1EQJA

Crystal structure of phosphoglycerate mutase from bacillus stearothermophilus complexed with 2-phosphoglycerate
Total Genus 192
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
192
Knots found
sequence length
508
structure length
508
Chain Sequence
KKPVALIILDGFALRDETYGNAVAQANKPNFDRYWNEYPHTTLKACGEAVGLPEGQMGNSEVGHLNIGAGRIVYQSLTRINIAIREGEFDRNETFLAAMNHVKQHGTSLHLFGLLSDGGVHSHIHHLYALLRLAAKEGVKRVYIHGFLDGRDVGPQTAPQYIKELQEKIKEYGVGEIATLSGRYYSMDRDKRWDRVEKAYRAMVYGEGPTYRDPLECIEDSYKHGIYDEFVLPSVIVREDGRPVATIQDNDAIIFYNFRPDRAIQISNTFTNEDFREFDRGPKHPKHLFFVCLTHFSETVAGYVAFKPTNLDNTIGEVLSQHGLRQLRIAETEKYPHVTFFMSGGREEEFPGEDRILINSPKVPTYDLKPEMSAYEVTDALLKEIEADKYDAIILNYANPDMVGHSGKLEPTIKAVEAVDECLGKVVDAILAKGGIAIITADHGNADEVLTPDGKPQTAHTTNPVPVIVTKKGIKLRDGGILGDLAPTMLDLLGLPQPKEMTGKSLIV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords PHOSPHOGLYCERATE MUTASE
publication title Mechanism of catalysis of the cofactor-independent phosphoglycerate mutase from Bacillus stearothermophilus. Crystal structure of the complex with 2-phosphoglycerate.
pubmed doi rcsb
source organism Geobacillus stearothermophilus
molecule tags Isomerase
total genus 192
structure length 508
sequence length 508
other databases KnotProt 2.0: S +31
ec nomenclature ec 5.4.2.12: Phosphoglycerate mutase (2,3-diphosphoglycerate-independent).
pdb deposition date 2000-04-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01676 Metalloenzyme Metalloenzyme superfamily
A PF06415 iPGM_N BPG-independent PGAM N-terminus (iPGM_N)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 1eqjA02
3.40.1450.10 Alpha Beta 3-Layer(aba) Sandwich 2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain BPG-independent phosphoglycerate mutase, domain B 1eqjA01
1EI6A 5LQQA 4LR2A 1ALIA 4ZG7A 1E33P 3SZZA 1SHNA 1HQAA 4UORA 5LIAA 3NKPA 5L0KA 3NKRA 5KXAA 3M8WA 3NKMA 1KH7A 5IJQA 3OT9A 3TG0A 4ZG9A 1ELXA 5EGHA 2ANHA 1ED9A 4LR9A 3Q3QA 2G9YA 1AJBA 3IGYB 3KD8A 3M8ZA 3SZYA 1E3CP 4KJDA 4CYSA 4CXKA 2IFYA 1EJJA 4GTXA 4FDIA 4CXUA 1ELZA 3WAYA 1ALHA 2GLQA 4MY4A 3TX0A 3BDGA 2D1GA 1O98A 3WAWA 1EW8A 4LQYA 1EQJA 4UOPA 1K7HA 1ANIA 3NKOA 1E2SP 4B56A 1AUKA 4LR7A 2QZUA 3UNYA 2GSNA 1ED8A 3E2DA 4NWJA 1ALKA 4YR1A 2W5QA 4LREA 3A52A 5INHA 4KM4A 1KH9A 2W8DA 1KH5A 2VQRA 1HJKA 4GTZA 5LRNA 1P49A 4CXSA 4FDJA 3UN2A 3UO0A 2W5VA 4MIVA 5IJSA 1AJCA 1URBA 3WBHA 2IUCB 3NVLA 3UN3A 1FSUA 2GA3A 2RH6A 5K4PA 3M7VA 5AJ9A 4TN0A 2W5RA 4MHXA 1KHJA 2XR9A 3UN5A 3MK0A 4LR8A 3CMRA 4QAXA 5DLVA 4LRAA 2W8SA 1KHKA 3MK1A 1HDHA 2ZKTA 3T00A 1KHLA 1N2LA 1ANJA 2XRGA 3LXQA 5GOVA 5L0EA 2W5XA 3BDGB 3ED4A 1Y7AA 5HRTA 1KHNA 1Y6VA 2X98A 4LRDA 1E1ZP 1O99A 4UPIA 5LRMA 2W5SA 4LRBA 4NWXA 1N2KA 4GTWA 4ZGAA 4UPKA 4UPHA 5EGEA 3WAXA 1ZEFA 1AJAA 3IDDA 5DLWA 3BDFA 4ZG6A 1B8JA 1SHQA 1URAA 1EW2A 1ZEBA 2GSOA 2IUCA 3T01A 4KAVA 5DLTA 1ALJA 1AJDA 3M8YA 1ZEDA 3DPCA 1ELYA 3DYCA 3NKQA 2W5TA 4KAYA 5C66A 3IGZB 4KJGA 2W5WA 4UOOA 2GSUA 4LRCA 4N7TA 4GTYA 3T02A 3B5QA 3BDHA 5TJ3A 4LRFA 3WAVA 4UPLA 5L0BA 3NKNA 3TWZA 5GRRA 1EW9A 1KH4A 4CYRA 3MK2A
chains in the Genus database with same CATH superfamily
1EI6A 5LQQA 4LR2A 1ALIA 4ZG7A 1E33P 3SZZA 1SHNA 1HQAA 4UORA 5LIAA 3NKPA 5L0KA 3NKRA 5KXAA 3M8WA 3NKMA 1KH7A 5IJQA 3OT9A 3TG0A 4ZG9A 1ELXA 5EGHA 2ANHA 1ED9A 4LR9A 3Q3QA 2G9YA 1AJBA 3IGYB 3KD8A 3M8ZA 3SZYA 1E3CP 4KJDA 4CYSA 4CXKA 2IFYA 1EJJA 4GTXA 4FDIA 4CXUA 1ELZA 3WAYA 1ALHA 2GLQA 4MY4A 3TX0A 3BDGA 2D1GA 1O98A 3WAWA 1EW8A 4LQYA 1EQJA 4UOPA 1K7HA 1ANIA 3NKOA 1E2SP 4B56A 1AUKA 4LR7A 2QZUA 3UNYA 2GSNA 1ED8A 3E2DA 4NWJA 1ALKA 4YR1A 2W5QA 4LREA 3A52A 5INHA 4KM4A 1KH9A 2W8DA 1KH5A 2VQRA 1HJKA 4GTZA 5LRNA 1P49A 4CXSA 4FDJA 3UN2A 3UO0A 2W5VA 4MIVA 5IJSA 1AJCA 1URBA 3WBHA 2IUCB 3NVLA 3UN3A 1FSUA 2GA3A 2RH6A 5K4PA 3M7VA 5AJ9A 4TN0A 2W5RA 4MHXA 1KHJA 2XR9A 3UN5A 3MK0A 4LR8A 3CMRA 4QAXA 5DLVA 4LRAA 2W8SA 1KHKA 3MK1A 1HDHA 2ZKTA 3T00A 1KHLA 1N2LA 1ANJA 2XRGA 3LXQA 5GOVA 5L0EA 2W5XA 3BDGB 3ED4A 1Y7AA 5HRTA 1KHNA 1Y6VA 2X98A 4LRDA 1E1ZP 1O99A 4UPIA 5LRMA 2W5SA 4LRBA 4NWXA 1N2KA 4GTWA 4ZGAA 4UPKA 4UPHA 5EGEA 3WAXA 1ZEFA 1AJAA 3IDDA 5DLWA 3BDFA 4ZG6A 1B8JA 1SHQA 1URAA 1EW2A 1ZEBA 2GSOA 2IUCA 3T01A 4KAVA 5DLTA 1ALJA 1AJDA 3M8YA 1ZEDA 3DPCA 1ELYA 3DYCA 3NKQA 2W5TA 4KAYA 5C66A 3IGZB 4KJGA 2W5WA 4UOOA 2GSUA 4LRCA 4N7TA 4GTYA 3T02A 3B5QA 3BDHA 5TJ3A 4LRFA 3WAVA 4UPLA 5L0BA 3NKNA 3TWZA 5GRRA 1EW9A 1KH4A 4CYRA 3MK2A
chains in the Genus database with same CATH topology
1EI6A 5LQQA 4LR2A 1ALIA 4ZG7A 1E33P 3SZZA 1SHNA 1HQAA 4UORA 5LIAA 3NKPA 5L0KA 3NKRA 5KXAA 3M8WA 3NKMA 1KH7A 5IJQA 3OT9A 3TG0A 4ZG9A 1ELXA 5EGHA 2ANHA 1ED9A 4LR9A 3Q3QA 2G9YA 1AJBA 3IGYB 3KD8A 3M8ZA 3SZYA 1E3CP 4KJDA 4CYSA 4CXKA 2IFYA 1EJJA 4GTXA 4FDIA 4CXUA 1ELZA 3WAYA 1ALHA 2GLQA 4MY4A 3TX0A 3BDGA 2D1GA 1O98A 3WAWA 1EW8A 4LQYA 1EQJA 4UOPA 1K7HA 1ANIA 3NKOA 1E2SP 4B56A 1AUKA 4LR7A 2QZUA 3UNYA 2GSNA 1ED8A 3E2DA 4NWJA 1ALKA 4YR1A 2W5QA 4LREA 3A52A 5INHA 4KM4A 1KH9A 2W8DA 1KH5A 2VQRA 1HJKA 4GTZA 5LRNA 1P49A 4CXSA 4FDJA 3UN2A 3UO0A 2W5VA 4MIVA 5IJSA 1AJCA 1URBA 3WBHA 2IUCB 3NVLA 3UN3A 1FSUA 2GA3A 2RH6A 5K4PA 3M7VA 5AJ9A 4TN0A 2W5RA 4MHXA 1KHJA 2XR9A 3UN5A 3MK0A 4LR8A 3CMRA 4QAXA 5DLVA 4LRAA 2W8SA 1KHKA 3MK1A 1HDHA 2ZKTA 3T00A 1KHLA 1N2LA 1ANJA 2XRGA 3LXQA 5GOVA 5L0EA 2W5XA 3BDGB 3ED4A 1Y7AA 5HRTA 1KHNA 1Y6VA 2X98A 4LRDA 1E1ZP 1O99A 4UPIA 5LRMA 2W5SA 4LRBA 4NWXA 1N2KA 4GTWA 4ZGAA 4UPKA 4UPHA 5EGEA 3WAXA 1ZEFA 1AJAA 3IDDA 5DLWA 3BDFA 4ZG6A 1B8JA 1SHQA 1URAA 1EW2A 1ZEBA 2GSOA 2IUCA 3T01A 4KAVA 5DLTA 1ALJA 1AJDA 3M8YA 1ZEDA 3DPCA 1ELYA 3DYCA 3NKQA 2W5TA 4KAYA 5C66A 3IGZB 4KJGA 2W5WA 4UOOA 2GSUA 4LRCA 4N7TA 4GTYA 3T02A 3B5QA 3BDHA 5TJ3A 4LRFA 3WAVA 4UPLA 5L0BA 3NKNA 3TWZA 5GRRA 1EW9A 1KH4A 4CYRA 3MK2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1EI6 A;  5LQQ A;  4LR2 A;  1ALI A;  4ZG7 A;  1E33 P;  3SZZ A;  1SHN A;  1HQA A;  4UOR A;  5LIA A;  3NKP A;  5L0K A;  3NKR A;  5KXA A;  3M8W A;  3NKM A;  1KH7 A;  5IJQ A;  3OT9 A;  3TG0 A;  4ZG9 A;  1ELX A;  5EGH A;  2ANH A;  1ED9 A;  4LR9 A;  3Q3Q A;  2G9Y A;  1AJB A;  3IGY B;  3KD8 A;  3M8Z A;  3SZY A;  1E3C P;  4KJD A;  4CYS A;  4CXK A;  2IFY A;  1EJJ A;  4GTX A;  4FDI A;  4CXU A;  1ELZ A;  3WAY A;  1ALH A;  2GLQ A;  4MY4 A;  3TX0 A;  3BDG A;  2D1G A;  1O98 A;  3WAW A;  1EW8 A;  4LQY A;  1EQJ A;  4UOP A;  1K7H A;  1ANI A;  3NKO A;  1E2S P;  4B56 A;  1AUK A;  4LR7 A;  2QZU A;  3UNY A;  2GSN A;  1ED8 A;  3E2D A;  4NWJ A;  1ALK A;  4YR1 A;  2W5Q A;  4LRE A;  3A52 A;  5INH A;  4KM4 A;  1KH9 A;  2W8D A;  1KH5 A;  2VQR A;  1HJK A;  4GTZ A;  5LRN A;  1P49 A;  4CXS A;  4FDJ A;  3UN2 A;  3UO0 A;  2W5V A;  4MIV A;  5IJS A;  1AJC A;  1URB A;  3WBH A;  2IUC B;  3NVL A;  3UN3 A;  1FSU A;  2GA3 A;  2RH6 A;  5K4P A;  3M7V A;  5AJ9 A;  4TN0 A;  2W5R A;  4MHX A;  1KHJ A;  2XR9 A;  3UN5 A;  3MK0 A;  4LR8 A;  3CMR A;  4QAX A;  5DLV A;  4LRA A;  2W8S A;  1KHK A;  3MK1 A;  1HDH A;  2ZKT A;  3T00 A;  1KHL A;  1N2L A;  1ANJ A;  2XRG A;  3LXQ A;  5GOV A;  5L0E A;  2W5X A;  3BDG B;  3ED4 A;  1Y7A A;  5HRT A;  1KHN A;  1Y6V A;  2X98 A;  4LRD A;  1E1Z P;  1O99 A;  4UPI A;  5LRM A;  2W5S A;  4LRB A;  4NWX A;  1N2K A;  4GTW A;  4ZGA A;  4UPK A;  4UPH A;  5EGE A;  3WAX A;  1ZEF A;  1AJA A;  3IDD A;  5DLW A;  3BDF A;  4ZG6 A;  1B8J A;  1SHQ A;  1URA A;  1EW2 A;  1ZEB A;  2GSO A;  2IUC A;  3T01 A;  4KAV A;  5DLT A;  1ALJ A;  1AJD A;  3M8Y A;  1ZED A;  3DPC A;  1ELY A;  3DYC A;  3NKQ A;  2W5T A;  4KAY A;  5C66 A;  3IGZ B;  4KJG A;  2W5W A;  4UOO A;  2GSU A;  4LRC A;  4N7T A;  4GTY A;  3T02 A;  3B5Q A;  3BDH A;  5TJ3 A;  4LRF A;  3WAV A;  4UPL A;  5L0B A;  3NKN A;  3TWZ A;  5GRR A;  1EW9 A;  1KH4 A;  4CYR A;  3MK2 A; 
#chains in the Genus database with same CATH topology
 1EI6 A;  5LQQ A;  4LR2 A;  1ALI A;  4ZG7 A;  1E33 P;  3SZZ A;  1SHN A;  1HQA A;  4UOR A;  5LIA A;  3NKP A;  5L0K A;  3NKR A;  5KXA A;  3M8W A;  3NKM A;  1KH7 A;  5IJQ A;  3OT9 A;  3TG0 A;  4ZG9 A;  1ELX A;  5EGH A;  2ANH A;  1ED9 A;  4LR9 A;  3Q3Q A;  2G9Y A;  1AJB A;  3IGY B;  3KD8 A;  3M8Z A;  3SZY A;  1E3C P;  4KJD A;  4CYS A;  4CXK A;  2IFY A;  1EJJ A;  4GTX A;  4FDI A;  4CXU A;  1ELZ A;  3WAY A;  1ALH A;  2GLQ A;  4MY4 A;  3TX0 A;  3BDG A;  2D1G A;  1O98 A;  3WAW A;  1EW8 A;  4LQY A;  1EQJ A;  4UOP A;  1K7H A;  1ANI A;  3NKO A;  1E2S P;  4B56 A;  1AUK A;  4LR7 A;  2QZU A;  3UNY A;  2GSN A;  1ED8 A;  3E2D A;  4NWJ A;  1ALK A;  4YR1 A;  2W5Q A;  4LRE A;  3A52 A;  5INH A;  4KM4 A;  1KH9 A;  2W8D A;  1KH5 A;  2VQR A;  1HJK A;  4GTZ A;  5LRN A;  1P49 A;  4CXS A;  4FDJ A;  3UN2 A;  3UO0 A;  2W5V A;  4MIV A;  5IJS A;  1AJC A;  1URB A;  3WBH A;  2IUC B;  3NVL A;  3UN3 A;  1FSU A;  2GA3 A;  2RH6 A;  5K4P A;  3M7V A;  5AJ9 A;  4TN0 A;  2W5R A;  4MHX A;  1KHJ A;  2XR9 A;  3UN5 A;  3MK0 A;  4LR8 A;  3CMR A;  4QAX A;  5DLV A;  4LRA A;  2W8S A;  1KHK A;  3MK1 A;  1HDH A;  2ZKT A;  3T00 A;  1KHL A;  1N2L A;  1ANJ A;  2XRG A;  3LXQ A;  5GOV A;  5L0E A;  2W5X A;  3BDG B;  3ED4 A;  1Y7A A;  5HRT A;  1KHN A;  1Y6V A;  2X98 A;  4LRD A;  1E1Z P;  1O99 A;  4UPI A;  5LRM A;  2W5S A;  4LRB A;  4NWX A;  1N2K A;  4GTW A;  4ZGA A;  4UPK A;  4UPH A;  5EGE A;  3WAX A;  1ZEF A;  1AJA A;  3IDD A;  5DLW A;  3BDF A;  4ZG6 A;  1B8J A;  1SHQ A;  1URA A;  1EW2 A;  1ZEB A;  2GSO A;  2IUC A;  3T01 A;  4KAV A;  5DLT A;  1ALJ A;  1AJD A;  3M8Y A;  1ZED A;  3DPC A;  1ELY A;  3DYC A;  3NKQ A;  2W5T A;  4KAY A;  5C66 A;  3IGZ B;  4KJG A;  2W5W A;  4UOO A;  2GSU A;  4LRC A;  4N7T A;  4GTY A;  3T02 A;  3B5Q A;  3BDH A;  5TJ3 A;  4LRF A;  3WAV A;  4UPL A;  5L0B A;  3NKN A;  3TWZ A;  5GRR A;  1EW9 A;  1KH4 A;  4CYR A;  3MK2 A; 
#chains in the Genus database with same CATH homology
 1EI6 A;  5LQQ A;  4LR2 A;  1ALI A;  4ZG7 A;  1E33 P;  3SZZ A;  1SHN A;  1HQA A;  4UOR A;  5LIA A;  3NKP A;  5L0K A;  3NKR A;  5KXA A;  3M8W A;  3NKM A;  1KH7 A;  5IJQ A;  3OT9 A;  3TG0 A;  4ZG9 A;  1ELX A;  5EGH A;  2ANH A;  1ED9 A;  4LR9 A;  3Q3Q A;  2G9Y A;  1AJB A;  3IGY B;  3KD8 A;  3M8Z A;  3SZY A;  1E3C P;  4KJD A;  4CYS A;  4CXK A;  2IFY A;  1EJJ A;  4GTX A;  4FDI A;  4CXU A;  1ELZ A;  3WAY A;  1ALH A;  2GLQ A;  4MY4 A;  3TX0 A;  3BDG A;  2D1G A;  1O98 A;  3WAW A;  1EW8 A;  4LQY A;  1EQJ A;  4UOP A;  1K7H A;  1ANI A;  3NKO A;  1E2S P;  4B56 A;  1AUK A;  4LR7 A;  2QZU A;  3UNY A;  2GSN A;  1ED8 A;  3E2D A;  4NWJ A;  1ALK A;  4YR1 A;  2W5Q A;  4LRE A;  3A52 A;  5INH A;  4KM4 A;  1KH9 A;  2W8D A;  1KH5 A;  2VQR A;  1HJK A;  4GTZ A;  5LRN A;  1P49 A;  4CXS A;  4FDJ A;  3UN2 A;  3UO0 A;  2W5V A;  4MIV A;  5IJS A;  1AJC A;  1URB A;  3WBH A;  2IUC B;  3NVL A;  3UN3 A;  1FSU A;  2GA3 A;  2RH6 A;  5K4P A;  3M7V A;  5AJ9 A;  4TN0 A;  2W5R A;  4MHX A;  1KHJ A;  2XR9 A;  3UN5 A;  3MK0 A;  4LR8 A;  3CMR A;  4QAX A;  5DLV A;  4LRA A;  2W8S A;  1KHK A;  3MK1 A;  1HDH A;  2ZKT A;  3T00 A;  1KHL A;  1N2L A;  1ANJ A;  2XRG A;  3LXQ A;  5GOV A;  5L0E A;  2W5X A;  3BDG B;  3ED4 A;  1Y7A A;  5HRT A;  1KHN A;  1Y6V A;  2X98 A;  4LRD A;  1E1Z P;  1O99 A;  4UPI A;  5LRM A;  2W5S A;  4LRB A;  4NWX A;  1N2K A;  4GTW A;  4ZGA A;  4UPK A;  4UPH A;  5EGE A;  3WAX A;  1ZEF A;  1AJA A;  3IDD A;  5DLW A;  3BDF A;  4ZG6 A;  1B8J A;  1SHQ A;  1URA A;  1EW2 A;  1ZEB A;  2GSO A;  2IUC A;  3T01 A;  4KAV A;  5DLT A;  1ALJ A;  1AJD A;  3M8Y A;  1ZED A;  3DPC A;  1ELY A;  3DYC A;  3NKQ A;  2W5T A;  4KAY A;  5C66 A;  3IGZ B;  4KJG A;  2W5W A;  4UOO A;  2GSU A;  4LRC A;  4N7T A;  4GTY A;  3T02 A;  3B5Q A;  3BDH A;  5TJ3 A;  4LRF A;  3WAV A;  4UPL A;  5L0B A;  3NKN A;  3TWZ A;  5GRR A;  1EW9 A;  1KH4 A;  4CYR A;  3MK2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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