129
|
323
|
3hdzA |
Identification, synthesis, and sar of amino substituted pyrido[3,2b]pryaziones as potent and selective pde5 inhibitors |
131
|
324
|
3hc8A |
Investigation of aminopyridiopyrazinones as pde5 inhibitors: evaluation of modifications to the central ring system. |
131
|
328
|
3dyqA |
Human phosphodiestrase 9 (inhibited by omitting divalent cation) in complex with cgmp |
129
|
328
|
3dy8A |
Human phosphodiesterase 9 in complex with product 5'-gmp (e+p complex) |
131
|
324
|
3dysA |
Human phosphodiestrase-5'gmp complex (ep), produced by soaking with 20mm cgmp+20 mm mncl2+20 mm mgcl2 for 2 hours, and flash-cooled to liquid nitrogen temperature when substrate was still abudant. |
133
|
328
|
3dylA |
Human phosphdiesterase 9 substrate complex (es complex) |
132
|
328
|
3dynA |
Human phosphodiestrase 9 in complex with cgmp (zn inhibited) |
49
|
171
|
3dbaA |
Crystal structure of the cgmp-bound gaf a domain from the photoreceptor phosphodiesterase 6c |
127
|
326
|
3bjcA |
Crystal structure of the pde5a catalytic domain in complex with a novel inhibitor |
117
|
330
|
3b2rA |
Crystal structure of pde5a1 catalytic domain in complex with vardenafil |
52
|
177
|
2zmfA |
Crystal structure of the c-terminal gaf domain of human phosphodiesterase 10a |
128
|
326
|
2yy2A |
Crystal structure of the human phosphodiesterase 9a catalytic domain complexed with ibmx |
128
|
314
|
2y0jA |
Triazoloquinazolines as a novel class of phosphodiesterase 10a (pde10a) inhibitors, part 2, lead-optimisation. |
31
|
170
|
2xssA |
Crystal structure of gafb from the human phosphodiesterase 5 |
128
|
324
|
2weyA |
Human pde-papaverine complex obtained by ligand soaking of cross- linked protein crystals |
132
|
324
|
2ourA |
Crystal structure of pde10a2 mutant d674a in complex with camp |
137
|
326
|
2ousA |
Crystal structure of pde10a2 mutant d674a |
126
|
304
|
2ovvA |
Crystal structure of the catalytic domain of rat phosphodiesterase 10a |
137
|
329
|
2ouuA |
Crystal structure of pde10a2 mutant d674a in complex with cgmp |
128
|
305
|
2ovyA |
Crystal structure of the catalytic domain of rat phosphodiesterase 10a |
125
|
307
|
2o8hA |
Crystal structure of the catalytic domain of rat phosphodiesterase 10a |
136
|
330
|
2ouyA |
Crystal structure of pde10a2 mutant d564a in complex with camp. |
132
|
326
|
2ouqA |
Crystal structure of pde10a2 in complex with gmp |
12
|
149
|
2k31A |
Solution structure of cgmp-binding gaf domain of phosphodiesterase 5 |
3
|
87
|
2ju4A |
Nmr structure of the gamma subunit of cgmp phosphodiesterase |
132
|
326
|
2hd1A |
Crystal structure of pde9 in complex with ibmx |
130
|
326
|
2h44A |
Crystal structure of pde5a1 in complex with icarisid ii |
131
|
326
|
2h42A |
Crystal structure of pde5 in complex with sildenafil |
122
|
326
|
2h40A |
Crystal structure of the catalytic domain of unliganded pde5 |
133
|
323
|
2chmA |
Crystal structure of n2 substituted pyrazolo pyrimidinones - a flipped binding mode in pde5 |
137
|
326
|
1xozA |
Catalytic domain of human phosphodiesterase 5a in complex with tadalafil |
135
|
326
|
1xp0A |
Catalytic domain of human phosphodiesterase 5a in complex with vardenafil |
124
|
324
|
1uhoA |
Crystal structure of human phosphodiesterase 5 complexed with vardenafil(levitra) |
123
|
324
|
1udtA |
Crystal structure of human phosphodiesterase 5 complexed with sildenafil(viagra) |
101
|
324
|
1uduA |
Crystal structure of human phosphodiesterase 5 complexed with tadalafil(cialis) |
133
|
326
|
1tbfA |
Catalytic domain of human phosphodiesterase 5a in complex with sildenafil |
134
|
326
|
1t9sA |
Catalytic domain of human phosphodiesterase 5a in complex with gmp |
122
|
329
|
1t9rA |
Catalytic domain of human phosphodiesterase 5a |
126
|
326
|
1rkpA |
Crystal structure of pde5a1-ibmx |
5
|
38
|
1fqjC |
Crystal structure of the heterotrimeric complex of the rgs domain of rgs9, the gamma subunit of phosphodiesterase and the gt/i1 chimera alpha subunit [(rgs9)-(pdegamma)-(gt/i1alpha)-(gdp)-(alf4-)-(mg2+)] |