2EGVA

Crystal structure of rrna methyltransferase with sam ligand
Total Genus 72
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
72
Knots found
sequence length
229
structure length
229
Chain Sequence
MHVFYSEERRGNLLILREGEVKHFRVRRIEKDEEFGVIHEGKIYVCKVRREDKREISCEIVEELETKLPPKDITLYQSVTVDLKTMDTIVRQATELGVLTFVPIISERSFQKEEAILKKTEKWKRIVIEAMKQSRRPIPMEIKKPVRLSDLIPESEENIILDNFYEGVKPKDVNLEAKTYSVVVGPEGGFSKRESQILREKGFKSVLLEPYTLRTETAVVSIVSILMNF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords UPF0088 protein aq_165
publication title Crystal structure of rRNA methyltransferase with SAM ligand
rcsb
source organism Aquifex aeolicus
molecule tags Rna methyltransferase
total genus 72
structure length 229
sequence length 229
chains with identical sequence B
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.193: 16S rRNA (uracil(1498)-N(3))-methyltransferase.
pdb deposition date 2007-03-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04452 Methyltrans_RNA RNA methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.240.20 Mainly Beta Beta Barrel Ribosomal Protein L25; Chain P Hypothetical PUA domain-like; domain 1 2egvA01
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 2egvA02
4PZKA 4YQGA 1VHKA 2NWAA 3AI9X 4YQOA 3DCMX 4H3YA 4YQ5A 3L8UA 5GMCA 4YQ6A 1NXZA 4YQPA 4YPXA 3OIIA 4XBOA 4YPWA 1X7PA 5FAIA 4IG6A 4YQIA 3KW2A 4YQ3A 2QMMA 3BBEA 4YQLA 1NS5A 4H3ZA 4FAKA 1J85A 4CNFA 3BBDA 4MCCA 5D9FA 4L69A 4YPZA 4YQ9A 4YQ1A 1X7OA 4YQCA 2YY8A 1Z85A 1UAJA 1UAMA 4YQ4A 3ONPA 5GM8A 4MCBA 2EGVA 4YQRA 2EGWA 4YQAA 3OIJA 3IC6A 4KDZA 4X3LA 4YVKA 3QUVA 2CX8A 4YQDA 1K3RA 1IPAA 4YQJA 3N4KA 4YVIA 3GYQA 4KGNA 1P9PA 4YQ0A 1ZJRA 1V2XA 4X3MA 4YQ2A 1OY5A 4YQBA 4J3CA 3N4JA 4MCDA 4YQNA 4JALA 5CO4A 1UALA 2I6DA 4YQSA 2Z0YA 4YQQA 4YQ7A 4CNGA 4JAKA 5GMBA 3AIAA 1V6ZA 3IEFA 2QWVA 3AXZA 3ILKA 1VHYA 4YVGA 4YVJA 3E5YA 1GZ0A 4YQ8A 3OINA 3NK7A 3KY7A 3KTYA 4CNDA 3KNUA 3NK6A 3BBHA 4YQTA 2V3KA 4YVHA 1VH0A 1UAKA 3O7BA 4YPYA 1MXIA 1TO0A 4E8BA 2HA8A 2O3AA 2V3JA 4CNEA 4RG1A 4YQKA 1O6DA
chains in the Genus database with same CATH superfamily
4PZKA 3W2WB 4YQGA 1VHKA 2NWAA 3AI9X 4YQOA 3AIIA 2RD2A 4H4KA 3DCMX 4H3YA 4YQ5A 3J7ZV 5GAGW 3L8UA 4JWGA 5GMCA 5GAHW 4WFBS 4YQ6A 2PNWA 1NXZA 4YQPA 2PICA 4YPXA 3OIIA 4XBOA 5JVHS 1QRSA 5HL7S 1X7PA 4YPWA 5FAIA 2GAEA 4IG6A 5JVGS 4YQIA 3KW2A 4JWHA 4YQ3A 2QMMA 3BBEA 4YQLA 1NS5A 2G6GA 2RE8A 1EUYA 4H3ZA 3CF5S 4FAKA 1UDXA 1J85A 4CNFA 1NYLA 3PIOS 3BBDA 4MCCA 3X1LB 5D9FA 1QRUA 3DLLS 2PI8A 4L69A 4YPZA 5BNZA 2ZJQS 1QTQA 4YQ9A 4YQ1A 1X7OA 4YQCA 4JXXA 2YY8A 1Z85A 1UAJA 1UAMA 4FMWA 4YQ4A 3ONPA 5GM8A 4MCBA 4H3SA 4UY88 2EGVA 4YQRA 2EGWA 1EUQA 4YQAA 5IZNA 4WFAS 3OIJA 3IC6A 4JWJA 2ZJPS 4KDZA 4X3LA 4YVKA 4WCES 3QUVA 4WF9S 2CX8A 4U67S 4IOAS 4YQDA 1K3RA 1IPAA 1D6KA 4YQJA 1FEUA 3N4KA 4YVIA 1EXDA 3GYQA 4KGNA 1P9PA 4YQ0A 1ZJRA 2PJJA 4V194 1V2XA 4X3MA 4YQ2A 1OY5A 4YQBA 4IO9S 4J3CA 4JYZA 3N4JA 4MCDA 4YQNA 2HZ7A 1B75A 2G5DA 4JALA 5CO4A 1UALA 5GAEW 4JWFA 2I6DA 3PIPS 4YQSA 2Z0YA 4WFNS 4YQQA 4YQ7A 4CNGA 4JAKA 5GMBA 3AIAA 2ZJRS 1V6ZA 3IEFA 4JXZA 2QWVA 3AXZA 3ILKA 2AE0X 1VHYA 4YVGA 5GADW 4P2BA 1GTRA 1ZJWA 4YVJA 1QRTA 3E5YA 1GZ0A 4YQ8A 3OINA 3NK7A 3KY7A 3KTYA 4CNDA 5DM7S 3KNUA 3NK6A 3BBHA 1O0CA 4YQTA 2V3KA 4YVHA 1VH0A 1UAKA 4IOCS 1O0BA 3O7BA 3W2VB 1MXIA 4YPYA 1TO0A 4E8BA 1GTSA 2HA8A 3CZBA 2O3AA 5DM6S 2V3JA 4CNEA 1DFUP 4RG1A 4YQKA 1O6DA
chains in the Genus database with same CATH topology
4PZKA 4YQGA 1VHKA 2NWAA 3AI9X 4YQOA 3DCMX 4H3YA 4YQ5A 3L8UA 4JWGA 5GMCA 4YQ6A 1NXZA 4YQPA 4YPXA 3OIIA 4XBOA 4YPWA 1X7PA 5FAIA 4IG6A 4YQIA 3KW2A 4JWHA 4YQ3A 2QMMA 3BBEA 4YQLA 1NS5A 4H3ZA 4FAKA 1J85A 4CNFA 3BBDA 4MCCA 5D9FA 4L69A 4YPZA 4YQ9A 4YQ1A 1X7OA 4YQCA 2YY8A 1Z85A 1UAJA 1UAMA 4FMWA 4YQ4A 3ONPA 5GM8A 4MCBA 2EGVA 4YQRA 2EGWA 4YQAA 3OIJA 3IC6A 4JWJA 4KDZA 4X3LA 4YVKA 3QUVA 2CX8A 4YQDA 1K3RA 1IPAA 4YQJA 3N4KA 4YVIA 3GYQA 4KGNA 1P9PA 4YQ0A 1ZJRA 1V2XA 4X3MA 4YQ2A 1OY5A 4YQBA 4J3CA 3N4JA 4MCDA 4YQNA 4JALA 5CO4A 1UALA 4JWFA 2I6DA 4YQSA 2Z0YA 4YQQA 4YQ7A 4CNGA 4JAKA 5GMBA 3AIAA 1V6ZA 3IEFA 2QWVA 3AXZA 3ILKA 1VHYA 4YVGA 4YVJA 3E5YA 1GZ0A 4YQ8A 3OINA 3NK7A 3KY7A 3KTYA 4CNDA 3KNUA 3NK6A 3BBHA 4YQTA 2V3KA 4YVHA 1VH0A 1UAKA 3O7BA 4YPYA 1MXIA 1TO0A 4E8BA 2HA8A 2O3AA 2V3JA 4CNEA 4RG1A 4YQKA 1O6DA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4PZK A;  4YQG A;  1VHK A;  2NWA A;  3AI9 X;  4YQO A;  3DCM X;  4H3Y A;  4YQ5 A;  3L8U A;  5GMC A;  4YQ6 A;  1NXZ A;  4YQP A;  4YPX A;  3OII A;  4XBO A;  4YPW A;  1X7P A;  5FAI A;  4IG6 A;  4YQI A;  3KW2 A;  4YQ3 A;  2QMM A;  3BBE A;  4YQL A;  1NS5 A;  4H3Z A;  4FAK A;  1J85 A;  4CNF A;  3BBD A;  4MCC A;  5D9F A;  4L69 A;  4YPZ A;  4YQ9 A;  4YQ1 A;  1X7O A;  4YQC A;  2YY8 A;  1Z85 A;  1UAJ A;  1UAM A;  4YQ4 A;  3ONP A;  5GM8 A;  4MCB A;  2EGV A;  4YQR A;  2EGW A;  4YQA A;  3OIJ A;  3IC6 A;  4KDZ A;  4X3L A;  4YVK A;  3QUV A;  2CX8 A;  4YQD A;  1K3R A;  1IPA A;  4YQJ A;  3N4K A;  4YVI A;  3GYQ A;  4KGN A;  1P9P A;  4YQ0 A;  1ZJR A;  1V2X A;  4X3M A;  4YQ2 A;  1OY5 A;  4YQB A;  4J3C A;  3N4J A;  4MCD A;  4YQN A;  4JAL A;  5CO4 A;  1UAL A;  2I6D A;  4YQS A;  2Z0Y A;  4YQQ A;  4YQ7 A;  4CNG A;  4JAK A;  5GMB A;  3AIA A;  1V6Z A;  3IEF A;  2QWV A;  3AXZ A;  3ILK A;  1VHY A;  4YVG A;  4YVJ A;  3E5Y A;  1GZ0 A;  4YQ8 A;  3OIN A;  3NK7 A;  3KY7 A;  3KTY A;  4CND A;  3KNU A;  3NK6 A;  3BBH A;  4YQT A;  2V3K A;  4YVH A;  1VH0 A;  1UAK A;  3O7B A;  4YPY A;  1MXI A;  1TO0 A;  4E8B A;  2HA8 A;  2O3A A;  2V3J A;  4CNE A;  4RG1 A;  4YQK A;  1O6D A; 
#chains in the Genus database with same CATH topology
 4PZK A;  3W2W B;  4YQG A;  1VHK A;  2NWA A;  3AI9 X;  4YQO A;  3AII A;  2RD2 A;  4H4K A;  3DCM X;  4H3Y A;  4YQ5 A;  3J7Z V;  5GAG W;  3L8U A;  4JWG A;  5GMC A;  5GAH W;  4WFB S;  4YQ6 A;  2PNW A;  1NXZ A;  4YQP A;  2PIC A;  4YPX A;  3OII A;  4XBO A;  5JVH S;  1QRS A;  5HL7 S;  1X7P A;  4YPW A;  5FAI A;  2GAE A;  4IG6 A;  5JVG S;  4YQI A;  3KW2 A;  4JWH A;  4YQ3 A;  2QMM A;  3BBE A;  4YQL A;  1NS5 A;  2G6G A;  2RE8 A;  1EUY A;  4H3Z A;  3CF5 S;  4FAK A;  1UDX A;  1J85 A;  4CNF A;  1NYL A;  3PIO S;  3BBD A;  4MCC A;  3X1L B;  5D9F A;  1QRU A;  3DLL S;  2PI8 A;  4L69 A;  4YPZ A;  5BNZ A;  2ZJQ S;  1QTQ A;  4YQ9 A;  4YQ1 A;  1X7O A;  4YQC A;  4JXX A;  2YY8 A;  1Z85 A;  1UAJ A;  1UAM A;  4FMW A;  4YQ4 A;  3ONP A;  5GM8 A;  4MCB A;  4H3S A;  4UY8 8;  2EGV A;  4YQR A;  2EGW A;  1EUQ A;  4YQA A;  5IZN A;  4WFA S;  3OIJ A;  3IC6 A;  4JWJ A;  2ZJP S;  4KDZ A;  4X3L A;  4YVK A;  4WCE S;  3QUV A;  4WF9 S;  2CX8 A;  4U67 S;  4IOA S;  4YQD A;  1K3R A;  1IPA A;  1D6K A;  4YQJ A;  1FEU A;  3N4K A;  4YVI A;  1EXD A;  3GYQ A;  4KGN A;  1P9P A;  4YQ0 A;  1ZJR A;  2PJJ A;  4V19 4;  1V2X A;  4X3M A;  4YQ2 A;  1OY5 A;  4YQB A;  4IO9 S;  4J3C A;  4JYZ A;  3N4J A;  4MCD A;  4YQN A;  2HZ7 A;  1B75 A;  2G5D A;  4JAL A;  5CO4 A;  1UAL A;  5GAE W;  4JWF A;  2I6D A;  3PIP S;  4YQS A;  2Z0Y A;  4WFN S;  4YQQ A;  4YQ7 A;  4CNG A;  4JAK A;  5GMB A;  3AIA A;  2ZJR S;  1V6Z A;  3IEF A;  4JXZ A;  2QWV A;  3AXZ A;  3ILK A;  2AE0 X;  1VHY A;  4YVG A;  5GAD W;  4P2B A;  1GTR A;  1ZJW A;  4YVJ A;  1QRT A;  3E5Y A;  1GZ0 A;  4YQ8 A;  3OIN A;  3NK7 A;  3KY7 A;  3KTY A;  4CND A;  5DM7 S;  3KNU A;  3NK6 A;  3BBH A;  1O0C A;  4YQT A;  2V3K A;  4YVH A;  1VH0 A;  1UAK A;  4IOC S;  1O0B A;  3O7B A;  3W2V B;  1MXI A;  4YPY A;  1TO0 A;  4E8B A;  1GTS A;  2HA8 A;  3CZB A;  2O3A A;  5DM6 S;  2V3J A;  4CNE A;  1DFU P;  4RG1 A;  4YQK A;  1O6D A; 
#chains in the Genus database with same CATH homology
 4PZK A;  4YQG A;  1VHK A;  2NWA A;  3AI9 X;  4YQO A;  3DCM X;  4H3Y A;  4YQ5 A;  3L8U A;  4JWG A;  5GMC A;  4YQ6 A;  1NXZ A;  4YQP A;  4YPX A;  3OII A;  4XBO A;  4YPW A;  1X7P A;  5FAI A;  4IG6 A;  4YQI A;  3KW2 A;  4JWH A;  4YQ3 A;  2QMM A;  3BBE A;  4YQL A;  1NS5 A;  4H3Z A;  4FAK A;  1J85 A;  4CNF A;  3BBD A;  4MCC A;  5D9F A;  4L69 A;  4YPZ A;  4YQ9 A;  4YQ1 A;  1X7O A;  4YQC A;  2YY8 A;  1Z85 A;  1UAJ A;  1UAM A;  4FMW A;  4YQ4 A;  3ONP A;  5GM8 A;  4MCB A;  2EGV A;  4YQR A;  2EGW A;  4YQA A;  3OIJ A;  3IC6 A;  4JWJ A;  4KDZ A;  4X3L A;  4YVK A;  3QUV A;  2CX8 A;  4YQD A;  1K3R A;  1IPA A;  4YQJ A;  3N4K A;  4YVI A;  3GYQ A;  4KGN A;  1P9P A;  4YQ0 A;  1ZJR A;  1V2X A;  4X3M A;  4YQ2 A;  1OY5 A;  4YQB A;  4J3C A;  3N4J A;  4MCD A;  4YQN A;  4JAL A;  5CO4 A;  1UAL A;  4JWF A;  2I6D A;  4YQS A;  2Z0Y A;  4YQQ A;  4YQ7 A;  4CNG A;  4JAK A;  5GMB A;  3AIA A;  1V6Z A;  3IEF A;  2QWV A;  3AXZ A;  3ILK A;  1VHY A;  4YVG A;  4YVJ A;  3E5Y A;  1GZ0 A;  4YQ8 A;  3OIN A;  3NK7 A;  3KY7 A;  3KTY A;  4CND A;  3KNU A;  3NK6 A;  3BBH A;  4YQT A;  2V3K A;  4YVH A;  1VH0 A;  1UAK A;  3O7B A;  4YPY A;  1MXI A;  1TO0 A;  4E8B A;  2HA8 A;  2O3A A;  2V3J A;  4CNE A;  4RG1 A;  4YQK A;  1O6D A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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