1ELYA

E. coli alkaline phosphatase mutant (s102c)
Total Genus 157
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
157
Knots found
sequence length
449
structure length
449
Chain Sequence
TPEMPVLENRAAQGDITAPGGARRLTGDQTAALRDSLSDKPAKNIILLIGDGMGDSEITAARNYAEGAGGFFKGIDALPLTGQYTHYALNKKTGKPDYVTDCAASATAWSTGVKTYNGALGVDIHEKDHPTILEMAKAAGLATGNVSTAELQDATPAALVAHVTSRKCYGPSATSEKCPGNALEKGGKGSITEQLLNARADVTLGGGAKTFAETATAGEWQGKTLREQAQARGYQLVSDAASLNSVTEANQQKPLLGLFADGNMPVRWLGPKATYHGNIDKPAVTCTPNPQRNDSVPTLAQMTDKAIELLSKNEKGFFLQVEGASIDKQDHAANPCGQIGETVDLDEAVQRALEFAKKEGNTLVIVTADHAHASQIVAPDTKAPGLTQALNTKDGAVMVMSYGNSEEDSQEHTGSQLRIAAYGPHAANVVGLTDQTDLFYTMKAALGLK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords ALKALINE PHOSPHATASE
publication title Kinetic and X-ray structural studies of three mutant E. coli alkaline phosphatases: insights into the catalytic mechanism without the nucleophile Ser102.
pubmed doi rcsb
source organism Escherichia coli
molecule tags Hydrolase
total genus 157
structure length 449
sequence length 449
chains with identical sequence B
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.1.3.1: Alkaline phosphatase.
pdb deposition date 1998-02-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00245 Alk_phosphatase Alkaline phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 1elyA00
3UO0A 3NKQA 1KH9A 2W5RA 4FDIA 1AJCA 4GTXA 5IJSA 3TG0A 4UORA 4NWJA 5DLWA 5LQQA 4CXSA 3NVLA 3Q3QA 1ALKA 1KHKA 3A52A 1P49A 4LREA 1O99A 4LQYA 5GOVA 3DPCA 1KH4A 3MK2A 2ZKTA 4GTZA 3UN3A 4N7TA 1ANIA 1AJAA 4KJGA 3DYCA 4MHXA 3B5QA 3BDFA 4GTWA 1N2KA 1SHNA 3WAXA 5L0KA 5C66A 2IFYA 1URAA 2W5WA 3CMRA 1O98A 3M7VA 4GTYA 3ED4A 3BDGB 2QZUA 2IUCA 4CXUA 5DLTA 2XR9A 1ELXA 3WBHA 5L0BA 1ALIA 1HQAA 1K7HA 1EW8A 2W5XA 4LRBA 4MIVA 3M8ZA 5K4PA 4LRCA 1N2LA 1ALJA 3TWZA 2GA3A 4ZG6A 5LIAA 5EGEA 4CYSA 1AUKA 3MK0A 3TX0A 5GRRA 1E33P 4LRFA 5HRTA 3WAYA 1AJBA 4UPIA 4YR1A 1ALHA 1SHQA 2W5QA 1HDHA 5AJ9A 3NKNA 1KHJA 1Y6VA 4CYRA 4ZG7A 3NKRA 1B8JA 1ED9A 3T00A 3NKMA 1EW2A 4LRAA 5L0EA 3IGYB 4ZG9A 3T01A 2G9YA 2GSNA 3IDDA 4UOOA 1URBA 4ZGAA 1E1ZP 4KJDA 2X98A 2W5VA 3UNYA 2GSOA 1EQJA 3IGZB 5IJQA 5KXAA 1EW9A 1KHLA 1KH7A 1Y7AA 1AJDA 4KAVA 5EGHA 3MK1A 4UPKA 5TJ3A 1ZEFA 1E2SP 5DLVA 3BDHA 3UN5A 2W5SA 3OT9A 1EI6A 4LRDA 4FDJA 4KM4A 4LR9A 1ANJA 3UN2A 4NWXA 1ZEBA 2W8DA 1E3CP 1FSUA 4CXKA 2IUCB 1ED8A 4UOPA 2RH6A 2GLQA 1ZEDA 4KAYA 4MY4A 4UPHA 4UPLA 1HJKA 2W5TA 1ELZA 3T02A 1EJJA 4LR7A 3SZZA 2VQRA 2W8SA 4QAXA 3SZYA 3WAWA 1KH5A 5LRMA 3BDGA 3NKOA 3NKPA 4LR2A 3M8WA 2GSUA 2D1GA 3E2DA 1KHNA 3KD8A 2XRGA 2ANHA 3M8YA 4LR8A 4TN0A 3WAVA 1ELYA 5INHA 5LRNA 3LXQA 4B56A
chains in the Genus database with same CATH superfamily
3UO0A 3NKQA 1KH9A 2W5RA 4FDIA 1AJCA 4GTXA 5IJSA 3TG0A 4UORA 4NWJA 5DLWA 5LQQA 4CXSA 3NVLA 3Q3QA 1ALKA 1KHKA 3A52A 1P49A 4LREA 1O99A 4LQYA 5GOVA 3DPCA 1KH4A 3MK2A 2ZKTA 4GTZA 3UN3A 4N7TA 1ANIA 1AJAA 4KJGA 3DYCA 4MHXA 3B5QA 3BDFA 4GTWA 1N2KA 1SHNA 3WAXA 5L0KA 5C66A 2IFYA 1URAA 2W5WA 3CMRA 1O98A 3M7VA 4GTYA 3ED4A 3BDGB 2QZUA 2IUCA 4CXUA 5DLTA 2XR9A 1ELXA 3WBHA 5L0BA 1ALIA 1HQAA 1K7HA 1EW8A 2W5XA 4LRBA 4MIVA 3M8ZA 5K4PA 4LRCA 1N2LA 1ALJA 3TWZA 2GA3A 4ZG6A 5LIAA 5EGEA 4CYSA 1AUKA 3MK0A 3TX0A 5GRRA 1E33P 4LRFA 5HRTA 3WAYA 1AJBA 4UPIA 4YR1A 1ALHA 1SHQA 2W5QA 1HDHA 5AJ9A 3NKNA 1KHJA 1Y6VA 4CYRA 4ZG7A 3NKRA 1B8JA 1ED9A 3T00A 3NKMA 1EW2A 4LRAA 5L0EA 3IGYB 4ZG9A 3T01A 2G9YA 2GSNA 3IDDA 4UOOA 1URBA 4ZGAA 1E1ZP 4KJDA 2X98A 2W5VA 3UNYA 2GSOA 1EQJA 3IGZB 5IJQA 5KXAA 1EW9A 1KHLA 1KH7A 1Y7AA 1AJDA 4KAVA 5EGHA 3MK1A 4UPKA 5TJ3A 1ZEFA 1E2SP 5DLVA 3BDHA 3UN5A 2W5SA 3OT9A 1EI6A 4LRDA 4FDJA 4KM4A 4LR9A 1ANJA 3UN2A 4NWXA 1ZEBA 2W8DA 1E3CP 1FSUA 4CXKA 2IUCB 1ED8A 4UOPA 2RH6A 2GLQA 1ZEDA 4KAYA 4MY4A 4UPHA 4UPLA 1HJKA 2W5TA 1ELZA 3T02A 1EJJA 4LR7A 3SZZA 2VQRA 2W8SA 4QAXA 3SZYA 3WAWA 1KH5A 5LRMA 3BDGA 3NKOA 3NKPA 4LR2A 3M8WA 2GSUA 2D1GA 3E2DA 1KHNA 3KD8A 2XRGA 2ANHA 3M8YA 4LR8A 4TN0A 3WAVA 1ELYA 5INHA 5LRNA 3LXQA 4B56A
chains in the Genus database with same CATH topology
3UO0A 3NKQA 1KH9A 2W5RA 4FDIA 1AJCA 4GTXA 5IJSA 3TG0A 4UORA 4NWJA 5DLWA 5LQQA 4CXSA 3NVLA 3Q3QA 1ALKA 1KHKA 3A52A 1P49A 4LREA 1O99A 4LQYA 5GOVA 3DPCA 1KH4A 3MK2A 2ZKTA 4GTZA 3UN3A 4N7TA 1ANIA 1AJAA 4KJGA 3DYCA 4MHXA 3B5QA 3BDFA 4GTWA 1N2KA 1SHNA 3WAXA 5L0KA 5C66A 2IFYA 1URAA 2W5WA 3CMRA 1O98A 3M7VA 4GTYA 3ED4A 3BDGB 2QZUA 2IUCA 4CXUA 5DLTA 2XR9A 1ELXA 3WBHA 5L0BA 1ALIA 1HQAA 1K7HA 1EW8A 2W5XA 4LRBA 4MIVA 3M8ZA 5K4PA 4LRCA 1N2LA 1ALJA 3TWZA 2GA3A 4ZG6A 5LIAA 5EGEA 4CYSA 1AUKA 3MK0A 3TX0A 5GRRA 1E33P 4LRFA 5HRTA 3WAYA 1AJBA 4UPIA 4YR1A 1ALHA 1SHQA 2W5QA 1HDHA 5AJ9A 3NKNA 1KHJA 1Y6VA 4CYRA 4ZG7A 3NKRA 1B8JA 1ED9A 3T00A 3NKMA 1EW2A 4LRAA 5L0EA 3IGYB 4ZG9A 3T01A 2G9YA 2GSNA 3IDDA 4UOOA 1URBA 4ZGAA 1E1ZP 4KJDA 2X98A 2W5VA 3UNYA 2GSOA 1EQJA 3IGZB 5IJQA 5KXAA 1EW9A 1KHLA 1KH7A 1Y7AA 1AJDA 4KAVA 5EGHA 3MK1A 4UPKA 5TJ3A 1ZEFA 1E2SP 5DLVA 3BDHA 3UN5A 2W5SA 3OT9A 1EI6A 4LRDA 4FDJA 4KM4A 4LR9A 1ANJA 3UN2A 4NWXA 1ZEBA 2W8DA 1E3CP 1FSUA 4CXKA 2IUCB 1ED8A 4UOPA 2RH6A 2GLQA 1ZEDA 4KAYA 4MY4A 4UPHA 4UPLA 1HJKA 2W5TA 1ELZA 3T02A 1EJJA 4LR7A 3SZZA 2VQRA 2W8SA 4QAXA 3SZYA 3WAWA 1KH5A 5LRMA 3BDGA 3NKOA 3NKPA 4LR2A 3M8WA 2GSUA 2D1GA 3E2DA 1KHNA 3KD8A 2XRGA 2ANHA 3M8YA 4LR8A 4TN0A 3WAVA 1ELYA 5INHA 5LRNA 3LXQA 4B56A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3UO0 A;  3NKQ A;  1KH9 A;  2W5R A;  4FDI A;  1AJC A;  4GTX A;  5IJS A;  3TG0 A;  4UOR A;  4NWJ A;  5DLW A;  5LQQ A;  4CXS A;  3NVL A;  3Q3Q A;  1ALK A;  1KHK A;  3A52 A;  1P49 A;  4LRE A;  1O99 A;  4LQY A;  5GOV A;  3DPC A;  1KH4 A;  3MK2 A;  2ZKT A;  4GTZ A;  3UN3 A;  4N7T A;  1ANI A;  1AJA A;  4KJG A;  3DYC A;  4MHX A;  3B5Q A;  3BDF A;  4GTW A;  1N2K A;  1SHN A;  3WAX A;  5L0K A;  5C66 A;  2IFY A;  1URA A;  2W5W A;  3CMR A;  1O98 A;  3M7V A;  4GTY A;  3ED4 A;  3BDG B;  2QZU A;  2IUC A;  4CXU A;  5DLT A;  2XR9 A;  1ELX A;  3WBH A;  5L0B A;  1ALI A;  1HQA A;  1K7H A;  1EW8 A;  2W5X A;  4LRB A;  4MIV A;  3M8Z A;  5K4P A;  4LRC A;  1N2L A;  1ALJ A;  3TWZ A;  2GA3 A;  4ZG6 A;  5LIA A;  5EGE A;  4CYS A;  1AUK A;  3MK0 A;  3TX0 A;  5GRR A;  1E33 P;  4LRF A;  5HRT A;  3WAY A;  1AJB A;  4UPI A;  4YR1 A;  1ALH A;  1SHQ A;  2W5Q A;  1HDH A;  5AJ9 A;  3NKN A;  1KHJ A;  1Y6V A;  4CYR A;  4ZG7 A;  3NKR A;  1B8J A;  1ED9 A;  3T00 A;  3NKM A;  1EW2 A;  4LRA A;  5L0E A;  3IGY B;  4ZG9 A;  3T01 A;  2G9Y A;  2GSN A;  3IDD A;  4UOO A;  1URB A;  4ZGA A;  1E1Z P;  4KJD A;  2X98 A;  2W5V A;  3UNY A;  2GSO A;  1EQJ A;  3IGZ B;  5IJQ A;  5KXA A;  1EW9 A;  1KHL A;  1KH7 A;  1Y7A A;  1AJD A;  4KAV A;  5EGH A;  3MK1 A;  4UPK A;  5TJ3 A;  1ZEF A;  1E2S P;  5DLV A;  3BDH A;  3UN5 A;  2W5S A;  3OT9 A;  1EI6 A;  4LRD A;  4FDJ A;  4KM4 A;  4LR9 A;  1ANJ A;  3UN2 A;  4NWX A;  1ZEB A;  2W8D A;  1E3C P;  1FSU A;  4CXK A;  2IUC B;  1ED8 A;  4UOP A;  2RH6 A;  2GLQ A;  1ZED A;  4KAY A;  4MY4 A;  4UPH A;  4UPL A;  1HJK A;  2W5T A;  1ELZ A;  3T02 A;  1EJJ A;  4LR7 A;  3SZZ A;  2VQR A;  2W8S A;  4QAX A;  3SZY A;  3WAW A;  1KH5 A;  5LRM A;  3BDG A;  3NKO A;  3NKP A;  4LR2 A;  3M8W A;  2GSU A;  2D1G A;  3E2D A;  1KHN A;  3KD8 A;  2XRG A;  2ANH A;  3M8Y A;  4LR8 A;  4TN0 A;  3WAV A;  1ELY A;  5INH A;  5LRN A;  3LXQ A;  4B56 A; 
#chains in the Genus database with same CATH topology
 3UO0 A;  3NKQ A;  1KH9 A;  2W5R A;  4FDI A;  1AJC A;  4GTX A;  5IJS A;  3TG0 A;  4UOR A;  4NWJ A;  5DLW A;  5LQQ A;  4CXS A;  3NVL A;  3Q3Q A;  1ALK A;  1KHK A;  3A52 A;  1P49 A;  4LRE A;  1O99 A;  4LQY A;  5GOV A;  3DPC A;  1KH4 A;  3MK2 A;  2ZKT A;  4GTZ A;  3UN3 A;  4N7T A;  1ANI A;  1AJA A;  4KJG A;  3DYC A;  4MHX A;  3B5Q A;  3BDF A;  4GTW A;  1N2K A;  1SHN A;  3WAX A;  5L0K A;  5C66 A;  2IFY A;  1URA A;  2W5W A;  3CMR A;  1O98 A;  3M7V A;  4GTY A;  3ED4 A;  3BDG B;  2QZU A;  2IUC A;  4CXU A;  5DLT A;  2XR9 A;  1ELX A;  3WBH A;  5L0B A;  1ALI A;  1HQA A;  1K7H A;  1EW8 A;  2W5X A;  4LRB A;  4MIV A;  3M8Z A;  5K4P A;  4LRC A;  1N2L A;  1ALJ A;  3TWZ A;  2GA3 A;  4ZG6 A;  5LIA A;  5EGE A;  4CYS A;  1AUK A;  3MK0 A;  3TX0 A;  5GRR A;  1E33 P;  4LRF A;  5HRT A;  3WAY A;  1AJB A;  4UPI A;  4YR1 A;  1ALH A;  1SHQ A;  2W5Q A;  1HDH A;  5AJ9 A;  3NKN A;  1KHJ A;  1Y6V A;  4CYR A;  4ZG7 A;  3NKR A;  1B8J A;  1ED9 A;  3T00 A;  3NKM A;  1EW2 A;  4LRA A;  5L0E A;  3IGY B;  4ZG9 A;  3T01 A;  2G9Y A;  2GSN A;  3IDD A;  4UOO A;  1URB A;  4ZGA A;  1E1Z P;  4KJD A;  2X98 A;  2W5V A;  3UNY A;  2GSO A;  1EQJ A;  3IGZ B;  5IJQ A;  5KXA A;  1EW9 A;  1KHL A;  1KH7 A;  1Y7A A;  1AJD A;  4KAV A;  5EGH A;  3MK1 A;  4UPK A;  5TJ3 A;  1ZEF A;  1E2S P;  5DLV A;  3BDH A;  3UN5 A;  2W5S A;  3OT9 A;  1EI6 A;  4LRD A;  4FDJ A;  4KM4 A;  4LR9 A;  1ANJ A;  3UN2 A;  4NWX A;  1ZEB A;  2W8D A;  1E3C P;  1FSU A;  4CXK A;  2IUC B;  1ED8 A;  4UOP A;  2RH6 A;  2GLQ A;  1ZED A;  4KAY A;  4MY4 A;  4UPH A;  4UPL A;  1HJK A;  2W5T A;  1ELZ A;  3T02 A;  1EJJ A;  4LR7 A;  3SZZ A;  2VQR A;  2W8S A;  4QAX A;  3SZY A;  3WAW A;  1KH5 A;  5LRM A;  3BDG A;  3NKO A;  3NKP A;  4LR2 A;  3M8W A;  2GSU A;  2D1G A;  3E2D A;  1KHN A;  3KD8 A;  2XRG A;  2ANH A;  3M8Y A;  4LR8 A;  4TN0 A;  3WAV A;  1ELY A;  5INH A;  5LRN A;  3LXQ A;  4B56 A; 
#chains in the Genus database with same CATH homology
 3UO0 A;  3NKQ A;  1KH9 A;  2W5R A;  4FDI A;  1AJC A;  4GTX A;  5IJS A;  3TG0 A;  4UOR A;  4NWJ A;  5DLW A;  5LQQ A;  4CXS A;  3NVL A;  3Q3Q A;  1ALK A;  1KHK A;  3A52 A;  1P49 A;  4LRE A;  1O99 A;  4LQY A;  5GOV A;  3DPC A;  1KH4 A;  3MK2 A;  2ZKT A;  4GTZ A;  3UN3 A;  4N7T A;  1ANI A;  1AJA A;  4KJG A;  3DYC A;  4MHX A;  3B5Q A;  3BDF A;  4GTW A;  1N2K A;  1SHN A;  3WAX A;  5L0K A;  5C66 A;  2IFY A;  1URA A;  2W5W A;  3CMR A;  1O98 A;  3M7V A;  4GTY A;  3ED4 A;  3BDG B;  2QZU A;  2IUC A;  4CXU A;  5DLT A;  2XR9 A;  1ELX A;  3WBH A;  5L0B A;  1ALI A;  1HQA A;  1K7H A;  1EW8 A;  2W5X A;  4LRB A;  4MIV A;  3M8Z A;  5K4P A;  4LRC A;  1N2L A;  1ALJ A;  3TWZ A;  2GA3 A;  4ZG6 A;  5LIA A;  5EGE A;  4CYS A;  1AUK A;  3MK0 A;  3TX0 A;  5GRR A;  1E33 P;  4LRF A;  5HRT A;  3WAY A;  1AJB A;  4UPI A;  4YR1 A;  1ALH A;  1SHQ A;  2W5Q A;  1HDH A;  5AJ9 A;  3NKN A;  1KHJ A;  1Y6V A;  4CYR A;  4ZG7 A;  3NKR A;  1B8J A;  1ED9 A;  3T00 A;  3NKM A;  1EW2 A;  4LRA A;  5L0E A;  3IGY B;  4ZG9 A;  3T01 A;  2G9Y A;  2GSN A;  3IDD A;  4UOO A;  1URB A;  4ZGA A;  1E1Z P;  4KJD A;  2X98 A;  2W5V A;  3UNY A;  2GSO A;  1EQJ A;  3IGZ B;  5IJQ A;  5KXA A;  1EW9 A;  1KHL A;  1KH7 A;  1Y7A A;  1AJD A;  4KAV A;  5EGH A;  3MK1 A;  4UPK A;  5TJ3 A;  1ZEF A;  1E2S P;  5DLV A;  3BDH A;  3UN5 A;  2W5S A;  3OT9 A;  1EI6 A;  4LRD A;  4FDJ A;  4KM4 A;  4LR9 A;  1ANJ A;  3UN2 A;  4NWX A;  1ZEB A;  2W8D A;  1E3C P;  1FSU A;  4CXK A;  2IUC B;  1ED8 A;  4UOP A;  2RH6 A;  2GLQ A;  1ZED A;  4KAY A;  4MY4 A;  4UPH A;  4UPL A;  1HJK A;  2W5T A;  1ELZ A;  3T02 A;  1EJJ A;  4LR7 A;  3SZZ A;  2VQR A;  2W8S A;  4QAX A;  3SZY A;  3WAW A;  1KH5 A;  5LRM A;  3BDG A;  3NKO A;  3NKP A;  4LR2 A;  3M8W A;  2GSU A;  2D1G A;  3E2D A;  1KHN A;  3KD8 A;  2XRG A;  2ANH A;  3M8Y A;  4LR8 A;  4TN0 A;  3WAV A;  1ELY A;  5INH A;  5LRN A;  3LXQ A;  4B56 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...