1EJJA

Crystal structural analysis of phosphoglycerate mutase cocrystallized with 3-phosphoglycerate
Total Genus 196
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
196
Knots found
sequence length
508
structure length
508
Chain Sequence
KKPVALIILDGFALRDETYGNAVAQANKPNFDRYWNEYPHTTLKACGEAVGLPEGQMGNSEVGHLNIGAGRIVYQSLTRINIAIREGEFDRNETFLAAMNHVKQHGTSLHLFGLLSDGGVHSHIHHLYALLRLAAKEGVKRVYIHGFLDGRDVGPQTAPQYIKELQEKIKEYGVGEIATLSGRYYSMDRDKRWDRVEKAYRAMVYGEGPTYRDPLECIEDSYKHGIYDEFVLPSVIVREDGRPVATIQDNDAIIFYNFRPDRAIQISNTFTNEDFREFDRGPKHPKHLFFVCLTHFSETVAGYVAFKPTNLDNTIGEVLSQHGLRQLRIAETEKYPHVTFFMSGGREEEFPGEDRILINSPKVPTYDLKPEMSAYEVTDALLKEIEADKYDAIILNYANPDMVGHSGKLEPTIKAVEAVDECLGKVVDAILAKGGIAIITADHGNADEVLTPDGKPQTAHTTNPVPVIVTKKGIKLRDGGILGDLAPTMLDLLGLPQPKEMTGKSLIV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords PHOSPHOGLYCERATE MUTASE
publication title Structure and mechanism of action of a novel phosphoglycerate mutase from Bacillus stearothermophilus.
pubmed doi rcsb
source organism Geobacillus stearothermophilus
molecule tags Isomerase
total genus 196
structure length 508
sequence length 508
other databases KnotProt 2.0: S +31
ec nomenclature ec 5.4.2.12: Phosphoglycerate mutase (2,3-diphosphoglycerate-independent).
pdb deposition date 2000-03-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01676 Metalloenzyme Metalloenzyme superfamily
A PF06415 iPGM_N BPG-independent PGAM N-terminus (iPGM_N)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 1ejjA02
3.40.1450.10 Alpha Beta 3-Layer(aba) Sandwich 2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain BPG-independent phosphoglycerate mutase, domain B 1ejjA01
4UPIA 5LQQA 4B56A 4NWXA 2GSUA 4LRDA 5INHA 3OT9A 5EGEA 2GA3A 2RH6A 1ANIA 1Y6VA 1P49A 1ED8A 1AJBA 1ELYA 3LXQA 3T00A 2VQRA 3WAXA 1EI6A 3KD8A 5GRRA 1AJDA 3Q3QA 1AJCA 4UPKA 4LRFA 4KAVA 1N2LA 5LRNA 3T01A 2GSOA 4GTXA 3BDFA 1AUKA 4CYSA 4ZG9A 1E2SP 3NKNA 1HDHA 4FDJA 3WAWA 3SZZA 5GOVA 2W8DA 2IUCB 5AJ9A 3NKQA 2W8SA 2W5QA 3BDGB 3UO0A 2GSNA 1KHJA 5L0KA 5DLTA 1E1ZP 5LRMA 1EQJA 3MK0A 4KM4A 2GLQA 4FDIA 4CXKA 3NKMA 4GTYA 1ZEBA 4CYRA 4YR1A 3M7VA 4LR9A 1HJKA 1ANJA 3A52A 3M8ZA 1SHQA 5DLVA 4ZG7A 1EW9A 3CMRA 1ZEFA 5KXAA 3MK1A 5C66A 3ED4A 4LQYA 3IGYB 3M8YA 2W5WA 3MK2A 1KHNA 3E2DA 4N7TA 5DLWA 1O98A 3TG0A 3IDDA 5L0EA 1KH7A 3B5QA 5LIAA 3UN3A 1URAA 1ZEDA 2W5XA 4KJDA 3BDGA 1EW2A 2ANHA 4LR7A 1K7HA 1URBA 5EGHA 3WAYA 4CXUA 1Y7AA 4LRAA 4KAYA 4LR8A 1E33P 4MIVA 1ALHA 3UN5A 3NKOA 1ALJA 1ELXA 3IGZB 1ALKA 1E3CP 4GTWA 4UPLA 3WAVA 2W5VA 1ALIA 4ZGAA 1EW8A 3DYCA 2IFYA 3TX0A 1HQAA 1KHLA 5K4PA 3TWZA 2W5RA 1ELZA 3UNYA 3UN2A 1KH4A 1KH9A 2W5TA 4MHXA 3T02A 4UPHA 2D1GA 2XRGA 1FSUA 3NKPA 3NVLA 4CXSA 2W5SA 1KHKA 4NWJA 2QZUA 4LRBA 4LR2A 1KH5A 2G9YA 2ZKTA 4QAXA 1SHNA 1AJAA 1N2KA 2X98A 3WBHA 1B8JA 5TJ3A 4ZG6A 3SZYA 2XR9A 5HRTA 3NKRA 3BDHA 1O99A 2IUCA 5IJQA 4UOPA 4MY4A 1ED9A 3M8WA 4GTZA 4KJGA 4TN0A 4LRCA 3DPCA 1EJJA 4LREA 5L0BA 4UORA 4UOOA 5IJSA
chains in the Genus database with same CATH superfamily
4UPIA 5LQQA 4B56A 4NWXA 2GSUA 4LRDA 5INHA 3OT9A 5EGEA 2GA3A 2RH6A 1ANIA 1Y6VA 1P49A 1ED8A 1AJBA 1ELYA 3LXQA 3T00A 2VQRA 3WAXA 1EI6A 3KD8A 5GRRA 1AJDA 3Q3QA 1AJCA 4UPKA 4LRFA 4KAVA 1N2LA 5LRNA 3T01A 2GSOA 4GTXA 3BDFA 1AUKA 4CYSA 4ZG9A 1E2SP 3NKNA 1HDHA 4FDJA 3WAWA 3SZZA 5GOVA 2W8DA 2IUCB 5AJ9A 3NKQA 2W8SA 2W5QA 3BDGB 3UO0A 2GSNA 1KHJA 5L0KA 5DLTA 1E1ZP 5LRMA 1EQJA 3MK0A 4KM4A 2GLQA 4FDIA 4CXKA 3NKMA 4GTYA 1ZEBA 4CYRA 4YR1A 3M7VA 4LR9A 1HJKA 1ANJA 3A52A 3M8ZA 1SHQA 5DLVA 4ZG7A 1EW9A 3CMRA 1ZEFA 5KXAA 3MK1A 5C66A 3ED4A 4LQYA 3IGYB 3M8YA 2W5WA 3MK2A 1KHNA 3E2DA 4N7TA 5DLWA 1O98A 3TG0A 3IDDA 5L0EA 1KH7A 3B5QA 5LIAA 3UN3A 1URAA 1ZEDA 2W5XA 4KJDA 3BDGA 1EW2A 2ANHA 4LR7A 1K7HA 1URBA 5EGHA 3WAYA 4CXUA 1Y7AA 4LRAA 4KAYA 4LR8A 1E33P 4MIVA 1ALHA 3UN5A 3NKOA 1ALJA 1ELXA 3IGZB 1ALKA 1E3CP 4GTWA 4UPLA 3WAVA 2W5VA 1ALIA 4ZGAA 1EW8A 3DYCA 2IFYA 3TX0A 1HQAA 1KHLA 5K4PA 3TWZA 2W5RA 1ELZA 3UNYA 3UN2A 1KH4A 1KH9A 2W5TA 4MHXA 3T02A 4UPHA 2D1GA 2XRGA 1FSUA 3NKPA 3NVLA 4CXSA 2W5SA 1KHKA 4NWJA 2QZUA 4LRBA 4LR2A 1KH5A 2G9YA 2ZKTA 4QAXA 1SHNA 1AJAA 1N2KA 2X98A 3WBHA 1B8JA 5TJ3A 4ZG6A 3SZYA 2XR9A 5HRTA 3NKRA 3BDHA 1O99A 2IUCA 5IJQA 4UOPA 4MY4A 1ED9A 3M8WA 4GTZA 4KJGA 4TN0A 4LRCA 3DPCA 1EJJA 4LREA 5L0BA 4UORA 4UOOA 5IJSA
chains in the Genus database with same CATH topology
4UPIA 5LQQA 4B56A 4NWXA 2GSUA 4LRDA 5INHA 3OT9A 5EGEA 2GA3A 2RH6A 1ANIA 1Y6VA 1P49A 1ED8A 1AJBA 1ELYA 3LXQA 3T00A 2VQRA 3WAXA 1EI6A 3KD8A 5GRRA 1AJDA 3Q3QA 1AJCA 4UPKA 4LRFA 4KAVA 1N2LA 5LRNA 3T01A 2GSOA 4GTXA 3BDFA 1AUKA 4CYSA 4ZG9A 1E2SP 3NKNA 1HDHA 4FDJA 3WAWA 3SZZA 5GOVA 2W8DA 2IUCB 5AJ9A 3NKQA 2W8SA 2W5QA 3BDGB 3UO0A 2GSNA 1KHJA 5L0KA 5DLTA 1E1ZP 5LRMA 1EQJA 3MK0A 4KM4A 2GLQA 4FDIA 4CXKA 3NKMA 4GTYA 1ZEBA 4CYRA 4YR1A 3M7VA 4LR9A 1HJKA 1ANJA 3A52A 3M8ZA 1SHQA 5DLVA 4ZG7A 1EW9A 3CMRA 1ZEFA 5KXAA 3MK1A 5C66A 3ED4A 4LQYA 3IGYB 3M8YA 2W5WA 3MK2A 1KHNA 3E2DA 4N7TA 5DLWA 1O98A 3TG0A 3IDDA 5L0EA 1KH7A 3B5QA 5LIAA 3UN3A 1URAA 1ZEDA 2W5XA 4KJDA 3BDGA 1EW2A 2ANHA 4LR7A 1K7HA 1URBA 5EGHA 3WAYA 4CXUA 1Y7AA 4LRAA 4KAYA 4LR8A 1E33P 4MIVA 1ALHA 3UN5A 3NKOA 1ALJA 1ELXA 3IGZB 1ALKA 1E3CP 4GTWA 4UPLA 3WAVA 2W5VA 1ALIA 4ZGAA 1EW8A 3DYCA 2IFYA 3TX0A 1HQAA 1KHLA 5K4PA 3TWZA 2W5RA 1ELZA 3UNYA 3UN2A 1KH4A 1KH9A 2W5TA 4MHXA 3T02A 4UPHA 2D1GA 2XRGA 1FSUA 3NKPA 3NVLA 4CXSA 2W5SA 1KHKA 4NWJA 2QZUA 4LRBA 4LR2A 1KH5A 2G9YA 2ZKTA 4QAXA 1SHNA 1AJAA 1N2KA 2X98A 3WBHA 1B8JA 5TJ3A 4ZG6A 3SZYA 2XR9A 5HRTA 3NKRA 3BDHA 1O99A 2IUCA 5IJQA 4UOPA 4MY4A 1ED9A 3M8WA 4GTZA 4KJGA 4TN0A 4LRCA 3DPCA 1EJJA 4LREA 5L0BA 4UORA 4UOOA 5IJSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4UPI A;  5LQQ A;  4B56 A;  4NWX A;  2GSU A;  4LRD A;  5INH A;  3OT9 A;  5EGE A;  2GA3 A;  2RH6 A;  1ANI A;  1Y6V A;  1P49 A;  1ED8 A;  1AJB A;  1ELY A;  3LXQ A;  3T00 A;  2VQR A;  3WAX A;  1EI6 A;  3KD8 A;  5GRR A;  1AJD A;  3Q3Q A;  1AJC A;  4UPK A;  4LRF A;  4KAV A;  1N2L A;  5LRN A;  3T01 A;  2GSO A;  4GTX A;  3BDF A;  1AUK A;  4CYS A;  4ZG9 A;  1E2S P;  3NKN A;  1HDH A;  4FDJ A;  3WAW A;  3SZZ A;  5GOV A;  2W8D A;  2IUC B;  5AJ9 A;  3NKQ A;  2W8S A;  2W5Q A;  3BDG B;  3UO0 A;  2GSN A;  1KHJ A;  5L0K A;  5DLT A;  1E1Z P;  5LRM A;  1EQJ A;  3MK0 A;  4KM4 A;  2GLQ A;  4FDI A;  4CXK A;  3NKM A;  4GTY A;  1ZEB A;  4CYR A;  4YR1 A;  3M7V A;  4LR9 A;  1HJK A;  1ANJ A;  3A52 A;  3M8Z A;  1SHQ A;  5DLV A;  4ZG7 A;  1EW9 A;  3CMR A;  1ZEF A;  5KXA A;  3MK1 A;  5C66 A;  3ED4 A;  4LQY A;  3IGY B;  3M8Y A;  2W5W A;  3MK2 A;  1KHN A;  3E2D A;  4N7T A;  5DLW A;  1O98 A;  3TG0 A;  3IDD A;  5L0E A;  1KH7 A;  3B5Q A;  5LIA A;  3UN3 A;  1URA A;  1ZED A;  2W5X A;  4KJD A;  3BDG A;  1EW2 A;  2ANH A;  4LR7 A;  1K7H A;  1URB A;  5EGH A;  3WAY A;  4CXU A;  1Y7A A;  4LRA A;  4KAY A;  4LR8 A;  1E33 P;  4MIV A;  1ALH A;  3UN5 A;  3NKO A;  1ALJ A;  1ELX A;  3IGZ B;  1ALK A;  1E3C P;  4GTW A;  4UPL A;  3WAV A;  2W5V A;  1ALI A;  4ZGA A;  1EW8 A;  3DYC A;  2IFY A;  3TX0 A;  1HQA A;  1KHL A;  5K4P A;  3TWZ A;  2W5R A;  1ELZ A;  3UNY A;  3UN2 A;  1KH4 A;  1KH9 A;  2W5T A;  4MHX A;  3T02 A;  4UPH A;  2D1G A;  2XRG A;  1FSU A;  3NKP A;  3NVL A;  4CXS A;  2W5S A;  1KHK A;  4NWJ A;  2QZU A;  4LRB A;  4LR2 A;  1KH5 A;  2G9Y A;  2ZKT A;  4QAX A;  1SHN A;  1AJA A;  1N2K A;  2X98 A;  3WBH A;  1B8J A;  5TJ3 A;  4ZG6 A;  3SZY A;  2XR9 A;  5HRT A;  3NKR A;  3BDH A;  1O99 A;  2IUC A;  5IJQ A;  4UOP A;  4MY4 A;  1ED9 A;  3M8W A;  4GTZ A;  4KJG A;  4TN0 A;  4LRC A;  3DPC A;  1EJJ A;  4LRE A;  5L0B A;  4UOR A;  4UOO A;  5IJS A; 
#chains in the Genus database with same CATH topology
 4UPI A;  5LQQ A;  4B56 A;  4NWX A;  2GSU A;  4LRD A;  5INH A;  3OT9 A;  5EGE A;  2GA3 A;  2RH6 A;  1ANI A;  1Y6V A;  1P49 A;  1ED8 A;  1AJB A;  1ELY A;  3LXQ A;  3T00 A;  2VQR A;  3WAX A;  1EI6 A;  3KD8 A;  5GRR A;  1AJD A;  3Q3Q A;  1AJC A;  4UPK A;  4LRF A;  4KAV A;  1N2L A;  5LRN A;  3T01 A;  2GSO A;  4GTX A;  3BDF A;  1AUK A;  4CYS A;  4ZG9 A;  1E2S P;  3NKN A;  1HDH A;  4FDJ A;  3WAW A;  3SZZ A;  5GOV A;  2W8D A;  2IUC B;  5AJ9 A;  3NKQ A;  2W8S A;  2W5Q A;  3BDG B;  3UO0 A;  2GSN A;  1KHJ A;  5L0K A;  5DLT A;  1E1Z P;  5LRM A;  1EQJ A;  3MK0 A;  4KM4 A;  2GLQ A;  4FDI A;  4CXK A;  3NKM A;  4GTY A;  1ZEB A;  4CYR A;  4YR1 A;  3M7V A;  4LR9 A;  1HJK A;  1ANJ A;  3A52 A;  3M8Z A;  1SHQ A;  5DLV A;  4ZG7 A;  1EW9 A;  3CMR A;  1ZEF A;  5KXA A;  3MK1 A;  5C66 A;  3ED4 A;  4LQY A;  3IGY B;  3M8Y A;  2W5W A;  3MK2 A;  1KHN A;  3E2D A;  4N7T A;  5DLW A;  1O98 A;  3TG0 A;  3IDD A;  5L0E A;  1KH7 A;  3B5Q A;  5LIA A;  3UN3 A;  1URA A;  1ZED A;  2W5X A;  4KJD A;  3BDG A;  1EW2 A;  2ANH A;  4LR7 A;  1K7H A;  1URB A;  5EGH A;  3WAY A;  4CXU A;  1Y7A A;  4LRA A;  4KAY A;  4LR8 A;  1E33 P;  4MIV A;  1ALH A;  3UN5 A;  3NKO A;  1ALJ A;  1ELX A;  3IGZ B;  1ALK A;  1E3C P;  4GTW A;  4UPL A;  3WAV A;  2W5V A;  1ALI A;  4ZGA A;  1EW8 A;  3DYC A;  2IFY A;  3TX0 A;  1HQA A;  1KHL A;  5K4P A;  3TWZ A;  2W5R A;  1ELZ A;  3UNY A;  3UN2 A;  1KH4 A;  1KH9 A;  2W5T A;  4MHX A;  3T02 A;  4UPH A;  2D1G A;  2XRG A;  1FSU A;  3NKP A;  3NVL A;  4CXS A;  2W5S A;  1KHK A;  4NWJ A;  2QZU A;  4LRB A;  4LR2 A;  1KH5 A;  2G9Y A;  2ZKT A;  4QAX A;  1SHN A;  1AJA A;  1N2K A;  2X98 A;  3WBH A;  1B8J A;  5TJ3 A;  4ZG6 A;  3SZY A;  2XR9 A;  5HRT A;  3NKR A;  3BDH A;  1O99 A;  2IUC A;  5IJQ A;  4UOP A;  4MY4 A;  1ED9 A;  3M8W A;  4GTZ A;  4KJG A;  4TN0 A;  4LRC A;  3DPC A;  1EJJ A;  4LRE A;  5L0B A;  4UOR A;  4UOO A;  5IJS A; 
#chains in the Genus database with same CATH homology
 4UPI A;  5LQQ A;  4B56 A;  4NWX A;  2GSU A;  4LRD A;  5INH A;  3OT9 A;  5EGE A;  2GA3 A;  2RH6 A;  1ANI A;  1Y6V A;  1P49 A;  1ED8 A;  1AJB A;  1ELY A;  3LXQ A;  3T00 A;  2VQR A;  3WAX A;  1EI6 A;  3KD8 A;  5GRR A;  1AJD A;  3Q3Q A;  1AJC A;  4UPK A;  4LRF A;  4KAV A;  1N2L A;  5LRN A;  3T01 A;  2GSO A;  4GTX A;  3BDF A;  1AUK A;  4CYS A;  4ZG9 A;  1E2S P;  3NKN A;  1HDH A;  4FDJ A;  3WAW A;  3SZZ A;  5GOV A;  2W8D A;  2IUC B;  5AJ9 A;  3NKQ A;  2W8S A;  2W5Q A;  3BDG B;  3UO0 A;  2GSN A;  1KHJ A;  5L0K A;  5DLT A;  1E1Z P;  5LRM A;  1EQJ A;  3MK0 A;  4KM4 A;  2GLQ A;  4FDI A;  4CXK A;  3NKM A;  4GTY A;  1ZEB A;  4CYR A;  4YR1 A;  3M7V A;  4LR9 A;  1HJK A;  1ANJ A;  3A52 A;  3M8Z A;  1SHQ A;  5DLV A;  4ZG7 A;  1EW9 A;  3CMR A;  1ZEF A;  5KXA A;  3MK1 A;  5C66 A;  3ED4 A;  4LQY A;  3IGY B;  3M8Y A;  2W5W A;  3MK2 A;  1KHN A;  3E2D A;  4N7T A;  5DLW A;  1O98 A;  3TG0 A;  3IDD A;  5L0E A;  1KH7 A;  3B5Q A;  5LIA A;  3UN3 A;  1URA A;  1ZED A;  2W5X A;  4KJD A;  3BDG A;  1EW2 A;  2ANH A;  4LR7 A;  1K7H A;  1URB A;  5EGH A;  3WAY A;  4CXU A;  1Y7A A;  4LRA A;  4KAY A;  4LR8 A;  1E33 P;  4MIV A;  1ALH A;  3UN5 A;  3NKO A;  1ALJ A;  1ELX A;  3IGZ B;  1ALK A;  1E3C P;  4GTW A;  4UPL A;  3WAV A;  2W5V A;  1ALI A;  4ZGA A;  1EW8 A;  3DYC A;  2IFY A;  3TX0 A;  1HQA A;  1KHL A;  5K4P A;  3TWZ A;  2W5R A;  1ELZ A;  3UNY A;  3UN2 A;  1KH4 A;  1KH9 A;  2W5T A;  4MHX A;  3T02 A;  4UPH A;  2D1G A;  2XRG A;  1FSU A;  3NKP A;  3NVL A;  4CXS A;  2W5S A;  1KHK A;  4NWJ A;  2QZU A;  4LRB A;  4LR2 A;  1KH5 A;  2G9Y A;  2ZKT A;  4QAX A;  1SHN A;  1AJA A;  1N2K A;  2X98 A;  3WBH A;  1B8J A;  5TJ3 A;  4ZG6 A;  3SZY A;  2XR9 A;  5HRT A;  3NKR A;  3BDH A;  1O99 A;  2IUC A;  5IJQ A;  4UOP A;  4MY4 A;  1ED9 A;  3M8W A;  4GTZ A;  4KJG A;  4TN0 A;  4LRC A;  3DPC A;  1EJJ A;  4LRE A;  5L0B A;  4UOR A;  4UOO A;  5IJS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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