2I6YA

Structure and mechanism of mycobacterium tuberculosis salicylate synthase, mbti
Total Genus 119
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
119
sequence length
433
structure length
419
Chain Sequence
SIPMPAGVNPADLAAELAAVVTESVDEDYLLYECDGQWVLAAGVQAMVELDSDELRVIRDGVTRRQQWSGRPGAALGEAVDRLLLETDQAFGWVAFEFGVHRYGLQQRLAPHTPLARVFSPRTRIMVSEKEIRLFDAGIRHREAIDRLLATGVREVPQSRSVDVSDDPSGFRRRVAVAVDEIAAGRYHKVILSRCVEVPFAIDFPLTYRLGRRHNTPVRSFLLQLGGIRALGYSPELVTAVRADGVVITEPLAGTRALGDLESNSKEIVEHAISVRSSLEEITDIAEPGSAAVIDFMTVRSVQHLGSTIRARLDPSSDRMAALEALFPAVTASGIPKAAGVEAIFRLDECPRGLYSGAVVMLSADGGLDAALTLRAAYQVGGRTWLRAGAGIIEESEPEREFEETCEKLSTLTPYLVAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Lyase
molecule keywords Anthranilate synthase component I, putative
publication title Structure and mechanism of MbtI, the salicylate synthase from Mycobacterium tuberculosis
pubmed doi rcsb
source organism Mycobacterium tuberculosis
total genus 119
structure length 419
sequence length 433
ec nomenclature ec 4.2.99.21: Isochorismate lyase.
pdb deposition date 2006-08-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00425 Chorismate_bind chorismate binding enzyme
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.120.10 Alpha Beta 4-Layer Sandwich Anthranilate synthase Anthranilate synthase 2i6yA00
2FN0A 1K0EA 3R74A 3H9MA 5JY4B 5JY9A 2FN1A 5CWAA 3R76A 1QDLA 3BZMA 1K0GA 3GSEA 3RV6A 3HWOA 5JXZA 1I7SA 1I7QA 1I1QA 2I6YA 3R75A 4GRHA 3VEHA 2G5FA 2EUAA 5JY4A 3RV9A 5JZDA 3ST6A 3LOGA 5JY8A 5KCKA 3OS6A 3RV7A 3RV8A 3BZNA
chains in the Genus database with same CATH superfamily
2FN0A 1K0EA 3R74A 3H9MA 5JY4B 5JY9A 2FN1A 5CWAA 3R76A 1QDLA 3BZMA 1K0GA 3GSEA 3RV6A 3HWOA 5JXZA 1I7SA 1I7QA 1I1QA 2I6YA 3R75A 4GRHA 3VEHA 2G5FA 2EUAA 5JY4A 3RV9A 5JZDA 3ST6A 3LOGA 5JY8A 5KCKA 3OS6A 3RV7A 3RV8A 3BZNA
chains in the Genus database with same CATH topology
2FN0A 1K0EA 3R74A 3H9MA 5JY4B 5JY9A 2FN1A 5CWAA 3R76A 1QDLA 3BZMA 1K0GA 3GSEA 3RV6A 3HWOA 5JXZA 1I7SA 1I7QA 1I1QA 2I6YA 3R75A 4GRHA 3VEHA 2G5FA 2EUAA 5JY4A 3RV9A 5JZDA 3ST6A 3LOGA 5JY8A 5KCKA 3OS6A 3RV7A 3RV8A 3BZNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2FN0 A;  1K0E A;  3R74 A;  3H9M A;  5JY4 B;  5JY9 A;  2FN1 A;  5CWA A;  3R76 A;  1QDL A;  3BZM A;  1K0G A;  3GSE A;  3RV6 A;  3HWO A;  5JXZ A;  1I7S A;  1I7Q A;  1I1Q A;  2I6Y A;  3R75 A;  4GRH A;  3VEH A;  2G5F A;  2EUA A;  5JY4 A;  3RV9 A;  5JZD A;  3ST6 A;  3LOG A;  5JY8 A;  5KCK A;  3OS6 A;  3RV7 A;  3RV8 A;  3BZN A; 
#chains in the Genus database with same CATH topology
 2FN0 A;  1K0E A;  3R74 A;  3H9M A;  5JY4 B;  5JY9 A;  2FN1 A;  5CWA A;  3R76 A;  1QDL A;  3BZM A;  1K0G A;  3GSE A;  3RV6 A;  3HWO A;  5JXZ A;  1I7S A;  1I7Q A;  1I1Q A;  2I6Y A;  3R75 A;  4GRH A;  3VEH A;  2G5F A;  2EUA A;  5JY4 A;  3RV9 A;  5JZD A;  3ST6 A;  3LOG A;  5JY8 A;  5KCK A;  3OS6 A;  3RV7 A;  3RV8 A;  3BZN A; 
#chains in the Genus database with same CATH homology
 2FN0 A;  1K0E A;  3R74 A;  3H9M A;  5JY4 B;  5JY9 A;  2FN1 A;  5CWA A;  3R76 A;  1QDL A;  3BZM A;  1K0G A;  3GSE A;  3RV6 A;  3HWO A;  5JXZ A;  1I7S A;  1I7Q A;  1I1Q A;  2I6Y A;  3R75 A;  4GRH A;  3VEH A;  2G5F A;  2EUA A;  5JY4 A;  3RV9 A;  5JZD A;  3ST6 A;  3LOG A;  5JY8 A;  5KCK A;  3OS6 A;  3RV7 A;  3RV8 A;  3BZN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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