1E41A

Death domain from human fadd/mort1
Total Genus 29
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
29
sequence length
104
structure length
104
Chain Sequence
GSHMGEEDLCAAFNVICDNVGKDWRRLARQLKVSDTKIDSIEDRYPRNLTERVRESLRIWKNTEKENATVAHLVGALRSCQMNLVADLVQEVQQARDLQNRSGA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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molecule tags Apoptosis
molecule keywords FADD PROTEIN
publication title The Three-Dimensional Solution Structure and Dynamic Properties of the Human Fadd Death Domain
pubmed doi rcsb
source organism Homo sapiens
total genus 29
structure length 104
sequence length 104
ec nomenclature
pdb deposition date 2000-06-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00531 Death Death domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.533.10 Mainly Alpha Orthogonal Bundle Death Domain, Fas Death Domain, Fas 1e41A00
1N3KA 4I16A 2N80A 1A1ZA 4DWNA 4M9SA 2GF5A 2DBFA 1WMGA 3YGSP 2MS8A 3LQRA 1E41A 2L9MA 2G7RA 2N97A 2KN6A 3T6PA 4F42A 2P1HA 2YVIA 4D8OA 3KATA 2YGSA 2LWEA 4M9ZA 1UCPA 4P4HI 1DGNA 4RHWA 2LS7A 4P4HA 4IZ7B 2DBDA 2BBRA 2DBHA 4ZBWA 1E3YA 1WXPA 4F44A 3J6JA 2F1SA 1YGOA 4A2QA 1FADA 2NAQA 2DO9A 2OF5A 4O9LA 4A2WA 4UZ0A 1ICHA 2VGQA 1CWWA 4N1KA 2N1FA 4RHWE 2N7ZA 3J63A 4O7QA 2NZ7A 2YU0A 4QOBA 3MOPA 2MS7A 2O71A 2A9IA 2B1WA 3LQQA 1C15A 1D2ZA 4E9MA 1CY5A 2MB9A 2L6AA 2HM2Q 2M5VA 2NSNA 4N1LA 4NQKA 1PN5A 1WH4A 1Z6TA 2OF5H 4FH0A 4IZAB 2MN4A 2N00A 2IB1A 1D2ZB 2YQFA 1DDFA 3EZQA 2N83A 3CL3A 4LWDA 2MPCA 4JQWA 3YGSC 2LWDA 3QF2A 1A1WA 3MOPG 4O6XA 4N1JA 4JUPA 2DBGA 4M9XA 3EZQB 4IZ5E 2A5YB 2D96A 2KM6A 3MOPK 4O9FA 4EWIA 1NGRA 2BBZA 3CRDA
chains in the Genus database with same CATH superfamily
1N3KA 4I16A 2N80A 1A1ZA 4DWNA 4M9SA 2GF5A 2DBFA 1WMGA 3YGSP 2MS8A 3LQRA 1E41A 2MJMA 2L9MA 2G7RA 2N97A 2KN6A 3T6PA 4F42A 2P1HA 2YVIA 4D8OA 3KATA 2YGSA 2LWEA 4M9ZA 1UCPA 4P4HI 1DGNA 4RHWA 2LS7A 4P4HA 4IZ7B 2DBDA 2BBRA 2DBHA 4ZBWA 1E3YA 1WXPA 4F44A 3J6JA 2F1SA 1YGOA 4A2QA 1FADA 2NAQA 2DO9A 2OF5A 4O9LA 4A2WA 4UZ0A 1ICHA 2VGQA 1CWWA 4N1KA 2N1FA 4RHWE 2N7ZA 3J63A 4O7QA 2NZ7A 2YU0A 4QOBA 3MOPA 2MS7A 2O71A 2A9IA 2B1WA 3LQQA 1C15A 2XV9A 1D2ZA 4E9MA 1CY5A 2MB9A 2L6AA 2HM2Q 2M5VA 2NSNA 4N1LA 4NQKA 1PN5A 1WH4A 1Z6TA 2OF5H 4FH0A 4IZAB 2MN4A 2N00A 2IB1A 1D2ZB 2YQFA 1DDFA 3EZQA 2N83A 3CL3A 4LWDA 2MPCA 4JQWA 3YGSC 2LWDA 3QF2A 1A1WA 3MOPG 4O6XA 4N1JA 4JUPA 2DBGA 4M9XA 3EZQB 4IZ5E 2A5YB 2D96A 2KM6A 3MOPK 4O9FA 4EWIA 1NGRA 2BBZA 3CRDA
chains in the Genus database with same CATH topology
1N3KA 4I16A 2N80A 1A1ZA 4DWNA 4M9SA 2GF5A 2DBFA 1WMGA 3YGSP 2MS8A 3LQRA 1E41A 2MJMA 2L9MA 2G7RA 2N97A 2KN6A 3T6PA 4F42A 2P1HA 2YVIA 4D8OA 3KATA 2YGSA 2LWEA 4M9ZA 1UCPA 4P4HI 1DGNA 4RHWA 2LS7A 4P4HA 4IZ7B 2DBDA 2BBRA 2DBHA 4ZBWA 1E3YA 1WXPA 4F44A 3J6JA 2F1SA 1YGOA 4A2QA 1FADA 2NAQA 2DO9A 2OF5A 4O9LA 4A2WA 4UZ0A 1ICHA 2VGQA 1CWWA 4N1KA 2N1FA 4RHWE 2N7ZA 3J63A 4O7QA 2NZ7A 2YU0A 4QOBA 3MOPA 2MS7A 2O71A 2A9IA 2B1WA 3LQQA 1C15A 2XV9A 1D2ZA 4E9MA 1CY5A 2MB9A 2L6AA 2HM2Q 2M5VA 2NSNA 4N1LA 4NQKA 1PN5A 1WH4A 1Z6TA 2OF5H 4FH0A 4IZAB 2MN4A 2N00A 2IB1A 1D2ZB 2YQFA 1DDFA 3EZQA 2N83A 3CL3A 4LWDA 2MPCA 4JQWA 3YGSC 2LWDA 3QF2A 1A1WA 3MOPG 4O6XA 4N1JA 4JUPA 2DBGA 4M9XA 3EZQB 4IZ5E 2A5YB 2D96A 2KM6A 3MOPK 4O9FA 4EWIA 1NGRA 2BBZA 3CRDA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 1N3K A;  4I16 A;  2N80 A;  1A1Z A;  4DWN A;  4M9S A;  2GF5 A;  2DBF A;  1WMG A;  3YGS P;  2MS8 A;  3LQR A;  1E41 A;  2L9M A;  2G7R A;  2N97 A;  2KN6 A;  3T6P A;  4F42 A;  2P1H A;  2YVI A;  4D8O A;  3KAT A;  2YGS A;  2LWE A;  4M9Z A;  1UCP A;  4P4H I;  1DGN A;  4RHW A;  2LS7 A;  4P4H A;  4IZ7 B;  2DBD A;  2BBR A;  2DBH A;  4ZBW A;  1E3Y A;  1WXP A;  4F44 A;  3J6J A;  2F1S A;  1YGO A;  4A2Q A;  1FAD A;  2NAQ A;  2DO9 A;  2OF5 A;  4O9L A;  4A2W A;  4UZ0 A;  1ICH A;  2VGQ A;  1CWW A;  4N1K A;  2N1F A;  4RHW E;  2N7Z A;  3J63 A;  4O7Q A;  2NZ7 A;  2YU0 A;  4QOB A;  3MOP A;  2MS7 A;  2O71 A;  2A9I A;  2B1W A;  3LQQ A;  1C15 A;  1D2Z A;  4E9M A;  1CY5 A;  2MB9 A;  2L6A A;  2HM2 Q;  2M5V A;  2NSN A;  4N1L A;  4NQK A;  1PN5 A;  1WH4 A;  1Z6T A;  2OF5 H;  4FH0 A;  4IZA B;  2MN4 A;  2N00 A;  2IB1 A;  1D2Z B;  2YQF A;  1DDF A;  3EZQ A;  2N83 A;  3CL3 A;  4LWD A;  2MPC A;  4JQW A;  3YGS C;  2LWD A;  3QF2 A;  1A1W A;  3MOP G;  4O6X A;  4N1J A;  4JUP A;  2DBG A;  4M9X A;  3EZQ B;  4IZ5 E;  2A5Y B;  2D96 A;  2KM6 A;  3MOP K;  4O9F A;  4EWI A;  1NGR A;  2BBZ A;  3CRD A; 
#chains in the Genus database with same CATH topology
 1N3K A;  4I16 A;  2N80 A;  1A1Z A;  4DWN A;  4M9S A;  2GF5 A;  2DBF A;  1WMG A;  3YGS P;  2MS8 A;  3LQR A;  1E41 A;  2MJM A;  2L9M A;  2G7R A;  2N97 A;  2KN6 A;  3T6P A;  4F42 A;  2P1H A;  2YVI A;  4D8O A;  3KAT A;  2YGS A;  2LWE A;  4M9Z A;  1UCP A;  4P4H I;  1DGN A;  4RHW A;  2LS7 A;  4P4H A;  4IZ7 B;  2DBD A;  2BBR A;  2DBH A;  4ZBW A;  1E3Y A;  1WXP A;  4F44 A;  3J6J A;  2F1S A;  1YGO A;  4A2Q A;  1FAD A;  2NAQ A;  2DO9 A;  2OF5 A;  4O9L A;  4A2W A;  4UZ0 A;  1ICH A;  2VGQ A;  1CWW A;  4N1K A;  2N1F A;  4RHW E;  2N7Z A;  3J63 A;  4O7Q A;  2NZ7 A;  2YU0 A;  4QOB A;  3MOP A;  2MS7 A;  2O71 A;  2A9I A;  2B1W A;  3LQQ A;  1C15 A;  2XV9 A;  1D2Z A;  4E9M A;  1CY5 A;  2MB9 A;  2L6A A;  2HM2 Q;  2M5V A;  2NSN A;  4N1L A;  4NQK A;  1PN5 A;  1WH4 A;  1Z6T A;  2OF5 H;  4FH0 A;  4IZA B;  2MN4 A;  2N00 A;  2IB1 A;  1D2Z B;  2YQF A;  1DDF A;  3EZQ A;  2N83 A;  3CL3 A;  4LWD A;  2MPC A;  4JQW A;  3YGS C;  2LWD A;  3QF2 A;  1A1W A;  3MOP G;  4O6X A;  4N1J A;  4JUP A;  2DBG A;  4M9X A;  3EZQ B;  4IZ5 E;  2A5Y B;  2D96 A;  2KM6 A;  3MOP K;  4O9F A;  4EWI A;  1NGR A;  2BBZ A;  3CRD A; 
#chains in the Genus database with same CATH homology
 1N3K A;  4I16 A;  2N80 A;  1A1Z A;  4DWN A;  4M9S A;  2GF5 A;  2DBF A;  1WMG A;  3YGS P;  2MS8 A;  3LQR A;  1E41 A;  2MJM A;  2L9M A;  2G7R A;  2N97 A;  2KN6 A;  3T6P A;  4F42 A;  2P1H A;  2YVI A;  4D8O A;  3KAT A;  2YGS A;  2LWE A;  4M9Z A;  1UCP A;  4P4H I;  1DGN A;  4RHW A;  2LS7 A;  4P4H A;  4IZ7 B;  2DBD A;  2BBR A;  2DBH A;  4ZBW A;  1E3Y A;  1WXP A;  4F44 A;  3J6J A;  2F1S A;  1YGO A;  4A2Q A;  1FAD A;  2NAQ A;  2DO9 A;  2OF5 A;  4O9L A;  4A2W A;  4UZ0 A;  1ICH A;  2VGQ A;  1CWW A;  4N1K A;  2N1F A;  4RHW E;  2N7Z A;  3J63 A;  4O7Q A;  2NZ7 A;  2YU0 A;  4QOB A;  3MOP A;  2MS7 A;  2O71 A;  2A9I A;  2B1W A;  3LQQ A;  1C15 A;  2XV9 A;  1D2Z A;  4E9M A;  1CY5 A;  2MB9 A;  2L6A A;  2HM2 Q;  2M5V A;  2NSN A;  4N1L A;  4NQK A;  1PN5 A;  1WH4 A;  1Z6T A;  2OF5 H;  4FH0 A;  4IZA B;  2MN4 A;  2N00 A;  2IB1 A;  1D2Z B;  2YQF A;  1DDF A;  3EZQ A;  2N83 A;  3CL3 A;  4LWD A;  2MPC A;  4JQW A;  3YGS C;  2LWD A;  3QF2 A;  1A1W A;  3MOP G;  4O6X A;  4N1J A;  4JUP A;  2DBG A;  4M9X A;  3EZQ B;  4IZ5 E;  2A5Y B;  2D96 A;  2KM6 A;  3MOP K;  4O9F A;  4EWI A;  1NGR A;  2BBZ A;  3CRD A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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