2IUCA

Structure of alkaline phosphatase from the antarctic bacterium tab5
Total Genus 133
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
133
Knots found
sequence length
344
structure length
340
Chain Sequence
KTPKNVILLISDGAGLSQISSTFYFKEGTPNYTQFKNIGLIKTSSSREDVTDSASGATAFSCGIKTYNAAIGVADDSTAVKSIVEIAALNNIKTGVVATSSITHATPASFYAHALNRGLEEEIAMDMTESDLDFFAGGGLNYFTSRKDKKDVLAILKGNQFTINTTGLTDFSSIASNRKMGFLLADEAMPTMESGRGNFLSAATDLAIQFLSKDNSAFFIMSEGSQIDWGGHANNASYLISEINDFDDAIGTALAFAKKDGNTLVIVTSDHETGGFTLAAKKNKREYSDYTSIGPSFSTGGHSATLIPVFAYGPGSEEFIGIYENNEIFHKILKVTKWNQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords ALKALINE PHOSPHATASE
publication title Crystal Structure of Alkaline Phosphatase from the Antarctic Bacterium Tab5.
pubmed doi rcsb
source organism Antarctic bacterium tab5
molecule tags Hydrolase
total genus 133
structure length 340
sequence length 344
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.1.3.1: Alkaline phosphatase.
pdb deposition date 2006-06-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00245 Alk_phosphatase Alkaline phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 2iucA00
1AJBA 3UO0A 5INHA 4UORA 1AJCA 3TWZA 4LRBA 1ELXA 2GSUA 2XR9A 1KHKA 4LQYA 4CXUA 5DLVA 1ALKA 3UN5A 3UN3A 3T02A 3WAYA 1N2LA 2W5TA 1EW9A 3NKPA 1SHQA 3T00A 4FDIA 4UOPA 2IUCA 5L0EA 1KH7A 1EW8A 3NKQA 3WAVA 3NKNA 4FDJA 3E2DA 2IUCB 4CYSA 4GTYA 4UPIA 4MIVA 1ZEDA 5EGEA 3OT9A 4B56A 4LR2A 4ZG7A 3KD8A 3WBHA 4LR9A 1AUKA 1B8JA 2W5XA 1AJDA 3ED4A 4LR8A 1P49A 2GSOA 1ED8A 3SZYA 1E1ZP 4NWXA 5L0BA 1KH9A 4KM4A 1ELYA 1KHLA 5IJSA 1Y6VA 4KAVA 5DLTA 1KHNA 1O98A 2W5SA 4GTWA 4LRCA 4LRFA 4GTZA 2G9YA 3BDGB 5EGHA 3CMRA 2IFYA 3NVLA 3NKMA 1ALJA 4LREA 2XRGA 5L0KA 3A52A 2W8SA 5TJ3A 1EJJA 1HDHA 3BDGA 1EW2A 4MHXA 2QZUA 1HJKA 2VQRA 4UPKA 2W8DA 2W5RA 3DYCA 1ZEFA 4KAYA 3IGYB 3MK1A 1K7HA 1KH5A 3TG0A 1KHJA 2GSNA 1FSUA 1ZEBA 1ED9A 1ALHA 5LRNA 3M7VA 3TX0A 5HRTA 2ZKTA 4KJDA 4UOOA 2ANHA 5KXAA 1ELZA 3LXQA 4LRDA 5AJ9A 2W5VA 3UN2A 3WAWA 3WAXA 1URAA 2W5QA 4CXSA 5GOVA 4ZG6A 5DLWA 4CYRA 5C66A 1HQAA 3DPCA 3M8WA 3MK0A 4UPLA 1EI6A 1KH4A 1O99A 2D1GA 5K4PA 1E2SP 3BDHA 3SZZA 3IGZB 3M8YA 3Q3QA 5IJQA 1EQJA 1AJAA 3NKRA 4N7TA 3B5QA 5LRMA 3M8ZA 4NWJA 1SHNA 4TN0A 1E3CP 3UNYA 5LQQA 4ZGAA 4LR7A 4MY4A 1E33P 4UPHA 2RH6A 3NKOA 4KJGA 1ANJA 1URBA 3IDDA 2GLQA 2X98A 4QAXA 4GTXA 1ALIA 3T01A 3MK2A 2GA3A 3BDFA 4LRAA 1N2KA 4CXKA 5GRRA 2W5WA 1ANIA 5LIAA 1Y7AA 4YR1A 4ZG9A
chains in the Genus database with same CATH superfamily
1AJBA 3UO0A 5INHA 4UORA 1AJCA 3TWZA 4LRBA 1ELXA 2GSUA 2XR9A 1KHKA 4LQYA 4CXUA 5DLVA 1ALKA 3UN5A 3UN3A 3T02A 3WAYA 1N2LA 2W5TA 1EW9A 3NKPA 1SHQA 3T00A 4FDIA 4UOPA 2IUCA 5L0EA 1KH7A 1EW8A 3NKQA 3WAVA 3NKNA 4FDJA 3E2DA 2IUCB 4CYSA 4GTYA 4UPIA 4MIVA 1ZEDA 5EGEA 3OT9A 4B56A 4LR2A 4ZG7A 3KD8A 3WBHA 4LR9A 1AUKA 1B8JA 2W5XA 1AJDA 3ED4A 4LR8A 1P49A 2GSOA 1ED8A 3SZYA 1E1ZP 4NWXA 5L0BA 1KH9A 4KM4A 1ELYA 1KHLA 5IJSA 1Y6VA 4KAVA 5DLTA 1KHNA 1O98A 2W5SA 4GTWA 4LRCA 4LRFA 4GTZA 2G9YA 3BDGB 5EGHA 3CMRA 2IFYA 3NVLA 3NKMA 1ALJA 4LREA 2XRGA 5L0KA 3A52A 2W8SA 5TJ3A 1EJJA 1HDHA 3BDGA 1EW2A 4MHXA 2QZUA 1HJKA 2VQRA 4UPKA 2W8DA 2W5RA 3DYCA 1ZEFA 4KAYA 3IGYB 3MK1A 1K7HA 1KH5A 3TG0A 1KHJA 2GSNA 1FSUA 1ZEBA 1ED9A 1ALHA 5LRNA 3M7VA 3TX0A 5HRTA 2ZKTA 4KJDA 4UOOA 2ANHA 5KXAA 1ELZA 3LXQA 4LRDA 5AJ9A 2W5VA 3UN2A 3WAWA 3WAXA 1URAA 2W5QA 4CXSA 5GOVA 4ZG6A 5DLWA 4CYRA 5C66A 1HQAA 3DPCA 3M8WA 3MK0A 4UPLA 1EI6A 1KH4A 1O99A 2D1GA 5K4PA 1E2SP 3BDHA 3SZZA 3IGZB 3M8YA 3Q3QA 5IJQA 1EQJA 1AJAA 3NKRA 4N7TA 3B5QA 5LRMA 3M8ZA 4NWJA 1SHNA 4TN0A 1E3CP 3UNYA 5LQQA 4ZGAA 4LR7A 4MY4A 1E33P 4UPHA 2RH6A 3NKOA 4KJGA 1ANJA 1URBA 3IDDA 2GLQA 2X98A 4QAXA 4GTXA 1ALIA 3T01A 3MK2A 2GA3A 3BDFA 4LRAA 1N2KA 4CXKA 5GRRA 2W5WA 1ANIA 5LIAA 1Y7AA 4YR1A 4ZG9A
chains in the Genus database with same CATH topology
1AJBA 3UO0A 5INHA 4UORA 1AJCA 3TWZA 4LRBA 1ELXA 2GSUA 2XR9A 1KHKA 4LQYA 4CXUA 5DLVA 1ALKA 3UN5A 3UN3A 3T02A 3WAYA 1N2LA 2W5TA 1EW9A 3NKPA 1SHQA 3T00A 4FDIA 4UOPA 2IUCA 5L0EA 1KH7A 1EW8A 3NKQA 3WAVA 3NKNA 4FDJA 3E2DA 2IUCB 4CYSA 4GTYA 4UPIA 4MIVA 1ZEDA 5EGEA 3OT9A 4B56A 4LR2A 4ZG7A 3KD8A 3WBHA 4LR9A 1AUKA 1B8JA 2W5XA 1AJDA 3ED4A 4LR8A 1P49A 2GSOA 1ED8A 3SZYA 1E1ZP 4NWXA 5L0BA 1KH9A 4KM4A 1ELYA 1KHLA 5IJSA 1Y6VA 4KAVA 5DLTA 1KHNA 1O98A 2W5SA 4GTWA 4LRCA 4LRFA 4GTZA 2G9YA 3BDGB 5EGHA 3CMRA 2IFYA 3NVLA 3NKMA 1ALJA 4LREA 2XRGA 5L0KA 3A52A 2W8SA 5TJ3A 1EJJA 1HDHA 3BDGA 1EW2A 4MHXA 2QZUA 1HJKA 2VQRA 4UPKA 2W8DA 2W5RA 3DYCA 1ZEFA 4KAYA 3IGYB 3MK1A 1K7HA 1KH5A 3TG0A 1KHJA 2GSNA 1FSUA 1ZEBA 1ED9A 1ALHA 5LRNA 3M7VA 3TX0A 5HRTA 2ZKTA 4KJDA 4UOOA 2ANHA 5KXAA 1ELZA 3LXQA 4LRDA 5AJ9A 2W5VA 3UN2A 3WAWA 3WAXA 1URAA 2W5QA 4CXSA 5GOVA 4ZG6A 5DLWA 4CYRA 5C66A 1HQAA 3DPCA 3M8WA 3MK0A 4UPLA 1EI6A 1KH4A 1O99A 2D1GA 5K4PA 1E2SP 3BDHA 3SZZA 3IGZB 3M8YA 3Q3QA 5IJQA 1EQJA 1AJAA 3NKRA 4N7TA 3B5QA 5LRMA 3M8ZA 4NWJA 1SHNA 4TN0A 1E3CP 3UNYA 5LQQA 4ZGAA 4LR7A 4MY4A 1E33P 4UPHA 2RH6A 3NKOA 4KJGA 1ANJA 1URBA 3IDDA 2GLQA 2X98A 4QAXA 4GTXA 1ALIA 3T01A 3MK2A 2GA3A 3BDFA 4LRAA 1N2KA 4CXKA 5GRRA 2W5WA 1ANIA 5LIAA 1Y7AA 4YR1A 4ZG9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1AJB A;  3UO0 A;  5INH A;  4UOR A;  1AJC A;  3TWZ A;  4LRB A;  1ELX A;  2GSU A;  2XR9 A;  1KHK A;  4LQY A;  4CXU A;  5DLV A;  1ALK A;  3UN5 A;  3UN3 A;  3T02 A;  3WAY A;  1N2L A;  2W5T A;  1EW9 A;  3NKP A;  1SHQ A;  3T00 A;  4FDI A;  4UOP A;  2IUC A;  5L0E A;  1KH7 A;  1EW8 A;  3NKQ A;  3WAV A;  3NKN A;  4FDJ A;  3E2D A;  2IUC B;  4CYS A;  4GTY A;  4UPI A;  4MIV A;  1ZED A;  5EGE A;  3OT9 A;  4B56 A;  4LR2 A;  4ZG7 A;  3KD8 A;  3WBH A;  4LR9 A;  1AUK A;  1B8J A;  2W5X A;  1AJD A;  3ED4 A;  4LR8 A;  1P49 A;  2GSO A;  1ED8 A;  3SZY A;  1E1Z P;  4NWX A;  5L0B A;  1KH9 A;  4KM4 A;  1ELY A;  1KHL A;  5IJS A;  1Y6V A;  4KAV A;  5DLT A;  1KHN A;  1O98 A;  2W5S A;  4GTW A;  4LRC A;  4LRF A;  4GTZ A;  2G9Y A;  3BDG B;  5EGH A;  3CMR A;  2IFY A;  3NVL A;  3NKM A;  1ALJ A;  4LRE A;  2XRG A;  5L0K A;  3A52 A;  2W8S A;  5TJ3 A;  1EJJ A;  1HDH A;  3BDG A;  1EW2 A;  4MHX A;  2QZU A;  1HJK A;  2VQR A;  4UPK A;  2W8D A;  2W5R A;  3DYC A;  1ZEF A;  4KAY A;  3IGY B;  3MK1 A;  1K7H A;  1KH5 A;  3TG0 A;  1KHJ A;  2GSN A;  1FSU A;  1ZEB A;  1ED9 A;  1ALH A;  5LRN A;  3M7V A;  3TX0 A;  5HRT A;  2ZKT A;  4KJD A;  4UOO A;  2ANH A;  5KXA A;  1ELZ A;  3LXQ A;  4LRD A;  5AJ9 A;  2W5V A;  3UN2 A;  3WAW A;  3WAX A;  1URA A;  2W5Q A;  4CXS A;  5GOV A;  4ZG6 A;  5DLW A;  4CYR A;  5C66 A;  1HQA A;  3DPC A;  3M8W A;  3MK0 A;  4UPL A;  1EI6 A;  1KH4 A;  1O99 A;  2D1G A;  5K4P A;  1E2S P;  3BDH A;  3SZZ A;  3IGZ B;  3M8Y A;  3Q3Q A;  5IJQ A;  1EQJ A;  1AJA A;  3NKR A;  4N7T A;  3B5Q A;  5LRM A;  3M8Z A;  4NWJ A;  1SHN A;  4TN0 A;  1E3C P;  3UNY A;  5LQQ A;  4ZGA A;  4LR7 A;  4MY4 A;  1E33 P;  4UPH A;  2RH6 A;  3NKO A;  4KJG A;  1ANJ A;  1URB A;  3IDD A;  2GLQ A;  2X98 A;  4QAX A;  4GTX A;  1ALI A;  3T01 A;  3MK2 A;  2GA3 A;  3BDF A;  4LRA A;  1N2K A;  4CXK A;  5GRR A;  2W5W A;  1ANI A;  5LIA A;  1Y7A A;  4YR1 A;  4ZG9 A; 
#chains in the Genus database with same CATH topology
 1AJB A;  3UO0 A;  5INH A;  4UOR A;  1AJC A;  3TWZ A;  4LRB A;  1ELX A;  2GSU A;  2XR9 A;  1KHK A;  4LQY A;  4CXU A;  5DLV A;  1ALK A;  3UN5 A;  3UN3 A;  3T02 A;  3WAY A;  1N2L A;  2W5T A;  1EW9 A;  3NKP A;  1SHQ A;  3T00 A;  4FDI A;  4UOP A;  2IUC A;  5L0E A;  1KH7 A;  1EW8 A;  3NKQ A;  3WAV A;  3NKN A;  4FDJ A;  3E2D A;  2IUC B;  4CYS A;  4GTY A;  4UPI A;  4MIV A;  1ZED A;  5EGE A;  3OT9 A;  4B56 A;  4LR2 A;  4ZG7 A;  3KD8 A;  3WBH A;  4LR9 A;  1AUK A;  1B8J A;  2W5X A;  1AJD A;  3ED4 A;  4LR8 A;  1P49 A;  2GSO A;  1ED8 A;  3SZY A;  1E1Z P;  4NWX A;  5L0B A;  1KH9 A;  4KM4 A;  1ELY A;  1KHL A;  5IJS A;  1Y6V A;  4KAV A;  5DLT A;  1KHN A;  1O98 A;  2W5S A;  4GTW A;  4LRC A;  4LRF A;  4GTZ A;  2G9Y A;  3BDG B;  5EGH A;  3CMR A;  2IFY A;  3NVL A;  3NKM A;  1ALJ A;  4LRE A;  2XRG A;  5L0K A;  3A52 A;  2W8S A;  5TJ3 A;  1EJJ A;  1HDH A;  3BDG A;  1EW2 A;  4MHX A;  2QZU A;  1HJK A;  2VQR A;  4UPK A;  2W8D A;  2W5R A;  3DYC A;  1ZEF A;  4KAY A;  3IGY B;  3MK1 A;  1K7H A;  1KH5 A;  3TG0 A;  1KHJ A;  2GSN A;  1FSU A;  1ZEB A;  1ED9 A;  1ALH A;  5LRN A;  3M7V A;  3TX0 A;  5HRT A;  2ZKT A;  4KJD A;  4UOO A;  2ANH A;  5KXA A;  1ELZ A;  3LXQ A;  4LRD A;  5AJ9 A;  2W5V A;  3UN2 A;  3WAW A;  3WAX A;  1URA A;  2W5Q A;  4CXS A;  5GOV A;  4ZG6 A;  5DLW A;  4CYR A;  5C66 A;  1HQA A;  3DPC A;  3M8W A;  3MK0 A;  4UPL A;  1EI6 A;  1KH4 A;  1O99 A;  2D1G A;  5K4P A;  1E2S P;  3BDH A;  3SZZ A;  3IGZ B;  3M8Y A;  3Q3Q A;  5IJQ A;  1EQJ A;  1AJA A;  3NKR A;  4N7T A;  3B5Q A;  5LRM A;  3M8Z A;  4NWJ A;  1SHN A;  4TN0 A;  1E3C P;  3UNY A;  5LQQ A;  4ZGA A;  4LR7 A;  4MY4 A;  1E33 P;  4UPH A;  2RH6 A;  3NKO A;  4KJG A;  1ANJ A;  1URB A;  3IDD A;  2GLQ A;  2X98 A;  4QAX A;  4GTX A;  1ALI A;  3T01 A;  3MK2 A;  2GA3 A;  3BDF A;  4LRA A;  1N2K A;  4CXK A;  5GRR A;  2W5W A;  1ANI A;  5LIA A;  1Y7A A;  4YR1 A;  4ZG9 A; 
#chains in the Genus database with same CATH homology
 1AJB A;  3UO0 A;  5INH A;  4UOR A;  1AJC A;  3TWZ A;  4LRB A;  1ELX A;  2GSU A;  2XR9 A;  1KHK A;  4LQY A;  4CXU A;  5DLV A;  1ALK A;  3UN5 A;  3UN3 A;  3T02 A;  3WAY A;  1N2L A;  2W5T A;  1EW9 A;  3NKP A;  1SHQ A;  3T00 A;  4FDI A;  4UOP A;  2IUC A;  5L0E A;  1KH7 A;  1EW8 A;  3NKQ A;  3WAV A;  3NKN A;  4FDJ A;  3E2D A;  2IUC B;  4CYS A;  4GTY A;  4UPI A;  4MIV A;  1ZED A;  5EGE A;  3OT9 A;  4B56 A;  4LR2 A;  4ZG7 A;  3KD8 A;  3WBH A;  4LR9 A;  1AUK A;  1B8J A;  2W5X A;  1AJD A;  3ED4 A;  4LR8 A;  1P49 A;  2GSO A;  1ED8 A;  3SZY A;  1E1Z P;  4NWX A;  5L0B A;  1KH9 A;  4KM4 A;  1ELY A;  1KHL A;  5IJS A;  1Y6V A;  4KAV A;  5DLT A;  1KHN A;  1O98 A;  2W5S A;  4GTW A;  4LRC A;  4LRF A;  4GTZ A;  2G9Y A;  3BDG B;  5EGH A;  3CMR A;  2IFY A;  3NVL A;  3NKM A;  1ALJ A;  4LRE A;  2XRG A;  5L0K A;  3A52 A;  2W8S A;  5TJ3 A;  1EJJ A;  1HDH A;  3BDG A;  1EW2 A;  4MHX A;  2QZU A;  1HJK A;  2VQR A;  4UPK A;  2W8D A;  2W5R A;  3DYC A;  1ZEF A;  4KAY A;  3IGY B;  3MK1 A;  1K7H A;  1KH5 A;  3TG0 A;  1KHJ A;  2GSN A;  1FSU A;  1ZEB A;  1ED9 A;  1ALH A;  5LRN A;  3M7V A;  3TX0 A;  5HRT A;  2ZKT A;  4KJD A;  4UOO A;  2ANH A;  5KXA A;  1ELZ A;  3LXQ A;  4LRD A;  5AJ9 A;  2W5V A;  3UN2 A;  3WAW A;  3WAX A;  1URA A;  2W5Q A;  4CXS A;  5GOV A;  4ZG6 A;  5DLW A;  4CYR A;  5C66 A;  1HQA A;  3DPC A;  3M8W A;  3MK0 A;  4UPL A;  1EI6 A;  1KH4 A;  1O99 A;  2D1G A;  5K4P A;  1E2S P;  3BDH A;  3SZZ A;  3IGZ B;  3M8Y A;  3Q3Q A;  5IJQ A;  1EQJ A;  1AJA A;  3NKR A;  4N7T A;  3B5Q A;  5LRM A;  3M8Z A;  4NWJ A;  1SHN A;  4TN0 A;  1E3C P;  3UNY A;  5LQQ A;  4ZGA A;  4LR7 A;  4MY4 A;  1E33 P;  4UPH A;  2RH6 A;  3NKO A;  4KJG A;  1ANJ A;  1URB A;  3IDD A;  2GLQ A;  2X98 A;  4QAX A;  4GTX A;  1ALI A;  3T01 A;  3MK2 A;  2GA3 A;  3BDF A;  4LRA A;  1N2K A;  4CXK A;  5GRR A;  2W5W A;  1ANI A;  5LIA A;  1Y7A A;  4YR1 A;  4ZG9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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