2FU5A

Structure of rab8 in complex with mss4
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
117
structure length
107
Chain Sequence
QGHMVSAEGRNRKAVLCQRCGSRVLQPGTALFSRRQLFLPSMRKDGDLLQEHWLVEDMFIFENVGFTKDVGNIKFLVCADCEIGPIGWHCLDDKNSFYVALERVSHE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Signaling protein
molecule keywords Guanine nucleotide exchange factor MSS4
publication title Nucleotide exchange via local protein unfolding-structure of Rab8 in complex with MSS4
pubmed doi rcsb
source organism Homo sapiens
total genus 23
structure length 107
sequence length 117
chains with identical sequence B
ec nomenclature
pdb deposition date 2006-01-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04421 Mss4 Mss4 protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.150.10 Mainly Beta Beta Complex Metal Binding Protein, Guanine Nucleotide Exchange Factor; Chain A Metal Binding Protein, Guanine Nucleotide Exchange Factor; Chain A 2fu5A00
2FU5A 1TXJA 2LOYA 3EBMA 1FWQA 1YZ1A 2KWBA 1H6QA 2HR9A 1H7YA 1HXRA 3P3KA
chains in the Genus database with same CATH superfamily
2RQBA 1TXJA 4A2XA 2KZNA 3WX2A 5F9HA 2KWBA 1H6QA 2HR9A 4V30A 1H7YA 2K8DA 2LVLA 4V31A 3CEZA 3E0MA 3ZD6A 3WX1A 4AY2A 4TZUA 5AMHA 3FACA 3HCIA 2W4RA 3LRNA 1L1DA 3NCUA 5F98A 2KV1A 2QFDA 3GA3A 3OG8A 1HXRA 3P3KA 2RMJA 3MAOA 2FU5A 2RQAA 3HCGA 4TZCA 2QFBA 3EBMA 3ZD7A 4A2VA 3EQTA 4CI3B 3LRRA 1FWQA 1YZ1A 3HCHA 5F9FA 3CXKA 3E0OA 4CI1B 2LOYA 4TZ4C 4BPBA 4V2YA 3HCJA 2YKGA 4V2ZA 3DJMA 4CI2B 5E3HA
chains in the Genus database with same CATH topology
2RQBA 1TXJA 4A2XA 5F9HA 2KWBA 1H6QA 2HR9A 1H7YA 2LVLA 3ZD6A 4AY2A 3FACA 2W4RA 3LRNA 3NCUA 5F98A 2QFDA 3GA3A 3OG8A 1HXRA 3P3KA 2RMJA 2FU5A 2RQAA 3ZD7A 2QFBA 3EBMA 4A2VA 3EQTA 3LRRA 1FWQA 1YZ1A 5F9FA 2LOYA 4BPBA 2YKGA 3DJMA 5E3HA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2FU5 A;  1TXJ A;  2LOY A;  3EBM A;  1FWQ A;  1YZ1 A;  2KWB A;  1H6Q A;  2HR9 A;  1H7Y A;  1HXR A;  3P3K A; 
#chains in the Genus database with same CATH topology
 2RQB A;  1TXJ A;  4A2X A;  2KZN A;  3WX2 A;  5F9H A;  2KWB A;  1H6Q A;  2HR9 A;  4V30 A;  1H7Y A;  2K8D A;  2LVL A;  4V31 A;  3CEZ A;  3E0M A;  3ZD6 A;  3WX1 A;  4AY2 A;  4TZU A;  5AMH A;  3FAC A;  3HCI A;  2W4R A;  3LRN A;  1L1D A;  3NCU A;  5F98 A;  2KV1 A;  2QFD A;  3GA3 A;  3OG8 A;  1HXR A;  3P3K A;  2RMJ A;  3MAO A;  2FU5 A;  2RQA A;  3HCG A;  4TZC A;  2QFB A;  3EBM A;  3ZD7 A;  4A2V A;  3EQT A;  4CI3 B;  3LRR A;  1FWQ A;  1YZ1 A;  3HCH A;  5F9F A;  3CXK A;  3E0O A;  4CI1 B;  2LOY A;  4TZ4 C;  4BPB A;  4V2Y A;  3HCJ A;  2YKG A;  4V2Z A;  3DJM A;  4CI2 B;  5E3H A; 
#chains in the Genus database with same CATH homology
 2RQB A;  1TXJ A;  4A2X A;  5F9H A;  2KWB A;  1H6Q A;  2HR9 A;  1H7Y A;  2LVL A;  3ZD6 A;  4AY2 A;  3FAC A;  2W4R A;  3LRN A;  3NCU A;  5F98 A;  2QFD A;  3GA3 A;  3OG8 A;  1HXR A;  3P3K A;  2RMJ A;  2FU5 A;  2RQA A;  3ZD7 A;  2QFB A;  3EBM A;  4A2V A;  3EQT A;  3LRR A;  1FWQ A;  1YZ1 A;  5F9F A;  2LOY A;  4BPB A;  2YKG A;  3DJM A;  5E3H A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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