2EUAA

Structure and mechanism of menf, the menaquinone-specific isochorismate synthase from escherichia coli
Total Genus 128
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
128
sequence length
428
structure length
428
Chain Sequence
QSLTTALENLLRHLSQEIPATPGIRVIDIPFPLKDAFDALSWLASQQTYPQFYWQQRNGDEEAVVLGAITRFTSLDQAQRFLRQHPEHADLRIWGLNAFDPSQGNLLLPRLEWRRCGGKATLRLTLFSESSLQHDAIQAKEFIATLVSIKPLPGLHLTTTREQHWPDKTGWTQLIELATKTIAEGELDKVVLARATDLHFASPVNAAAMMAASRRLNLNCYHFYMAFDGENAFLGSSPERLWRRRDKALRTEALAGTVANNPDDKQAQQLGEWLMADDKNQRENMLVVEDICQRLQADTQTLDVLPPQVLRLRKVQHLRRCIWTSLNKADDVICLHQLQPTAAVAGLPRDLARQFIARHEPFTREWYAGSAGYLSLQQSEFCVSLRSAKISGNVVRLYAGAGIVRGSDPEQEWQEIDNKAAGLRTLLQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Isomerase
molecule keywords Menaquinone-specific isochorismate synthase
publication title Lysine 190 is the catalytic base in MenF, the menaquinone-specific isochorismate synthase from Escherichia coli: implications for an enzyme family.
pubmed doi rcsb
source organism Escherichia coli
total genus 128
structure length 428
sequence length 428
chains with identical sequence B
ec nomenclature ec 5.4.4.2: Isochorismate synthase.
pdb deposition date 2005-10-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00425 Chorismate_bind chorismate binding enzyme
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.120.10 Alpha Beta 4-Layer Sandwich Anthranilate synthase Anthranilate synthase 2euaA00
5KCKA 1K0EA 3R74A 3R75A 2FN1A 3GSEA 5JZDA 3RV9A 1QDLA 3VEHA 5JXZA 3RV8A 3BZMA 1K0GA 3BZNA 5JY9A 3HWOA 3LOGA 1I7QA 5JY4B 1I7SA 2G5FA 2FN0A 5CWAA 5JY4A 3ST6A 2EUAA 1I1QA 3OS6A 2I6YA 3H9MA 5JY8A 3RV6A 3R76A 3RV7A 4GRHA
chains in the Genus database with same CATH superfamily
5KCKA 1K0EA 3R74A 3R75A 2FN1A 3GSEA 5JZDA 3RV9A 1QDLA 3VEHA 5JXZA 3RV8A 3BZMA 1K0GA 3BZNA 5JY9A 3HWOA 3LOGA 1I7QA 5JY4B 1I7SA 2G5FA 2FN0A 5CWAA 5JY4A 3ST6A 2EUAA 1I1QA 3OS6A 2I6YA 3H9MA 5JY8A 3RV6A 3R76A 3RV7A 4GRHA
chains in the Genus database with same CATH topology
5KCKA 1K0EA 3R74A 3R75A 2FN1A 3GSEA 5JZDA 3RV9A 1QDLA 3VEHA 5JXZA 3RV8A 3BZMA 1K0GA 3BZNA 5JY9A 3HWOA 3LOGA 1I7QA 5JY4B 1I7SA 2G5FA 2FN0A 5CWAA 5JY4A 3ST6A 2EUAA 1I1QA 3OS6A 2I6YA 3H9MA 5JY8A 3RV6A 3R76A 3RV7A 4GRHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5KCK A;  1K0E A;  3R74 A;  3R75 A;  2FN1 A;  3GSE A;  5JZD A;  3RV9 A;  1QDL A;  3VEH A;  5JXZ A;  3RV8 A;  3BZM A;  1K0G A;  3BZN A;  5JY9 A;  3HWO A;  3LOG A;  1I7Q A;  5JY4 B;  1I7S A;  2G5F A;  2FN0 A;  5CWA A;  5JY4 A;  3ST6 A;  2EUA A;  1I1Q A;  3OS6 A;  2I6Y A;  3H9M A;  5JY8 A;  3RV6 A;  3R76 A;  3RV7 A;  4GRH A; 
#chains in the Genus database with same CATH topology
 5KCK A;  1K0E A;  3R74 A;  3R75 A;  2FN1 A;  3GSE A;  5JZD A;  3RV9 A;  1QDL A;  3VEH A;  5JXZ A;  3RV8 A;  3BZM A;  1K0G A;  3BZN A;  5JY9 A;  3HWO A;  3LOG A;  1I7Q A;  5JY4 B;  1I7S A;  2G5F A;  2FN0 A;  5CWA A;  5JY4 A;  3ST6 A;  2EUA A;  1I1Q A;  3OS6 A;  2I6Y A;  3H9M A;  5JY8 A;  3RV6 A;  3R76 A;  3RV7 A;  4GRH A; 
#chains in the Genus database with same CATH homology
 5KCK A;  1K0E A;  3R74 A;  3R75 A;  2FN1 A;  3GSE A;  5JZD A;  3RV9 A;  1QDL A;  3VEH A;  5JXZ A;  3RV8 A;  3BZM A;  1K0G A;  3BZN A;  5JY9 A;  3HWO A;  3LOG A;  1I7Q A;  5JY4 B;  1I7S A;  2G5F A;  2FN0 A;  5CWA A;  5JY4 A;  3ST6 A;  2EUA A;  1I1Q A;  3OS6 A;  2I6Y A;  3H9M A;  5JY8 A;  3RV6 A;  3R76 A;  3RV7 A;  4GRH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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