2ZW3A

Structure of the connexin-26 gap junction channel at 3.5 angstrom resolution
Total Genus 59
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
59
sequence length
216
structure length
201
Chain Sequence
DWGTLQTILGGVNKHSTSIGKIWLTVLFIFRIMILVVAAKEVWGDEQADFVCNTLQPGCKNVCYDHYFPISHIRLWALQLIFVSTPALLVAMHVAYRRHEKKRKFIKGKVRIEGSLWWTYTSSIFFRVIFEAAFMYVFYVMYDGFSMQRLVKCNAWPCPNTVDCFVSRPTEKTVFTVFMIAVSGICILLNVTELCYLLIRY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Cell adhesion
molecule keywords Gap junction beta-2 protein
publication title Structure of the connexin 26 gap junction channel at 3.5 A resolution
pubmed doi rcsb
source organism Homo sapiens
total genus 59
structure length 201
sequence length 216
chains with identical sequence B, C, D, E, F
ec nomenclature
pdb deposition date 2008-12-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00029 Connexin Connexin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1440.80 Mainly Alpha Up-down Bundle de novo design (two linked rop proteins) Gap junction channel protein cysteine-rich domain 2zw3A00
2ZW3A
chains in the Genus database with same CATH superfamily
1TDPA 2RADA 2F66B 1YO7A 3FNBA 4YZCA 2F6MB 1SJ8A 2QZGA 4OAUC 4Z7HA 3FBVA 2MJFB 5HGIA 2FUG1 3SDJA 1JQOA 4I1TA 2E8GA 2A2DA 4YZDA 2YFAA 2QGMA 4G76A 2RLDA 2A2CA 2JBWA 4O1PA 4HEA1 3I9V1 4PL5A 3AJFA 3DO9A 2FU2A 2XMXA 4U6RA 2ETDA 3VA9A 3IAS1 3L0IA 5LNK1 2ZW3A 2QSBA 4Q9VA 4YZ9A 1W3SA 3DA3A 2V1CC 2XTRA 4NV2A 2JB1A 4Z7GA 4JCVE 4OAVB 2GSCA 3LJ0A 2KKMA 4PL3A 2K19A 2XTQA 3P23A 2P22B 3LJ2A 3Q8DA 3UITA 2BL7A 4DWLA 3KP9A 4GXTA 2YFBA 4O1OA 2FEFA 2CAZB 3LJ1A 3DA4A 2JAEA 2ZRRA 4PL4A 1U5KA 4AS2A 2HGKA 2IP6A 3IAM1 4AS3A 3F4MA 2L1LB 2BL8A 4HFVA 2JB2A 3B55A 3JSBA 4NV5A 2JB3A 2V6EA 2RIOA 4G75A 3FVVA
chains in the Genus database with same CATH topology
2ZW3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ZW3 A; 
#chains in the Genus database with same CATH topology
 1TDP A;  2RAD A;  2F66 B;  1YO7 A;  3FNB A;  4YZC A;  2F6M B;  1SJ8 A;  2QZG A;  4OAU C;  4Z7H A;  3FBV A;  2MJF B;  5HGI A;  2FUG 1;  3SDJ A;  1JQO A;  4I1T A;  2E8G A;  2A2D A;  4YZD A;  2YFA A;  2QGM A;  4G76 A;  2RLD A;  2A2C A;  2JBW A;  4O1P A;  4HEA 1;  3I9V 1;  4PL5 A;  3AJF A;  3DO9 A;  2FU2 A;  2XMX A;  4U6R A;  2ETD A;  3VA9 A;  3IAS 1;  3L0I A;  5LNK 1;  2ZW3 A;  2QSB A;  4Q9V A;  4YZ9 A;  1W3S A;  3DA3 A;  2V1C C;  2XTR A;  4NV2 A;  2JB1 A;  4Z7G A;  4JCV E;  4OAV B;  2GSC A;  3LJ0 A;  2KKM A;  4PL3 A;  2K19 A;  2XTQ A;  3P23 A;  2P22 B;  3LJ2 A;  3Q8D A;  3UIT A;  2BL7 A;  4DWL A;  3KP9 A;  4GXT A;  2YFB A;  4O1O A;  2FEF A;  2CAZ B;  3LJ1 A;  3DA4 A;  2JAE A;  2ZRR A;  4PL4 A;  1U5K A;  4AS2 A;  2HGK A;  2IP6 A;  3IAM 1;  4AS3 A;  3F4M A;  2L1L B;  2BL8 A;  4HFV A;  2JB2 A;  3B55 A;  3JSB A;  4NV5 A;  2JB3 A;  2V6E A;  2RIO A;  4G75 A;  3FVV A; 
#chains in the Genus database with same CATH homology
 2ZW3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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