2XDIA

Tryptophan repressor with l75f mutation in its apo form (no l- tryptophan bound)
Total Genus 22
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
22
sequence length
105
structure length
105
Chain Sequence
QSPYSAAMAEQRHQEWLRFVDLLKNAYQNDLHLPLLNLMLTPDEREALGTRVRIVEELLRGEMSQRELKNEFGAGIATITRGSNSLKAAPVELRQWLEEVLLKSD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transcription
molecule keywords TRP OPERON REPRESSOR
publication title Three-Dimensional Solution NMR Structure of Apo-L75F-Trpr, a Temperature-Sensitive Mutant of the Tryptophan Repressor Protein.
pubmed doi rcsb
source organism Escherichia coli
total genus 22
structure length 105
sequence length 105
chains with identical sequence B
ec nomenclature
pdb deposition date 2010-05-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01371 Trp_repressor Trp repressor protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1270.10 Mainly Alpha Orthogonal Bundle Trp Operon Repressor; Chain A TrpR-like 2xdiA00
1TROA 2OZ9R 3WRPA 1RCSA 1TRRA 1MI7R 1WRSR 1WRTR 1ZT9A 3G1CA 1CO0A 3SSWN 3SSXN 2XDIA 1WRPR 3KORA 3FRWA 1JHGA
chains in the Genus database with same CATH superfamily
3KY7A 4MCCA 4YQ4A 1UAKA 1MI7R 1WRTR 4YQPA 4YQOA 3SSXN 4YQ6A 4YPWA 4YQQA 4YQ0A 4YPXA 4YQTA 3AXZA 2OZ9R 1UAMA 4YVGA 1UALA 4YPYA 1TROA 1WRSR 3KNUA 4YVIA 3G1CA 4YVHA 4YVJA 4YQ7A 4IG6A 4YQAA 3IEFA 4YQ1A 1WRPR 4MCBA 1P9PA 4YQBA 4YQNA 4YQ2A 4H3YA 1UAJA 4YQJA 4YQGA 4YQ9A 1RCSA 1TRRA 4YQLA 4YQRA 1CO0A 4H3ZA 4YQIA 3KORA 4YQSA 3FRWA 1JHGA 1OY5A 4YQ8A 4MCDA 3WRPA 4YQ3A 5D9FA 1ZT9A 4YQDA 3SSWN 4YQCA 4YVKA 4YPZA 4YQKA 3QUVA 2XDIA 4YQ5A
chains in the Genus database with same CATH topology
1TROA 2OZ9R 3WRPA 1RCSA 1TRRA 1MI7R 1WRSR 1WRTR 1ZT9A 3G1CA 1CO0A 3SSWN 3SSXN 2XDIA 1WRPR 3KORA 3FRWA 1JHGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1TRO A;  2OZ9 R;  3WRP A;  1RCS A;  1TRR A;  1MI7 R;  1WRS R;  1WRT R;  1ZT9 A;  3G1C A;  1CO0 A;  3SSW N;  3SSX N;  2XDI A;  1WRP R;  3KOR A;  3FRW A;  1JHG A; 
#chains in the Genus database with same CATH topology
 3KY7 A;  4MCC A;  4YQ4 A;  1UAK A;  1MI7 R;  1WRT R;  4YQP A;  4YQO A;  3SSX N;  4YQ6 A;  4YPW A;  4YQQ A;  4YQ0 A;  4YPX A;  4YQT A;  3AXZ A;  2OZ9 R;  1UAM A;  4YVG A;  1UAL A;  4YPY A;  1TRO A;  1WRS R;  3KNU A;  4YVI A;  3G1C A;  4YVH A;  4YVJ A;  4YQ7 A;  4IG6 A;  4YQA A;  3IEF A;  4YQ1 A;  1WRP R;  4MCB A;  1P9P A;  4YQB A;  4YQN A;  4YQ2 A;  4H3Y A;  1UAJ A;  4YQJ A;  4YQG A;  4YQ9 A;  1RCS A;  1TRR A;  4YQL A;  4YQR A;  1CO0 A;  4H3Z A;  4YQI A;  3KOR A;  4YQS A;  3FRW A;  1JHG A;  1OY5 A;  4YQ8 A;  4MCD A;  3WRP A;  4YQ3 A;  5D9F A;  1ZT9 A;  4YQD A;  3SSW N;  4YQC A;  4YVK A;  4YPZ A;  4YQK A;  3QUV A;  2XDI A;  4YQ5 A; 
#chains in the Genus database with same CATH homology
 1TRO A;  2OZ9 R;  3WRP A;  1RCS A;  1TRR A;  1MI7 R;  1WRS R;  1WRT R;  1ZT9 A;  3G1C A;  1CO0 A;  3SSW N;  3SSX N;  2XDI A;  1WRP R;  3KOR A;  3FRW A;  1JHG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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