2IUCA

Structure of alkaline phosphatase from the antarctic bacterium tab5
Total Genus 133
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
133
Knots found
sequence length
344
structure length
340
Chain Sequence
KTPKNVILLISDGAGLSQISSTFYFKEGTPNYTQFKNIGLIKTSSSREDVTDSASGATAFSCGIKTYNAAIGVADDSTAVKSIVEIAALNNIKTGVVATSSITHATPASFYAHALNRGLEEEIAMDMTESDLDFFAGGGLNYFTSRKDKKDVLAILKGNQFTINTTGLTDFSSIASNRKMGFLLADEAMPTMESGRGNFLSAATDLAIQFLSKDNSAFFIMSEGSQIDWGGHANNASYLISEINDFDDAIGTALAFAKKDGNTLVIVTSDHETGGFTLAAKKNKREYSDYTSIGPSFSTGGHSATLIPVFAYGPGSEEFIGIYENNEIFHKILKVTKWNQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of Alkaline Phosphatase from the Antarctic Bacterium Tab5.
pubmed doi rcsb
molecule tags Hydrolase
source organism Antarctic bacterium tab5
molecule keywords ALKALINE PHOSPHATASE
total genus 133
structure length 340
sequence length 344
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.1.3.1: Alkaline phosphatase.
pdb deposition date 2006-06-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00245 Alk_phosphatase Alkaline phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 2iucA00
1ED9A 1E1ZP 1KHLA 1ELZA 1ALKA 1ED8A 1SHQA 1E3CP 1ALIA 2W5WA 3M7VA 1AJCA 1ANJA 2GLQA 4LRCA 3T01A 3LXQA 3UNYA 5LRMA 4LQYA 1KH9A 1EJJA 4KAVA 4UPKA 5EGHA 3SZYA 1KHKA 2ZKTA 5IJQA 3T02A 2VQRA 2IUCA 3MK2A 2D1GA 4FDIA 1AJDA 4MY4A 4CXUA 3M8YA 4GTWA 4KM4A 5LQQA 3TG0A 4B56A 4CXSA 3NKPA 5L0KA 4KJDA 2QZUA 4LRAA 3IGYB 3BDGB 5TJ3A 1AJBA 4GTXA 2GSUA 2XRGA 3A52A 4LRBA 1KHNA 4CXKA 3OT9A 1ZEDA 4UPIA 2W5RA 4GTYA 2XR9A 1Y7AA 4KAYA 1HQAA 1EW8A 4TN0A 3WBHA 5L0EA 1ALJA 3BDFA 2X98A 4ZG7A 4QAXA 4N7TA 4UPLA 3Q3QA 4LRFA 2ANHA 3NKQA 1HJKA 3ED4A 4KJGA 4LR7A 2W8SA 3WAYA 5LIAA 3E2DA 2W5TA 2W5SA 4LR2A 5C66A 1AJAA 1O99A 3WAWA 4MIVA 5AJ9A 2IUCB 3NKMA 3T00A 1EW9A 1EW2A 4FDJA 3IDDA 4ZG6A 1ALHA 4CYRA 4ZGAA 4UPHA 3WAVA 3UN5A 5HRTA 1ELXA 1P49A 1FSUA 2GSNA 1EI6A 3TWZA 3TX0A 3M8WA 5DLVA 5LRNA 2W5XA 2W5QA 1AUKA 2GA3A 3NKRA 4UOOA 1E33P 1K7HA 3UO0A 2RH6A 1ZEBA 4MHXA 4NWXA 1HDHA 3M8ZA 5KXAA 4YR1A 5DLTA 4GTZA 3BDHA 4NWJA 1URAA 4LRDA 3CMRA 1Y6VA 5EGEA 5IJSA 2IFYA 4UOPA 3NVLA 5K4PA 4UORA 1ELYA 5GRRA 1EQJA 5L0BA 2W5VA 3WAXA 3UN2A 1N2KA 1KH7A 1URBA 5DLWA 4CYSA 1E2SP 1O98A 3NKNA 3DYCA 3MK1A 1KHJA 2G9YA 3DPCA 1ZEFA 3BDGA 3MK0A 4LREA 1KH4A 1SHNA 4LR8A 1ANIA 5GOVA 1B8JA 4LR9A 2W8DA 2GSOA 3B5QA 3IGZB 5INHA 3UN3A 3SZZA 3NKOA 3KD8A 4ZG9A 1N2LA 1KH5A
chains in the Genus database with same CATH superfamily
1ED9A 1E1ZP 1KHLA 1ELZA 1ALKA 1ED8A 1SHQA 1E3CP 1ALIA 2W5WA 3M7VA 1AJCA 1ANJA 2GLQA 4LRCA 3T01A 3LXQA 3UNYA 5LRMA 4LQYA 1KH9A 1EJJA 4KAVA 4UPKA 5EGHA 3SZYA 1KHKA 2ZKTA 5IJQA 3T02A 2VQRA 2IUCA 3MK2A 2D1GA 4FDIA 1AJDA 4MY4A 4CXUA 3M8YA 4GTWA 4KM4A 5LQQA 3TG0A 4B56A 4CXSA 3NKPA 5L0KA 4KJDA 2QZUA 4LRAA 3IGYB 3BDGB 5TJ3A 1AJBA 4GTXA 2GSUA 2XRGA 3A52A 4LRBA 1KHNA 4CXKA 3OT9A 1ZEDA 4UPIA 2W5RA 4GTYA 2XR9A 1Y7AA 4KAYA 1HQAA 1EW8A 4TN0A 3WBHA 5L0EA 1ALJA 3BDFA 2X98A 4ZG7A 4QAXA 4N7TA 4UPLA 3Q3QA 4LRFA 2ANHA 3NKQA 1HJKA 3ED4A 4KJGA 4LR7A 2W8SA 3WAYA 5LIAA 3E2DA 2W5TA 2W5SA 4LR2A 5C66A 1AJAA 1O99A 3WAWA 4MIVA 5AJ9A 2IUCB 3NKMA 3T00A 1EW9A 1EW2A 4FDJA 3IDDA 4ZG6A 1ALHA 4CYRA 4ZGAA 4UPHA 3WAVA 3UN5A 5HRTA 1ELXA 1P49A 1FSUA 2GSNA 1EI6A 3TWZA 3TX0A 3M8WA 5DLVA 5LRNA 2W5XA 2W5QA 1AUKA 2GA3A 3NKRA 4UOOA 1E33P 1K7HA 3UO0A 2RH6A 1ZEBA 4MHXA 4NWXA 1HDHA 3M8ZA 5KXAA 4YR1A 5DLTA 4GTZA 3BDHA 4NWJA 1URAA 4LRDA 3CMRA 1Y6VA 5EGEA 5IJSA 2IFYA 4UOPA 3NVLA 5K4PA 4UORA 1ELYA 5GRRA 1EQJA 5L0BA 2W5VA 3WAXA 3UN2A 1N2KA 1KH7A 1URBA 5DLWA 4CYSA 1E2SP 1O98A 3NKNA 3DYCA 3MK1A 1KHJA 2G9YA 3DPCA 1ZEFA 3BDGA 3MK0A 4LREA 1KH4A 1SHNA 4LR8A 1ANIA 5GOVA 1B8JA 4LR9A 2W8DA 2GSOA 3B5QA 3IGZB 5INHA 3UN3A 3SZZA 3NKOA 3KD8A 4ZG9A 1N2LA 1KH5A
chains in the Genus database with same CATH topology
1ED9A 1E1ZP 1KHLA 1ELZA 1ALKA 1ED8A 1SHQA 1E3CP 1ALIA 2W5WA 3M7VA 1AJCA 1ANJA 2GLQA 4LRCA 3T01A 3LXQA 3UNYA 5LRMA 4LQYA 1KH9A 1EJJA 4KAVA 4UPKA 5EGHA 3SZYA 1KHKA 2ZKTA 5IJQA 3T02A 2VQRA 2IUCA 3MK2A 2D1GA 4FDIA 1AJDA 4MY4A 4CXUA 3M8YA 4GTWA 4KM4A 5LQQA 3TG0A 4B56A 4CXSA 3NKPA 5L0KA 4KJDA 2QZUA 4LRAA 3IGYB 3BDGB 5TJ3A 1AJBA 4GTXA 2GSUA 2XRGA 3A52A 4LRBA 1KHNA 4CXKA 3OT9A 1ZEDA 4UPIA 2W5RA 4GTYA 2XR9A 1Y7AA 4KAYA 1HQAA 1EW8A 4TN0A 3WBHA 5L0EA 1ALJA 3BDFA 2X98A 4ZG7A 4QAXA 4N7TA 4UPLA 3Q3QA 4LRFA 2ANHA 3NKQA 1HJKA 3ED4A 4KJGA 4LR7A 2W8SA 3WAYA 5LIAA 3E2DA 2W5TA 2W5SA 4LR2A 5C66A 1AJAA 1O99A 3WAWA 4MIVA 5AJ9A 2IUCB 3NKMA 3T00A 1EW9A 1EW2A 4FDJA 3IDDA 4ZG6A 1ALHA 4CYRA 4ZGAA 4UPHA 3WAVA 3UN5A 5HRTA 1ELXA 1P49A 1FSUA 2GSNA 1EI6A 3TWZA 3TX0A 3M8WA 5DLVA 5LRNA 2W5XA 2W5QA 1AUKA 2GA3A 3NKRA 4UOOA 1E33P 1K7HA 3UO0A 2RH6A 1ZEBA 4MHXA 4NWXA 1HDHA 3M8ZA 5KXAA 4YR1A 5DLTA 4GTZA 3BDHA 4NWJA 1URAA 4LRDA 3CMRA 1Y6VA 5EGEA 5IJSA 2IFYA 4UOPA 3NVLA 5K4PA 4UORA 1ELYA 5GRRA 1EQJA 5L0BA 2W5VA 3WAXA 3UN2A 1N2KA 1KH7A 1URBA 5DLWA 4CYSA 1E2SP 1O98A 3NKNA 3DYCA 3MK1A 1KHJA 2G9YA 3DPCA 1ZEFA 3BDGA 3MK0A 4LREA 1KH4A 1SHNA 4LR8A 1ANIA 5GOVA 1B8JA 4LR9A 2W8DA 2GSOA 3B5QA 3IGZB 5INHA 3UN3A 3SZZA 3NKOA 3KD8A 4ZG9A 1N2LA 1KH5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ED9 A;  1E1Z P;  1KHL A;  1ELZ A;  1ALK A;  1ED8 A;  1SHQ A;  1E3C P;  1ALI A;  2W5W A;  3M7V A;  1AJC A;  1ANJ A;  2GLQ A;  4LRC A;  3T01 A;  3LXQ A;  3UNY A;  5LRM A;  4LQY A;  1KH9 A;  1EJJ A;  4KAV A;  4UPK A;  5EGH A;  3SZY A;  1KHK A;  2ZKT A;  5IJQ A;  3T02 A;  2VQR A;  2IUC A;  3MK2 A;  2D1G A;  4FDI A;  1AJD A;  4MY4 A;  4CXU A;  3M8Y A;  4GTW A;  4KM4 A;  5LQQ A;  3TG0 A;  4B56 A;  4CXS A;  3NKP A;  5L0K A;  4KJD A;  2QZU A;  4LRA A;  3IGY B;  3BDG B;  5TJ3 A;  1AJB A;  4GTX A;  2GSU A;  2XRG A;  3A52 A;  4LRB A;  1KHN A;  4CXK A;  3OT9 A;  1ZED A;  4UPI A;  2W5R A;  4GTY A;  2XR9 A;  1Y7A A;  4KAY A;  1HQA A;  1EW8 A;  4TN0 A;  3WBH A;  5L0E A;  1ALJ A;  3BDF A;  2X98 A;  4ZG7 A;  4QAX A;  4N7T A;  4UPL A;  3Q3Q A;  4LRF A;  2ANH A;  3NKQ A;  1HJK A;  3ED4 A;  4KJG A;  4LR7 A;  2W8S A;  3WAY A;  5LIA A;  3E2D A;  2W5T A;  2W5S A;  4LR2 A;  5C66 A;  1AJA A;  1O99 A;  3WAW A;  4MIV A;  5AJ9 A;  2IUC B;  3NKM A;  3T00 A;  1EW9 A;  1EW2 A;  4FDJ A;  3IDD A;  4ZG6 A;  1ALH A;  4CYR A;  4ZGA A;  4UPH A;  3WAV A;  3UN5 A;  5HRT A;  1ELX A;  1P49 A;  1FSU A;  2GSN A;  1EI6 A;  3TWZ A;  3TX0 A;  3M8W A;  5DLV A;  5LRN A;  2W5X A;  2W5Q A;  1AUK A;  2GA3 A;  3NKR A;  4UOO A;  1E33 P;  1K7H A;  3UO0 A;  2RH6 A;  1ZEB A;  4MHX A;  4NWX A;  1HDH A;  3M8Z A;  5KXA A;  4YR1 A;  5DLT A;  4GTZ A;  3BDH A;  4NWJ A;  1URA A;  4LRD A;  3CMR A;  1Y6V A;  5EGE A;  5IJS A;  2IFY A;  4UOP A;  3NVL A;  5K4P A;  4UOR A;  1ELY A;  5GRR A;  1EQJ A;  5L0B A;  2W5V A;  3WAX A;  3UN2 A;  1N2K A;  1KH7 A;  1URB A;  5DLW A;  4CYS A;  1E2S P;  1O98 A;  3NKN A;  3DYC A;  3MK1 A;  1KHJ A;  2G9Y A;  3DPC A;  1ZEF A;  3BDG A;  3MK0 A;  4LRE A;  1KH4 A;  1SHN A;  4LR8 A;  1ANI A;  5GOV A;  1B8J A;  4LR9 A;  2W8D A;  2GSO A;  3B5Q A;  3IGZ B;  5INH A;  3UN3 A;  3SZZ A;  3NKO A;  3KD8 A;  4ZG9 A;  1N2L A;  1KH5 A; 
#chains in the Genus database with same CATH topology
 1ED9 A;  1E1Z P;  1KHL A;  1ELZ A;  1ALK A;  1ED8 A;  1SHQ A;  1E3C P;  1ALI A;  2W5W A;  3M7V A;  1AJC A;  1ANJ A;  2GLQ A;  4LRC A;  3T01 A;  3LXQ A;  3UNY A;  5LRM A;  4LQY A;  1KH9 A;  1EJJ A;  4KAV A;  4UPK A;  5EGH A;  3SZY A;  1KHK A;  2ZKT A;  5IJQ A;  3T02 A;  2VQR A;  2IUC A;  3MK2 A;  2D1G A;  4FDI A;  1AJD A;  4MY4 A;  4CXU A;  3M8Y A;  4GTW A;  4KM4 A;  5LQQ A;  3TG0 A;  4B56 A;  4CXS A;  3NKP A;  5L0K A;  4KJD A;  2QZU A;  4LRA A;  3IGY B;  3BDG B;  5TJ3 A;  1AJB A;  4GTX A;  2GSU A;  2XRG A;  3A52 A;  4LRB A;  1KHN A;  4CXK A;  3OT9 A;  1ZED A;  4UPI A;  2W5R A;  4GTY A;  2XR9 A;  1Y7A A;  4KAY A;  1HQA A;  1EW8 A;  4TN0 A;  3WBH A;  5L0E A;  1ALJ A;  3BDF A;  2X98 A;  4ZG7 A;  4QAX A;  4N7T A;  4UPL A;  3Q3Q A;  4LRF A;  2ANH A;  3NKQ A;  1HJK A;  3ED4 A;  4KJG A;  4LR7 A;  2W8S A;  3WAY A;  5LIA A;  3E2D A;  2W5T A;  2W5S A;  4LR2 A;  5C66 A;  1AJA A;  1O99 A;  3WAW A;  4MIV A;  5AJ9 A;  2IUC B;  3NKM A;  3T00 A;  1EW9 A;  1EW2 A;  4FDJ A;  3IDD A;  4ZG6 A;  1ALH A;  4CYR A;  4ZGA A;  4UPH A;  3WAV A;  3UN5 A;  5HRT A;  1ELX A;  1P49 A;  1FSU A;  2GSN A;  1EI6 A;  3TWZ A;  3TX0 A;  3M8W A;  5DLV A;  5LRN A;  2W5X A;  2W5Q A;  1AUK A;  2GA3 A;  3NKR A;  4UOO A;  1E33 P;  1K7H A;  3UO0 A;  2RH6 A;  1ZEB A;  4MHX A;  4NWX A;  1HDH A;  3M8Z A;  5KXA A;  4YR1 A;  5DLT A;  4GTZ A;  3BDH A;  4NWJ A;  1URA A;  4LRD A;  3CMR A;  1Y6V A;  5EGE A;  5IJS A;  2IFY A;  4UOP A;  3NVL A;  5K4P A;  4UOR A;  1ELY A;  5GRR A;  1EQJ A;  5L0B A;  2W5V A;  3WAX A;  3UN2 A;  1N2K A;  1KH7 A;  1URB A;  5DLW A;  4CYS A;  1E2S P;  1O98 A;  3NKN A;  3DYC A;  3MK1 A;  1KHJ A;  2G9Y A;  3DPC A;  1ZEF A;  3BDG A;  3MK0 A;  4LRE A;  1KH4 A;  1SHN A;  4LR8 A;  1ANI A;  5GOV A;  1B8J A;  4LR9 A;  2W8D A;  2GSO A;  3B5Q A;  3IGZ B;  5INH A;  3UN3 A;  3SZZ A;  3NKO A;  3KD8 A;  4ZG9 A;  1N2L A;  1KH5 A; 
#chains in the Genus database with same CATH homology
 1ED9 A;  1E1Z P;  1KHL A;  1ELZ A;  1ALK A;  1ED8 A;  1SHQ A;  1E3C P;  1ALI A;  2W5W A;  3M7V A;  1AJC A;  1ANJ A;  2GLQ A;  4LRC A;  3T01 A;  3LXQ A;  3UNY A;  5LRM A;  4LQY A;  1KH9 A;  1EJJ A;  4KAV A;  4UPK A;  5EGH A;  3SZY A;  1KHK A;  2ZKT A;  5IJQ A;  3T02 A;  2VQR A;  2IUC A;  3MK2 A;  2D1G A;  4FDI A;  1AJD A;  4MY4 A;  4CXU A;  3M8Y A;  4GTW A;  4KM4 A;  5LQQ A;  3TG0 A;  4B56 A;  4CXS A;  3NKP A;  5L0K A;  4KJD A;  2QZU A;  4LRA A;  3IGY B;  3BDG B;  5TJ3 A;  1AJB A;  4GTX A;  2GSU A;  2XRG A;  3A52 A;  4LRB A;  1KHN A;  4CXK A;  3OT9 A;  1ZED A;  4UPI A;  2W5R A;  4GTY A;  2XR9 A;  1Y7A A;  4KAY A;  1HQA A;  1EW8 A;  4TN0 A;  3WBH A;  5L0E A;  1ALJ A;  3BDF A;  2X98 A;  4ZG7 A;  4QAX A;  4N7T A;  4UPL A;  3Q3Q A;  4LRF A;  2ANH A;  3NKQ A;  1HJK A;  3ED4 A;  4KJG A;  4LR7 A;  2W8S A;  3WAY A;  5LIA A;  3E2D A;  2W5T A;  2W5S A;  4LR2 A;  5C66 A;  1AJA A;  1O99 A;  3WAW A;  4MIV A;  5AJ9 A;  2IUC B;  3NKM A;  3T00 A;  1EW9 A;  1EW2 A;  4FDJ A;  3IDD A;  4ZG6 A;  1ALH A;  4CYR A;  4ZGA A;  4UPH A;  3WAV A;  3UN5 A;  5HRT A;  1ELX A;  1P49 A;  1FSU A;  2GSN A;  1EI6 A;  3TWZ A;  3TX0 A;  3M8W A;  5DLV A;  5LRN A;  2W5X A;  2W5Q A;  1AUK A;  2GA3 A;  3NKR A;  4UOO A;  1E33 P;  1K7H A;  3UO0 A;  2RH6 A;  1ZEB A;  4MHX A;  4NWX A;  1HDH A;  3M8Z A;  5KXA A;  4YR1 A;  5DLT A;  4GTZ A;  3BDH A;  4NWJ A;  1URA A;  4LRD A;  3CMR A;  1Y6V A;  5EGE A;  5IJS A;  2IFY A;  4UOP A;  3NVL A;  5K4P A;  4UOR A;  1ELY A;  5GRR A;  1EQJ A;  5L0B A;  2W5V A;  3WAX A;  3UN2 A;  1N2K A;  1KH7 A;  1URB A;  5DLW A;  4CYS A;  1E2S P;  1O98 A;  3NKN A;  3DYC A;  3MK1 A;  1KHJ A;  2G9Y A;  3DPC A;  1ZEF A;  3BDG A;  3MK0 A;  4LRE A;  1KH4 A;  1SHN A;  4LR8 A;  1ANI A;  5GOV A;  1B8J A;  4LR9 A;  2W8D A;  2GSO A;  3B5Q A;  3IGZ B;  5INH A;  3UN3 A;  3SZZ A;  3NKO A;  3KD8 A;  4ZG9 A;  1N2L A;  1KH5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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