjd2a complexed with daminozide |
|
106
|
345
|
3u4sA |
Histone lysine demethylase jmjd2a in complex with t11c peptide substrate crosslinked to n-oxalyl-d-cysteine |
|
107
|
351
|
3rvhA |
Crystal structure of jmjd2a complexed with inhibitor |
|
105
|
344
|
2q8eA |
Specificity and mechanism of jmjd2a, a trimethyllysine-specific histone demethylase |
|
106
|
345
|
2q8cA |
Crystal structure of jmjd2a in ternary complex with an histone h3k9me3 peptide and 2-oxoglutarate |
|
100
|
347
|
2q8dA |
Crystal structure of jmj2d2a in ternary complex with histone h3-k36me2 and succinate |
|
158
|
774
|
5v9pA |
Crystal structure of pyrrolidine amide inhibitor [(3s)-3-(4-bromo-1h-pyrazol-1-yl)pyrrolidin-1-yl][3-(propan-2-yl)-1h-pyrazol-5-yl]methanone (compound 35) in complex with kdm5a |
|
147
|
774
|
5v9tA |
Crystal structure of selective pyrrolidine amide kdm5a inhibitor n-{(3r)-1-[3-(propan-2-yl)-1h-pyrazole-5-carbonyl]pyrrolidin-3-yl}cyclopropanecarboxamide (compound 48) |
|
107
|
348
|
5tvrA |
Jmjd2a in complex with ni(ii) and alpha-ketoglutarate |
|
104
|
348
|
5tvsA |
Jmjd2a in complex with ni(ii) |
|
104
|
331
|
5pm1A |
Pandda analysis group deposition -- crystal structure of jmjd2d after initial refinement with no ligand modelled (structure 159) |
|
104
|
331
|
5phmA |
Pandda analysis group deposition -- crystal structure of jmjd2d in complex with n09455a |
|
103
|
331
|
5pn1A |
Pandda analysis group deposition -- crystal structure of jmjd2d after initial refinement with no ligand modelled (structure 195) |
|
104
|
331
|
5pkbA |
Pandda analysis group deposition -- crystal structure of jmjd2d after initial refinement with no ligand modelled (structure 96) |
|
103
|
331
|
5pmhA |
Pandda analysis group deposition -- crystal structure of jmjd2d after initial refinement with no ligand modelled (structure 175) |
|
104
|
331
|
5pj1A |
Pandda analysis group deposition -- crystal structure of jmjd2d after initial refinement with no ligand modelled (structure 50) |
|
104
|
331
|
5plyA |
Pandda analysis group deposition -- crystal structure of jmjd2d after initial refinement with no ligand modelled (structure 156) |
|
105
|
331
|
5pleA |
Pandda analysis group deposition -- crystal structure of jmjd2d after initial refinement with no ligand modelled (structure 135) |
|
104
|
331
|
5pifA |
Pandda analysis group deposition -- crystal structure of jmjd2d after initial refinement with no ligand modelled (structure 28) |
|
103
|
331
|
5pnwA |
Pandda analysis group deposition -- crystal structure of jmjd2d after initial refinement with no ligand modelled (structure 225) |
|
105
|
331
|
5pjtA |
Pandda analysis group deposition -- crystal structure of jmjd2d after initial refinement with no ligand modelled (structure 78) |
|
103
|
331
|
5phoA |
Pandda analysis group deposition -- crystal structure of jmjd2d after initial refinement with no ligand modelled (structure 1) |
|
104
|
331
|
5pmuA |
Pandda analysis group deposition -- crystal structure of jmjd2d after initial refinement with no ligand modelled (structure 188) |
|
103
|
331
|
5pnuA |
Pandda analysis group deposition -- crystal structure of jmjd2d after initial refinement with no ligand modelled (structure 223) |
|
103
|
331
|
5pjsA |
Pandda analysis group deposition -- crystal structure of jmjd2d after initial refinement with no ligand modelled (structure 77) |
|
104
|
331
|
5plhA |
Pandda analysis group deposition -- crystal structure of jmjd2d after initial refinement with no ligand modelled (structure 138) |
|
105
|
331
|
5ph0A |
Pandda analysis group deposition -- crystal structure of jmjd2d in complex with n09484a |
|
104
|
331
|
5pmmA |
Pandda analysis group deposition -- crystal structure of jmjd2d after initial refinement with no ligand modelled (structure 180) |
|
105
|
331
|
5pi0A |
Pandda analysis group deposition -- crystal structure of jmjd2d after initial refinement with no ligand modelled (structure 13) |
